Clinical trials: Developmental Disorder
Infertility
Development of a Screening Tool for Difficult Embryo Transfers
This study aims to investigate the accuracy of a proposed screening tool in identifying difficult embryo transfers (ETs) without doing a mock ET.
- Trial name
- NCT05701072
- Testing
- Oocyte Pick Up, Embryo Transfer
- Where
- 2 sites in United Arab Emirates
- Volunteers
- 200 people
- Sponsor
- ART Fertility Clinics LLC
Autism Spectrum Disorder
Sibling-Mediated Intervention on Literacy and Reciprocity for Children With Autism
Given the increasing prevalence of autism spectrum disorder (ASD), estimated to be 1 in 68 in the United States alone, ASD has become one of the fastest-growing pediatric concerns.
- Trial name
- NCT05098392
- Testing
- Sibling-mediated intervention
- Where
- 3 sites in United States, China
- Volunteers
- 8 people
- Sponsor
- Arizona State University
Language Development Disorders, Speech and Language Disorder
Efficiency of Speech and Language Intervention on Achievement of Children With Developmental Language Disorder
Children with Developmental Language Disorder (DLD) have many linguistic difficulties in syntax, lexicon, morphology and phonology.
- Conditions
- Language Development Disorders, Speech and Language Disorder, Therapy
- Trial name
- DYSPHADEV (NCT04926311)
- Where
- France
- Volunteers
- 130 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Postoperative Pain
Prediction of Acute Postoperative Pain and Analgesic Consumption
Pain is an expected part of surgical recovery but effective pain management remains challenging. The high variability in postoperative pain experience and analgesic treatment response between patients is part of the challenge.
- Trial name
- MIRPEX-3 (NCT02230865)
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Kasper Grosen
Autism Spectrum Disorder, Anxiety
Specifying and Treating Anxiety in Autism Research
In the Specifying and Treating the Anxiety Phenotype in Autism Spectrum Disorder (STAAR) study, we conducted a16-week randomized comparative treatment trial of the Behavioral Intervention for Anxiety in Children with Autism…
- Trial name
- STAAR (NCT03279471)
- Testing
- Sertraline, CBT/BIACA
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of California, Davis
Premature Retinopathy, Visual Impairment
Evaluation of Visual - Motor Development in Children With Retinopathy of Prematurity
The aim of this study was to investigate the eye structure, visual impairment, visual motor development and motor coordination of children between 2-6 ages that had applied to diod laser photocoagulation and intravitreal anti …
- Conditions
- Premature Retinopathy, Visual Impairment, Motor Delay
- Trial name
- NCT03865134
- Testing
- Snellen Test, Autorefractometer, Titmus Stereo Fly Test
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Feeding and Eating Disorders of Childhood
Integrated Eating Aversion Treatment Manual-Parent Version
The purpose of this study is to further develop the integrated Eating Aversion Treatment (iEAT) manual, which is designed to address chronic food aversion in children with chronic food refusal.
- Trial name
- iEAT (NCT02721901)
- Testing
- iEAT Manual Intervention, Control group
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Emory University
Autism, Food Allergies
Treatment of Autistic Children Using NAET Procedures
1. Purpose of this study is to determine whether NAET procedures are effective in the treatment of children with allergy-related autism spectrum disorders in restoring their verbal and nonverbal communication. 2.
- Trial name
- NCT00277407
- Testing
- NAET with acupressure and/or chiropractic procedures
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Nambudripad's Allergy Research Foundation
Down Syndrome
Proactive Speech and Language Intervention for Infants With Down Syndrome
Children with Down syndrome (DS) face life-long struggles with verbal communication. Babble and speech sound development is delayed, and speech can be difficult to understand.
- Trial name
- BBC-DS (NCT06450509)
- Testing
- Babble Boot Camp
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Arizona State University
Autism or Autistic Traits, Family Relations
Transitioning Together Boston
A randomized controlled trial will be conducted to determine the effects of an adapted family-centered autism transition intervention called Transitioning Together/Juntos en la Transición on meaningful outcomes for families.
- Trial name
- NCT05599711
- Testing
- Transitioning Together (TT) / Juntos en la Transicion (JET), Usual autism transition care
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Boston Medical Center
Craniosynostoses, Hypovolemia
Hemodynamic Monitoring During Craniosynostosis Surgery: Comparing Traditional and Newer Technology Monitors (CRASY-PRAM)
Hemodynamic evaluation during pediatric anesthesia is essential to care management. Intraoperative cardiovascular instability is frequent in major surgeries, and appropriate monitoring is necessary to ensure safe anesthetic…
- Conditions
- Craniosynostoses, Hypovolemia, Hemorrhage, Hemodynamic Instability
- Trial name
- CRASY-PRAM (NCT06263075)
- Testing
- Intraoperative monitoring
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Sinusoidal Obstruction Syndrome, Complications of Bone Marrow Transplant
Using Ultrasound Elastography to Predict Development of SOS
Sinusoidal obstruction syndrome (SOS) is a potentially fatal hepatic veno-occlusive disease-affecting children following bone marrow transplantation (BMT).
- Trial name
- NCT02483481
- Testing
- shear wave ultrasound elastography
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Children's Mercy Hospital Kansas City
Autism Spectrum Disorder
Computer-based Social Skills Training for Autism Spectrum Disorder
The primary objective of this study is to evaluate changes in subject performance on social skills assessments after engaging in a gaze-controlled video game that leverages ABA principles of learning, in comparison to an…
- Trial name
- NCT03672344
- Testing
- Lookware TM, Lookware TM Control Module
- Where
- 11 sites in United States
- Volunteers
- 54 people
- Sponsor
- BioStream Technologies, LLC
ADHD, Autism Spectrum Disorder
AWARE: Management of ADHD in Autism Spectrum Disorder
This study is a pragmatic clinical trial examining the comparative effectiveness of two stimulant medications (methylphenidate and amphetamine) in the treatment of ADHD in children and adolescents with autism.
- Trial name
- NCT05916339
- Testing
- Randomization to either Amphetamine (AMP) class of stimulant medication or Methylphenidate (MPH) class of stimulant medication, Randomization to either Alpha 2 agonist class of medication or alternate class of stimulant.
- Where
- 13 sites in United States, Canada
- Volunteers
- 500 people
- Sponsor
- Daniel Coury
Autism, Autism Spectrum Disorder
Comparing Imitation and Stereotyped Behaviors in Autistic Children: Robots vs. Human Operators
Virtual QT is a social robot designed to interact with humans in social and educational contexts. Equipped with visual and vocal interfaces, the robot can recognize and respond to various human inputs, providing emotional support…
- Trial name
- NCT06144528
- Testing
- QT robot
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Developmental Language Disorder and Language Impairment, Anxiety Disorders and Symptoms
Reducing Anxiety Problems Among Children Indicated to Have Developmental Language Disorder
This study aims to pilot a world-first intervention, a mental health intervention augmented for children indicated with developmental language disorder (DLD).
- Trial name
- RAP-iDLD (NCT05552365)
- Testing
- Adapted Cognitive Behavioural, Treatment as Usual
- Where
- Singapore
- Volunteers
- 9 people
- Sponsor
- Nanyang Technological University
Musculoskeletal Diseases, Genetic Disease
Turkish Version of the Affordance in the Home Environment for Motor Development-Toddler (AHEMD-T)
This study aimed to translate the Affordance in the Home Environment for Motor Development -Toddler (AHEMD-T) into Turkish and examine its psychometric properties.
- Conditions
- Musculoskeletal Diseases, Genetic Disease, Metabolic Disease, Delays Developmental
- Trial name
- NCT04556500
- Testing
- investigating the psychometric properties of Turkish Affordance in the Home Environment for Motor Development-Toddler (AHEMD-T)
- Where
- Turkey (Türkiye)
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Motor Skills Disorders, Sensory Processing Disorder
Ayre's Sensory-Motor Integration Exercises and Sensory Modulation And Motor Skills In Children With ASD
This study will adopt a quasi-experimental design, featuring assessments before and after the intervention for both the experimental and control groups.
- Trial name
- NCT07576907
- Testing
- Ayre's Sensory-Motor Integration Exercises
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Diabetes, Endocrine System Diseases
Evaluating Innovations in Transition From Pediatric to Adult Care - The Transition Navigator Trial
The Transition Navigator Trial (TNT) is a pragmatic randomized controlled trial evaluating the effectiveness of usual care plus a patient navigator service versus usual care plus newsletters and other educational materials, to…
- Conditions
- Diabetes, Endocrine System Diseases, Gastro-Intestinal Disorder, Neuro-Degenerative Disease
- Trial name
- TNT (NCT03342495)
- Testing
- Patient Navigator, Usual Care
- Where
- 3 sites in Canada
- Volunteers
- 337 people
- Sponsor
- University of Calgary
Autism Spectrum Disorder, Fecal Microbiota Transplantation (FMT)
Open Label Phase IIa Trial Evaluating the Effect and Safety of Transplantation of Fecal Microbiota in Children With Autism Spectrum Disorders and Gastrointestinal Symptoms
Autism Spectrum Disorders (ASD), affect approximately 1% of the general population and are characterized by impairments in social communication associated with repetitive/stereotyped behaviors.
- Trial name
- FELICITA (NCT07105267)
- Testing
- FMT Protocol
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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