Clinical trials: Embryo
Stress, Physiological, Infertility
Evaluation of the Impact of Stress on IVF Outcome
The purpose of this study is to determine if physiological measures of stress, measured by the non-invasive OTO device, are significantly correlated with IVF outcome.
- Conditions
- Stress, Physiological, Infertility, Stress, Psychological
- Trial name
- NCT05589571
- Where
- 43 sites in United States
- Volunteers
- 240 people
- Sponsor
- Inception Fertility Research Institute, LLC
Recurrent Implantation Failure, Infertility
Comparing FET Guided by ERA Vs Standard Timing in Patients with Recurrent Implantation Failure
The pregnancy rate of in vitro fertilisation (IVF) remains around 35% per transfer. Women who are not pregnant following several embryo transfers are regarded as having recurrent implantation failure (RIF), with one of the causes…
- Trial name
- NCT06762626
- Testing
- Frozen embryo transfer according to endometrial receptivity analysis result
- Where
- China
- Volunteers
- 734 people
- Sponsor
- The University of Hong Kong
Etiology, Cohort Study
A Cohort Study for Occupational Stress Induced Early Embryonic Death
Occupation stress can be the risk factors of early embryonic death
- Conditions
- Etiology, Cohort Study, Early Embryonic Death, Occupational Stress
- Trial name
- NCT02115438
- Volunteers
- 3,405 people
- Sponsor
- Peking University Third Hospital
Aneuploidy, Chromosome Abnormality
RCT Study to Validate niPGT-A Clinical Benefit.
Chromosomal aneuploidies are linked with spontaneous miscarriages and abnormal offspring in human pregnancies. In addition, some types of aneuploidies are reported to prevent implantation.
- Conditions
- Aneuploidy, Chromosome Abnormality, Infertility
- Trial name
- niPGT-A_RCT (NCT04000152)
- Testing
- niPGT-A, Morphology criteria
- Where
- 8 sites in Argentina, Brazil and 3 more
- Volunteers
- 296 people
- Sponsor
- Igenomix
PCOS
Live Birth After Letrozole-stimulated Cycles Versus Hormone Replacement Treatment Cycles for the First Frozen Embryo Transfer in Women With PCOS
This is a multicenter randomized controlled trial comparing the efficacy and safety of two endometrial preparation protocols for the first frozen embryo transfer cycle in PCOS with whole embryo freezing.
- Trial name
- NCT05227391
- Testing
- Oral Letrozole, Oral estradiol valerate
- Where
- China
- Volunteers
- 1,078 people
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
PCOS
The Effect of Polycystic Ovary Syndrome on the Embryo Morphokinetics ( PCOS )
Polycystic ovarian syndrome (PCOS) is a complex endocrine and metabolic syndrome which accounts for 75% of women with anovulatory infertility. The cause of infertility in PCOS is already unknown.
- Trial name
- NCT05438355
- Where
- China
- Volunteers
- 153 people
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Repeated Implantation Failure
Intrauterine Injection of Human Chorionic Gonadotrophin and Pregnancy Rate in ICSI
Despite recent advances in clinical and laboratory techniques of Assisted Reproductive Technology (ART), the pregnancy rate remains around 30% per cycle.
- Trial name
- NCT03445910
- Testing
- Human chorionic gonadotropin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Oocyte Competence
Modulation Contrast Microscopy Imaging for Oocyte Quality Assessment
The present study aims to describe novel non-invasive parameters related to the competence of female reproductive cells (oocytes).
- Trial name
- NCT03683290
- Testing
- Image acquisition and analysis
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Center for Reproductive an Genetic Health
Infertility, Assisted Reproductive Technology
Does the Embryo Transfer Technique Affect the Success of in Vitro Fertilization?
Prospective, open, randomized, parallel, two-arm trial to compare the clinical pregnancy rate between most commonly used two embryo transfer techniques: trial followed by transfer technique and afterloading technique
- Conditions
- Infertility, Assisted Reproductive Technology, IVF
- Trial name
- NCT03756857
- Testing
- Afterload Transfer, Trial followed by transfer
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Acibadem Kadiköy Hospital
Anxiety, Assisted Reproductive Treatments
Virtual Reality for Anxiety Relief in Infertile Women
This study examines the impact of virtual reality (VR) applications on anxiety levels before and after embryo transfer procedures.
- Conditions
- Anxiety, Assisted Reproductive Treatments, Women, VR
- Trial name
- NCT07020975
- Testing
- VR Glasses
- Where
- Cyprus
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cyprus Aydin University
Infertility
Comparison of Crinone 8% Intravaginal Gel and IM Progesterone Supplementation for In Vitro Fertilization (IVF)
The goal of this research study is to compare the pregnancy rates for two different types of progesterone supplementation after in-vitro fertilization (IVF).
- Trial name
- NCT00656201
- Testing
- Crinone 8% Vaginal Gel, Intramuscular Progesterone
- Where
- United States
- Volunteers
- 468 people
- Sponsor
- Brigham and Women's Hospital
Clinical Pregnancy, Embryo Implantation
DNA Amplification in Blastocoel Fluid
Introduction: Although innovative procedural changes in frozen embryo transfer (FET) cycles have increased the implantation rate of blastocysts transferred significantly, blastocyst selection remains a significant limiting factor…
- Trial name
- NCT04744844
- Testing
- blastocoel fluid biopsy
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Antalya IVF
GnRH Antagonist IVF Protocol, Fresh Embryo Transfer
GnRH for Luteal Support - Mechanism of Action
This prospective observational study will include women undergoing IVF treatment with a GnRH antagonist protocol and fresh embryo transfer at the IVF unit of Shaare Zedek Medical Center.
- Conditions
- GnRH Antagonist IVF Protocol, Fresh Embryo Transfer, Administration of Hormonal Luteal Support
- Trial name
- NCT07620067
- Testing
- GnRH agonist, Progesterone
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Heli Alexandroni
IVF, Infertility
Improvement of Fertilization Rate and Embryo Quality by Treating Calcium Ionophore in IVF Patients: a Sibling Oocyte Control Study
GM508 CultActive is a bicarbonate buffered reagent and ready-to-use designed to investigate oocytes of patients with failed fertilization after previous Intracytoplasmatic Sperm Injection cycles.
- Conditions
- IVF, Infertility, Artificial Oocyte Activation
- Trial name
- GM508 in IVF (NCT05722067)
- Testing
- calcium ionophore
- Where
- Taiwan
- Volunteers
- 68 people
- Sponsor
- Chang Gung Memorial Hospital
Fertility Disorders
Assessment of the New Automated Vitrification System "GAVI" for Early Cleaved Embryos Cryopreservation
The meta-analysis comparing the cryopreservation of human embryos by vitrification or slow-freezing suggested that more well design studies as randomized trials are necessary to identify the most successful method for…
- Trial name
- GAVI (NCT03478592)
- Testing
- reference technique, vitrification technique
- Where
- France
- Volunteers
- 423 people
- Sponsor
- University Hospital, Toulouse
Infertility (IVF Patients)
Efficacy Study of the Embryo Transfer Catheter
A prospective randomized trial comparing Cook K-SOFT-5100 and Frydman classical catheter 4.5 for embryo transfer in human IVF/ICSI was performed.
- Trial name
- NCT00766714
- Testing
- Cook K-SOFT-5100 catheter, Frydman classical catheter
- Where
- Belgium
- Volunteers
- 1,446 people
- Sponsor
- University Hospital, Ghent
Infertility
Comparison of Two Embryo Transfer Catheters in Patients Undergoing in Vitro Fertilization and Embryo Transfer
In-vitro fertilization (IVF) treatment involves development of multiple follicles following ovarian stimulation, oocyte retrieval and embryo transfer (ET). ET is the final and most crucial step of IVF treatment.
- Trial name
- NCT02024880
- Testing
- Protective catheter group, Conventional catheter group
- Where
- China
- Volunteers
- 600 people
- Sponsor
- The University of Hong Kong
Embryo Implantation
Effect of Dilatation and Curettage on the Endometrial Receptivity
Effect of dilatation and curettage on the endometrial receptivity and pregnancy outcome in patients with recurrent implantation failure
- Trial name
- NCT03485235
- Testing
- D&C, ICSI
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Ain Shams University
Subfertility
GnRH Agonist for Dual Trigger in IVF and for Luteal Phase Support in FET
The objectives of this study are to compare the efficacy of the dual trigger group vs the hCG trigger group on the live birth rate in women undergoing IVF and the efficacy of the agonist in LP group vs the placebo group on the…
- Trial name
- NCT04064840
- Testing
- IVF: Decapeptyl and hCG, FET: Decapeptyl, IVF: hCG and normal saline
- Where
- China
- Volunteers
- 784 people
- Sponsor
- The University of Hong Kong
Embryo Disorder
Pilot Study: hCG Secreted by Blastocyst as Potential Marker of Embryo Quality
hCG is a hormone produced very early by the pre-embryo, but not by the oocyte. It has a pivotal role in the trophoblast differentiation, and embryo implantation as well as the corpus luteum support.
- Trial name
- NCT04736160
- Testing
- collect data
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- IVI Vigo
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.