Clinical trials: Coronary Artery Chronic Total Occlusion
Chronic Total Occlusion of Coronary Artery
CrossBoss and Hybrid Registry on Coronary Chronic Total Occlusions
The successful re-opening of a blocked coronary artery has a beneficial effect on the further clinical course (e.g. improvement of clinical symptoms, improved quality of life, increased heart function, etc.).
- Trial name
- RECHARGE (NCT02075372)
- Testing
- Data registration
- Where
- 21 sites in Belgium, France and 2 more
- Volunteers
- 1,177 people
- Sponsor
- Hasselt University
Coronary Artery Disease (CAD), Chronic Total Occlusion of Coronary Artery
Predictors and Long-term Incidence of In-stent Restenosis After Chronic Total Occlusion Percutaneous Coronary Intervention
The goal of this clinical trial is to describe the long-term (≥ 3 years) patency of coronary artery stents following chronic total occlusion percutaneous coronary intervention (CTO PCI).
- Conditions
- Coronary Artery Disease (CAD), Chronic Total Occlusion of Coronary Artery, Chronic Total Occlusion (CTO)
- Trial name
- NCT07473596
- Testing
- chronic total occlusion percutaneous coronary intervention (CTO PCI), coronary computed tomography angiography, invasive coronary angiography
- Where
- Finland
- Volunteers
- 294 people
- Sponsor
- Lauri Mansikkaniemi
Angina Pectoris, Coronary Artery Disease
Chronic Total Coronary Occlusion Treatment Results 6 Years After Bioresorbable Scaffold Implantation
Aim of the study is to evaluate chronic total coronary occlusion treatment results 6 years after bioresorbable scaffold implantation by quantitative coronary analysis, intravascular ultrasound and optical coherence tomography.
- Conditions
- Angina Pectoris, Coronary Artery Disease, Occlusion, Coronary
- Trial name
- CTO_BVS (NCT06164977)
- Testing
- Percutaneous coronary intervention.
- Where
- Latvia
- Volunteers
- 34 people
- Sponsor
- Pauls Stradins Clinical University Hospital
Chronic Total Occlusion of Coronary Artery
Application of Coronary Artery Chronic Total Occlusion Scoring Systems
Studying the prediction ability of different CTO scoring systems on Asian CTO PCI population with their relation to technical success and developing a newer stepwise approach depending on these CTO scoring systems for choosing…
- Trial name
- CTO-PCI (NCT05883579)
- Testing
- percutaneous coronary intervention
- Where
- Taiwan
- Volunteers
- 650 people
- Sponsor
- Assiut University
Coronary Artery Disease, Chronic Total Occlusions
Prognostic Impact of Chronic Total Occlusions
The purpose of this study is to determine the prognostic impact of the presence of chronic total occlusions (CTO) of the coronary arteries in patients undergoing coronary angiography and PCI.
- Trial name
- NCT02084888
- Where
- Sweden
- Volunteers
- 91,154 people
- Sponsor
- Sahlgrenska University Hospital
Coronary Artery Disease
Drug-Coated Balloon Versus Drug-eluting Stent Angioplasty for Treatment of Chronic Total Occlusion - The DCB-CTO Trial
Chronic total occlusion (CTO) remains one of the most challenging lesions in coronary artery disease management. Percutaneous coronary intervention using drug-eluting stents is currently a standard treatment approach; however…
- Trial name
- DCB-CTO (NCT07369765)
- Testing
- Drug-Eluting Stent Group, Drug Coated Balloon Group
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Biruni University
Coronary Artery Disease (CAD), Chronic Total Occlusion (CTO)
AGECTO Study: PCI vs. Optimal Medical Therapy for CTO in the Octogenarian Patients
The study compares an interventional strategy (PCI) with optimal medical therapy (OMT) in ultra-octogenarians with chronic total occlusions (CTO).
- Conditions
- Coronary Artery Disease (CAD), Chronic Total Occlusion (CTO), Percutaneous Coronary Intervention (PCI), Optimal Medical Therapy
- Trial name
- AGECTO (NCT07442526)
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- San Luigi Gonzaga Hospital
Chronic Total Occlusion of Coronary Artery
Early and Midterm Outcomes of Intravascular Ultrasound (IVUS) Versus Non-IVUS Guidance in Complex Coronary Chronic Total Occlusion (CTO) Revascularization.
Various CTO percutaneous coronary intervention (PCI) studies defined CTO as as a substantial atherosclerotic blockage with >3 months duration of TIMI (Thrombolysis in Myocardial Infarction) 0 flow other than via collaterals.
- Trial name
- NCT04917432
- Testing
- intravascular ultrasound (IVUS), Conventional CTO PCI (non-IVUS guided)
- Volunteers
- 70 people
- Sponsor
- Assiut University
Coronary Artery Disease, Chronic Total Occlusion of Coronary Artery
Evaluation of Long Coronary Artery Stents With Third-generation Dual-source Computed Tomography Angiography
The goal of this clinical trial is to assess third-generation dual-source coronary computed tomography angiography (CCTA) performance in the evaluation of long coronary stents in patients with coronary artery chronic total…
- Trial name
- NCT06543641
- Testing
- Coronary computed tomography angiography, Invasive coronary angiography
- Where
- Finland
- Volunteers
- 45 people
- Sponsor
- Lauri Mansikkaniemi
Coronary Artery Disease
Prospective Global Registry for the Study of Chronic Total Occlusion Intervention
Percutaneous coronary intervention (PCI) of chronic total occlusions (CTOs) is increasingly being performed in patients with advanced coronary artery disease, but there is limited information on the techniques utilized and the…
- Trial name
- PROGRESS-CTO (NCT02061436)
- Where
- 48 sites in United States, Canada and 4 more
- Volunteers
- 2,000 people
- Sponsor
- Minneapolis Heart Institute Foundation
Coronary Artery Disease, Chronic Total Occlusion
German Epicardial Collateral CTO Registry
The EPIC registry is an observational multicentre registry evaluating the technical feasibility of retrograde CTO-PCI using epicardial collateral connections.
- Conditions
- Coronary Artery Disease, Chronic Total Occlusion, Percutaneous Coronary Intervention
- Trial name
- EPIC (NCT04533633)
- Testing
- Retrograde Percutaneous Coronary Intervention of Chronic Total Occlusion
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- Universitätsmedizin Mannheim