Clinical trials: DM
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
AI-Predicted Disease Trajectories in Diabetes: A Retrospective Study
The study explores the utilization of artificial intelligence (AI) to predict disease progression trajectories in patients with diabetes.
- Trial name
- AI-TRYDIA (NCT06280729)
- Testing
- AI-Analyis
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- IRCCS San Raffaele
Rett Syndrome
Placebo Controlled Trial of Dextromethorphan in Rett Syndrome
Dr. Sakkubai Naidu, Principal Investigator, is initiating a double blinded placebo controlled clinical drug trial using dextromethorphan (DM) in Rett Syndrome (RTT), at the Pediatric Clinical Research Unit (PCRU) of the Johns…
- Trial name
- PCTDMRTT (NCT01520363)
- Testing
- dextromethorphan
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Diabetes Mellitus
The Effect of NVFS on GC in Individuals With DM: SR & MA of RCTs
Purpose of Study (The Effect of Non-Viscous Fibre Supplementation on Glycemic Control (NVFS \& GC) in Individuals with Diabetes Mellitus.
- Trial name
- NVFS&GC (NCT03259724)
- Where
- Canada
- Volunteers
- 514 people
- Sponsor
- Unity Health Toronto
Colorectal Cancer
Association of Colorectal Cancer With Nutrition, Diet, Obesity, Diabetes Mellitus, and Genetic Alterations in Taiwan
We will explore the genetic (including APC, k-ras, p53, MSI, etc.) and environmental (including family history, life style, diet, nutritional status, DM, serum IGF-I, IGFBP-3, etc.) risk factors of colorectal tumorigenesis.
- Trial name
- NCT00172757
- Where
- Taiwan
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Vitamin D Deficiency, Diabetes
Vitamin D and Inflammatory Markers of Cardiovascular Disease in African Americans With Type 2 Diabetes
Recent clinical trials in non diabetics showed that vitamin D supplementation markedly reduced serum levels of C-reactive protein (CRP), interleukin-6, and tissue matrix metallo-proteinases.
- Trial name
- NCT01153243
- Testing
- Ergocalciferol
- Volunteers
- 117 people
- Sponsor
- Cook County Health
Diabetes Mellitus, Type 1, Child
The Effect of Mobile Application on the Pediatric Diabetes Management
Type 1 DM; It is a chronic metabolic disease that develops as a result of the destruction of pancreatic ß cells, which are responsible for insulin production.
- Conditions
- Diabetes Mellitus, Type 1, Child, Adolescent
- Trial name
- DM (NCT05333185)
- Testing
- DİABOT (mobile application robot )
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Dokuz Eylul University
Gestational Diabetes, Diabetes, Gestational
Gestational Diabetes: a Cohort Study
Gestational diabetes (GDM) is the most common hormonal complication during pregnancy. Its occurrence implies an increased risk of maternal and fetal complications and, therefore, its diagnosis and treatment are extremely…
- Conditions
- Gestational Diabetes, Diabetes, Gestational, Diabetes Mellitus in Pregnancy, Diabetes Mellitus, Type 2
- Trial name
- NCT03307486
- Where
- Brazil
- Volunteers
- 1,400 people
- Sponsor
- University of Sao Paulo General Hospital
Diabetes Mellitus, Insulin-Dependent
Psychosocial Issues in Insulin Pump Therapy in Children With Type 1 Diabetes Mellitus (DM)
The effect of change in diabetes treatment from multiple daily insulin injection therapy to continuous subcutaneous insulin infusion on psychosocial outcome measures (quality of life, diabetes burden, parents stress level, fear…
- Trial name
- pumpkin (NCT01338922)
- Testing
- Continuous subcutaneous insulin infusion therapy, Multiple daily injection therapy
- Where
- 24 sites in Germany
- Volunteers
- 211 people
- Sponsor
- University Hospital Schleswig-Holstein
Breast Cancer Detection, Dense Breast Parenchyma
Delphinus SoftVue™ ROC Reader Study (DMT SV RRS3)
The purpose of this multi-reader, multi-case (MRMC) reader study is to evaluate reader performance when SoftVue™ automated breast ultrasound and screening mammography are combined, compared to screening mammography alone, in…
- Conditions
- Breast Cancer Detection, Dense Breast Parenchyma, Benign Breast Findings, Normal Breast Screening
- Trial name
- DMT SV RRS3 (NCT04260620)
- Testing
- Reading of Automated Breast Ultrasound in conjunction with Screening Mammography
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Delphinus Medical Technologies, Inc.
Long-term and Permanent Contraceptive Methods
A Prospective Observational Study of the Clinical Performance of Zarin in Madagascar
This one-year observational study will monitor the contraceptive effectiveness, safety and acceptability of Zarin during the first year of use after the method has been approved for public use in Madagascar.
- Trial name
- NCT01200576
- Where
- Madagascar
- Volunteers
- 621 people, healthy volunteers welcome
- Sponsor
- FHI 360
Diabetes Mellitus, Type 1, Diabetes
The T1D Exchange Registry
The T1D Exchange Registry is a research study, conducted over time, for individuals with type 1 diabetes and their supporters. Participants volunteer to provide their data for research (for example, by answering questions in…
- Conditions
- Diabetes Mellitus, Type 1, Diabetes, Type 1 Diabetes, Diabetes Mellitus
- Trial name
- T1D Registry (NCT04629586)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 50,000 people
- Sponsor
- T1D Exchange, United States
Breast Cancer, Breast Neoplasms
Delphinus SoftVue™ ROC Reader Study
The purpose of this multi-reader, multi-case (MRMC) reader study is to evaluate reader performance when SoftVue™ automated breast ultrasound and screening mammography are combined, compared to screening mammography alone, in…
- Trial name
- DMT SV RRS1 (NCT03698942)
- Testing
- Reading of Automated Breast Ultrasound in conjunction with Screening Mammography
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Delphinus Medical Technologies, Inc.
Diabetes, Diabetes (DM)
Time in rANge vs. Time in nOrmal Glycemia for Better Glycemic Control
The TANGO study is a 12-month study involving 120 children and adolescents with Type 1 Diabetes (T1D) across the Czech Republic, Israel, and Poland who use automated insulin delivery (AID) systems.
- Conditions
- Diabetes, Diabetes (DM), Diabetes Type 1
- Trial name
- TANGO (NCT07376850)
- Testing
- Structured Diabetes Education, Automated Insulin Delivery (AID) System Adjustment
- Where
- 3 sites in Czechia, Israel and 1 more
- Volunteers
- 120 people
- Sponsor
- University Hospital, Motol
Diabetes (Insulin-requiring, Type 1 or Type 2), Pediatric Diabetes
A Novel Miniature Equine-Assisted Diabetes Education Program for Youth: Evaluating the Diabetes Equine Empowerment Program (DEEP).
The Diabetes \& Equine Empowerment Program (DEEP) is a research study evaluating a novel diabetes education program that combines hands-on interactions with miniature horses and evidence-based diabetes self-management education…
- Conditions
- Diabetes (Insulin-requiring, Type 1 or Type 2), Pediatric Diabetes, Diabetes (DM)
- Trial name
- DEEP (NCT07822555)
- Testing
- Diabetes & Equine Empowerment Program (DEEP)
- Volunteers
- 50 people
- Sponsor
- Nemours Children's Clinic
Myotonic Dystrophy Type 1, Congenital DM1
Remote Assessments and Genetic Determinants of Congenital and Childhood Myotonic Dystrophy
Myotonic dystrophy type 1 (DM1) can affect people in many different ways, even in the same family. The symptoms that children experience can be different and more severe than adults.
- Conditions
- Myotonic Dystrophy Type 1, Congenital DM1, Juvenile DM1, Childhood DM1
- Trial name
- REACH-DM KIDS (NCT07630389)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Rochester
Diabetes Mellitus
Cohort of Mexican Children With Diabetes Mellitus (CMC-DM)
The aim of this study is the identification of complications in diabetes mellitus pediatric patients and to compare the clinical, anthropometric, and biochemical characteristics between children in the different types of diabetes…
- Trial name
- CMC-DM (NCT02722655)
- Where
- Mexico
- Volunteers
- 500 people
- Sponsor
- Hospital Regional de Alta Especialidad del Bajio
Diabetes (DM), Physical Activity
Effect of Regular Physical Activity in Normal-Weight Individuals With Type 2 Diabetes and Abdominal Obesity
Individuals with T2DM accompanied by abdominal obesity tend to experience worse clinical outcomes. To identify modifiable factors that may improve these outcomes, the investigators conducted a retrospective cohort study using…
- Trial name
- PA-NormalWtDM (NCT07071545)
- Testing
- Regular physical activity, No regular physical activity
- Volunteers
- 249,247 people
- Sponsor
- Samsung Medical Center
Type II Diabetes Mellitus
The Use of a Computer Program to Help Primary Care Providers Treat Patients With Type 2 Diabetes
The primary purpose of this study is to determine whether the use of CADS by primary care providers (PCPs) for their patients with type 2 diabetes (T2DM) changes the quality of care relative to a "usual care" group in terms of…
- Trial name
- CADS (NCT01648244)
- Testing
- Computer-Assisted Decision Support
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Walter Reed National Military Medical Center
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Non-communicable Diseases (NCDs)
Community-Based Chronic Disease Care in Rural Lesotho
This ComBaCaL cohort study is to assess the impact of community-based, lay-led chronic disease screening and care interventions in rural Lesotho.
- Trial name
- ComBaCaL (NCT05596773)
- Where
- 2 sites in Lesotho, Switzerland
- Volunteers
- 17,500 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland