Clinical trials: Disorder of Vein
Venous Thrombosis Deep (Limbs), Post Thrombotic Syndrome
EXERT: Exercise Physiology After Thrombosis
Deep vein thrombosis (DVT) can cause long-term scarring and narrowing of veins. When there is extensive damage to the veins in the legs, groin or abdomen it can affect the way that blood is able to flow back up to the heart.
- Trial name
- NCT05296499
- Testing
- Cardiopulmonary exercise test (CPET), Exercise cardiac MRI, 6 minute walk test
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Prevention of Venous Thromboembolism, Congenital Heart Disease
An Observational Study to Learn More About How Safe Rivaroxaban is And How Well it Works in Children With Congenital Heart Disease Who Had a Heart Surgery Called the Fontan Procedure
This is an observational study in which the data from children with congenital heart disease will be collected and studied. These children will include those who are prescribed rivaroxaban by their doctors after a heart surgery…
- Conditions
- Prevention of Venous Thromboembolism, Congenital Heart Disease, Fontan Procedure, Children
- Trial name
- NCT06193863
- Testing
- Rivaroxaban (Xarelto, BAY59-7939)
- Where
- Japan
- Volunteers
- 61 people
- Sponsor
- Bayer
Pulsatile Tinnitus
The Recurrence Mechanism of Venous Tinnitus After Boney Wall Reconstruction Based on Multimodal Imaging and Multiphysics Coupling
Venous tinnitus (VT) is seriously affecting the quality of life of five million patients in China. Bony wall reconstruction is the main treatment method, but the postoperative recurrence rate exceeds 30%, and the specific…
- Trial name
- NCT05856175
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
Chronic Venous Disease (CVD), Vein Compliance, Venous Clinical Severity Score (VCSS)
Correlation Between Popliteal Vein Compliance and Venous Clinical Severity Score
When the liquid flow increases, the luminal caliber's stretching amplitude decreases, leading to a higher hydraulic pressure according to Poiseuille's law.
- Trial name
- NCT06175481
- Testing
- Popliteal Vein Compliance
- Where
- China
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Hao Liu
Venous Thromboembolic Disease
Risk Factors of Venous Thromboembolism in Women During Hormonal Exposure
Young women have an increased risk of venous thromboembolism (VTE) during hormonale exposure (estrogen-containing pill or pregnancy).
- Trial name
- FIT-H (NCT03206372)
- Testing
- Case group, Control group
- Where
- 8 sites in France
- Volunteers
- 2,640 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Congenital Heart Disease, Unfractionated Heparin
Comparison of the Best Method for Measuring Anti-Xa Activity in Children Receiving Unfractionated Heparin in Cardiac Intensive Care (COMPAXE-HNF)
This study aims to compare the accuracy of two different blood sampling methods from a central venous catheter (CVC) for measuring anti-Xa activity in children receiving unfractionated heparin (UFH) from this CVC.
- Conditions
- Congenital Heart Disease, Unfractionated Heparin, Anti Xa Activity
- Trial name
- COMPAXE-HNF (NCT07365670)
- Testing
- blood sampling for measuring anti-Xa activity, measurement of anti-XA activity
- Volunteers
- 22 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
HIV Infections
Clinical Performance of Reveal G4 Rapid HIV-1 Antibody Test
To determine the efficacy of an improved rapid diagnostic test using venous whole blood and fingerstick whole blood. The clinical performance of Reveal G4 Rapid HIV-1 Antibody Test will be determined by comparing the results with…
- Trial name
- NCT02190578
- Testing
- Reveal G4
- Where
- 4 sites in United States
- Volunteers
- 1,649 people, healthy volunteers welcome
- Sponsor
- MedMira Laboratories Inc.
Other Acute Illnesses Presenting to the Hospital, Heart Failure
Evaluation of Implementation of a National Point-of-Care Ultrasound Training Program
This VA QUERI Partnered Evaluation Initiative will evaluate the impact of an immersive Point-of-care Ultrasound (POCUS) Training Course on provider skill acquisition and retention; the frequency of POCUS use by trained providers…
- Conditions
- Other Acute Illnesses Presenting to the Hospital, Heart Failure, Pneumonia, Deep Venous Thrombosis
- Trial name
- NCT03296280
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Venous Thromboembolism
Bemiparin Versus Enoxaparin in the Prevention of Venous Thromboembolism Among ICU Patients
The purpose of this study is to compare two types of low-molecular-weight heparin, enoxaparin and bemiparin, as regards their efficacy and safety in venous thromboembolism prevention among intensive care unit patients.
- Trial name
- NCT02795065
- Testing
- Enoxaparin, Bemiparin
- Volunteers
- 100 people
- Sponsor
- Mohamed Sayed Mohamed Abbas
Vascular Access Devices, Catheters
Effectiveness of a Needle-free Connector With Anti-reflux Technology in Reducing Complications From Long Peripheral Venous Catheters in Hospitalised Adult Patients: Randomised Clinical Trial
A study to evaluate a needle-free connector (a stopper) featuring anti-reflux technology (to prevent blood from flowing back) for catheters (polyurethane tubes inserted into a vein), with the aim of reducing complications…
- Conditions
- Vascular Access Devices, Catheters, Occlusion, Thrombosis
- Trial name
- FLUSH-ETI (NCT07519304)
- Testing
- Needle-free connector with neutral fluid displacement and without anti-reflux technology, Needle-free connector with neutral fluid displacement and equipped with anti-reflux technology, Long peripheral venous catheter
- Where
- Spain
- Volunteers
- 62 people
- Sponsor
- Hospital Arnau de Vilanova
Venous Malformations, Arteriovenous Malformations
Microwave Ablation for Treatment of Vascular Malformations: Efficacy and Safety
This clinical trial aims to assess the safety and efficacy of microwave ablation in treating vascular malformations, including both venous malformations (VM) and arteriovenous malformations (AVM).
- Conditions
- Venous Malformations, Arteriovenous Malformations, Microwave Ablation, Vascular Malformations
- Trial name
- NCT07404670
- Testing
- Microwave Ablation
- Volunteers
- 150 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Registry
Real World Study of Deep Venous Thrombosis. Analysis of Prospective Cases in University Hospitals of São Paulo
Background: Deep venous thrombosis (DVT) is a common and important vascular disease due to its morbidity and mortality. Its incidence remains high throughout the world and constitutes serious problems for national and…
- Trial name
- DVT (NCT03388775)
- Testing
- deep venous thrombosis
- Where
- Brazil
- Volunteers
- 800 people
- Sponsor
- Fundação Faculdade Regional de Medicina de São José do Rio Preto
Venous Thromboembolism
Pharmacokinetics, Safety and Tolerability of Dabigatran Etexilate Solution in Children 1 to < 2 Years of Age
Study will assess PK/PD parameters and safety and tolerability of the study medication in this age group
- Trial name
- NCT01773174
- Testing
- dabigatran etexilate
- Where
- 8 sites in United States
- Sponsor
- Boehringer Ingelheim
Varicose Veins, Venous Insufficiency
Lower Limb Venous Insufficiency and the Effect of Radiofrequency Treatment Versus Open Surgery
200 patients with insufficient great saphenous veins will be randomized to either radiofrequency ablation or high ligation/stripping (open surgery).
- Trial name
- NCT02397226
- Testing
- Radiofrequency ablation, High ligation/stripping, Radiofrequency ablation catheter
- Where
- 2 sites in Sweden
- Volunteers
- 198 people
- Sponsor
- University Hospital, Linkoeping
Portal Vein, Cavernous Transformation Of
Cavernous Transformation of Portal Vein： Etiology, Diagnosis, Management and Prognosis
To observe the etiology, diagnosis, management and prognosis of cavernous transformation of portal vein.
- Trial name
- NCT02505113
- Testing
- Montelukast
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Sun Yat-sen University
Stroke
A RCT to Establish the Effectiveness of Intermittent Pneumatic Compression to Prevent Post Stroke DVT
Strokes occur when blood flow to part of the brain is interrupted. Patients are often bedbound for several days or weeks although if they survive, most will make some recovery.
- Trial name
- CLOTS-3 (NCT00789542)
- Testing
- Intermittent Pneumatic compression, Routine care
- Where
- United Kingdom
- Volunteers
- 2,876 people
- Sponsor
- University of Edinburgh
Venous Thromboembolism
Safety and Tolerability of Dabigatran Etexilate Solution in Children 1 to < 12 Years of Age
To investigate the safety and tolerability of dabigatran etexilate solution in children and to obtain preliminary pharmacokinetic/pharmacodynamic data
- Trial name
- NCT01083732
- Testing
- dabigatran etexilate
- Where
- 7 sites in Canada, Italy and 4 more
- Volunteers
- 18 people
- Sponsor
- Boehringer Ingelheim
Total Anomalous Pulmonary Venous Connection, Pulmonary Venous Stenosis
Sutureless Closure for Primary Total Anomalous Pulmonary Venous Connection
The purpose of this study is to assess the percentage of pulmonary venous stenosis after TAPVC repair with sutureless closure.
- Conditions
- Total Anomalous Pulmonary Venous Connection, Pulmonary Venous Stenosis, Sutureless Closure
- Trial name
- TAPVC (NCT04938921)
- Where
- Vietnam
- Volunteers
- 30 people
- Sponsor
- Children's Hospital 1
Venous Thrombosis
Study on the Incidence of Early Deep Vein Thrombosis After Peripherally Inserted Central Catheter Insertion
Deep Vein Thrombosis (DVT) is one of the most important complications after Peripherally Inserted Central Catheter (PICC) insertion. This study goals are to understand when and why DVT develops.
- Trial name
- DVT-PICC (NCT02752984)
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Pulmonary Embolism, Venous Thromboembolism
STRATEGY-PE: Real-World Treatment Strategies for Intermediate-High Risk Pulmonary Embolism
This study aims to compare the effectiveness and safety of three treatment strategies (Anticoagulation, Thrombolysis, and Mechanical Thrombectomy) for patients with intermediate-high risk acute pulmonary embolism (PE) in a…
- Trial name
- STRATEGY-PE (NCT07603700)
- Testing
- Anticoagulants, Thrombolytic Agents, Mechanical Thrombectomy Devices
- Where
- China
- Volunteers
- 1,300 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University