Clinical trials: Diagnostic Support
Inherited Cardiac Conduction Disorder, Cardiomyopathies
A Psychoeducational Intervention Supporting Patients With an Inherited Cardiac Condition
Inherited heart conditions (IHCs) can cause young sudden deaths due to a genetic trait that leads to a thickened heart muscle or abnormal heart rhythms.
- Trial name
- PISICC (NCT03602040)
- Testing
- PISICC
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- King's College London
Prostate Cancer Diagnosis
PROVIZ - a Machine Learning Software, to Support Targeting of Prostate Biopsies on MR Images in Biopsy-naive Patients
To perform a traditional feasibility clinical investigation, as defined in ISO 14155:2020, to investigate preliminary feasibility, safety, and clinical performance information of a near-final design of the investigational…
- Trial name
- NCT06000046
- Testing
- Automatic image analysis
- Where
- Norway
- Volunteers
- 82 people
- Sponsor
- Norwegian University of Science and Technology
Brain and Central Nervous System Tumors, Neuroblastoma
Radiation Therapy, Chemotherapy, and Peripheral Stem Cell Transplantation in Treating Patients With Primitive Neuroectodermal Tumors
RATIONALE: Radiation therapy uses x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00003846
- Testing
- filgrastim, carboplatin, cyclophosphamide
- Where
- 13 sites in United States
- Volunteers
- 25 people
- Sponsor
- Children's Oncology Group
Bone Fractures
AI-Assisted Fracture Detection in Emergency Radiography
This study evaluates whether artificial intelligence (AI) can support doctors who interpret X-rays for suspected fractures in emergency care.
- Trial name
- FAIR (NCT06754137)
- Testing
- BoneView AI-Assisted Radiograph Interpretation
- Where
- 3 sites in Austria, Germany
- Volunteers
- 1,667 people
- Sponsor
- Salzburger Landeskliniken
Cerebral Palsy
Feasibility of Vision-Language Models for Detecting Physical Assistance as an Observable Criterion Defining GMFCS Levels in Children Aged 2 to 6 Years With Cerebral Palsy
The GMFCS sorts children with cerebral palsy into five levels of gross motor function. What mainly separates one level from the next is two things an observer can see: whether another person has to physically help the child move…
- Trial name
- NCT07824531
- Testing
- Vision-language model assessment of movement video
- Where
- 2 sites in South Korea
- Volunteers
- 26 people
- Sponsor
- Samsung Medical Center
Breathless Patients With Any Established Underlying Medical Diagnosis
Development of King's College Hospital Breathlessness Service
Breathlessness is a common, distressing symptom in advanced malignant and non malignant disease, and impacts significantly on quality of life.
- Trial name
- NCT01165034
- Testing
- Breathlessness Support Service
- Where
- United Kingdom
- Volunteers
- 110 people
- Sponsor
- King's College London
Malaria, Malaria in Pregnancy
ERASE - Impact of COVID-19 on Malaria Control
Objective: Measure incidence of malaria and malaria-related outcomes, evaluating potential impact of the SARS-CoV2 epidemic and of antimalarial resistance in Oyam and Kole district, Uganda with focus on pregnant women.
- Trial name
- ERASE (NCT05348746)
- Testing
- Advanced Analysis of Polymorphism
- Volunteers
- 300 people
- Sponsor
- Doctors with Africa - CUAMM
Optic Neuropathy, Optic Neuropathy, Ischemic
Building Research With Artificial Intelligence in Neuro-Ophthalmology
The research team, recognized as a world leader in Artificial Intelligence for neuro-ophthalmology, has shown that it is possible to diagnose certain neuro-ophthalmologic or neurologic disorders from a single retinal fundus image…
- Conditions
- Optic Neuropathy, Optic Neuropathy, Ischemic, Optic Neuritis, Optic Nerve Diseases
- Trial name
- BRAIN (NCT06390579)
- Testing
- Deep learning algorithm applied on retrospectively collected color fundus photographs
- Where
- France
- Volunteers
- 693 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Keratoconus, Refractive Surgery
AI-Orchestrated Workflow Versus Consultant Ophthalmologist for Refractive Surgery and Keratoconus Diagnosis (AEYE Trial)
Background and Rationale: Laser vision correction procedures, such as LASIK (Laser-Assisted In Situ Keratomileusis), PRK (Photorefractive Keratectomy), and SMILE (Small Incision Lenticule Extraction), are highly effective but…
- Conditions
- Keratoconus, Refractive Surgery, Machine Learning, Artifical Intelligence
- Trial name
- AEYE (NCT07096232)
- Testing
- Multi-Agent AI Diagnostic Workflow (AEYE)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Hazem Yassin Clinics
Prostate Carcinoma
A Point of Prostate Cancer Diagnosis Virtual Reality Assistant Intervention in Supporting Newly Diagnosed Black Men
This clinical trial tests how well a point of prostate cancer diagnosis (PPCD) virtual reality assistant (ViRA) intervention works in supporting Black men with newly diagnosed prostate cancer.
- Trial name
- NCT07126548
- Testing
- Best Practice, Discussion, Survey Administration
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Mayo Clinic
Diabetic Retinopathy
Clinical Decision Support Algorithm to Predict Diabetic Retinopathy
Diabetic retinopathy (DR), a complication of diabetes, is a leading cause of blindness among working-aged adults globally. In its early stages, DR is symptomless, and can only be detected by an annual eye exam.
- Trial name
- NCT03769948
- Testing
- risk factors for diabetic retinopathy
- Volunteers
- 500 people
- Sponsor
- Oklahoma State University Center for Health Sciences
Upper Respiratory Infection, Lower Resp Tract Infection
Holistic Approach Supporting the Uptake of Innovative Diagnostic Technologies for Respiratory Infections
This observational diagnostic validation study aims to evaluate the clinical performance of novel lateral flow and microfluidic-based technologies for the detection of upper and lower respiratory tract infections in children and…
- Trial name
- HOLICARE (NCT07651865)
- Where
- 3 sites in Ethiopia, Senegal and 1 more
- Volunteers
- 1,765 people
- Sponsor
- Karolinska Institutet
Autism Spectrum Disorder, Parenting
Effectiveness of an Online Psychological Support Program for Mothers of Children With Autism
The aim of this study to evaluate the effectiveness of an online psychological support program for mothers of children diagnosed with Autism Spectrum Disorder (ASD).
- Conditions
- Autism Spectrum Disorder, Parenting, Well-Being, Psychological
- Trial name
- NCT07757295
- Testing
- Online Acceptance and Commitment Therapy-Based Parent Support Program
- Where
- Turkey (Türkiye)
- Volunteers
- 181 people
- Sponsor
- Sabri Hergüner
Urinary Stones, Prostate Cancer
Development of an AI-Agent for Urological Disease Diagnosis and Treatment
Urological diseases such as urinary stones, prostate cancer, and bladder cancer are very common and often require highly specialized diagnosis and treatment.
- Conditions
- Urinary Stones, Prostate Cancer, Bladder Cancer
- Trial name
- NCT07721935
- Where
- 3 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Nursing Students, Decision-Making
The Effect of an Artificial Intelligence-Supported Virtual Reality Simulation on Nursing Students' Holistic Care Skills
This study aims to evaluate the effect of artificial intelligence (AI)-supported virtual reality (VR) simulation on nursing students' holistic care skills.
- Conditions
- Nursing Students, Decision-Making, Diagnostic Reasoning
- Trial name
- AI-VRS (NCT07518199)
- Testing
- AI-VRS, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Gazi University
Osteosarcoma, Osteosarcoma in Children
Effects of Maintenance Cabozantinib+BSC Versus BSC in Children and AYA With Osteosarcoma
The participants of this study will be children, adolescents, and young adults with residual osteosarcoma, which cannot be removed completely through surgery.
- Conditions
- Osteosarcoma, Osteosarcoma in Children, Osteosarcoma in Adolescents and Young Adults
- Trial name
- CabOSTar (NCT06341712)
- Testing
- Cabozantinib, Best Supportive Care (BSC)
- Where
- 16 sites in United States, Belgium and 8 more
- Volunteers
- 10 people
- Sponsor
- Ipsen
Autism Spectrum Disorder
Trial of Autism Parent Navigator Program
To address the dual needs of parents for support in navigating Autistic Spectrum Disorder (ASD) services and maintaining positive family functioning, the investigators propose to test Autism Parent Navigators (APN), an innovative…
- Trial name
- APN (NCT04744428)
- Testing
- Autism Parent Navigators, Peer mentoring
- Where
- United States
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- Penn State University
Juvenile Idiopahtic Arthritis
Improving Outcomes for Juvenile Idiopathic Arthritis
Children and parents often experience uncertainty and stress when juvenile idiopathic arthritis (JIA) is first diagnosed, which creates a need for structured support.
- Trial name
- NCT07659223
- Testing
- The intervention was a one year support program JASP-1
- Where
- Sweden
- Volunteers
- 116 people
- Sponsor
- Region Stockholm
Lower Urinary Tract Symptoms
Primary Care Management of Lower Urinary Tract Symptoms in Men
The PriMUS Study aims to develop a clinical decision support tool to help GPs more accurately diagnose and manage LUTS in men. The study will recruit 880 men across three research hubs in Bristol, Newcastle and Wales.
- Trial name
- PriMUS (NCT03520673)
- Testing
- Urodynamics
- Where
- United Kingdom
- Volunteers
- 725 people, healthy volunteers welcome
- Sponsor
- Cardiff University
Type 1 Diabetes
Personalized Comprehensive Diabetes Support for Children With Newly Diagnosed Type 1 Diabetes
The goal of this clinical trial is to learn if access to a diabetes coach improves quality of life (QOL) for families of children with newly diagnosed type 1 diabetes. The main questions it aims to answer are: 1.
- Trial name
- NCT06057662
- Testing
- personalized comprehensive diabetes support
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, Davis