Clinical trials: Debility
Velopharyngeal Insufficiency, Articulation Disorders
Efficacy of an Arabic Articulatory Error Remediation Software Program in Patients With Velopharyngeal Valve Dysfunction:
To develop a remediation software program that is specific for correcting speech errors in patients with velopharyngeal dysfunction in the Arabic language and test its efficacy, on one group comparing pre and post results
- Conditions
- Velopharyngeal Insufficiency, Articulation Disorders, Hypernasality Syndrome Due to Velopharyngeal Weakness
- Trial name
- NCT04392817
- Testing
- Arabic Articulatory Error Remediation software program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alaa Mamdouh
Postural Imbalance, Muscle Weakness
Effects of Corrective Exercises in Adolescent Fencers
The goal is to learn if a Functional Corrective Training (FCT) exercise program improves posture, core muscle endurance, jumping ability, and reaction time in adolescent fencers.
- Conditions
- Postural Imbalance, Muscle Weakness, Athletic Performance
- Trial name
- FMS exercise (NCT06927778)
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Cerebral Palsy, Hemiplegia
The Effect of Combined Armeospring and CIT on Neuro-motor and Functional Recovery in Children With Unilateral CP
The purpose of this study is to assess the use of a commercially available arm weight supporting training system (Armeo®Spring) in conjunction with Constraint Induced Therapy (CIT) for improving upper extremity function for…
- Conditions
- Cerebral Palsy, Hemiplegia, Upper Extremity Weakness
- Trial name
- NCT02914925
- Testing
- ArmeoSpring/CIT
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- St Mary's Hospital for Children
Urinary Incontinence, Pelvic Floor Muscle Weakness
Dose-response of Physical Exercise on Pelvic Floor Muscle Function in Postmenopausal Women With Urinary Incontinence
Urinary incontinence (UI) symptoms are highly prevalent among women, and menopause is one of the risk factors for UI. During the menopausal transition, not only the hormonal secretion is changed but also the level of physical…
- Trial name
- NCT04351750
- Testing
- general exercise, pelvic floor muscle training
- Where
- Taiwan
- Volunteers
- 47 people
- Sponsor
- National Cheng Kung University
Pain, Traumatic Brain Injury
The NRC Dataset. Developing a Minimum Dataset for Multidisciplinary Rehabilitation: a Modified E-Delphi Study
Several rehabilitation datasets are presently in use for specific patient groups in England. The 'National Clinical Audit of Specialist Rehabilitation for patients with complex needs following major injury' (NCASRI) evaluated…
- Conditions
- Pain, Traumatic Brain Injury, Major Trauma, Multiple Sclerosis
- Trial name
- NCT06726135
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- ThomasCorbett
Hemiparesis, Stroke
Functional Electrical Stimulation for Children With Upper Limb Weakness Post Stroke
A new technology system called MyndMove has been developed by MyndTec Inc. (Missisauga Canada) to administer FES. The purpose of this technology is to improve voluntary upper limb (hand and arm) function (i.e.
- Trial name
- NCT03147794
- Testing
- MyndMove
- Volunteers
- 3 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Children, Cerebral Palsy
Reliability and Validity of Strength Measurements of the Lower Limbs in Children With Bilateral Spastic Cerebral Palsy.
Specific musculo-tendinous adaptations in children with cerebral palsy (CP) have an influence on muscle strength and consequently on functional behavior and participation.
- Conditions
- Children, Cerebral Palsy, Muscle Weakness
- Trial name
- NCT03818152
- Testing
- Functional strength assessment
- Where
- Belgium
- Volunteers
- 24 people
- Sponsor
- University Ghent
Muscle Weakness
Maximal Strength Training in Patients Undergoing Total Hip Arthroplasty
Conventional rehabilitation after total hip arthroplasty (THA) does not seem to restore muscular strength or walking speed. Three-5 years after surgery patients are still not fully rehabilitated.
- Trial name
- NCT02498093
- Testing
- Maximal strength training, conventional rehabilitation
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Norwegian University of Science and Technology
Post-operative Quadriceps Weakness, Post-operative Quadriceps Inhibition
Effect of a Home-based Electrical Stimulation on Quadriceps Function After Knee Surgery
The purpose of this study is to determine if a home-based electrical stimulation (ES) program is more effective than the standard of care (SOC) at improving quadriceps function, functional outcomes, patient reported outcomes, and…
- Conditions
- Post-operative Quadriceps Weakness, Post-operative Quadriceps Inhibition, Adherence to Post-operative Treatment, Post-operative Lower Extremity Function
- Trial name
- NCT02058862
- Where
- 2 sites in United States
- Volunteers
- 87 people
- Sponsor
- University of Kentucky
ACL - Anterior Cruciate Ligament Deficiency, Muscle Weakness
Isokinetic Muscular Assessment After ACL Ligamentoplasty: Study of Factors Predictive of Muscle Imbalance.
Despite advances in surgery and rehabilitation, the return to sport after anterior cruciate ligament (ACL) reconstruction surgery remains a major challenge. challenge.
- Trial name
- PREDICT-ACL (NCT04071912)
- Where
- France
- Volunteers
- 113 people
- Sponsor
- University Hospital, Caen
Hemiparesis, Hemiplegic Cerebral Palsy
The Impact of Robot Assisted Therapy and Metacognitive Skills Training for Children With Hemiparesis
The Occupational Therapy Department at Boston Children's Hospital is teaming up with MGH Institute of Health Professions to explore the benefits of using robot assisted therapy (Amadeo) and a problem solving approach (Active…
- Conditions
- Hemiparesis, Hemiplegic Cerebral Palsy, Hemiparesis;Poststroke/CVA
- Trial name
- NCT04309266
- Testing
- Amadeo by Tyromotion, Active Learning Protocol for Stroke
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Boston Children's Hospital
Spastic Cerebral Palsy, Physical Therapy Modalities
Effectiveness of Whole-Body Vibration
Cerebral Palsy is the most common cause of severe physical disability in childhood and may present difficulties and limitations that will have an impact on their independence and integration in all social areas.
- Conditions
- Spastic Cerebral Palsy, Physical Therapy Modalities, Vibration; Exposure, Lower Extremity Weakness, Spastic
- Trial name
- WBVibration (NCT06330311)
- Testing
- Physiotherapy
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Complutense de Madrid
Respiratory Muscle Weakness
Inspiratory Training in Children After Fontan
This study will assess physical and respiratory capacity, diaphragmatic mobility and quality of life. Healthy children and children who have undergone Fontan surgery will participate.
- Trial name
- NCT06580808
- Testing
- Fontan Training Group
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Livedoid Vasculitis
Livedoid Vasculopathy: Strong Association With Smoking, Weak Association With Thrombophilia
A screening of patient histories at the clinics of Dermatology of the universities of Zurich, Basel and Bern is performed in order to identify patients with a history of Livedoid vasculopathy.
- Trial name
- NCT05878327
- Testing
- Thrombophilia screening
- Where
- 3 sites in Switzerland
- Volunteers
- 15 people
- Sponsor
- University of Zurich
Muscle Weakness, Critical Illness
Critical Illness Neuromuscular Abnormalities in Neurocritical Care Patients
The aim of this research is to investigate critical illness neuromuscular abnormalities in neurocritical care patients.
- Trial name
- NCT00893633
- Where
- Russia
- Volunteers
- 135 people
- Sponsor
- Clinical Institute of the Brain, Russia
ACL Injury, Knee Injuries
Association Between 4-Month Isokinetic Testing Measures and Second Knee Injuries After Primary Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) is a frequent and disabling injury in athletes. Most of the time, ACL reconstruction (ACLR) is consider for regaining function and returning to preinjury sports while reducing the risk of…
- Conditions
- ACL Injury, Knee Injuries, Muscle Weakness
- Trial name
- PREDICT-ACLv2 (NCT05897970)
- Testing
- Return-to-sport (RTS) follow-up
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Caen
Duchenne Muscular Dystrophy, Lower Urinary Tract Symptoms
Examination of Lower Urinary System Symptoms With Duchenne Muscular Dystrophy
The aim of this study is to examine the prevalence of lower urinary tract symptoms (LUTS) in children with Duchenne Muscular Dystrophy (DMD) and the relationship between functional level, posture, muscle strength, pelvic floor…
- Conditions
- Duchenne Muscular Dystrophy, Lower Urinary Tract Symptoms, Muscle Weakness, Posture Disorders in Children
- Trial name
- NCT05464446
- Testing
- Baseline Bubble Inclinometer, Baseline Digital İnclinometer and Hoggan microFET2 devices
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Lokman Hekim University
Thymidine Kinase 2 (TK2)
A RETROspective Study of Patients With TK2d
This is a medical chart review study to collect information for patients who have been taking pyrimidine nucleosides for treatment of TK2 deficiency.
- Trial name
- RETRO (NCT03701568)
- Testing
- dC/dT
- Where
- 8 sites in United States, Israel and 1 more
- Volunteers
- 38 people
- Sponsor
- Zogenix MDS, Inc.
Gait Impairment, Cerebral Palsy (CP)
Clinical Investigation to Validate the Safety and Performance of the ABLE Kids Device in Pediatric Patients With Neurological Gait Disorders in a Clinical Setting
The primary objective of the study is to validate the safety and clinical performance of the ABLE Kids device in pediatric patients with neurological gait disorders or muscular weakness during a 10-session gait training program…
- Conditions
- Gait Impairment, Cerebral Palsy (CP), Neuromuscular Diseases (NMD), Spinal Cord Injuries (SCI)
- Trial name
- NCT07745712
- Testing
- ABLE Kids
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- ABLE Human Motion S.L.
Pediatric Burns, Burn Injury
Plyometrics for Strength and Function After Pediatric Burns
Pediatric burn survivors may experience persistent deficits in lower-limb strength, explosive power, and functional performance after hospital discharge.
- Conditions
- Pediatric Burns, Burn Injury, Post-Burn Rehabilitation, Rehabilitation
- Trial name
- NCT07590557
- Testing
- Plyometric Training, Standard Exercise Program
- Where
- Saudi Arabia
- Volunteers
- 62 people
- Sponsor
- Qassim University