Clinical trials: Development Disorder, Child
Osteogenesis Imperfecta (OI)
Open-label Extension of Study 20130173 of Denosumab in Children and Young Adults With Osteogenesis Imperfecta
To evaluate long-term safety of denosumab in children/young adults with pediatric osteogenesis imperfecta (OI) who completed the prior study 20130173 (NCT02352753).
- Trial name
- NCT03638128
- Testing
- Denosumab, Alternative osteoporosis medications
- Where
- 22 sites in United States, Australia and 10 more
- Volunteers
- 75 people
- Sponsor
- Amgen
Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
OT Intervention Via Telehealth for Children With ASD and ADHD
This study aims to measure the impact of a telehealth-based model of occupational therapy (OT) treatment on clinical outcomes for children with autism spectrum disorder (ASD) and/or attention deficit hyperactivity disorder…
- Trial name
- NCT03957993
- Testing
- Occupational Therapy via Telehealth, Standard of Care Occupational Therapy
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism Spectrum Disorder
Parent Skills Training for Families of Children With Autism Spectrum Disorder
The study is focused on helping parents master the basic intervention skills and evaluate the effectiveness of this parental training style for children with autism spectrum disorder in China.
- Trial name
- NCT03864289
- Testing
- Parent skills training
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Children's Hospital of Fudan University
Autism Spectrum Disorder, Autistic Disorder
Risk Factors and Prognosis of Autism Spectrum Disorder
This case-control study with prospective follow-up aims to identify risk factors associated with autism spectrum disorder and to evaluate the prognosis of children with ASD attending Assiut University Children's Hospital.
- Conditions
- Autism Spectrum Disorder, Autistic Disorder, Child Development Disorders, Pervasive
- Trial name
- NCT07818460
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Assiut University
Achondroplasia
An Extension Study to Evaluate the Efficacy and Safety of BMN 111 in Children With Achondroplasia
The intent and design of this Phase 3 study is to assess BMN 111 as a therapeutic option for the treatment of children with Achondroplasia
- Trial name
- NCT03424018
- Testing
- BMN 111
- Where
- 24 sites in United States, Australia and 5 more
- Volunteers
- 119 people
- Sponsor
- BioMarin Pharmaceutical
Autistic Disorder, Catatonia
Improving the Understanding of Catatonia in Autism
Catatonia is a neuropsychiatric syndrome which is frequently missed or misdiagnosed among psychiatric patients. The current project is a systematic examination of catatonia which will characterize the phenotype and identify…
- Trial name
- A-CAT (NCT02945423)
- Sponsor
- University of Michigan
Self-Injurious Behavior, Autism Spectrum Disorder
Deep Brain Stimulation for Severe Self-Injurious Behaviour in Children
Deep Brain Stimulation for the Treatment of Severe Refractory Self-Injurious Behaviour in Children with Autism Spectrum Disorder: A Randomized Trial To evaluate the effectiveness of deep brain stimulation (DBS) of the nucleus…
- Trial name
- NCT06529380
- Testing
- DBS ON, DBS OFF
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- The Hospital for Sick Children
Stress Disorders, Traumatic, Psychological Trauma
Effect Study of SMART Treatment for Youth
The goal of this clinical trial is to learn if Sensory motor arousal regulation treatment (SMART) works better than treatment as usual (TAU) to treat youth 7-17 years with complex trauma histories and self-regulation…
- Conditions
- Stress Disorders, Traumatic, Psychological Trauma, Sexual Trauma, Stress Disorders, Post-Traumatic; Mental Disorders
- Trial name
- UTVID (NCT07200713)
- Testing
- Treatment as usual (TAU), Sensory motor arousal regulation treatment (SMART)
- Where
- 4 sites in Norway
- Volunteers
- 120 people
- Sponsor
- Vestre Viken Hospital Trust
Autism, Sociocommunicative Challenges
Improving Autism Program Quality in Special Education Units: The Use of an APERS-based Model to Support Student Learning and Participation
This study assesses the effect of using the Autism Program Environment Rating Scale (APERS) as a tool for providing feedback, in-service training, and coaching to school staff in order to improve program quality in special…
- Trial name
- NCT07830160
- Testing
- APERS+
- Where
- Sweden
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Stockholm University
Transition-age Youth, Developmental Disabilities
Evaluation of Project TEAM (Teens Making Environmental and Activity Modifications)
The purpose of this study is to determine the extent to which Project TEAM (Teens making Environment and Activity Modifications) is an effective, socially valid, and feasible intervention that prepares youth with developmental…
- Conditions
- Transition-age Youth, Developmental Disabilities, Cerebral Palsy, Autism
- Trial name
- ProjectTEAM (NCT02714868)
- Testing
- Project TEAM, Matched Comparison
- Volunteers
- 82 people
- Sponsor
- Boston University Charles River Campus
Autism Spectrum Disorder, Eosinophilic Gastrointestinal Disorders
Umbilical Cord Blood Therapy in a Child With Eosinophilic Duodenitis and Autism Spectrum Disorder: a Case Study
This single-case exploratory clinical study aims to evaluate the therapeutic potential of umbilical cord blood (UCB) infusion in a pediatric patient diagnosed with both eosinophilic duodenitis (ED) and autism spectrum disorder…
- Trial name
- NCT06995274
- Testing
- Umbilical Cord Blood Infusion (Autologous and Allogeneic)
- Volunteers
- 1 people
- Sponsor
- Bundang CHA Hospital
Molar Incisor Hypomineralization
Prevalence of Molar Incisor Hypomineralization Among a Group of Egyptian Children in Fayoum Governorate Schools
Determining the Prevalence of Molar Incisor Hypomineralization Among a Group of Egyptian Children in Fayoum Governorate Schools via clinical examination.
- Trial name
- NCT04420520
- Volunteers
- 135 people
- Sponsor
- Cairo University
Fibrous Dysplasia
Study of Denosumab for Prevention of Skeletal Disease Progression in Children With Fibrous Dysplasia
Background: Fibrous dysplasia (FD) is a disease that affects the bones. It causes bone lesions that can become weak and lead to fractures, deformity, and nerve injuries.
- Trial name
- NCT05419050
- Testing
- denosumab
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Autism
Folate Rechallenge
New evidence suggests that autistic disorder (AD) may be associated with abnormalities in folate metabolism, which is a process that affects genetic expression by facilitating the formation of methyl donors for DNA methylation.
- Trial name
- NCT00672360
- Testing
- Folic acid
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Baylor College of Medicine
Autism Spectrum Disorder
Feasibility and Safety of a Virtual-Reality Based Job Interview Training Tool in Teenagers With High-Functioning Autism
The current project involves the application of a VR job training software. We propose to use an interactive VR job interview practice system, Virtual Reality Job Interview Training (VR-JIT), in youths with ASD at the highschool…
- Trial name
- NCT04773548
- Testing
- VR-JIT
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Autism
Evaluating Pathways Mutual Gaze Protocol on Social Skills in Young Children Suspected of Autism
Purpose of the Study: The goal of this clinical trial is to find out if a technique called the "mutual gaze procedure," used in Pathways Early Intervention (Pathways), is the key to helping improve social communication, language…
- Trial name
- NCT06596226
- Testing
- Pathways Parent Mediated Intervention, Pathways Parent Mediated Intervention without Mutual Gaze
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The University of Texas at Dallas
Small for Gestational Age Infant, Growth Hormone Treatment
A Real World Study of the Effect of Early PEG-rhGH Therapy on Cognitive Development of SGA Infants
Cognitive impairment is independently related to low birth weight, low birth length and small head circumference. SGA children who have not experienced height and / or head circumference catch-up have the worst cognitive…
- Conditions
- Small for Gestational Age Infant, Growth Hormone Treatment, Cognitive Developmental Disorder
- Trial name
- NCT05144035
- Testing
- PEG-rhGH
- Where
- China
- Volunteers
- 138 people
- Sponsor
- Tongji Hospital
Asthma in Children
The Role of Biomarkers in the Occurrence and Development of Asthma
To study the expression level of biomarkers such as GITRL in peripheral blood of children with asthma and analyze their correlation with the severity of asthma.
- Trial name
- NCT05768399
- Testing
- The level of biomarkers in Peripheral blood
- Where
- China
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Chongqing Medical University
Nutrition Disorder, Child, Nutrition Disorders in Adolescence
Health and Nutrition Survey on Shenzhen Children
1. Master and analyze the nutritional health, growth and development status of primary and secondary school students in Shenzhen, and discover the main nutritional health, growth and development problems and influencing factors.
- Conditions
- Nutrition Disorder, Child, Nutrition Disorders in Adolescence, Nutritional Deficiency, Nutrition, Healthy
- Trial name
- NCT05244785
- Where
- China
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Shenzhen Center for Chronic Disease Control
Arrest of Bone Development or Growth, Constitutional Delay of Growth and Puberty
YoUng Adolescents' behaViour, musculoskeletAl heAlth, Growth & Nutrition
More children will survive to adulthood today than at any other point in human history, as evidenced by the proportion of live births and absolute numbers.
- Conditions
- Arrest of Bone Development or Growth, Constitutional Delay of Growth and Puberty, Malnutrition, Child, Gestational Diabetes
- Trial name
- YUVAAN (NCT05603793)
- Testing
- Knowledge, Attitude & Practices
- Where
- India
- Volunteers
- 1,304 people, healthy volunteers welcome
- Sponsor
- Hirabai Cowasji Jehangir Medical Research Institute