Clinical trials: Coronary Embolism
Atrial Fibrillation, Thrombosis
Association of Genetic Polymorphisms With Atrial Fibrosis and Thrombogenic Substrate in Patients With Non-valvular Atrial Fibrillation
Atrial fibrillation (AF) is the most frequently encountered cardiac arrhythmia. Emerging data suggests that common genetic variants are associated with the development of AF.
- Conditions
- Atrial Fibrillation, Thrombosis, Stroke, Genetic Predisposition
- Trial name
- ANATOLI-AF (NCT03560219)
- Testing
- Biomarkers, Cardiac Magnetic Resonance Imaging, Echocardiography, Flow Mediated Dilatation, Genetic Analysis
- Volunteers
- 225 people
- Sponsor
- Memorial Ankara Hospital
Coronary Thrombosis
In-hospital Clinical Outcome of Deferred Stenting Versus Immediate Stenting in the Management of Acute STEMI Presenting With High Thrombus Burden.
To compare the in hospital clinical outcomes in terms of efficacy and safety of deferred stenting versus non-deferred stenting in STEMI patients with high thrombus burden undergoing primary percutaneous intervention.
- Trial name
- NCT05647018
- Testing
- Primary Percutaneous coronary angiography
- Volunteers
- 440 people
- Sponsor
- Assiut University
Blood Clots, Infection and Inflammatory Reaction
Cobas® Lumira Collection of Venous and Capillary Blood Samples for the Research, Optimization and Calibration of New Diagnostic Devices
This study is a blood sample collection study, collecting venous and capillary blood samples from adult patients in the UK, with a range of health conditions.
- Conditions
- Blood Clots, Infection and Inflammatory Reaction, Heart Disease, Kidney Disease
- Trial name
- EVOLVE (NCT07378514)
- Testing
- Blood samples are obtained and pseudonymized, prior to use for the development, optimization and calibration of diagnostic tests
- Volunteers
- 30,000 people
- Sponsor
- LumiraDx UK Limited
Cardiovascular Diseases, Coronary Disease
Lupus Cohort--Thrombotic Events and Coronary Artery Disease
To study longitudinally the incidence, pathogenesis, and risk factors for thrombotic events and coronary artery disease in a cohort of patients with systemic lupus erythematosus (SLE).
- Conditions
- Cardiovascular Diseases, Coronary Disease, Thrombosis, Heart Diseases
- Trial name
- NCT00005436
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Congenital Heart Disease, Single-ventricle
Extracellular Vesicle Micro RNA Profiling in Congenital Heart Disease: Fetal-Maternal Regulation in Neonatal Thrombosis
Newborns with congenital heart disease (CHD) are at increased risk of developing postpartum and postoperative blood clots after cardiac surgery.
- Conditions
- Congenital Heart Disease, Single-ventricle, Thrombosis
- Trial name
- EVmiRNA (NCT06434207)
- Testing
- Collecting discarded blood samples
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Boston Children's Hospital
Cardiovascular Diseases, Carotid Artery Diseases
Mechanisms Underlying Psychosocial Associations With Ischemic Heart Disease (Kuopio)
To examine the relationships among psychosocial factors and carotid atherosclerosis, myocardial ischemia, arrhythmias, and thrombosis.
- Conditions
- Cardiovascular Diseases, Carotid Artery Diseases, Arrhythmia, Myocardial Ischemia
- Trial name
- NCT00005260
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Coronary Artery Disease
Assessment of Distal Protection Device in Patients at High Risk for Distal Embolism in Acute Coronary Syndrome (ACS)
Attenuated plaque ≥ 5mm by intravascular ultrasound(IVUS) was reported to be high risk for distal embolism in Acute coronary syndrome(ACS).
- Trial name
- VAMPIRE3 (NCT01460966)
- Testing
- Filtrap™ + Thrombus aspiration catheter, Thrombus aspiration catheter
- Where
- Japan
- Volunteers
- 200 people
- Sponsor
- Yokohama City University Medical Center
Coronary Occlusion/Thrombosis, Peptic Ulcer Hemorrhage
Systematic Screening for Risk-factors for Ulcer Bleeding Before Anti-thrombotic Treatment
In a prospective randomised study design to investigate, if a systematic risk factor screening for bleeding ulcer in patients, who following percutaneous coronary intervention (PCI) commence a one year combination treatment with…
- Trial name
- NCT01447498
- Testing
- Screening for risk factors for ulcer bleeding
- Where
- Denmark
- Volunteers
- 2,024 people
- Sponsor
- Odense University Hospital
Cardiopulmonary Bypass, Congenital Defects
Aprotinin in Neonates Undergoing Cardiopulmonary Bypass
This is a retrospective chart review study. The purpose of this study is to review our experience at Children's Healthcare of Atlanta in neonates receiving aprotinin.
- Conditions
- Cardiopulmonary Bypass, Congenital Defects, Hemostasis
- Trial name
- NCT00469742
- Where
- United States
- Volunteers
- 290 people
- Sponsor
- Children's Healthcare of Atlanta
Patent Foramen Ovale, Stroke
PFO ACCESS Registry
Closure of Patent Foramen Ovale with the AMPLATZER® PFO OCCLUDER in patients with at least two cryptogenic strokes due to presumed paradoxical embolism through a patent foramen ovale and who have failed conventional therapy.
- Trial name
- NCT00583401
- Testing
- Device closure with the AMPLATZER PFO Occluder
- Sponsor
- Abbott Medical Devices
Atherosclerosis of Coronary Artery, Cardiovascular Disease
Radiation Dose From Computed Tomography Before and After Implementation of a High Pitch Dual Spiral Technique
The purpose of this study is to compare the radiation exposure of a variety of chest CT examinations performed on the current state of the art CT scanners (64 slice, dual source CT scanner) with the radiation exposure for…
- Conditions
- Atherosclerosis of Coronary Artery, Cardiovascular Disease, Pulmonary Embolism, Aortic Aneurysm Without Mention of Rupture Nos
- Trial name
- FLASH (NCT01111760)
- Where
- United States
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Michael Gallagher
Congenital Heart Disease, Unfractionated Heparin
Comparison of the Best Method for Measuring Anti-Xa Activity in Children Receiving Unfractionated Heparin in Cardiac Intensive Care (COMPAXE-HNF)
This study aims to compare the accuracy of two different blood sampling methods from a central venous catheter (CVC) for measuring anti-Xa activity in children receiving unfractionated heparin (UFH) from this CVC.
- Conditions
- Congenital Heart Disease, Unfractionated Heparin, Anti Xa Activity
- Trial name
- COMPAXE-HNF (NCT07365670)
- Testing
- blood sampling for measuring anti-Xa activity, measurement of anti-XA activity
- Volunteers
- 22 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Other Acute Illnesses Presenting to the Hospital, Heart Failure
Evaluation of Implementation of a National Point-of-Care Ultrasound Training Program
This VA QUERI Partnered Evaluation Initiative will evaluate the impact of an immersive Point-of-care Ultrasound (POCUS) Training Course on provider skill acquisition and retention; the frequency of POCUS use by trained providers…
- Conditions
- Other Acute Illnesses Presenting to the Hospital, Heart Failure, Pneumonia, Deep Venous Thrombosis
- Trial name
- NCT03296280
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Contraception, Female Contraception
A Postmarketing Study of the Risk of Venous Thromboembolism (Blood Clots), Myocardial Infarction (Heart Attacks), and Stroke Among Women Using ORTHO EVRA (Norelgestromin and Ethinyl Estradiol Contraceptive Patch) Compared With Women Who Take Oral Contraceptives for Birth Control
The purpose of the study is to use data from a health care information database to assess the risk of venous thromboembolism (blood clots), myocardial infarction (heart attacks), and stroke among women using a transdermal…
- Trial name
- NCT00377988
- Testing
- Transdermal Contraceptive System, Norgestimate-containing oral contraceptives with EE
- Volunteers
- 423 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Cardiac Valve Disease
Ultrafiltration on Coagulation Function in Cardiac Surgery
To determine the effect of modified ultrafiltration, which is usually employed for reducing free water at the end of cardiopulmonary bypass (CPB), on coagulation profile in patients undergoing cardiac surgery
- Trial name
- NCT04031144
- Testing
- Ultrafiltration
- Where
- South Korea
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
On-pump Cardiac Surgery - Prevention - Intervention - Experimental Group - Control Group - Incidence - Complications, DVT - Deep Vein Thrombosis
This Research Proposal Focuses on Evaluating the Effectiveness of a Nursing Care Protocol in Preventing Deep Vein Thrombosis (DVT) in Patients Undergoing On-pump Cardiac Surgery. The Study Will Include an Intervention Group That Receives the Nursing Protocol and a Control Group That Receives Routine
The primary focus of this research proposal is to examine the efficacy of a nursing care protocol in preventing the occurrence of deep vein thrombosis (DVT) in patients undergoing on-pump cardiac surgery.
- Conditions
- On-pump Cardiac Surgery - Prevention - Intervention - Experimental Group - Control Group - Incidence - Complications, DVT - Deep Vein Thrombosis, DVT Prophylaxis, DVT Prevention
- Trial name
- DVT (NCT07347652)
- Testing
- IPC devices facilitate venous return by simulating the physiological effects of muscle contraction, reducing venous stasis.
- Where
- Cyprus
- Volunteers
- 67 people
- Sponsor
- Near East University, Turkey
Primary Ovarian Insufficiency, Cardiovascular Diseases
Associations of Combinations of Single-nucleotide Polymorphisms in Women With Premature Ovarian Failure
Research objective. To study the associations between combinations of single nucleotide polymorphisms and behavioural risk factors with non-communicable diseases and adverse outcomes in women with premature ovarian failure.
- Conditions
- Primary Ovarian Insufficiency, Cardiovascular Diseases, Menopause, Premature, Coronary Disease
- Trial name
- NCT04943354
- Testing
- Taking a person's venous blood
- Where
- Russia
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Ryazan State Medical University
Arrhythmia, Acute Kidney Injuries
This is an Observational Study That Aims to Demonstrate Postoperative Risk Factors in Pediatric Cardiac Surgery
This retrospective observational study aims to identify risk factors for postoperative complications in children undergoing cardiac surgery at a tertiary hospital in Brazil.
- Conditions
- Arrhythmia, Acute Kidney Injuries, Sepsis, Pneumopathy
- Trial name
- PEDS-CARE (NCT06985082)
- Testing
- THERE IS NOT A INTERVENTION
- Volunteers
- 310 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Diabetes Mellitus, Hypertension
Evidence-based Laboratory Test Order Sets in Primary Care
Cluster randomised controlled trial to evaluate what the effect is of evidence-based order sets aimed at five indications on the appropriateness of laboratory test ordering in primary care.
- Conditions
- Diabetes Mellitus, Hypertension, Cardiovascular Diseases, Fatigue
- Trial name
- NCT02950142
- Testing
- CPOE with order sets for lab testing, CPOE without order sets for lab testing
- Where
- Belgium
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cardiovascular Diseases, Heart Diseases
Genetic Architecture of Plasma T-PA and PAI-1
To determine the effects of six genes on thrombotic risk factors known to be associated with the development of heart disease.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Thrombosis, Atherosclerosis
- Trial name
- NCT00007410
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)