Clinical trials: Cost Effectiveness
Out-of-hours Care Services, Primary Healthcare
The Effect of Substitution of Out-of-hours Care From General Practitioners to Nurse Practitioners
The aim of this study is to explore the effects of substitution in out-of-hours primary care. In consecutive stages an extra General Practitioner (GP) is substituted by a Nurse Practitioner (NP) aiming at replacing 3 out of 4 GPs…
- Trial name
- NCT02407847
- Testing
- care provided by Nurse Practitioners
- Where
- Netherlands
- Volunteers
- 9,647 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Sarcoma
Economic Evaluation of Sarcoma Patients Management in France
The aim of this project is to (1) evaluate the efficiency of early management of sarcoma patients by the sarcoma referral network (NETSARC) vs.
- Trial name
- OPTISARC (NCT05272358)
- Testing
- NETSARC network
- Where
- 25 sites in France
- Volunteers
- 2,431 people
- Sponsor
- Centre Leon Berard
Schizophrenia, Schizotypal Disorder
The OPUS YOUNG Trial. Early Intervention Versus Treatment as Usual for Adolescents With First-episode Psychosis
The OPUS YOUNG (OY) study investigates the efficacy of early intervention service versus treatment as usual (TAU) for adolescents aged 12-17 years with a first-episode psychosis.
- Conditions
- Schizophrenia, Schizotypal Disorder, Delusional Disorder, Acute and Transient Psychotic Disorder, Unspecified
- Trial name
- OPUS-YOUNG (NCT04916626)
- Testing
- OPUS YOUNG, Treatment as Usual
- Where
- Denmark
- Volunteers
- 284 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Heart Failure
Telemedicine for Patients Suffering From Heart Failure (Danish Telecare North Trial)
There are two main aims in this study. The first objective is to evaluate whether a particular telehealth solution, in addition to standard treatment and care, lead to a significant decrease in the mortality and an increase in…
- Trial name
- TCN (NCT02860013)
- Testing
- Telemedicine
- Where
- Denmark
- Volunteers
- 600 people
- Sponsor
- Aalborg University
Pneumonia, Primary Health Care
Tools for the Integrated Management of Childhood Illness (TIMCI): Evaluation of Pulse Oximetry & Clinical Decision Support Algorithms in Primary Care
By introducing pulse oximetry, with or without clinical decision support algorithms, to primary care facilities in India, Kenya, Senegal and Tanzania, the Tools for Integrated Management of Childhood Illness (TIMCI) project aims…
- Conditions
- Pneumonia, Primary Health Care, Child Health, Hypoxia
- Trial name
- TIMCI (NCT04910750)
- Testing
- Pulse oximetry, Clinical Decision Support Algorithm
- Where
- 27 sites in Tanzania
- Volunteers
- 167,517 people
- Sponsor
- Swiss Tropical & Public Health Institute
White Spot Lesion of Tooth
Clinical Outcomes, Cost-Effectiveness and Patient Satisfaction of Two Resin Infiltration Systems for The Management of White Spot Lesions
The aim of this study is to clinically evaluate and compare the color matching of white spot lesions (WSLs) following treatment with two resin infiltration systems: ICON resin infiltration and I-Mate resin infiltration.
- Trial name
- NCT07799350
- Testing
- light cured low viscosity resin infiltration
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Asthma in Children
Cost Effectiveness Analysis of a Randomized Control Trial of q3h vs. q4h Albuterol as Discharge Criteria From the Hospital for Pediatric Asthma Exacerbations
Asthma is the most common chronic condition among children, and the third leading reason for hospitalization of children in the United States.
- Trial name
- NCT04542005
- Testing
- q3h albuterol
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Smoking Cessation, Pregnancy Related
Effectiveness and Cost-effectiveness of a Tailored Text Message Programme (MiQuit) for Smoking Cessation in Pregnancy
The trial aims to determine whether or not MiQuit (text-message support programme) is effective when offered in addition to standard behavioural support for smoking cessation in pregnancy.
- Trial name
- NCT03231553
- Testing
- MiQuit text message support programme
- Where
- 17 sites in United Kingdom
- Volunteers
- 1,000 people
- Sponsor
- University of Nottingham
Gastric Cancer
the Optimal Surveillance Frequency for Stage II/III Gastric Cancer
Due to lacking of evidence on surveillance for gastric cancer (GC), this study aimed to determine the optimal postsurgical surveillance strategy for stage II/III GC patients and compare its cost-effectiveness with traditional…
- Trial name
- NCT05465993
- Where
- China
- Volunteers
- 2,311 people
- Sponsor
- Fujian Medical University
Human Immunodeficiency Virus
Package of Resources for Assisted Contact Tracing: Implementation, Costs, and Effectiveness
Having health workers assist HIV-infected persons with the recruitment and testing of their sexual contacts and biological children is an effective and efficient way of identifying additional HIV-infected persons in need of HIV…
- Trial name
- PRACTICE (NCT05343390)
- Testing
- Enhanced implementation package, Standard implementation package
- Where
- 33 sites in Malawi
- Volunteers
- 841 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
HIV, Hypertension
SEARCH SAPPHIRE Phase A: A Multisectoral Strategy to Address Persistent Drivers of the HIV Epidemic in East Africa
The randomized trials in this record will assess effectiveness, fidelity and cost of prevention and treatment interventions for HIV and hypertension with the objective of informing a population-based study of multi-sectored…
- Conditions
- HIV, Hypertension, Alcohol Drinking, Maternal Child Health
- Trial name
- SAPPHIRE PhA (NCT04810650)
- Testing
- Mobility Dynamic Treatment Intervention, Health Living Intervention for Heavy Alcohol Users, Hypertension Linkage
- Where
- 2 sites in Kenya, Uganda
- Volunteers
- 2,233 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Burns
Impact of a Clinical Decision Algorithm on Length of Hospital Stay and Costs of Care of Burned Patients
Reliable and valid assessment of burn wound depth or healing potential is essential to treatment decision-making, to provide a prognosis, and to compare studies evaluating different treatment modalities.
- Trial name
- NCT03876340
- Testing
- Treatment algorithm, Current treatment
- Where
- Mexico
- Volunteers
- 44 people
- Sponsor
- Hospital Central "Dr. Ignacio Morones Prieto"
Severe Combined Immunodeficiency, Atypical
Generalized Neonatal Screening of Severe Combined Immunodeficiencies
Severe combined Immunodeficiencies ( SCID ) are a group of inherited diseases of the immune system by characterised profound abnormalities of T cell development .
- Trial name
- DEPISTREC (NCT02244450)
- Testing
- SCID screening
- Where
- 51 sites in France
- Volunteers
- 190,539 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Burns
Cost-effectiveness of Laser Doppler Imaging in Burn Care
Accurate early burn depth assessment is important to determine the optimal treatment. The most applied method to asses burn depth is clinical assessment. This method is the least expensive, but not very accurate.
- Trial name
- NCT01489540
- Testing
- laser Doppler imager (Moor)
- Where
- 3 sites in Netherlands
- Volunteers
- 200 people
- Sponsor
- Association of Dutch Burn Centres
Newborn; Infection
The Effect of Implementation of Bundle for Preventing Blood Culture Contamination in Neonatal Intensive Care Unit
In this study, investigators aimed to evaluate the impact of blood culture bundles on the incidence of contamination in the neonatal intensive care unit (NICU).
- Trial name
- NCT06637696
- Testing
- Blood Culture Bundle
- Where
- Turkey (Türkiye)
- Volunteers
- 320 people
- Sponsor
- Dr. Behcet Uz Children's Hospital
Asthma
CAMP Air: Efficacy and Cost-effectiveness in Urban Adolescents
This study will test the efficacy and cost-effectiveness of Controlling Asthma Program for Adolescents (CAMP Air), an e-health intervention, among urban predominately Black and Hispanic adolescents with uncontrolled asthma.
- Trial name
- NCT05091034
- Testing
- Controlling Asthma Program for Adolescents (CAMP Air), Attention Control Asthma Education Intervention
- Where
- United States
- Volunteers
- 374 people
- Sponsor
- Columbia University
Child Malnutrition
Effectiveness and Cost-Effectiveness of Four Formulations of Food Supplements for the Prevention of Wasting and Stunting in Burkina Faso
This research will serve as a follow-up on the review of Title II commodities performed by the Food Aid Quality Review at Tufts University in October 2011.
- Trial name
- FAQR-Burkina (NCT02071563)
- Testing
- CSB14, RUSF1, SC+
- Where
- Burkina Faso
- Volunteers
- 6,039 people, healthy volunteers welcome
- Sponsor
- Tufts University
Hearing Loss
The Hearing Aid Effectiveness After Aural Rehabilitation (HEAR) Trial
This study compares the effectiveness of hearing aid appointments provided in a group format to those provided in an individual format.
- Trial name
- NCT00260663
- Testing
- Group hearing aid fittings, Group hearing aid follow-up
- Where
- United States
- Volunteers
- 660 people
- Sponsor
- US Department of Veterans Affairs
Clinical Trial
AFRI Childhood Obesity Prevention Challenge Area
This study is a hybrid type 2 effectiveness-implementation trial of the Family Check-Up 4 Health (FCU4Health), an adapted version of the Family Check-Up, in pediatric primary care.
- Trial name
- NCT04469816
- Testing
- Family Check-Up 4 Health, Services as Usual
- Where
- 4 sites in United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Typhoid, Paratyphoid Fever
Introduction of the Vi Polysaccharide Typhoid Vaccine in Hue City, Central Vietnam
This study is part of International Vaccine Institutes (IVI)'s typhoid Vi demonstration project that aims to accelerate the rational introduction of Vi vaccines in typhoid endemic countries.
- Trial name
- NCT00131820
- Testing
- Typhoid Vi vaccine, Hepatitis A (control)
- Where
- Vietnam
- Volunteers
- 100,742 people, healthy volunteers welcome
- Sponsor
- International Vaccine Institute