Clinical trials: Developmental Disorder
Autism Spectrum Disorder
Leucovorin for the Treatment of Language Impairment in Children With Autism Spectrum Disorder
The purpose of this study is to determine the effectiveness of folinic acid in the treatment of language problems in children with autism spectrum disorder. Folinic acid, also known as leucovorin, is approved by the U.S.
- Trial name
- NCT02839915
- Testing
- Folinic Acid
- Where
- 4 sites in United States
- Volunteers
- 56 people
- Sponsor
- Southwest Autism Research & Resource Center
Ischemic Stroke, Transient Ischemic Attack
Trial of a Secondary Stroke Prevention Program
The purpose of this study is to determine whether an outpatient program can reduce the risk of recurrent stroke.
- Trial name
- NCT01071408
- Testing
- Stroke prevention care program
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Sepulveda Research Corporation
Autism Spectrum Disorder
Parenting a Child With Autism Spectrum Disorder and Marital Status
The purpose of this study is to investigate whether the presence of a child with Autism Spectrum Disorder places parents at increased risk for divorce.
- Trial name
- NCT01435733
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Sheba Medical Center
Autism Spectrum Disorder
Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Single-dose
The goal of this study is to target the neurobiology of restricted and repetitive behaviors in children with autism spectrum disorder using N-acetylcysteine (NAC), a well-tolerated nutritional supplement that has shown promise…
- Trial name
- NCT04278898
- Testing
- N-Acetylcysteine
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Stanford University
Child Development Disorders, Pervasive
Randomized Trial of Parent Training for Young Children With Autism
The purpose of this 24 week study is to determine whether a new Parent Training program is effective in reducing disruptive behaviors in young children with pervasive developmental disorders.
- Trial name
- RUBI (NCT01233414)
- Testing
- Parent Training, Psychoeducational Program
- Where
- 6 sites in United States
- Volunteers
- 180 people
- Sponsor
- Yale University
Autism
Toe Spread Out Exercise With and Without Walking Surface Training in Children With Autism
Flatfoot is a common postural deformity in children, characterized by the collapse of the medial longitudinal arch, leading to abnormal foot posture, gait disturbances, and postural instability.
- Trial name
- NCT07438665
- Testing
- Toe spread out exercise, Toe spread out exercises with walking surface training
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Autism Spectrum Disorder
Study 3 Learning Verbs and Pronouns
The goal of this research is to explore abilities to learn word meanings from overheard speech in children with ASD (and, as a control, typically developing children).
- Trial name
- NCT05193500
- Testing
- Verbs, Pronouns
- Where
- 2 sites in United States
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- New York University
Autism
Pilot Study of Diet and Behavior in Children With Autism
We hypothesize that in children with autism dietary antigens can change the intestine, making it "leaky" and then affecting the brain changing their behavior.
- Trial name
- NCT01625299
- Testing
- Gluten and dry milk
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- The University of Texas Health Science Center, Houston
Social Communication Disorder, Autism
Feasibility Trial of Parent-delivered Social Communication Program
The Hanen Centre®'s More Than Words® (MTW) program is a globally used, parent coaching intervention delivered by speech-language pathologists (SLPs) to parents of children with social communication challenges, including those who…
- Trial name
- NCT06847347
- Testing
- More Than Words®
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- Western University, Canada
Fibrous Dysplasia, McCune Albright Syndrome
Fibrous Dysplasia, McCune-Albright Syndrome Patient Registry
The FD/MAS Patient Registry is an IRB-approved research study that that invites the patients and families to help answer some of the biggest questions about FD/MAS by completing questionnaires about their lives with FD or MAS.
- Conditions
- Fibrous Dysplasia, McCune Albright Syndrome, Mazabraud Syndrome
- Trial name
- NCT03231644
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Tovah Burstein
Developmental Disability
Developing and Examine the Efficacy of the Family-Centered Multi-Sensory Environment Intervention on Parent's Empowerment and Children's Engagement (MSE-PEACE) in Children With Developmental Disabilities and Their Parents: A Mixed Methods Study
The goal of this clinical trial is to learn whether a family-centered multi-sensory environment (MSE-PEACE) can help children with developmental disabilities and support their parents.
- Trial name
- MSE-PEACE (NCT07118293)
- Testing
- MSE-PEACE
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Cheng Kung University
Disorders of Sex Development, Growth Disorders
Identifying New Genetic Causes to Development Disorders
Disorders of growth, puberty and sex development can have genetic causes. The exome analysis could detect new mutations responsible for these disorders and the frequency of these mutations in these disorders, their association…
- Conditions
- Disorders of Sex Development, Growth Disorders, Puberty Disorders
- Trial name
- FORDEV (NCT03283852)
- Testing
- blood sample
- Where
- France
- Volunteers
- 1,100 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Autistic Disorder
Evaluating the Effectiveness of Aripiprazole and D-Cycloserine to Treat Symptoms Associated With Autism
This study will determine the effectiveness of aripiprazole and D-Cycloserine in treating symptoms associated with autism in children.
- Trial name
- NCT00198107
- Testing
- Aripiprazole, D-cycloserine
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Indiana University
Chromosome 22q11.2 Deletion Syndrome
Genetics and Psychopathology in the 22q11 Deletion Syndrome
The purposes of this study are to: 1. study the nature and longitudinal course of psychiatric symptoms in children with the 22q11.2 deletion syndrome and 2. identify genes that contribute to the occurrence of these symptoms.
- Trial name
- NCT00161109
- Where
- 2 sites in United States, Netherlands
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Premature Infant Disease
A Randomized Controlled Trial to Evaluate the Effect of White Noises and Parental Voices As Protectors Against Noise Damage in a Neonatal Intensive Care Unit
The goal of this Randomized Controlled Trial is to test the efficacy of listening to white noises and parental voices against environmental noise damage in premature babies admitted to the Newborn Intensive Care Unit.
- Trial name
- NCT06150404
- Testing
- White Noises and Maternal and/or Paternal voices
- Where
- Italy
- Volunteers
- 11 people
- Sponsor
- Istituto Giannina Gaslini
Tooth Demineralization, Tooth Sensitivity
Graphene-Reinforced CAD/CAM Restorations for MIH-Affected Molars in Adolescents: A Prospective Clinical Study
This study evaluates the clinical performance, marginal integrity, surface wear, color stability, and postoperative sensitivity of graphene-reinforced CAD/CAM indirect restorations (inlays, onlays, overlays) in molars affected by…
- Conditions
- Tooth Demineralization, Tooth Sensitivity, Enamel Mineralization Disorders, Tooth Sensitivity After Composite Restorations
- Trial name
- NCT07329244
- Testing
- Graphene-reinforced CAD/CAM polymer (G-CAM®)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universitat Internacional de Catalunya
Tuberous Sclerosis Complex, TSC Related Cognitive Disability
Efficacy of RAD001/Everolimus in Autism and NeuroPsychological Deficits in Children With Tuberous Sclerosis Complex
Tuberous sclerosis complex (TSC) is a genetic disease that leads to mental retardation in over 50% of patients, and to learning problems, behavioral problems, autism and epilepsy in up to 90% of patients.
- Conditions
- Tuberous Sclerosis Complex, TSC Related Cognitive Disability, TSC Related Autism, TSC Related Learning Problems
- Trial name
- RAPIT (NCT01730209)
- Testing
- Everolimus
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Erasmus Medical Center
Obesity
Can a Physical Activity Skill Development and Parent-Centered Dietary Intervention Help Combat Child Obesity?
The purpose of this study, and its original contribution to research, is to determine the impact of a physical activity skill development and parent centered family weight management program on the weight, cardiovascular health…
- Trial name
- NCT00107692
- Testing
- Physical activity and diet
- Where
- 2 sites in Australia
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University of Wollongong
Perinatal Mental Health
The Development of PATH, a Program to Support NICU Parent Mental Health Through the Transition From Hospital to Home
The objective of this study is to develop and pilot test a telehealth-based mental health screening and engagement program that supports parents as their infants transition home from the NICU.
- Trial name
- NCT06467916
- Testing
- Behavioral Treatment
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- University of Colorado, Denver
ARDS
Retrospective Postoperative ARDS Study at Vanderbilt University
By examining the intraoperative anesthetic characteristics of patients who developed ARDS postoperatively, we hope to identify variables which have a positive or negative association on the development of ARDS.
- Trial name
- NCT00656071
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Vanderbilt University
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