Clinical trials: Childhood Pneumonia
Community-acquired Pneumonia
pedCAPNETZ - Community Acquired Pneumonia (CAP) in Childhood and Adolescence
Establishment of a study network and patient cohort for pediatric CAP
- Trial name
- pedCAPNETZ (NCT04047108)
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- Hannover Medical School
Pneumonia
Amoxicillin Versus Benzyl Penicillin for Treatment of Children Hospitalised With Severe Pneumonia
This study seeks to determine whether clinical outcome following initial treatment of severe pneumonia with oral amoxicillin is as effective as the current standard benzyl penicillin.
- Trial name
- NCT01399723
- Testing
- Amoxicillin, Benzyl penicillin
- Where
- 6 sites in Kenya
- Volunteers
- 561 people
- Sponsor
- KEMRI-Wellcome Trust Collaborative Research Program
Respiratory Tract Infections, Pneumonia
Randomised Exposure Study of Pollution Indoors and Respiratory Effects
The purpose of this study was to determine whether reduced exposure to indoor air pollution would reduce ALRI incidence in children <18 months of age.
- Trial name
- RESPIRE (NCT01047696)
- Testing
- Plancha
- Where
- Guatemala
- Volunteers
- 537 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
COVID-19, Childhood Cancer
COVID-19 and Childhood Cancer
The investigators will first examine the impact of the COVID-19 pandemic on childhood cancer patients in Sweden and Denmark, both regarding susceptibility to severe COVID-19 among long-term childhood cancer survivors, and, for…
- Conditions
- COVID-19, Childhood Cancer, Childhood Leukemia, Acute Lymphoblastic
- Trial name
- NCT06482281
- Where
- Sweden
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Pneumonia Childhood
Effectiveness Trial of Day-care vs. Usual Care of Severe Pneumonia & Malnutrition in Children
Background: At present pneumonia and malnutrition have become the leading causes of mortality among <5-year-old children in developing countries.
- Trial name
- Day-care (NCT02669654)
- Testing
- Day-care management of Severe Pneumonia
- Where
- 2 sites in Bangladesh
- Volunteers
- 4,000 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Community Acquired Pneumonia in Children, Mycoplasma Pneumoniae
A Trial of Placebo Versus Macrolide for Mycoplasma Pneumoniae Childhood Pneumonia: MYTHIC Study
The goal of this clinical trial is to compare a placebo (a look-alike substance that contains no active drug) with a commonly used antibiotic in children with Mycoplasma pneumoniae (a specific bacterium) induced…
- Conditions
- Community Acquired Pneumonia in Children, Mycoplasma Pneumoniae, Mycoplasma Pneumoniae Pneumonia
- Trial name
- MYTHIC (NCT06325293)
- Testing
- Azithromycin Pfizer®
- Where
- 13 sites in Switzerland
- Volunteers
- 376 people
- Sponsor
- Christoph Berger
Pneumonia, Childhood Pneumonia
Pneumonia Policy Formation in Pakistan
In Pakistan, numerous policies have been formulated in the past on pneumonia management translated into various programs. However, despite completion, the state of pneumonia mortality remains unchanged as no sustainable solutions…
- Trial name
- NCT03784274
- Testing
- Stakeholder analysis
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Edinburgh
Pneumonia, Primary Health Care
Tools for the Integrated Management of Childhood Illness (TIMCI): Evaluation of Pulse Oximetry & Clinical Decision Support Algorithms in Primary Care
By introducing pulse oximetry, with or without clinical decision support algorithms, to primary care facilities in India, Kenya, Senegal and Tanzania, the Tools for Integrated Management of Childhood Illness (TIMCI) project aims…
- Conditions
- Pneumonia, Primary Health Care, Child Health, Hypoxia
- Trial name
- TIMCI (NCT04910750)
- Testing
- Pulse oximetry, Clinical Decision Support Algorithm
- Where
- 27 sites in Tanzania
- Volunteers
- 167,517 people
- Sponsor
- Swiss Tropical & Public Health Institute
Childhood Anxiety Disorder, Childhood Depression
Brief Internet-delivered Intervention for Children and Adolescents With Anxiety and Depression Symptoms
Investigators developed a brief standardized internet-delivered cognitive-behavioral program for treating anxious and depressive symptoms in children and adolescents in the context of COVID-19 pandemics in Brazil.
- Trial name
- NCT05139433
- Testing
- Telepsychotherapy, Psychoeducational Videos
- Where
- Brazil
- Volunteers
- 280 people
- Sponsor
- University of Sao Paulo
Cancer
Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation
RATIONALE: Antivirals such as ribavirin are used to treat infections caused by viruses. It is not yet known if ribavirin is more effective with or without monoclonal antibody therapy in treating patients who develop RSV pneumonia…
- Trial name
- NCT00014391
- Testing
- palivizumab, ribavirin
- Where
- United States
- Sponsor
- Fred Hutchinson Cancer Center
Quality of Life (QOL), Patient-Reported Outcome Measures (PROMs)
Validation of the EQ-5D-Y-3L and EQ-5D-Y-5L for Paediatric Patients in China
The goal of this observational study is to validate the EQ-5D-Y-3L and EQ-5D-Y-5L in measuring health-related quality of life (HRQoL) for paediatric patients with different health conditions in China.
- Conditions
- Quality of Life (QOL), Patient-Reported Outcome Measures (PROMs), Pneumonia Childhood, Neuroblastoma (NB)
- Trial name
- NCT06873672
- Where
- China
- Volunteers
- 360 people
- Sponsor
- RenJi Hospital
Malnutrition, Pneumonia
Trial in Childhood Pneumonia With Malnutrition
The impetus for this study came from the findings of the investigators' recently published study entitled "Day-care management of severe and very severe pneumonia, without associated co-morbidities such as severe malnutrition, in…
- Trial name
- NCT00968370
- Testing
- Day-care clinic, Hospital Management
- Where
- Bangladesh
- Volunteers
- 440 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Childhood Pneumonia
Improving Paediatric Pneumonia Diagnosis Using Digital Auscultation
This study aims to evaluate an automated interpretation algorithm of recorded lung sound by a digital stethoscope, name the Smartscope, among rural Bangladeshi children receiving community care in order to improve the diagnosis…
- Trial name
- NCT03959956
- Testing
- Recording lung sound by a Smartscope
- Where
- Bangladesh
- Volunteers
- 990 people
- Sponsor
- University of Edinburgh
Health Behavior
Effect of Social Accountability on Improving Service Delivery and Outcomes in the Public Sector in Uttar Pradesh, India
In several low and middle-income countries, Social Accountability (SA) interventions have been introduced as an innovative approach to governance, aiming to improve delivery of public services.
- Trial name
- D0168 (NCT02879708)
- Testing
- Information Only, Information and Facilitation
- Where
- India
- Volunteers
- 105,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Lower Respiratory Infection, LRTI
Effectiveness of Point-of-care Lung Ultrasound for the Management of Childhood Lower Respiratory Infections
The goal of this clinical trial is to evaluate the effectiveness of point-of-care lung ultrasound versus chest X-ray for the management of childhood lower respiratory infections in a low-resource setting.
- Conditions
- Lower Respiratory Infection, LRTI, Pneumonia, Bronchiolitis
- Trial name
- ELUS (NCT05921526)
- Testing
- Point-of-care lung ultrasound, Chest X-ray (digital images)
- Where
- Nepal
- Volunteers
- 616 people
- Sponsor
- Nagasaki University
Pneumonia
Host Response and Pathogen Genomics in Childhood Respiratory Infection
A major challenge in children's infections is that it is difficult to work out which bug is making them unwell. Tests can find the bugs that are present though there can be more than one.
- Trial name
- INTERACT (NCT07545096)
- Testing
- Non-Interventional Study
- Volunteers
- 50 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Pneumonia Childhood
Thoracic KT on Pulmonary Function Ichildren with Pneumonia
This study aimed to investigate the effect of thoracic kinesio-tape on Pulmonary Functions, time to clinical resolution and respiratory rate and arterial oxygen saturation in children with pneumonia.
- Trial name
- NCT06573047
- Testing
- kinesotape, Chest physiotherapy exercises
- Volunteers
- 40 people
- Sponsor
- Cairo University
Childhood Pneumonia
Prophylactic Sodium Supplementation for Children Hospitalized With Pneumonia
The goal of this clinical trial is to study the impact of sodium supplementation on hospital outcomes of children with pneumonia.
- Trial name
- NCT06951347
- Testing
- Oral Rehydration Solution
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- General Organization for Teaching Hospitals and Institutes
Pneumonia Childhood, Vitamin C
Effect of Vitamin C on Length of Hospital Stay in Children With Severe Pneumonia
Severe pneumonia is a common and serious illness in young children and often requires hospital admission. This clinical trial aims to find out whether adding vitamin C to standard treatment can reduce the length of hospital stay…
- Conditions
- Pneumonia Childhood, Vitamin C, Hospital Stay Time
- Trial name
- NCT07414693
- Testing
- Antibiotics administration, Vitamin C
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Children's Hospital and Institute of Child Health, Multan
Childhood Diarrhea, Childhood Pneumonia
Community Mobilization and Incentivization for Childhood Diarrhea and Pneumonia
Childhood diarrhea and pneumonia remains the leading cause of mortality among children under five years of age in Pakistan. The prevalence of diarrhea in Pakistan has increased from 15% in 1990 to 23% in 2013 while there has been…
- Conditions
- Childhood Diarrhea, Childhood Pneumonia, Community Mobilisation, Sanitation and Hygiene
- Trial name
- CoMIC (NCT03594279)
- Testing
- Community Mobilization, Community Mobilization and Community Incentive
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Aga Khan University