Clinical trials: Delivery Delayed
Cerebral Palsy, Cerebral Palsy (CP)
Assessing Intellectual and Motor Outcomes in High-risk Infants
Cerebral palsy (CP) is a condition when a baby has a brain injury that affects their movement and muscle tone. Some people with CP can have other developmental issues, like learning impairments, but many do not and have isolated…
- Conditions
- Cerebral Palsy, Cerebral Palsy (CP), Cerebral Palsy Children, High-risk Infants
- Trial name
- AIM-High (NCT06857539)
- Where
- 4 sites in Ireland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University College Cork
Neurodevelopmental Abnormality
Two Year Developmental Follow-up for PREMOD2 Trial (Premature Infants Receiving Milking or Delayed Cord Clamping)
An extension of the PREMOD2 trial, the PREMOD2 Follow-Up trial will evaluate the neurodevelopmental outcomes at 22-26 months corrected age of preterm children who received UCM or DCC.
- Trial name
- PREMOD2FU (NCT03476980)
- Testing
- Randomized to Umbilical Cord Milking at birth, Randomized to Delayed Cord Clamping at birth
- Where
- 18 sites in United States, Canada and 2 more
- Volunteers
- 1,200 people
- Sponsor
- Sharp HealthCare
Intraventricular Hemorrhage, Sepsis
Protective Effects of Delayed Cord Clamping in Very Low Birth Weight (VLBW) Infants
The purpose of this study is to determine whether the intervention of delaying cord clamping for 30 to 45 seconds followed by one milking of the cord while simultaneously lowering the VLBW infants below the introitus will result…
- Trial name
- NCT00818220
- Testing
- delayed umbilical cord clamping, Immediate cord clamping
- Where
- United States
- Volunteers
- 211 people
- Sponsor
- University of Rhode Island
Preterm Birth, Language Development
Very Preterm Children With Language Delay and Parent Intervention
In studies of children born at term, language delay at the age of 2 years exhibits a spontaneously favourable course in 30 to 50% by the age of 3 years.
- Conditions
- Preterm Birth, Language Development, Speech Therapy
- Trial name
- EPILANG (NCT02042235)
- Testing
- Parent-implemented intervention
- Where
- 15 sites in France
- Volunteers
- 67 people
- Sponsor
- Lille Catholic University
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Autism Spectrum Disorder, Autism Spectrum Disorder (ASD)
Intranasal Insulin for Autism Spectrum Disorder in Children and Young Adults Aged 4 to 21 Years
This observational study evaluates the real-world use of intranasal insulin in children and young adults with autism spectrum disorder (ASD) utilizing the ViaNase™ device developed by Kurve Therapeutics.
- Conditions
- Autism Spectrum Disorder, Autism Spectrum Disorder (ASD), Autism Spectrum Disorder High-Functioning, Autism Spectrum Disorder With Absence of Functional Language
- Trial name
- IN-INS-AUT (NCT07521371)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Healing Hope International
Crigler-Najjar Syndrome
Gene Transfer Clinical Study in Crigler-Najjar Syndrome
This is a Phase 1/2, multinational, open-label, ascending-dose, delayed-treatment concurrent control clinical study to evaluate the safety and preliminary efficacy of AT342 in subjects with Crigler-Najjar aged ≥1 year.
- Trial name
- VALENS (NCT03223194)
- Testing
- AT342
- Where
- 4 sites in United States, Israel and 1 more
- Volunteers
- 1 people
- Sponsor
- Audentes Therapeutics
Preterm Birth, Sensory Processing Disorder
Sensory Processing Associated With Motor Skills
In the study, sensory processing skills of 1-year-old preterm and term children will be evaluated. The relationship between sensory processing skills and gross and fine motor development will be investigated.
- Conditions
- Preterm Birth, Sensory Processing Disorder, Motor Delay
- Trial name
- NCT06216379
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Gazi University
Very Low Birth Weight Infant, Placental Transfusion
Extrauterine Placental Transfusion In Neonatal Resuscitation Of Very Low Birth Weight Infants
To investigate the effect of extrauterine placental transfusion (EPT) compared to delayed cord clamping (DCC) on the mean hematokrit on the first day of life in very low birth weight infants (VLBW) born by caesarian section.
- Conditions
- Very Low Birth Weight Infant, Placental Transfusion, Anemia
- Trial name
- EXPLAIN (NCT03916159)
- Testing
- Extrauterine placental transfusion (Intervention group), Delayed cord clamping (Control group)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Universitätsklinikum Köln
Amblyopia, Child
Early Vision Screening in High-risk Children
To evaluate the effect of early vision screening with automated photorefraction device in high risk children
- Trial name
- NCT02678468
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Delay Cord Clamping, Placental Trasfusion
Position at Birth,Placental Transfusion Volume and Cord Clamping
To compare the evolution of the infant's weight before delayed cord clamping (2 minutes after birth) as an indirect measure of the volume of placental transfusion in a group of healthy and fullterm newborns, placed at the level…
- Trial name
- NCT01497340
- Testing
- Position at introitus level, Position at Maternal Abdomen
- Where
- Argentina
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Salud Materno Infantil
Infant Development, Infant,Premature
Movement-based Infant Intervention
The objective is to pilot test the effectiveness of an evidence-based intervention to promote positive neurodevelopmental outcomes in infants at risk for developmental delay.
- Conditions
- Infant Development, Infant,Premature, Infant, Very Low Birth Weight, Infant, Small for Gestational Age
- Trial name
- NCT03082313
- Testing
- Movement Intervention
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Southern California
Premature Infant, Umbilical Cord
Umbilical Cord Milking vs Delayed Cord Clamping in Preterm Infants Born by Cesarean Section
The purpose of this study is to determine whether the umbilical cord milking in preterm infants born by cesarian section less than 34 weeks is more effective than delayed cord clamping to obtain higher levels of hemoglobin.
- Conditions
- Premature Infant, Umbilical Cord, Milking, Delayed Clamping
- Trial name
- NCT02187510
- Testing
- Umbilical cord milking, Delayed cord clamping
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Corporacion Parc Tauli
Preterm Birth, Development Delay
Evaluation of Digital Follow up of Preterm Infants
The aim is to study how a digital follow up tool can identify the preterm born children and their families who need further support or clinical interventions
- Conditions
- Preterm Birth, Development Delay, Sensory Disorder, Growth Disorders
- Trial name
- ePIPARI (NCT05238168)
- Testing
- ePIPARI digital follow up tool
- Where
- Finland
- Volunteers
- 70 people
- Sponsor
- Turku University Hospital
Preterm Birth
Brief Delay in Cord Clamping and Neurobehaviour in Preterms
RESEARCH HYPOTHESIS Brief delay(>30 sec to <60 sec ) in cord clamping as compared to early cord clamping (< 20 sec) leads to a better short term neurobehavioural outcome in preterm (34-36 wks) neonates when assessed by…
- Trial name
- NCT01753843
- Testing
- early cord clamping, Brief Delay in cord clamping
- Where
- India
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Lady Hardinge Medical College
Premature Infant, Developmental Delay
A Parent Administered Sensorimotor Intervention and Developmental Outcome of Preterm Infants
Advances in medical technologies over the last three decades have increased survival rates in infants born preterm . Preterm infants are at high risk of developing developmental delays.
- Trial name
- NCT03836326
- Testing
- Sensorimotor intervention, Control, Story telling attention refocusing intervention
- Where
- Canada
- Volunteers
- 94 people
- Sponsor
- Dr. Sandra Fucile
Placental Transfusion
Delayed Cord Clamping and Use of Oxytocin
The purpose of this study is to determine if oxytocin administration immediately after delivery of the infant modifies the volume of placental transfusion in healthy term infants.
- Trial name
- NCT02618499
- Testing
- Timing of administration of post partum Oxytocin
- Where
- Argentina
- Volunteers
- 180 people
- Sponsor
- Fundacion para la Salud Materno Infantil
Preterm
Efficacy of a Video-based, Parent-centered Home Developmental Intervention for Infants at High Risk for Developmental Delay: a Multicenter Randomized Controlled Trial
The purpose of this study is to determine whether the Motor Composite Score on the Bayley-III (administered at 6 months of corrected age) shows significant improvement in an intervention group-receiving usual care combined with a…
- Trial name
- NCT07882199
- Testing
- Family-centered developmental training intervention
- Volunteers
- 170 people
- Sponsor
- Seoul National University Hospital
HIV-1 Infection, Receipt of Cal-1 Modified Hematopoietic Cellular Products
Long Term Follow up for the Detection of Delayed Adverse Events in Cal-1 Recipients
Long term safety follow-up of Cal-1 recipients
- Trial name
- NCT02390297
- Testing
- Blood tests
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- Calimmune, Inc.
Intraventricular Hemorrhage, Sepsis
Placental Transfusion Project for Preterm Infants
The American College of Obstetrics and Gynecology, American Academy of Pediatrics and the World Health Organization have recently published recommendations related to placental transfusions in preterm infants.
- Conditions
- Intraventricular Hemorrhage, Sepsis, Necrotizing Enterocolitis
- Trial name
- NCT02400697
- Testing
- <30 wks gestation or 1500 grams
- Where
- United States
- Volunteers
- 2,856 people
- Sponsor
- Indiana University