Clinical trials: Electrophysiology
Depressive Symptoms
Efficacy and Biological Targets of Response to rTMS Therapy in Youth Depression
Youth depression is a debilitating disorder that exacts enormous social, economic and personal cost. Unfortunately, treatments which are conventionally used to treat adult depression have often modest to no efficacy in youth and…
- Trial name
- NCT02472470
- Testing
- rTMS
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Centre for Addiction and Mental Health
LAMA2-MD (Merosin Deficient Congenital Muscular Dystrophy, MDC1A)
LAMA2-related Muscular Dystrophy Brain Study
Laminin alpha-2 (LAMA2)-related muscular dystrophy (LAMA2-MD, Merosin Deficient CMD) is a form of congenital muscular dystrophy (CMD).
- Trial name
- NCT01952028
- Where
- United States
- Sponsor
- Cure CMD
Cognitive Development
Fatty Acid Levels and Memory in Breastfed Children
Purpose: To explore the relation between breastmilk nutrients and the cognitive abilities of breastfed infants. Phase 1: Near 3 months of age child and mother saliva samples for DNA obtained with breast milk sample.
- Trial name
- NCT01942434
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Myofascial Trigger Points
A Clinical Observation on Neuropsychology and Electrophysiology in Headache Patinets With Myofascial Trigger Points
To study the clinical characteristics of headache patients with pericranial myofascial trigger points(MTrPs),and to explore the possible pathogenesis of MTrPs,investigators hope to find the possible electrical biomarkers for…
- Trial name
- NCT03082547
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Congenital Cataract
Electrophysiology in Congenital Cataract After Lensectomy and Anterior
In this prospective study , a cohort of 91 eyes with congenital cataract and 25 eyes normal eyes from Wenzhou medical university was erolled.91 eyes with congenital cataract was after lensectomy and anterior vitrectomy as test…
- Trial name
- NCT04427748
- Where
- China
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Supraventricular Tachycardia
Using Non-Fluoroscopic Imaging Devices to Decrease Radiation Exposure During Ablation of Supraventricular Tachycardia
The purpose of this study is to determine whether the additional use of non-fluoroscopic imaging modalities can decrease the use of radiation exposure during standard ablation procedures for supraventricular tachycardia (SVT) in…
- Trial name
- NCT00979303
- Testing
- Intracardiac echocardiography and 3D navigational system
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Boston Children's Hospital
Child Development
Follow up of Long Term Neurodevelopmental Impact of the Type of Feeding During the First Year of Life at 10 Years Old
The Chilean infant Nutrition Trial was a prospective, randomized, double-blind, controlled study conducted in Santiago, Chile, between 2016 and The study aimed to evaluate growth and body composition changes between birth and two…
- Trial name
- NCT06917625
- Testing
- Imaging
- Where
- Chile
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Corporación de Apoyo de la Investigación Científica en Nutrición
Parkinson Disease
Minimal Electrophysiology and Imaging Enhanced Deep Brain Stimulation
The goal of this study is to learn if Deep Brain Stimulation (DBS) surgery can be streamlined for patients being treated for Parkinson's disease.
- Trial name
- MIXT-DBS (NCT06572150)
- Testing
- Deep Brain Stimulation - Minimal Electrophysiology, Deep Brain Stimulation - Standard
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Nova Scotia Health Authority
ADHD - Attention Deficit Disorder With Hyperactivity
Brain Stimulation and Attention Control in Children With ADHD
The goal of this clinical trial is to learn if brain stimulation can help children ages 6 to 12 with attention-deficit/hyperactivity disorder (ADHD) improve their attention and self-control.
- Trial name
- NCT07182344
- Testing
- Intermittent Theta Burst Stimulation to Right DLPFC
- Where
- 2 sites in Kazakhstan
- Volunteers
- 40 people
- Sponsor
- Neurolab Plus
Phelan-McDermid Syndrome, Autism Spectrum Disorder (ASD)
A Controlled Trial of Growth Hormone in Phelan-McDermid Syndrome and Idiopathic Autism
This clinical trial will use growth hormone as a novel treatment for Phelan-McDermid syndrome (PMS) and idiopathic autism. A double-blind, placebo-controlled crossover trial design will be used in 30 children with idiopathic…
- Trial name
- NCT05187377
- Testing
- Growth Hormone, Saline
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Refractory Epilepsy, Neuromodulation
Characterising the Network-Specific Effects of Piriform Cortex Stimulation Via SEEG
The prospective study aims to characterize the network-specific modulatory effects of piriform cortex stimulation in patients undergoing stereotactic EEG for drug-resistant epilepsy.
- Trial name
- NCT07305311
- Testing
- SEEG recordings and SPES
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Xuanwu Hospital, Beijing
Cochlear Implant
Subjective and Objective Results With CI Electrode Types
Background The authors' aim was to compare the influence of various electrode designs on selected objective and subjective clinical outcomes for cochlear implant recipients using the same model of receiver-stimulator, Cochlear™…
- Trial name
- NCT03515473
- Testing
- cochlear implant
- Where
- Hungary
- Volunteers
- 139 people
- Sponsor
- Szeged University
Dystonia
Chronic Outcome Monitoring for DBS in Dystonia
Dystonia is a severe movement disorder involving increased muscular activity and can be very variable. To date, the treatment of dystonia is challenging.
- Trial name
- COMMED (NCT07244549)
- Where
- 3 sites in Germany
- Volunteers
- 25 people
- Sponsor
- Charite University, Berlin, Germany
Stress, Psychological, Stress, Physiological
Stress Inoculation Through Virtual Reality in the Pediatric Electrophysiology Laboratory
The goal of this study is to assess the utility of virtual reality technology to aid in the mental health of patients with cardiac disease, specifically looking at decreasing anxiety and perceptions of pain from stressful…
- Conditions
- Stress, Psychological, Stress, Physiological, Anxiety, Pain Perception
- Trial name
- NCT02949401
- Testing
- Use of Virtual Reality App
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stanford University
Healthy, Neuromuscular Disease
Evaluation of Neuromuscular Disease
The peripheral nervous system is the portion of the nervous system outside of the brain and spinal cord. It includes the 12 pairs of cranial nerves, 31 pairs of spinal nerves and their branches, nerves responsible for sensation…
- Conditions
- Healthy, Neuromuscular Disease, Peripheral Nervous System Disease
- Trial name
- NCT00001201
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Sudden Cardiac Death
The Role of Electrophysiology Testing in Survivors of Unexplained Cardiac Arrest
Sudden cardiac death (SCD) remains a major cause of mortality within developed nations despite aggressive efforts to reduce its societal burden.
- Trial name
- EPS ARREST (NCT03079414)
- Testing
- Invasive Electrophysiology Study
- Where
- 21 sites in United States, Canada and 1 more
- Volunteers
- 100 people
- Sponsor
- Western University, Canada
Ultrasound, Muscle Disease
Role of Ultrasound in Diagnosis of Muscle Diseases
The study aims to provide a timely update on the role of combining clinical and neuromuscular ultrasound assessments in diagnosis and follow-up of various muscle diseases in clinical practice over 12 months period, and…
- Trial name
- NCT04233255
- Testing
- Neuromuscular Ultrasound (US), Electrophysiological studies, Seum CPK, CK-MM levels, Lactate dehydrogenase and alanine aminotransferase.
- Where
- Egypt
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Assiut University
OCD, Tic Disorders
Objective Characterizatoion of Repetitive Behaviors
Introduction: Repetitive behaviors (RB) constitute a broad range of symptoms across different psychiatric/neurologic disorders. The most famous are stereotypies (found in autism), compulsions (found in…
- Conditions
- OCD, Tic Disorders, Gilles de la Tourette Syndrome
- Trial name
- NCT06050369
- Testing
- EEG, MRI
- Where
- 3 sites in France
- Volunteers
- 50 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Schizophrenia / Schizoaffective Disorder, Schizophrenia and Disorders With Psychotic Feature
Building a Computational Model of Auditory Hallucinations
Some people hear voices or sounds that other people cannot hear; these are called auditory hallucinations. The study aims to understand what is happening in the brain when this occurs and will use brain scans to learn more.
- Conditions
- Schizophrenia / Schizoaffective Disorder, Schizophrenia and Disorders With Psychotic Feature, Psychosis, SCHIZOPHRENIA 1 (Disorder)
- Trial name
- CLARITY WP1 (NCT07820553)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- King's College London
Venous Vascular Closure, Electrophysiology Study
Mobilization and Outcomes After Venous Closure
The primary objective of this post-market registry is to collect real-world outcomes and evaluate usage practice of MYNX CONTROL™ VENOUS (MCV) Vascular Closure Device (VCD) 6F-12F in sealing femoral venous access sites in…
- Trial name
- MOVE (NCT07246902)
- Testing
- MYNX CONTROLTM VENOUS Vascular Closure Device
- Where
- 9 sites in United States
- Volunteers
- 339 people
- Sponsor
- Cordis US Corp.