Clinical trials: Change; Retina
Cataract, Diabetic Retinopathy
Diabetic Retinopathy and OCT-A Changes Post-cataract Surgery
The purpose of this study is to use optical coherence tomography angiography (OCT-A) to compare retinal vasculature after uncomplicated cataract surgery in patients with and without diabetic retinopathy.
- Conditions
- Cataract, Diabetic Retinopathy, Macular Edema Due to Diabetes Mellitus
- Trial name
- NCT04660006
- Testing
- Cataract surgery
- Where
- Canada
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Uptown Eye Specialists
Macular Holes
Macular Micro Vascular Changes Following Macular Hole Repair : Optical Coherence Tomography Angiography Study
The goal of this prospective interventional study is to to compare the micro vascular and structural changes between surgery with and without ILM flap to repair macular hole.
- Trial name
- NCT06233500
- Testing
- pars plana vitrectomy
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Fayoum University
Myopia
Pharmacological and Non-pharmacological Treatment Effects on Children With Different Predicted Myopia Progression Rate
The goal of this clinical trial is to compare pharmacological and non-pharmacological treatment effects on the children with different predicted myopia progression rate measured by modified multifocal electroretinogram.
- Trial name
- NCT06282848
- Testing
- Atropine 0.05%, DIMS lens
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Amblyopia
Changes in Amblyopia Using Optical Coherence Tomography
There have been multiple trials to investigate the morphological changes in the macula and retinal nerve fiber layer of amblyopic eyes, due to the different published results and the lack of evident association between these…
- Trial name
- NCT04092361
- Testing
- optical coherence tomography
- Volunteers
- 28 people
- Sponsor
- Assiut University
Retinopathy of Prematurity
Changes in Vital Signs and Pupil Diameter Related to Pharmacologic Mydriasis in Premature Infants: A Randomized Double Blind Clinical Study
Retinopathy of prematurity (ROP) is one of the common anatomic causes of blindness among Filipinos, accounting for 47.7% of the cases.
- Trial name
- NCT04838665
- Testing
- 0.5% cyclopentolate and 2.5% phenylephrine, 0.5% tropicamide + 0.5% phenylephrine, 0.5% tropicamide + 0.5% phenylephrine with a cotton wick
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of the Philippines
BPD - Bronchopulmonary Dysplasia, NEC - Necrotizing Enterocolitis
Targeted vs Standard Fortification of Breast Milk
BACKGROUND: Human milk (HM) is recommended for all very low birth infants (VLBW)). Breast-milk is highly variable in nutrient content, failing to meet the nutritional demands of VLBW.
- Conditions
- BPD - Bronchopulmonary Dysplasia, NEC - Necrotizing Enterocolitis, Weight Gain, VLBW - Very Low Birth Weight Infant
- Trial name
- NCT03775785
- Testing
- Tailored enteral nutrition
- Where
- 2 sites in Poland
- Volunteers
- 200 people
- Sponsor
- Princess Anna Mazowiecka Hospital, Warsaw, Poland
Maculopathy
Assessment Of Diabetic Maculopathy Changes After Phacoemulsification by Using Optical Coherence Tomography
Investigators aimed to assess the macular changes with OCT after uncomplicated phacoemulsification surgery in diabetic patients with non proliferative diabetic retinopathy (NPDR) at the time of surgery and the effect of…
- Trial name
- Maculopathy (NCT05547789)
- Testing
- non steroidal anti inflammatory drugs
- Where
- 2 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Optic Neuritis
Effect of Vitamin D on Retinal Changes in Patient With Optic Neuritis by Optic Coherence Tomography
This study examines the effect of vitamin D on Retinal changes in patient with optic Neuritis.
- Trial name
- NCT01465893
- Testing
- Vitamin D, Vitamin D withheld
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Isfahan University of Medical Sciences
Pediatric Disorder, Vitamin D Deficiency
Retinal Changes in Vitamin D Deficiency
Retinal tissue parameters of pediatric patients with vitamin D deficiency will be evaluated in this prospective case-control study. The patients will be divided into 2 groups according to the vitamin D level.
- Conditions
- Pediatric Disorder, Vitamin D Deficiency, Retinal Disease, Choroidal Disease
- Trial name
- VDD (NCT04891211)
- Testing
- Vitamin D deficiency
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Adiyaman University
Diabetic Retinopathy (DR), Retinal Microvascular Changes
Relation Between Glycemic Control and Retinal Microvascular Changes in Diabetic Patients Using OCTA
An observational cross-sectional comparative study which will be conducted in the Department of Ophthalmology, Sohag University Hospital, Egypt to detect the relation between glycemic control and retinal microvascular changes in…
- Trial name
- Retinopathy (NCT07726381)
- Volunteers
- 50 people
- Sponsor
- Sohag University
Eye Diseases, Hereditary
Fundus Changes in the Microphthalmy Eyes
The goal is to describe the fundamental aspects of fundoscopic eye in patients with microphthalmia
- Trial name
- NCT00811512
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Hospital de Olhos Sadalla Amin Ghanem
Rhegmatogenous Macula-off Retinal Detachment
Corneal Endothelial Cell Changes In Silicon Filled Eye
The aim of this study is to evaluate corneal endothelial cell changes after pars plana vitrectomy in Rhegmatogenous Retinal detachment , compare the results using different silicon oil viscositites , and assess whether these…
- Trial name
- Endothelium (NCT07418606)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Minia University
Diabetic Retinopathy, Type 1 Diabetes
Effect of Omega-3 Fatty Acids on Eye Blood Vessels in Type 1 Diabetes
This double-blind, placebo-controlled randomized clinical trial evaluates the effects of omega-3 fatty acid supplementation on retinal vascular structure and function in children and adolescents with type 1 diabetes.
- Conditions
- Diabetic Retinopathy, Type 1 Diabetes, Omega 3 Fatty Acids
- Trial name
- O3RETINA (NCT07255326)
- Testing
- Omega 3 Fish Oil supplements
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- University of Faisalabad
Myopia, Myopia; Refractive Error
Peripheral Relative Refractive Power of Orthokeratology Lenses
Orthokeratology (OK) has been demonstrated to be an effective intervention for slowing axial elongation in children with myopia.
- Trial name
- NCT07294404
- Testing
- orthokeratology
- Where
- China
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia, Refractive Errors
Effect of Repeated Low-Level Red-Light Therapy on Retinal Function and Structure
The purpose of this clinical trial is to evaluate the effect of repeated low-level red-light (RLRL) therapy on the retinal function and structure among myopic teenagers.
- Conditions
- Myopia, Refractive Errors, Eye Diseases, Retina; Change
- Trial name
- NCT05597397
- Testing
- RLRL
- Where
- China
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center