Clinical trials: Endocrine Disorders
Type 1 Diabetes Mellitus, Diabetic Ketoacidosis
Diabetic Kidney Alarm (DKA) Study
The overarching goals of this study are to determine whether tubular dysfunction (elevated urine sodium, bicarbonate and amino acids) and injury (elevated kidney injury molecule 1 [KIM-1], neutrophil gelatinase-associated…
- Trial name
- DKA (NCT03128229)
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Colorado, Denver
Hypoparathyroidism, Chronic Hypoparathyroidism
Efficacy, Safety, and Tolerability of Encaleret in Participants With Chronic Hypoparathyroidism
The aim of the study is to evaluate the efficacy, safety, and tolerability of orally administered encaleret tablets in participants with chronic hypoparathyroidism (HP).
- Trial name
- RECLAIM-HP (NCT07805356)
- Testing
- Encaleret
- Where
- 5 sites in United States, Canada
- Volunteers
- 160 people
- Sponsor
- Calcilytix Therapeutics, Inc., a BridgeBio company
Ovarian Cancer, Primary Peritoneal Cavity Cancer
Combination Chemotherapy in Treating Patients With Primary Peritoneal or Stage III Epithelial Ovarian Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and giving drugs in different ways may kill more tumor cells.
- Trial name
- NCT00003322
- Testing
- cisplatin, paclitaxel, quality-of-life assessment
- Where
- 67 sites in United States, Canada
- Volunteers
- 384 people
- Sponsor
- Gynecologic Oncology Group
Growth Hormone Deficiency
Crossover Study to Assess the Safety and Pharmacokinetic of Pegylated Somatropin(PEG Somatropin) in GHD Children
The purpose of the phase 1 study is to assess the safety and pharmacokinetics of PEG somatropin, which administered once per week, compared with the daily used somatropin, and to evaluate the safety and possibility to replace…
- Trial name
- Phase 1 (NCT01613573)
- Testing
- somatropin AQ, pegylated somatropin
- Volunteers
- 12 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Gestational Diabetes
Remote Monitoring of Diabetes in Pregnancy: a Feasibility Study
When women with diabetes become pregnant it is particularly important to control blood sugar levels to prevent complications. Women are advised to test their blood glucose levels seven times a day and to attend antenatal and…
- Trial name
- Tele-Mum (NCT01630759)
- Testing
- Telemonitoring, Control
- Where
- 2 sites in Ireland, United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Ulster
Diabetes
Continuous Monitoring and Control of Hypoglycemia
Evaluate safety of non-adjunctive CGM use in CGM naive participants.
- Trial name
- COACH (NCT03340831)
- Testing
- Continuous Glucose Monitoring (CGM)
- Where
- 25 sites in United States
- Volunteers
- 1,388 people
- Sponsor
- DexCom, Inc.
Obesity, Hyperandrogenemia
Effect of Metformin on Adrenal or Ovarian Androgen Production in Overweight Pubertal Girls With Androgen Excess
This study will test whether metformin administration can ameliorate androgen (male hormone) overproduction in overweight pubertal girls with androgen excess.
- Conditions
- Obesity, Hyperandrogenemia, Polycystic Ovary Syndrome
- Trial name
- NCT01422746
- Testing
- Metformin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Virginia
Type 1 Diabetes Mellitus, Hypoglycemia
FreeStyle Libre FGM During Summer Camp for Children With Type 1 Diabetes
A randomized, double-blinded, single center, parallel design pediatric study, on 45 subjects with type 1 diabetes (T1D), aged six to 15 (inclusive) years, measuring sensor time in glucose values within range 3.9 - 10 mmol/l (70 …
- Conditions
- Type 1 Diabetes Mellitus, Hypoglycemia, Hyperglycemia
- Trial name
- NCT03182842
- Testing
- FreeStyle Libre FGM, SMBG - Blinded Sensor
- Where
- Slovenia
- Volunteers
- 45 people
- Sponsor
- University of Ljubljana, Faculty of Medicine
Diabetes
CSII Pilot in Adolescents With Type 2 Diabetes
This feasibility pilot is intended to understand whether adolescents with Type 2 Diabetes (2DM) can be transitioned to a continuous subcutaneous insulin injection (CSII) and if so, assess whether CSII is a feasible treatment…
- Trial name
- NCT02748122
- Testing
- MMT 723
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- NYU Langone Health
Diabetes Mellitus, Type 1, Diabetes Complications
Children With Diabetes at Risk for Heart Disease.
Patients with type 1 diabetes type 1 (DM1) have increased risk of death due to heart disease and stroke. These cardiovascular conditions (CVD) are the leading cause of death in patients with DM1 younger than 40 years of age and…
- Trial name
- NCT02275091
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Polycystic Ovary Syndrome, Non-Alcoholic Fatty Liver Disease
NAFLD in Adolescents and Young Adults With PCOS
This project focuses on an at-risk adolescent and young adult population who may gain long-term health benefits from detection of risk factors at a young age.
- Conditions
- Polycystic Ovary Syndrome, Non-Alcoholic Fatty Liver Disease, Metabolic Syndrome
- Trial name
- NCT02506946
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Columbia University
Huntington Disease, Hereditary Breast and Ovarian Cancer
Genetic Risk: Whether, When, and How to Tell Adolescents
This study is being conducted to learn more about family communication of genetic risk information. Semi-structured interviews lasting up to one hour will be conducted with three populations: parent/child pairs at risk for…
- Conditions
- Huntington Disease, Hereditary Breast and Ovarian Cancer, Hereditary Cancer, Hereditary Non-polyposis Colon Cancer
- Trial name
- NCT03421327
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Growth Hormone Deficiency
Isolated Growth Hormone Deficiency and Amennorrhea
This is a case report of a 14-year old female with no menstruation history.
- Trial name
- NCT05448924
- Testing
- Hormone panel tests
- Where
- Indonesia
- Volunteers
- 1 people
- Sponsor
- Universitas Padjadjaran
Diabetes Mellitus, Covid19
Clinical Phenotype and Outcomes of Inpatients With COVID-19 and Diabetes
Patients with diabetes have been listed as people at higher risk for severe illness from COVID-19. Moreover, the relationship between diabetes-related phenotypes and the severity of COVID-19 remains unknown.
- Trial name
- NCT04550403
- Where
- Italy
- Volunteers
- 757 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Chronic Kidney Diseases, Chronic Kidney Disease-Mineral and Bone Disorder
Chinese CKD-MBD Prevalence Survey (CRISS-MBD)
This is a multi-center cross sectional epidemiological study. The purpose of this study is to investigate the prevalence of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD) in Chinese population.
- Trial name
- NCT04714918
- Where
- 40 sites in China
- Volunteers
- 10,254 people
- Sponsor
- Limeng Chen
Unilateral Cryptorchidism
Orchidopexy Randomized Clinical Assessment
This is a randomized trial designed to evaluate testicular outcomes after a single stage versus a two-stage surgical procedure to fix an undescended, one-sided testicle located in the abdomen.
- Trial name
- ORCA (NCT02235623)
- Testing
- Single-stage Fowler-Stephens orchidopexy (FSO), Two-stage Fowler-Stephens orchidopexy (FSO)
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Boston Children's Hospital
Diabetes Mellitus, Type 1
AbATE Follow-Up Study
This study proposes to conduct a non-interventional, multi-center trial that will look at C-peptide results from one or two Mixed Meal Tolerance Tests (MMTT) in participants who received anti-CD3 treatment or placebo on the Abate…
- Trial name
- NCT02067923
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Yale University
Fertility Disorders, Turner Syndrome
The Danish TURNER Cryopreservation Study
The goal of this clinical trial is to investigate if cryopreservation of ovarian tissue in girls with Turner syndrome can improve their fertility and lead to increased number of liveborn babies of Turner syndrome mothers.
- Conditions
- Fertility Disorders, Turner Syndrome, Premature Ovarian Failure
- Trial name
- DANTE (NCT05740579)
- Testing
- laparoscopic cryopreservation of one ovary
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Cancer
Laboratory Assay in Determining Cancer Resistance in Patients With Metastatic Cancer and in Healthy Participants
RATIONALE: Studying samples of blood and tissue in the laboratory from patients with cancer and from healthy participants may help doctors learn more about cancer.
- Trial name
- NCT00899496
- Testing
- immunological diagnostic method, physiologic testing
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Ovarian Cysts, Pediatric ALL
Management of Ovarian Masses in Pediatric Patients: an Italian Survey
Objectives: The International Ovarian Tumor Analysis (IOTA) provides a specific terminology for adult ovarian masses, while, currently, there is no systematic classification for preoperative assessment of adnexal lesions in…
- Conditions
- Ovarian Cysts, Pediatric ALL, Diagnosis
- Trial name
- OvaMa-PEDs (NCT05800613)
- Testing
- Survey
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.