Clinical trials: Deliberate Self-Harm
Depressive Symptoms
Efficacity of Psychological Intervention on Reducing the Suicidal Ideations, Depression Level and Improving Reinsertion
Suicide is the third leading cause of death in adolescents and young adults in the United States and the second leading cause in European countries.
- Trial name
- MLADO (NCT03655730)
- Testing
- weekly psychotherapeutic individual sessions, Usual care
- Where
- France
- Volunteers
- 159 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Suicide and Self-harm
Preventing Suicide With Safe Alternatives for Teens and Youths (SAFETY)
Suicide is the leading cause of death in the age span 10-19 years in Sweden. The most robust predictor of future suicide attempt and suicide death is prior suicide attempt.
- Trial name
- SAFETYF2022 (NCT05537623)
- Testing
- Safe Alternatives for Teens and Youths (SAFETY), Supportive Therapy
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Region Stockholm
Self-harm, Suicide
Artificial Intelligence Self Harm Application
This is a mixed-methods study. The quantitative component will comprise of a multicentre rater-blind, randomized controlled trial to evaluate the feasibility and acceptability of AISHA in addition to treatment as usual (TAU)…
- Trial name
- AISHA (NCT06019663)
- Testing
- The Artificial Intelligence intervention for Self-Harm prevention Application (AISHA) is a mobile intervention based on Y-CMAP
- Where
- 2 sites in Pakistan
- Volunteers
- 312 people
- Sponsor
- Pakistan Institute of Living and Learning
Firearm Injury, Pediatric Emergency Medicine
Randomized Trial to Improve Safe Firearm Storage
The goal of this clinical trial is to test the effect of providing gun locks to caregivers of children presenting to the emergency department for mental health concerns.
- Conditions
- Firearm Injury, Pediatric Emergency Medicine, Suicide and Self-harm, Mental Health Issue
- Trial name
- FARTHER (NCT05568901)
- Testing
- Lethal means counseling, Provision of Cable-style gun locks
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Suicide, Suicide, Attempted
SAFETY-Parent: Online Learning Module to Support Parents of Suicidal Youth
This project aims to adapt the parent component of Safe Alternatives for Teens and Youth (SAFETY) outpatient intervention to SAFETY-Parent (SAFETY-P), a self-paced interactive learning module for parents, to be implemented as an…
- Conditions
- Suicide, Suicide, Attempted, Suicide and Self-harm, Suicide Threat
- Trial name
- SAFETY-P (NCT06460220)
- Testing
- Safe Alternatives for Teens and Youth - Parent (SAFETY-P), Treatment As Usual (TAU)
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- Jennifer Hughes
Suicidal Ideation, Deliberate Self-harm
An Online Intervention to Reduce Self-Harm Among Persons With High Emotion-Related Impulsivity
The goal of this program is to test a brief, online, cognitive behavioral intervention for people who struggle with self-harm or suicidal urges or behavior in the context of emotion-related impulsivity.
- Conditions
- Suicidal Ideation, Deliberate Self-harm, Impulsivity
- Trial name
- NCT04781166
- Testing
- Calm program
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of California, Berkeley
Self-Injurious Behavior
Imaginator: a Pilot of Brief Functional Imagery Training for Self-harm
Self-harm has substantial personal impacts as well as costs on the National Health Service (NHS). Around 13-17% of young people report experiences of self-harm.
- Trial name
- Imaginator (NCT02914847)
- Testing
- Functional Imagery Training (FIT)
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical Research Council
Borderline Personality Disorder, Suicide and Self-harm
Trial of a Brief Psychological Intervention for Suicidal Patients with Borderline Personality Disorder in the Emergency Department
When in crisis, people with borderline personality disorder (BPD) frequently seek care in emergency departments (EDs) often presenting with suicide and self-harm behaviour.
- Trial name
- NCT04779099
- Testing
- Brief 4-session intervention for borderline personality disorder, Treatment as usual
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Centre for Addiction and Mental Health
Self-harm, Suicidal Ideation
CaMaPi for Adolescents/Young People With a History of Self-harm and Suicidal Ideation in Jos, Nigeria
Suicide and self-harm are global disease burden that contributes significantly to years of lost life and mortality.
- Trial name
- CaMaPi (NCT06440031)
- Testing
- CaMaPi, TAU
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Nottingham Trent University
Suicide, Suicide Prevention
Focused Suicide Prevention Strategy for Youth Presenting to the Emergency Department With Suicide Related Behaviour
Suicide is the leading cause of death due to illness among Canadian youth, claiming more lives than any medical illness, including cancer. Suicide prevention is possible, and early intervention is needed.
- Conditions
- Suicide, Suicide Prevention, Suicidal Ideation, Self-Injurious Behavior
- Trial name
- IAMSAFE (NCT06225661)
- Testing
- SAFE Intervention, NAV (Telephone Navigation)
- Where
- 4 sites in Canada
- Volunteers
- 330 people
- Sponsor
- The Hospital for Sick Children
Suicidal Behavior, Self-Harm, Deliberate
Randomized Trial of Stepped Care for Suicide Prevention in Teens and Young Adults
This randomized controlled trial will evaluate two approaches to achieving the aspirational goal of Zero Suicide within a health system: 1) Zero Suicide Best Practices initiated through a zero suicide quality improvement…
- Conditions
- Suicidal Behavior, Self-Harm, Deliberate, Suicidal Ideation, Suicide
- Trial name
- Step2Health (NCT03092271)
- Testing
- Stepped Care for Suicide Prevention, Zero Suicide Quality Improvement
- Where
- 2 sites in United States
- Volunteers
- 301 people
- Sponsor
- University of California, Los Angeles
Self-Harm, Depression
Signatures of N-Ac for Non-Suicidal Self-Injury in Adolescents
To measure NAC-induced changes to concentrations of glutathione (GSH) in the anterior cingulate cortex (ACC) as measured by magnetic resonance spectroscopy (MRS) in 36 adolescents and young adults with NSSI (12 in each group…
- Conditions
- Self-Harm, Depression, Suicide
- Trial name
- NCT04005053
- Testing
- N-acetyl cysteine
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Minnesota
Anorexia Nervosa, Atypical Anorexia Nervosa
Specialist Supportive Clinical Management (SSCM) for Children and Adolescents With Anorexia Nervosa and Atypical Anorexia Nervosa
This study evaluates an adaptation of Specialist Supportive Clinical Management (SSCM) for children and adolescents aged 13-17 years with anorexia nervosa or atypical anorexia nervosa receiving outpatient treatment at the…
- Trial name
- SSCM-Youth (NCT07893145)
- Testing
- Specialist Supportive Clinical Management for Children and Adolescents (SSCM-Youth)
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska Institutet
Self Harm
PsiloIMAGINE: A Psychedelic-augmented Mental Imagery-based Intervention for Young People With Self-harm
Approximately 20% of young people experience self-harm behaviour in their lives. Self-harm can occur across different mental health disorders, and lead to negative outcomes and risk of suicide.
- Trial name
- PsiloIMAGINE (NCT06798636)
- Testing
- Psilocybin 5 mg with cognitive behavioural therapy intervention
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Imperial College London
Inflammatory Bowel Diseases, Depressive Episode
Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health
This study is a large population-based analysis in the United Kingdom (UK) using routine primary care data to investigate the impacts on quality-of-life outcomes and use of healthcare services in people aged 5 - 25 years…
- Conditions
- Inflammatory Bowel Diseases, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorder
- Trial name
- NCT05206734
- Testing
- No specific intervention
- Where
- United Kingdom
- Volunteers
- 19,469 people, healthy volunteers welcome
- Sponsor
- Momentum Data
Self Injurious Behavior, Adolescent Behavior Problem
IMAGINATOR 2.0: Co-design and Early Evaluation of a Novel Blended Digital Intervention Targeting Self-harm in Young People
This study aims to investigate acceptability and feasibility of a new version of the Imaginator intervention, Imaginator 2.0, targeting self-harm behaviour in young people aged 12-25 under mental health services in the UK.
- Conditions
- Self Injurious Behavior, Adolescent Behavior Problem, Child Behavior Problem, Mental Health Disorder
- Trial name
- IMAG2 (NCT06311084)
- Testing
- Imaginator 2.0
- Where
- United Kingdom
- Volunteers
- 29 people
- Sponsor
- Imperial College London
Self Harm, Suicidal Idealtion
Self Harm in Females of South Asian Family Origin
Aim of the study is to adapt and develop a culturally appropriate psychological intervention and to pilot test it's feasibility, and acceptability for the adult South Asian females presenting to general hospital emergency…
- Conditions
- Self Harm, Suicidal Idealtion, Hopelessness
- Trial name
- NCT00884078
- Testing
- Culturally adapted manualized problem solving training
- Where
- 3 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- Lancashire Care NHS Foundation Trust