Clinical trials: Developmental Disorder
Developmental Reading Disorder, Dyslexia
Developmental Dyslexia and Functional Maturation of Auditory Cortex
Developmental dyslexia is a frequent learning disability. The aim of this study is to compare auditory evoked cortical responses to syllables and tones in developmental dyslexia and controls (paired with age, gender).
- Trial name
- DYS-AUT (NCT00245804)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Dental Caries, Molar Incisor Hypomineralization
Management of Molar Incisor Hypomineralization With Silver Diamine Fluoride or SMART
The purpose of this study is to evaluate and compare the clinical performance of Silver diamine Fluoride+Potassium Iodide (SDF+KI) and Silver-Modified Atraumatic Restorative Technique (SMART/SDF+KI+GIC) on molars with MIH
- Trial name
- NCT03862014
- Testing
- SDF+KI, SDF+KI+GIC(SMART)
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Non-Alcoholic Fatty Liver Disease, Obesity
Influence of the Diversity and Composition of the Microbiota in the Development of Pediatric Fatty Liver
The objectives of the present study are: 1) to identify the intestinal and salivary microbiota associated with the presence and severity of hepatic steatosis in children (Study I: case-control study), and 2) to develop a…
- Conditions
- Non-Alcoholic Fatty Liver Disease, Obesity, Metabolic Syndrome
- Trial name
- MicroKid (NCT04575506)
- Testing
- Multidisciplinary intervention program
- Where
- 2 sites in Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Pública de Navarra
Preterm Infant, Motor Activity
Neurobehavioural Development of Infants Born <30 Weeks Gestational Age Between Birth and Five Years of Age
Research question: The primary aim of this study is to compare the prevalence of motor impairment from birth to five years of age between children born <30 weeks and term-born controls, and to determine whether persistent…
- Conditions
- Preterm Infant, Motor Activity, Neurodevelopmental Disorders, Developmental Coordination Disorder
- Trial name
- VIBeS-2 (NCT03172104)
- Where
- Australia
- Volunteers
- 251 people
- Sponsor
- Murdoch Childrens Research Institute
Dyslexia, Developmental, Developmental Language Disorder
Intervention Effectiveness Study of BEtter AT LEarning (BEATLE)- Digital Neuropsychological Rehabilitation Program
The purpose of this study is to evaluate the effectiveness of BEATLE with clinical samples of patients diagnosed with Developmental Language Disorder (DLD), Dyslexia, and Mixed Specific Developmental Disorder.
- Conditions
- Dyslexia, Developmental, Developmental Language Disorder, Specific Learning Disorder, Borderline Intellectual Functioning
- Trial name
- BEATLE (NCT06713863)
- Testing
- BEtter AT LEarning (BEATLE)- Digital Care Pathway
- Where
- 2 sites in Finland
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Developmental Delay
School-based Support for Pre-school Aged Children With Developmental Disabilities and Delays
This proposal aims to test whether a proposed community-clinical linkage (CCL), an educational-medical linkage model, improves access to school-based services and subsequent child, parent, family and health service outcomes and…
- Trial name
- PreM (NCT06145659)
- Testing
- Preschool and Me
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Posterior Fossa Tumors, Pediatric Tumor of Brain
Predicting Cognitive Dysfunction After Pediatric Posterior Fossa Tumor Surgery
The goal of this observational study is to develop and validate a clinical prediction model to identify risk factors for long-term cognitive dysfunction in children (ages 0-18 years) who have undergone surgical resection of a…
- Trial name
- NCT07350382
- Testing
- Not applicable- observational study
- Where
- China
- Volunteers
- 600 people
- Sponsor
- West China Hospital
Autism Spectrum Disorder
Study of Fluconazole in Children With Autism Spectrum Disorder
Antifungal therapy is widely used for individuals with Autism Spectrum Disorders (ASD). The current investigation will examine the effects of fluconazole on behavioral functioning among children with ASD.
- Trial name
- NCT00936182
- Testing
- Fluconazole
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- The Center for Autism and Related Disorders
Autism, Autism Spectrum Disorder
Work Chat: An Interactive Virtual Workday
Nearly 50,000 youth with autism spectrum disorder (ASD) transition from high school to adult life each year with only 25% of these transition-age youth with ASD (TAY-ASD) getting jobs within 2 years of graduation.
- Trial name
- NCT05565482
- Testing
- Work Chat: An Interactive Virtual Workday
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Michigan
Liver Cancer
Prevention for the Development of Liver Tumorigenesis by the Oral Supplementation of Branched-chain Amino Acids
The long-term outcomes of branched-chain amino acid (BCAA) administration in patients undergoing hepatic resection remain unclear.
- Trial name
- NCT01434524
- Testing
- LIVACT
- Where
- Japan
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Kochi University
Executive Dysfunction, Autism Spectrum Disorder
A Hybrid Effectiveness-implementation Trial of a High School-based Executive Function Treatment for Autistic Youth
This study will test the effectiveness of a school-based cognitive behavioral executive function (EF) intervention, Unstuck \& On Target High School (UOT:HS), for transition-age youth with autism spectrum disorder (ASD).
- Conditions
- Executive Dysfunction, Autism Spectrum Disorder, Adolescent Behavior
- Trial name
- NCT05017779
- Testing
- Unstuck & On Target: High School, Treatment as Usual
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- Children's National Research Institute
Amelogenesis Imperfecta, Dental Caries
Clinical Performance of Composites in Patients With Amelogenesis Imperfecta
In AI patients, adhesion still remains the first option in order to achieve an early, minimally invasive intervention, and the altered enamel still represents an acceptable substrate for bonding in some AI variants.
- Conditions
- Amelogenesis Imperfecta, Dental Caries, Dental Composite
- Trial name
- NCT04897724
- Testing
- dental composite
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Neslihan Tekçe
Autism Spectrum Disorder
Characterization of a Clinical Subpopulation in Children With Autism Spectrum Disorder
This single-center, observational study is being conducted to identify a well-characterized subgroup within the ASD patient population, based on clinical symptoms and biosample analysis.
- Trial name
- NCT04600882
- Where
- United States
- Sponsor
- Stalicla SA
Autism
Effects of Hyperbaric Oxygen Therapy on Children With Autism
PURPOSE The purpose of this investigation is to evaluate the cognitive and behavioral effects of Hyperbaric Oxygenation Therapy in children who present with a diagnosis of autism spectrum disorder. HYPOTHESIS 1.
- Trial name
- NCT00406159
- Testing
- Hyperbaric Oxygen Therapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Thoughtful House
Postoperative Pain
Pain Management for Pectus Excavatum Repair
The objective of this study is to scientifically evaluate two different management strategies for post-operative pain after pectus excavatum repair.
- Trial name
- NCT00413582
- Testing
- Epidural Analgesia, Patient-Controlled IV Analgesia
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Children's Mercy Hospital Kansas City
Pain
Preemptive Genotyping and Pain Management
The purpose of this study is to see if testing for genes related to pain and pain management before surgery affects how patients are treated for pain after surgery.
- Trial name
- NCT01813695
- Testing
- Preemptive genotyping in medical record, Genotyping not included in electronic medical record
- Where
- United States
- Volunteers
- 576 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism Spectrum Disorder
Internet-based Treatment for Adults With Autism Spectrum Disorder.
The group of patients diagnosed with Autism spectrum disorder (ASD) is increasing and so is the need for new and effective treatment methods.
- Trial name
- MILAS (NCT03570372)
- Testing
- Internet-based treatment for adults with autism spectrum, Psychoeducation about autism spectum disorder
- Where
- Sweden
- Volunteers
- 84 people
- Sponsor
- Örebro County Council
Exostoses, Multiple Hereditary
Gene Mutations and Orthopaedic Symptoms Correlation of Multiple Hereditary Exostoses: Multicentre Project
The investigator's goal for this project is to examine the causes of the wide variability of the expression of Hereditary Multiple Exostoses (HME).
- Trial name
- NCT00474331
- Where
- Canada
- Volunteers
- 2,000 people
- Sponsor
- University of British Columbia
Development Delay, Child Development
Psychological Correlates of Developmental Delays in Preschool Children
The goal of this observational study is to investigate perinatal, cognitive, linguistic and social-emotional correlates of developmental delays of preschool children.
- Conditions
- Development Delay, Child Development, Social Functioning, Speech Delay
- Trial name
- NCT07420829
- Testing
- Psychological assessment
- Where
- Poland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Bartosz M. Radtke
Breastfeeding, Breastfeeding Education
Improved Child Nutrition and Development Through Social Transfers
The goal of this clinical trial is to learn if a conditional social transfer works to improve rates of complementary breastfeeding.
- Conditions
- Breastfeeding, Breastfeeding Education, Breastfeeding Duration, Breastfeeding Continuation
- Trial name
- TENDER (NCT07569172)
- Testing
- Social Transfer
- Where
- Côte d’Ivoire
- Volunteers
- 1,040 people
- Sponsor
- Swiss Tropical & Public Health Institute
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