Clinical trials: Choice Behavior
Medullary Thyroid Cancer
A Study of Selpercatinib (LY3527723) in Participants With RET-Mutant Medullary Thyroid Cancer
The reason for this study is to see if the study drug selpercatinib is safe and more effective compared to a standard treatment in participants with rearranged during transfection (RET)-mutant medullary thyroid cancer (MTC) that…
- Trial name
- LIBRETTO-531 (NCT04211337)
- Testing
- Selpercatinib, Cabozantinib, Vandetanib
- Where
- 143 sites in United States, Australia and 18 more
- Volunteers
- 291 people
- Sponsor
- Loxo Oncology, Inc.
Rectal Neoplasms
Choice of the Optimal Treatment Strategies for Mid-low REctal Cancer
The purpose of this study is to compare the efficacy, prognosis, health economics of different treatment modalities of mid-low rectal cancer in different centers in China, and to conduct cost utility analysis (CUA) on the…
- Trial name
- COMREC (NCT05871762)
- Testing
- Registry study, no specific intervention
- Where
- China
- Volunteers
- 3,705 people
- Sponsor
- Peking Union Medical College Hospital
Obesity, Overweight
Behavioral Economics and Food Choice
This is the second in a series of pilot interventions we are conducting to assess how principles from behavioral economics can be applied to improve consumers' food choices.
- Trial name
- NCT01061905
- Testing
- Calorie information, Exercise Equivalent only, Calorie & Exercise equivalent information
- Where
- 4 sites in United States
- Volunteers
- 4 people
- Sponsor
- University of Pennsylvania
Knowledge, Attitudes, Practice
Assessment of Knowledge, Attitude and Practice of Eligible Couples Regarding Eugenics
A Descriptive study to assess the knowledge, attitude and practice regarding eugenics among eligible couples of selected area of Ambala, Haryana, India.
- Trial name
- NCT03237559
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- Maharishi Markendeswar University (Deemed to be University)
Retinoblastoma, Chemotherapy Effect
Topotecan and Melphalan for Retinoblastoma
The purpose of this study is to evaluate topotecan and melphalan for retinoblastoma patients.
- Trial name
- NCT04799002
- Testing
- Topotecan, Melphalan
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Sun Yat-sen University
Atopic Dermatitis
Taking Into Account the Patient/Parent Preference in the Galenic Choice in Atopic Dermatitis. Feasibility and Impact on Treatment Adherence
Atopic dermatitis is a chronic inflammatory skin disease often occurring in childhood. The treatment consists in making daily local treatment with topical steroid on inflammatory lesions and emollient on the whole body.
- Trial name
- DACE (NCT02193230)
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Nantes University Hospital
Lung Neoplasms
DeniLA: Comprehensive Demographics and Clinical Profile of NSCLC Patients: Analyzing Guideline-Concordant Care in First-line Treatment Patterns
This is a prospective, observational, multicenter study, in which clinical and demographic data will be extracted from medical records.
- Trial name
- DeniLA (NCT07109154)
- Where
- 7 sites in Brazil
- Volunteers
- 200 people
- Sponsor
- AstraZeneca
Weight Loss, Overweight and Obesity
Choosing Healthy Activities and Lifestyle Management Through Portal Support
The study aims to randomize 250 participants to 1 of 2 arms: a.) an Active Intervention Group (based on the Look AHEAD* ILI) or b.) a Comparison Group (based on the Look AHEAD DSE Comparison group) to test the hypothesis that a…
- Conditions
- Weight Loss, Overweight and Obesity, Behavior, Health
- Trial name
- CHAMPS (NCT05410353)
- Testing
- Active Intervention Group, Comparison Group
- Where
- United States
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Obesity, Food Selection
Using Single and Combined Nudge Strategies to Promote Healthier Beverage Intake Among College Students
The primary objective of this study was to examine whether three nudging strategies influence beverage consumption behavior among Chinese university students.
- Trial name
- NCT07625969
- Testing
- choice architecture
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Nanjing Medical University
HIV
A Study to Evaluate the Acceptability and Preference for Contraceptive Options as Proxy for HIV Prevention Methods
This study will enrol sexually active, healthy girls aged 16-17 to assess and compare the acceptability and preference for a monthly vaginal ring, bi-monthly injectable contraception or daily dose oral contraception, as proxy for…
- Trial name
- UChoose (NCT02404038)
- Testing
- Nur-Isterate, Nuvaring, Triphasil
- Where
- South Africa
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Desmond Tutu HIV Centre
Food Acceptance, Soy Milk
Acceptability of Soy Milk as a Calcium-Rich Beverage in School Children in New York City Public Schools
NYC Public Schools is testing offering soy milk alongside dairy milk on the lunch line for all students during the month of May at select school sites to understand: Whether students choose and drink soy milk Whether offering soy…
- Conditions
- Food Acceptance, Soy Milk, Schools, New York
- Trial name
- NCT07595562
- Testing
- Acceptability of soy milk
- Where
- 6 sites in United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Physicians Committee for Responsible Medicine
Bone Sarcoma, Embryonal Rhabdomyosarcoma
Chemo-immunotherapy in Patients Under 18 Years of Age With Bone and Soft Tissue Sarcomas
Data from 40 patients are planned to be included in the study to randomize approximately 10 patients. This study involves patients with advanced/metastatic GD2-positive rhabdomyosarcoma after progression on 1st line of…
- Conditions
- Bone Sarcoma, Embryonal Rhabdomyosarcoma, Alveolar Rhabdomyosarcoma
- Trial name
- FollowTheDIN (NCT06669013)
- Testing
- dinutuximab beta
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- N.N. Petrov National Medical Research Center of Oncology
Schizophrenia, Bipolar Disorder
Physician Survey on Monitoring of Patients Treated With Quetiapine
A physician survey to document receipt of metabolic educational materials and assess behavior of physicians in following messages communicated through the educational materials
- Conditions
- Schizophrenia, Bipolar Disorder, Major Depressive Disorder
- Trial name
- NCT01795326
- Volunteers
- 800 people
- Sponsor
- AstraZeneca
Advanced Malignant Solid Neoplasm, Ann Arbor Stage III Non-Hodgkin Lymphoma
Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)
This phase II Pediatric MATCH trial studies how well samotolisib works in treating patients with solid tumors, non-Hodgkin lymphoma, or histiocytic disorders with TSC or PI3K/MTOR mutations that have spread to other places in the…
- Conditions
- Advanced Malignant Solid Neoplasm, Ann Arbor Stage III Non-Hodgkin Lymphoma, Ann Arbor Stage IV Non-Hodgkin Lymphoma, Malignant Glioma
- Trial name
- NCT03213678
- Testing
- Biospecimen Collection, Computed Tomography, FDG-Positron Emission Tomography
- Where
- 127 sites in United States, Puerto Rico
- Volunteers
- 18 people
- Sponsor
- National Cancer Institute (NCI)
Sleep, Food Habits
Sleep Duration and Quality in Children
Obesity in children is a priority of public health initiatives, and reliable obesity prevalence and severity assessments are needed for policy decisions and study directions.
- Conditions
- Sleep, Food Habits, Lifestyle Factors
- Trial name
- Sleep-FAST (NCT05652829)
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Alcohol Use, Smoking
Choices-Teen: A Bundled Risk Reduction Intervention for Juvenile Justice Females
This pilot study will: 1) demonstrate the feasibility of delivering CHOICES-TEEN with master's level mental health professionals within a juvenile justice setting; 2) determine acceptance of CHOICES-TEEN as measured by client…
- Conditions
- Alcohol Use, Smoking, Contraception, HIV
- Trial name
- NCT02252471
- Testing
- Choices-Teen
- Volunteers
- 28 people
- Sponsor
- University of Houston
Delay in Sexual Debut Among Adolescents, Knowledge About Condom Use
Parenting Styles and Parent-Offspring Communication on Sexuality Issues
The main objective of the study was to develop a novel intervention method which could reduce the spread of Sexually Transmitted Infections (including HIV) and unwanted pregnancies by improving parent-child communication using…
- Conditions
- Delay in Sexual Debut Among Adolescents, Knowledge About Condom Use, Parent-child Communication, Frequency and Quality
- Trial name
- PREPARE (NCT01772628)
- Testing
- Classroom-based component, STI/HIV prevention education, Homework assignment component
- Where
- Uganda
- Volunteers
- 1,700 people
- Sponsor
- Child Health & Development Centre
Alcohol Abuse, Drug Abuse
Adolescent Family-Based Alcohol Prevention
This study explores whether giving families a choice of family-based prevention programs to prevent adolescent alcohol use will make a difference in program recruitment, retention, completion, as well as adolescent outcomes.
- Trial name
- NCT00858065
- Testing
- Strengthening Families Program (SFP), Family Matters
- Where
- 2 sites in United States
- Volunteers
- 1,228 people, healthy volunteers welcome
- Sponsor
- Pacific Institute for Research and Evaluation
Complicated Urinary Tract Infection, Infection
Single Dose Intravenous Antibiotics for Complicated Urinary Tract Infections in Children
Urinary tract infections (UTI) are commonly encountered in children, with 7% diagnosed with at least one UTI by the age of 19 years.
- Conditions
- Complicated Urinary Tract Infection, Infection, Pediatric Infectious Disease
- Trial name
- CHOICE UTI (NCT04876131)
- Testing
- Benzylpenicillin - single dose, Benzylpenicillin - three days, Gentamicin - single dose
- Where
- 7 sites in Australia, New Zealand
- Volunteers
- 396 people
- Sponsor
- Murdoch Childrens Research Institute
HIV Infections
Integrating Supports to Promote PrEP for Black Adolescents Working With Apps- Atlanta
This study applies Social Cognitive Theory to develop behavioral interventions promoting PrEP adherence. It seeks to adapt and test the enhanced HMP app for feasibility and acceptability among Black adolescents and young adults…
- Trial name
- NCT07535346
- Testing
- Health MPowerment App
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Emory University