Clinical trials: Developmental Disorder
Motor Skills Disorders
Taekwondo for Children With Developmental Coordination Disorder
Objectives: To evaluate the effects of a novel adapted Taekwondo (TKD) training programme on skeletal development and motor proficiency in pre-pubertal children with developmental coordination disorder (DCD).
- Trial name
- NCT02635711
- Testing
- Adapted Taekwondo training, Control
- Where
- Hong Kong
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Autism Spectrum Disorder, Autism
Treatment Monitoring in Autism Spectrum Disorder (ASD) in Children
The goal of this clinical study is to learn about the utility and performance of the EarliPoint(™) System: Evaluation for Autism Spectrum Disorder to monitor changes in a child's verbal ability, non-verbal learning, and social…
- Conditions
- Autism Spectrum Disorder, Autism, Developmental Delay, Autism, Early Infantile
- Trial name
- MEASURE-ASD1 (NCT05675371)
- Testing
- Assessment by Expert Clinician During Behavioral Intervention (ABA or similar), Assessment by the EarliPoint Assessment For Autism Spectrum Disorder
- Where
- 9 sites in United States
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- EarliTec Diagnostics, Inc
Autism Spectrum Disorders
Parents Workgroup About Emotion Regulation
The purpose of this study is examine emotional regulation and reflective functioning in parents of children with Autism Spectrum Disorders (ASD) before and after an educational training (four sessions of group workshops).
- Trial name
- NCT02400177
- Testing
- emotion regulation training
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Stanford University
Molar Incisor Hypomineralization
Comparative Evaluation of Giomer Varnish vs Fluoride Varnish as Desensitizing Agents in Teeth With MIH
this clinical trial's aim is to compare two desensitizing agents available in the market to prove which one is more efficient in children with molar incisor hypomineralization complaining from hypersensitivity
- Trial name
- NCT05542667
- Testing
- Giomer varnish, Fluoride varnish
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Physical Activity, Social Responsibility
Imitation-based Dog Assisted Intervention, for Children With Developmental Disabilities.
This R21 application will provide a multidisciplinary One Health approach to DAID physical activity intervention for adolescents with developmental disabilities and their family dog.
- Trial name
- NCT03462407
- Testing
- DAID, Dog walking
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Oregon State University
Edema, Chronic Venous Insufficiency
Validation of a New Method of Limb Volumetry
Volumetry is essential for the diagnosis and follow-up of patients with limb edema. The objective of this project is the validation of real-time reconstruction and calculation of limb volume using a 3D laser scanner.
- Conditions
- Edema, Chronic Venous Insufficiency, Lymphedema
- Trial name
- NCT01574911
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Autism Spectrum Disorder
Family Centered Occupational Therapy on Play Skills and Participation of Children With ASD
Play skills and participation of children with Autism Spectrum Disorder (ASD) have been restricted by their core symptoms, resulting in heightened parenting stress and affected family daily life.
- Trial name
- NCT02795611
- Testing
- Family-centered occupational therapy, regular occupational therapy, intervention done outside our hospital
- Where
- Taiwan
- Volunteers
- 23 people
- Sponsor
- National Taiwan University Hospital
Osteogenesis Imperfecta
Setrusumab vs Placebo for Osteogenesis Imperfecta
The primary objectives of the study are to identify a setrusumab dosing strategy in participants with OI and to evaluate the effect of setrusumab vs placebo on reduction in fracture rate.
- Trial name
- Orbit (NCT05125809)
- Testing
- Setrusumab
- Where
- 43 sites in United States, Australia and 9 more
- Volunteers
- 183 people
- Sponsor
- Ultragenyx Pharmaceutical Inc
Growth Hormone Disorder, Growth Hormone Deficiency in Children
Non-interventional Study of Patients Using Norditropin® for Growth Hormone Deficiency or Turner Syndrome
This study is conducted in Japan. The aim of this study is to collect information about the efficacy and safety of Norditropin® (somatropin) in the long-term treatment of short stature with GHD (Growth Hormone Deficiency) where…
- Conditions
- Growth Hormone Disorder, Growth Hormone Deficiency in Children, Genetic Disorder, Turner Syndrome
- Trial name
- NordiPAD (NCT01604161)
- Testing
- somatropin
- Where
- Japan
- Volunteers
- 2,016 people
- Sponsor
- Novo Nordisk A/S
Overnutrition, Undernutrition
Early Life Nutritional Exposures and Long-term Health and Cognitive Outcomes
This study aims to investigate the relationship of the various exposures during infancy and childhood on later health and development of adolescents.
- Trial name
- NCT01979770
- Where
- Thailand
- Volunteers
- 529 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Polyostotic Fibrous Dysplasia
Studies on Abnormal Bone From Patients With Polyostotic Fibrous Dysplasia and McCune Albright Syndrome
This study will investigate how a gene mutation (change in DNA) causes the abnormal bone in fibrous dysplasia-a condition in which areas of normal bone are replaced with a fibrous growth similar to a scar.
- Trial name
- NCT00001973
- Where
- United States
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Microdeletion Syndromes, Trisomy 21
Development of Non-invasive Prenatal Test for Microdeletion and Other Genetic Syndromes Based on Cell Free DNA
The purpose of this study is to collect blood from families with a child who has been diagnosed with a chromosomal disorder including microdeletions in order to further develop a non-invasive prenatal screening test based on…
- Conditions
- Microdeletion Syndromes, Trisomy 21, Trisomy 18, Trisomy 13
- Trial name
- Microdel Triad (NCT02109770)
- Where
- 2 sites in United States
- Volunteers
- 216 people
- Sponsor
- Natera, Inc.
Hypothyroidism, Global Developmental Delay
Register for Patients With Thyroid Hormone Resistance.
Thyroid hormones (TH) play a pivotal role in the development and function of the mammalian brain. Patients with impaired thyroid hormone transport into the brain tissue or in the case of defective local thyroid hormone receptor…
- Conditions
- Hypothyroidism, Global Developmental Delay, Intellectual Disability, Dystonia
- Trial name
- DEEPTYPE (NCT06566066)
- Testing
- no intervention
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Charite University, Berlin, Germany
Cerebral Palsy, Developmental Delay
Clinical Effectiveness of Increased Standing Time in Non-ambulant Children With Cerebral Palsy:a Pilot Study
Children with cerebral palsy commonly use standing frames to position them to help prevent contracture and deformity and to help their function. There is a lack of evidence to support the correct dosage of standing frame use.
- Trial name
- NCT02141802
- Testing
- Doubling standing time, control
- Where
- 4 sites in United Kingdom
- Volunteers
- 25 people
- Sponsor
- Rachel Rapson
Spinal Muscular Atrophy (SMA)
Spinal Muscular Atrophy (SMA) Biomarkers Study in the Immediate Postnatal Period of Development
Spinal muscular atrophy (SMA) is the leading genetic cause of death of infants. Strong preclinical evidence suggests that effective therapy must be delivered as early as possible to prevent progression of the disease.
- Trial name
- NCT01736553
- Where
- 15 sites in United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Genital Herpes
Serologic Assays for the Diagnosis of Herpes Simplex Virus Type 2
The purposes of this study are: To determine the accuracy of commercially available serologic assays in diagnosing patients with herpes simplex virus type 2 (HSV-2); To assess the sensitivity and specificity of the commerical…
- Trial name
- NCT01112956
- Where
- 3 sites in United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Autism, Pervasive Development Disorder
Atomoxetine, Placebo and Parent Management Training in Autism
The study will evaluate the effectiveness of atomoxetine (Strattera) with and without Parent Management Training (PMT) in children with Autism, Asperger's Disorder, or Pervasive Developmental Disorder Not Otherwise Specified…
- Conditions
- Autism, Pervasive Development Disorder, Asperger's Disorder, Attention Deficit Hyperactivity Disorder
- Trial name
- Strattera (NCT00844753)
- Testing
- atomoxetine, Parent Management Training
- Where
- 3 sites in United States
- Volunteers
- 128 people
- Sponsor
- University of Rochester
Obesity, Child Development
CrescNet - Growth Monitoring Network
CrescNet is a network of primary care physicians and pediatricians (n=219) and endocrinological treatment centers (n=33), established in Leipzig in 1998, whose aim is to improve the early detection of growth disorders.
- Conditions
- Obesity, Child Development, Growth Disorders
- Trial name
- CrescNet (NCT03072537)
- Where
- Germany
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Brain Development Abnormality, Sickle Cell Disease
Brain Structure and Neurocognitive Development in Sickle Cell Disease; a Longitudinal Cohort Study (BRICK Study)
Sickle cell disease (SCD) is an autosomal recessive red blood cell blood disorder. One especially vital organ affected in SCD is the brain.
- Trial name
- BRICK (NCT05564845)
- Testing
- MR scan of the brain, Blood work, Neurological examination
- Where
- 2 sites in Netherlands
- Volunteers
- 84 people
- Sponsor
- Dr. Marjon H. Cnossen MD PhD
ASD
Internal Versus External Attentional Focus in Gross- and Fine-Motor Learning Among Children With Autism Requiring Ongoing Everyday Support
This study examined how different attentional focus instructions affect motor learning in children with autism spectrum disorder (ASD).
- Trial name
- NCT07851272
- Testing
- External Focus of Attention Instructions, Internal Focus of Attention Instructions
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- University of Haifa
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