Clinical trials: Consciousness
Consciousness Disorders
Transcranial Alternating Current Stimulation in Patients With Disorders of Consciousness
In recent years, many literatures have reported that tACS, as a non-invasive electrical brain stimulation technique, has been applied in depression, schizophrenia, dementia and other fields.
- Trial name
- NCT06211439
- Testing
- real transcranial alternating current stimulation
- Where
- China
- Volunteers
- 64 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Gender Issues
Gender Stigma Consciousness and Surgical Training
Previous investigations have focused on challenges that surgeons face once they have entered into practice. We have yet to explore difficulties in the training environment, and whether these have an effect on professional…
- Trial name
- NCT03623009
- Testing
- An article meant to trigger certain psychosocial behaviors, a neutral article
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Dental Caries, Child Behavior
Efficacy of Moderate Sedation for Dental Treatment of Young Children
There is lack of clinical trials on pediatric dental sedation. The purpose of this study is to test (using a randomized controlled trial design) the hypothesis that young children behavior during dental treatment improves with…
- Conditions
- Dental Caries, Child Behavior, Conscious Sedation Failure During Procedure
- Trial name
- NCT00902395
- Testing
- Midazolam, Protective stabilization, Midazolam, ketamine
- Where
- Brazil
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Syncope, Chest Pain
Autonomic Monitoring in Neurocardiogenic Syncope
This is a prospective observational pilot study of suitability of autonomic monitoring via the VU-AMS device for prediction of neurocardiogenic syncope (NCS) in children referred to cardiopulmonary exercise testing (CPET) for a…
- Conditions
- Syncope, Chest Pain, Dyspnea
- Trial name
- ANSS (NCT05907018)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
COVID-19 Pandemic
The Combined Usage of Clinical Physical Finding in Management of COVID 19 Patients
Physiological indicators such as blood pressure, heart rate, respiratory rate, and consciousness status of COVID-19 patients are used to apply the START (simple triage and rapid treatment, START), Modified Early Warning Score…
- Trial name
- NCT06528119
- Testing
- COVID 19 pandemic
- Where
- Taiwan
- Volunteers
- 10,000 people
- Sponsor
- St. Martin De Porress Hospital
Disorders of Consciousness
Investigation of Mnesic Capacities in Patients With a Disorder of Consciousness
Following severe brain damage, some individuals lose partial or total awareness of themselves and their environment, falling into a coma that can evolve towards a Disorder of Consciousness (DoC).
- Trial name
- MemoDoC (NCT06959212)
- Testing
- Physiological recordings, Semi-structured interviews, Psychological scales
- Where
- 2 sites in France
- Volunteers
- 175 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Blood Donors
Addressing Fear and Risk of Vasovagal Reactions Among High School Donors
In this study, high school donors will be asked about their blood donation-related fears prior to their donation. Half of the donors reporting fear will be assigned to a brief coping skills intervention.
- Trial name
- NCT03835299
- Testing
- Fear Intervention
- Where
- United States
- Volunteers
- 4,035 people
- Sponsor
- Ohio University
Vegetative State, Minimally Conscious State
Multichannel tDCS to Reduce Hypertonia in Patients With Prolonged DOC
Previous studies showed that transcranial direct current stimulation (tDCS) transiently improves performance of motor function in stroke patients, as well as decrease muscle hypertonia.
- Conditions
- Vegetative State, Minimally Conscious State, Spasticity, Muscle, Disorder of Consciousness
- Trial name
- NCT03797573
- Testing
- tDCS
- Where
- Belgium
- Volunteers
- 17 people
- Sponsor
- University of Liege
Syncope, Vasovagal
Cardioneuroablation and Ventricular Proarrhythmia
Cardioneuroablation (CNA) is a promising tool to treat patients with asystolic reflex syncope. CNA acts through complete or near complete abolition of vagal nerve chronotropic and dromotropic effects on the heart, resulting in…
- Trial name
- Roman4 (NCT06458140)
- Testing
- Cardioneuroablation
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Centre of Postgraduate Medical Education
Syncope, Vasovagal
Presyncope (Syncope) Prevention Study
This study was a prospective, randomized clinical trial that was conducted in adolescents (10 through 14 years of age) receiving at least one recommended intramuscularly administered vaccine to evaluate the efficacy and…
- Trial name
- PS^2 (NCT04772755)
- Testing
- Buzzy® and Electronic Game
- Where
- 2 sites in United States
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- Duke University
Ischemic Stroke, Hemorrhagic Shock
Predictors Of Stroke Outcome In Chidren
Stroke can be defined as an abrupt loss of brain function that is caused by decreased cerebral blood flow. Stroke can occur at all stages of life, but presentation is variable depending on age, involved artery, and underlying…
- Trial name
- NCT04331457
- Testing
- Brain magnetic resonance imaging (MRI) , computed tomography (CT)
- Volunteers
- 30 people
- Sponsor
- Assiut University
Anxiety, Low Mood
Effectiveness of a School Wellbeing Programme for Internalising Problems in Irish Primary School Children
The aim of this study is to assess the effectiveness of a school-based multi-component universal programme for the reduction of internalising problems (i.e. anxiety and low mood) in primary school pupils.
- Trial name
- NCT05061381
- Testing
- A Lust for Life Schools Programme
- Where
- Ireland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Attention Skills, Mindfulness
Effects of a Mindfulness-Based Education Program on Preschool Children's Attention Skills
This study examined the effect of the Mindfulness Education Programme on the attention levels of preschool children aged 60-72 months.
- Conditions
- Attention Skills, Mindfulness, Early Childhood Education
- Trial name
- NCT07617129
- Testing
- Mindfulness Education Programme
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Inonu University
Patients in Minimally Conscious State After a Severe Brain Injury
tDCS on Precuneus in MCS: Repeated Stimulations
In this study researchers will apply transcranial direct current stimulation (tDCS) for 5 consecutive days in chronic patients in minimally conscious state (MCS).
- Trial name
- NCT02702362
- Testing
- transcranial direct current stimulation
- Volunteers
- 33 people
- Sponsor
- Hangzhou Normal University
Brain Death
Thyroxine Replacement in Organ Donors
To compare oral versus intravenous administration of thyroid hormone: 1) for reversibility of hemodynamic instability in organ donors, and, 2) the pharmacokinetics of oral vs iv thyroid administration
- Trial name
- NCT00238030
- Testing
- L-thryoxine, iv thryoxine
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Disorder of Consciousness, Minimally Conscious State
Simultaneously PET/MRI in Prolonged DOC Patients
Recently introduced hybrid PET/MR scanners provide the opportunity to measure simultaneously, and in direct spatial correspondence, both metabolic demand and functional activity of the brain, hence capturing complementary…
- Conditions
- Disorder of Consciousness, Minimally Conscious State, FDG-PET, Rs-fMRI
- Trial name
- NCT04164680
- Testing
- Multimodal Neuroimaging
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hangzhou Normal University
Syncope
Multi-Site Near Infrared Spectroscopy (NIRS) Monitoring of Children During Tilt Table Testing
PURPOSE OF THE STUDY This study will explore the use of multi-site NIRS monitoring during tilt table testing, combining somatic and cerebral saturations data with hemodynamic data to establish the non-invasive assessment of…
- Trial name
- NIRS & Tilt (NCT00659464)
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Autism Spectrum Disorder
Psycho-educational Program to Enhance Alerting Consciousness and Seeking Support Among Family Caregivers Having Children With Autism
The goal of this study is to evaluate the effect of a psycho-educational program to enhance alert consciousness and seeking support among family caregivers having children with autism.
- Trial name
- NCT07604532
- Testing
- Psycho-educational Program
- Where
- 2 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Behavior, Child, Neurocognition, Child
Community-Based Conscious Discipline Program in Grenada
To improve neurocognitive outcomes in 2-year-old children by implementing a community-based intervention program that follows the principles of Conscious Discipline.
- Conditions
- Behavior, Child, Neurocognition, Child, Development, Child
- Trial name
- NCT04697134
- Testing
- Conscious Discipline-Based Environmental Enrichment Intervention
- Where
- Grenada
- Volunteers
- 333 people, healthy volunteers welcome
- Sponsor
- Windward Islands Research and Education Foundation
Brain Death, Organ Donation
Goal of Open Lung Ventilation in Donors
The primary goal of this study is to assess whether ventilation of deceased organ donors with an open lung protective ventilatory strategy will improve donor lung utilization rates and donor oxygenation compared to a conventional…
- Conditions
- Brain Death, Organ Donation, Organ Transplant Failure or Rejection
- Trial name
- GOLD (NCT03439995)
- Testing
- Open lung protective ventilation, Conventional ventilation
- Where
- 4 sites in United States
- Volunteers
- 154 people
- Sponsor
- Vanderbilt University Medical Center