Clinical trials: Cigarette Smoking Behavior
Vaping, Adolescent
Nicotine and Cannabis Vape Labeling Experiment - Spring 2025
This study assesses how the ways in which nicotine and cannabis vaping devices are labeled impact use susceptibility, anticipated effects, and health harm.
- Conditions
- Vaping, Adolescent, Electronic Cigarette Use, Nicotine
- Trial name
- EPIC/ADVANCE (NCT06919276)
- Testing
- Vaping Device Labeling
- Where
- United States
- Volunteers
- 3,048 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Vaping
Graphic Messages to Prevent E-Cigarette Use Among Black and Latino Adolescents
The aim of this study is to determine if graphic messages prevent future vaping use among African American and Latino adolescents.
- Trial name
- NCT04899999
- Testing
- Financial reward graphic message, Health reward graphic message, Self-efficacy graphic message
- Where
- United States
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- University of Rochester
E-cigarette Use, Substance Use
The Development and Evaluation of a Culturally Grounded ENDS Intervention for Rural Hawaiian Youth
The purpose of this research proposal is to develop and evaluate a culturally grounded, ENDS prevention intervention for rural Hawaiian youth. This will be accomplished through two specific aims.
- Trial name
- NCT06929520
- Testing
- ENDS Prevention Intervention (TBD)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Smoking, Smoking Cessation
Comparison of Four Different Smoking Cessation Programmes
The primary objective of the study is to compare the efficacy of four different smoking cessation programmes, including a proactive telephone counseling intervention, a reactive telephone counseling a and an interactive web-based…
- Conditions
- Smoking, Smoking Cessation, Self-efficacy
- Trial name
- Fristart (NCT01487642)
- Testing
- Standard 15-minute telephone counselling, Proactive telephone counselling, Interactive web-based smoking cessation programme
- Where
- Denmark
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Schizophrenia
Imaging of Brain Receptors in Healthy Volunteers and in Patients With Schizophrenia
This study will use single photon emission computed tomography (SPECT) to study brain nicotine receptors (proteins on the surface of brain cells) in healthy subjects and in patients with schizophrenia.
- Trial name
- NCT00061789
- Testing
- SPECT Imaging of Nicotinic Acetylcholine Receptors in Brain
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Cannabis, Vaping
A Virtual Reality Game to Prevent E-cigarette and Cannabis Vaping
The goal of this study is to develop and test an adapted version of our virtual reality videogame intervention prototype, Invite Only VR, developed for middle school students, which focuses on e-cigarette and marijuana vaping…
- Conditions
- Cannabis, Vaping, Emotion Regulation
- Trial name
- NCT07413432
- Testing
- Virtual reality videogame intervention for vaping prevention
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Yale University
Secondhand Exposure to Electronic Cigarette
Bystanders' Exposure to Electronic Cigarette Aerosol in Confined Settings
Objective of this study is to investigate the bystanders' exposure to e-cigarette emissions in controlled conditions in confined settings. Design: a cross-sectional experimental study developed in two settings: a car and a room.
- Trial name
- NCT04140617
- Testing
- Exposure to aerosol of electronic cigarette
- Where
- Spain
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Institut Català d'Oncologia
Smoking
Electronic Cigarette Use and Quitting in Youth
A mixed method (longitudinal, trajectory and qualitative studies) to provide comprehensive evidence on the impact of e-cigarette use on smoking and quitting among smoking youth in Hong Kong.
- Trial name
- NCT02949648
- Testing
- Electronic cigarette
- Where
- Hong Kong
- Volunteers
- 189 people
- Sponsor
- The University of Hong Kong
Tobacco Use Cessation, Tobacco Use Disorder
Effectiveness of Bupropion for Treating Nicotine Dependence in Young People
Little is known about the best ways to help young people stop smoking. Bupropion (a medication marketed as Wellbutrin or Zyban) has proved helpful in treating adult smokers.
- Trial name
- NCT00129272
- Testing
- Bupropion-SR
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Nicotine Dependence, Cigarettes, Cessation, Tobacco
Reducing Nicotine Addiction in Adolescent Smokers
Adolescents are at risk for tobacco use due to factors such as impulsivity, poor perception, desire to prove themselves, and insufficient neurological development.
- Conditions
- Nicotine Dependence, Cigarettes, Cessation, Tobacco, Cessation, Smoking, Adolescent Problem Behavior
- Trial name
- NCT05477342
- Testing
- Board Game, Tobacco Cesseation Education, Combined İntervention
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Ministry of National Education, Turkey
Cigarette Smoking Behavior
Effects of Contingency Management and Nicotine Replacement Therapy on Youth Smoking
Cigarette smoking is an important public health concern, and it is most often initiated in adolescence. Despite substantial research on smoking cessation in adults, however, relatively little effort has focused on therapeutic…
- Trial name
- NCT01359709
- Testing
- Nicotine polacrilex
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Smoking Cessation Intervention, Smoking Abstinence
Boosting Chinese Healthcare Service Providers' Utilization of Smoking Cessation Interventions by 'WeChat WeQuit' Program
In this single-blind, randomized trial, undertaken in China with 8-week interventions and follow-up to 52 weeks, about 2,200 providers will be randomly allocated to the intervention or control group.
- Trial name
- NCT03556774
- Testing
- 'WeChat WeQuit' smoking cessation training program
- Where
- China
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
E-Cig Use, Vaping
A Virtual Reality Videogame for E-cigarette Prevention in Teens
The use of the Invite Only VR, with the aim to prevent the initiation of e-cigarette use in teens by increasing their knowledge, decreasing their intentions to use e-cigarettes, influencing their harm perceptions and attitudes…
- Trial name
- NCT04054765
- Testing
- videogame, treatment as usual
- Where
- United States
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- Yale University
E Cigarette Use
Novel Pulmonary Imaging of Lung Structure and Function in E-cigarette Smokers
This is a longitudinal study of the long-term health impact of e-cigarette smoking on the lungs. Participants will be followed over a period of 5 years, and impacts of e-cigarette smoking on the lungs will be measured with…
- Trial name
- NCT04616313
- Testing
- Hyperpolarized Xenon-129 MRI of the lungs, Computed Tomography (CT), Pulmonary Function Tests (PFT)
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Cigarette Smoking, Nicotine Dependence
School Nurse-Delivered Smoking Cessation Intervention
The purpose of this study is to conduct a randomized controlled school-based trial to evaluate the effectiveness of a four-session school nurse-delivered smoking cessation intervention in increasing abstinence rates among high…
- Trial name
- NCT00682474
- Testing
- Counseling Intervention, Information Intervention
- Where
- United States
- Volunteers
- 1,058 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Smoking, Smoking Behaviors
Smoking Prevention Program in Poland
Smoking Prevention Program is a pilot exploratory study with a standardized curriculum based on the Tobacco Prevention Toolkit from Stanford University and translated into Polish by the members of Students Scientific Association…
- Conditions
- Smoking, Smoking Behaviors, Smoking (Tobacco) Addiction, E-cigarette Use
- Trial name
- NCT05488743
- Testing
- educational intervention
- Where
- Poland
- Volunteers
- 180 people
- Sponsor
- Wroclaw Medical University
Cigarette Smoking-Related Carcinoma
Electronic Cigarette Use During Pregnancy
Aim 1: To compare the overall toxicant exposure in pregnant women who use electronic cigarettes (e-cigs, vapor, e-liquid, e-juice, vape, vaping devices) compared to women who smoke conventional cigarettes. Aim 2.
- Trial name
- NCT03480373
- Where
- 6 sites in United States
- Volunteers
- 182 people
- Sponsor
- UConn Health
Tobacco Smoking
Trial Comparing Different Methods of Support With Stopping Smoking (PORTSSS/Stop Together Trial)
This study shall determine whether or not proactive telephone support for smoking cessation delivered to quitline callers is more effective than standard 'reactive' provision and whether or not the offer of a voucher for a cost…
- Trial name
- PORTSSS (NCT00775944)
- Testing
- Proactive telephone support, Reactive (standard) telephone support, Offer of voucher for cost-free Nicotine Replacement Therapy
- Where
- United Kingdom
- Volunteers
- 2,591 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Vaping
Influencer Marketing: a Survey-based Experiment Among Adolescents
Adolescents (N = 664) participated in the online survey-based experiment. They were randomly shown 10 videos, featuring influencers promoting e-cigarettes alongside healthy lifestyle activities (experimental group), or…
- Trial name
- NCT06501937
- Testing
- Influencer marketing
- Where
- United States
- Volunteers
- 664 people
- Sponsor
- University of Southern California
Electronic Nicotine Delivery Systems
Influencer E-Cigarette and Cannabis Marketing: a Survey-Based Experiment Among Adolescents
Adolescent non-users of e-cigarettes and cannabis (N = 1,462) participated in the in-class survey-based experiment. They were randomly shown 3 pairs of images featuring influencers promoting e-cigarettes alongside cannabis…
- Trial name
- NCT06919263
- Testing
- Influencer marketing
- Where
- United States
- Volunteers
- 1,462 people
- Sponsor
- University of Southern California