Clinical trials: Embryo
Rabies
Rabies Immunization Concomitant With JEV in Children
Background. The World Health Organization recommends pre-exposure vaccination (PreP) to protect children living in canine rabies endemic countries.
- Trial name
- NCT00703521
- Testing
- Rabies vaccine
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Fertility Disorders
Natural Frozen Embryo Transfer (FET) vs Substituted Frozen Embryo Transfer (FET)
In frozen embryo transfer substituted cycles, patients are treated with progesterone and estrogen in an attempt to mimic the natural cycle and a transfer is planned whenever the endometrium is ready.
- Trial name
- NCT06053827
- Testing
- Frozen embryo transfer
- Where
- Canada
- Volunteers
- 1,207 people
- Sponsor
- Clinique Ovo
Infertility
Implantation and Cytokine Expression
Implantation failure of the embryo might be the result from the environment in the uterus. Proteins (cytokines) are screted by the endometrium which can result in a pro or anti inflammatory environment.
- Trial name
- NCT00264992
- Where
- Netherlands
- Volunteers
- 160 people
- Sponsor
- UMC Utrecht
Embryo Development
Impact of Culture Medium on Embryo Quality
The purpose of this study is to compare two culture media.
- Trial name
- NCT01094314
- Testing
- embryo culture medium
- Where
- Belgium
- Volunteers
- 790 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Fertility
Association Between Euploid Embryo Grade and Maternal Age
Background: Advanced maternal age (AMA) is associated with a reduction in live birth rate (LBR) after ART cycles. The main reason for this reduction is the lower number of oocytes aspirated, the number of developing embryos and…
- Trial name
- NCT06454058
- Where
- United States
- Volunteers
- 502 people
- Sponsor
- Inception Fertility Research Institute, LLC
Endometrium, Laser
Intravenous Laser Irradiation Effect on Treatment Resistant Thin Endometrium
We will recruit 30 poor ovarian responders and thin endometrium patients, aged 35-45 year old, and treat with intravascular laser irradiation of blood (ILIB) via an intravenous catheter for irradiation of the blood under a period…
- Trial name
- NCT03081130
- Testing
- Intravenous laser irradiation treatment
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Veterans General Hospital.
Etiology, Cohort Study
A Cohort Study for Occupational Stress Induced Early Embryonic Death
Occupation stress can be the risk factors of early embryonic death
- Conditions
- Etiology, Cohort Study, Early Embryonic Death, Occupational Stress
- Trial name
- NCT02115438
- Volunteers
- 3,405 people
- Sponsor
- Peking University Third Hospital
Infertility (IVF Patients)
Correlation of the Genetic Constitution of the Spent Blastocyst Media
The main objective of this study is to improve niPGT-A (non-invasive Preimplantation Genetic Testing for Aneuploidies) to avoid the need of a biopsy to perform the genetic analysis of the embryo and to help in understanding the…
- Trial name
- CONNECTED (NCT06780605)
- Testing
- niPGT-A, Multifocal TE biopsies and ICM biopsy
- Where
- 2 sites in Cyprus
- Volunteers
- 230 people
- Sponsor
- Igenomix
Fertility Issues
Correlation of Urinary and Serum Hormone Levels in Natural Cycle Frozen Embryo Transfer Cycles
To evaluate whether the measurement of urinary estrone glucuronide and luteinizing hormone (LH) concentrations with an at-home device is correlated with serum hormone levels within a natural cycle frozen embryo transfer protocol.
- Trial name
- MIRA (NCT06410170)
- Testing
- MIRA Device
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ottawa Fertility Centre
Uterine Peristaltic Frequencies Between Pregnant and Non-pregnant Women in Embryo Transfer Cycles
Comparison of Uterine Peristaltic Wave Frequencies Between Pregnant and Non-pregnant Women in Embryo Transfer Cycles
Eligibility criteria Infertile woemn undergo IVF \& embryo transfer cycles at infertility clinic at King Chulalongkorn Memorial Hospital Measurement Uterine peristaltic wave frequencies \& Junctional zone thickness by 3D-TVUS on…
- Trial name
- NCT03587246
- Testing
- 3DTVUS : Uterine peristaltic frequencies
- Where
- Thailand
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Embryo Development
The Clinical Outcome of Ultra-low Oxygen Tension on Post Thawed Human Blastocyst
The clinical outcome of Ultra-low oxygen tension on post thawed human blastocyst
- Trial name
- NCT03817671
- Testing
- 5% O2, 2% O2
- Where
- Egypt
- Volunteers
- 168 people
- Sponsor
- Ganin Fertility Center
Thalassemia,Embryonic Development,Reproductive Sterility and Infertility
A Retrospective Study on the Effect of HBA or HBB Genetic Defects on Early Embryonic Development
Thalassemia is an anemia or pathological state caused by compounding absently or inadequately of one or more globin chains of hemoglobin due to the defects of the globin gene,and the carrying rate is high in southern China.
- Trial name
- NCT03687567
- Testing
- Preimplantation genetic diagnosis
- Where
- China
- Volunteers
- 737 people
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
IVF
Effect of HCG on Endometrial Preparation in Frozen Embryo Transfer
Intramuscular injection of HCG to prepare endometrium for frozen embryo transfer
- Trial name
- NCT06577181
- Testing
- hCG + estradiol, Observation arm
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Infertility
A Comparison of Ongoing Pregnancy Rate Between Cleavage Stage and Early Compacting Embryo Transfer at 66±2 Hours After ICSI Using Single Step Culture Medium
A comparison of ongoing pregnancy rate between cleavage stage and early compacting embryo transfer at 66±2 hours after ICSI using single step culture medium
- Trial name
- NCT02987075
- Testing
- Compacting embryo transferring, Non- compacting embryo transferring
- Where
- Vietnam
- Volunteers
- 430 people
- Sponsor
- Vietnam National University
Endometrial Receptivity
Comparison of Blood Flow in the Arteriae Uterinae in Ovarian Stimulation Cycles
This study will measure the blood flow in the aa. uterinae in women, undergoing firstly ovarian stimulation for In-Vitro Fertilization (IVF) / Intracytoplasmic sperm injection (ICSI), in Hormonal Replacement cycles (HRT) and…
- Trial name
- NCT03887728
- Where
- United Arab Emirates
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Implantation, Embryo
Longitudinal Clinical Observation of a Digital Twin Model for Blastocyst Evaluation in IVF Clinics
This study aims to develop and validate a non-image, multimodal digital twin model of the human blastocyst using fully de-identified clinical, laboratory, molecular, biochemical, and long-term follow-up data obtained during…
- Trial name
- IVFDT (NCT07305480)
- Testing
- Digital Twin Computational Modeling
- Where
- Austria
- Volunteers
- 1 people
- Sponsor
- Ukraine Association of Biobank
Infertility
Correlating Time-Lapse Parameters Detected by the Eeva™ System With Comprehensive Chromosome Screening Results
The purpose of this research study protocol is to collect imaging data on embryos followed to blastocyst stage (Day 5-6) and correlate Eeva System parameters with comprehensive chromosome screening (CCS) results, implantation and…
- Trial name
- CCS (NCT01635049)
- Where
- 2 sites in United States
- Volunteers
- 110 people
- Sponsor
- Progyny, Inc.
Infertility
Selection of Embryos by Time-lapse
In order to improve success rate by assisted reproductive techniques new techniques are being developed for selection of the embryo with best chance of implantation, establishement of pregnancy and subsequent delivery.The present…
- Trial name
- NCT01138631
- Testing
- Embryoscope
- Where
- Denmark
- Volunteers
- 59 people
- Sponsor
- University of Aarhus
Singeleton Conceived Fresh and Frozen Embryo Transfer (ICSI/IVF), Naturally Conceived
NEURODEVELOPMENTAL OUTCOMES OF SINGLETON CONCEIVED FROM FRESH AND FROZEN EMBRYO TRANSFER COMPARED WITH NATURALLY CONCEIVED
This study aimed to: detect difference in neurobehavior, maturity, Apgar score and birth weight of singleton conceived from fresh and frozen embryo transfer and naturally conceived.
- Trial name
- NCT04772872
- Testing
- Assessment by Brazelton neonatal behavior for group A,Band C
- Where
- Egypt
- Volunteers
- 186 people
- Sponsor
- Cairo University
Virus Diseases, Rabies
A Phase 3 Clinical Trial to Evaluate Long-term Immunogenicity and Boostability of Purified Chick-Embryo Cell Rabies Vaccine in Adults Following Primary Series of Pre/Exposure Prophylaxis.
The aim of this study is to evaluate the long-term (up to approx.10 years) persistence and to assess the boostability of immune responses in participants who received a primary series of accelerated or conventional rabies PrEP IM…
- Trial name
- NCT02545517
- Testing
- Rabipur, Blood sampling, Purified Chick-Embryo Cell Rabies Vaccine
- Where
- 7 sites in Austria, Germany and 1 more
- Volunteers
- 459 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline