Clinical trials: Executive Function Disorders
Attention Deficit Hyperactivity Disorder
The Association Between Executive Functions and Candidate Genes of Dopaminergic and Noradrenergic Systems in Attention Deficit Hyperactivity Disorder (ADHD)
The ultimate goal of this study is to find specific polymorphism of candidate genes (particularly of dopaminergic and noradrenergic systems) associated with intermediate phenotypes (e.g., executive functions, IQ, and other…
- Trial name
- NCT01052753
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder, Attention Deficit-Hyperactivity Disorder
Community Based Intervention for Children With ADHD and ASD
The purpose of this study is to determine whether a new treatment, Unstuck and On Target (UOT), works better, worse, or the same as the best treatment that is available now, Contingency Behavioral Management (CBM), for low income…
- Conditions
- Autism Spectrum Disorder, Attention Deficit-Hyperactivity Disorder, Executive Function
- Trial name
- NCT03003286
- Testing
- Unstuck and on Target (UOT), Parents and Teachers Supporting Students (PATSS)
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Lauren Kenworthy
Disruptive Mood Dysregulation Disorder, Attention Deficit Hyperactivity Disorder
Symptoms and Mechanisms of Child Psychiatric Disorders
In this study the investigators will examine psychiatric symptoms, central neurocognitive functions, parental stress and attachment styles, and biological factors that can give new knowledge about some of the mechanisms present…
- Conditions
- Disruptive Mood Dysregulation Disorder, Attention Deficit Hyperactivity Disorder, Oppositional Defiant Disorder, Severe Irritability
- Trial name
- NCT05049356
- Where
- 2 sites in Norway
- Volunteers
- 218 people
- Sponsor
- Oslo University Hospital
Obesity, Type 2 Diabetes Prevention
The Medical College of Georgia PLAY Project: Exercise Dose and Insulin Sensitivity in Obese Children
The study is a behavioral clinical trial of aerobic exercise to determine dose-response effects on risk for type 2 diabetes, fatness, fitness, blood cholesterol levels, and other cardiovascular risk factors in overweight…
- Conditions
- Obesity, Type 2 Diabetes Prevention, Executive Function (Cognition)
- Trial name
- NCT00108901
- Testing
- Aerobic exercise program
- Where
- United States
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Developmental Language Disorder
Training Inner Speech in Children With Developmental Language Disorder
The complex and unclear relationship between language and executive function (EF) creates barriers to developing effective interventions for children with developmental language disorder (DLD) whose language difficulties often…
- Trial name
- NCT06880731
- Testing
- Modeling with Verbal Mediation, Modeling Only
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- MGH Institute of Health Professions
Dyslexia, Executive Dysfunction
The Effects of Play and Competition-Based Cognitive Therapy
Purpose: The aim of this study was to investigate the effects of play and competition-based cognitive therapy (PCB-CT) on executive function and occupational routines in children with dyslexia.
- Trial name
- NCT03906097
- Testing
- Play and Competition-Based Cognitive Therapy
- Volunteers
- 64 people
- Sponsor
- Hacettepe University
Mild Cognitive Impairment
Making Memory Better for Seniors With Mild Cognitive Impairment
The purpose of this study is to investigate the feasibility and effectiveness of a cognitive training group in individuals with Mild Cognitive Impairment, using a new paradigm that will optimize ecological validity by (1)…
- Trial name
- NCT01532739
- Testing
- Cognitive training
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Nova Scotia Health Authority
Attention Deficit Hyperactivity Disorder (ADHD), ADHD
Effects of Phosphatidylserine and DHA on Cognitive Performance in Children With ADHD
This study aimed to evaluate the effects of different phosphatidylserine (PS) formulations, with or without docosahexaenoic acid (DHA), on cognitive performance in children diagnosed with attention-deficit/hyperactivity disorder…
- Trial name
- PS-DHA-ADHD (NCT07521449)
- Testing
- Phosphatidylserine-Omega3, DHA Omega-3
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Çağlar Charles Daniel Jaicks
Autism, Autism Spectrum Disorder
Improving Academic and Social Functioning in Middle-Schoolers With Autism
The goal of this study is to test how well two group interventions work for middle-school children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT06705907
- Testing
- Achieving Independence and Mastery in School (AIMS), Building Essential Social Skills for Teens (BESST)
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Childhood Cancer, Cancer-related Problem/Condition
Effect of Cognitively Challenging Physical Activity on Executive Functions in Pediatric Cancer Patients
When it comes to exercise and sport for children and adolescents with cancer, there is often still the opinion that physical activity has a negative effect on the weakened body suffering from cancer.
- Conditions
- Childhood Cancer, Cancer-related Problem/Condition, Cognitive Side Effects of Cancer Therapy, Physical Activity
- Trial name
- KiKli Fit (NCT06839794)
- Testing
- Cognitively challenging physical activity for paediatric cancer patients, Physical activity recommendations
- Where
- Switzerland
- Volunteers
- 70 people
- Sponsor
- University of Bern
Primary Brain Tumor, Neurocognition
Executive and Socio-cognitive Functions in Survivors of Primary Brain Tumor: Impact on Patients' Quality of Life
Significant advances in primary malignant brain tumors (PBT) treatment have led to dramatically improved survival, both in children and adults.
- Conditions
- Primary Brain Tumor, Neurocognition, Quality of Life
- Trial name
- NEUROCOG-QOL (NCT02693405)
- Testing
- Executive functions, social cognition, quality of life
- Where
- France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
School Readiness, Developmental Delays
Early Intervention Foster Care: A Prevention Trial
The Early Intervention Foster Care [EIFC] project is an efficacy trial of the Oregon Social Learning Center Multidimensional Treatment Foster Care Program, a preventive intervention that targets 3 commonly co-occurring variables…
- Trial name
- EIFC (NCT00701194)
- Testing
- Early Intervention Foster Care (EIFC)
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- Oregon Social Learning Center
Healthy Volunteer
Effects of Interrupting Sedentary Behavior on Metabolic and Cognitive Outcomes in Children
Background: Some studies in adults have found that insulin and glucose blood levels are lower when a long period of sitting is broken up with walking, compared to sitting without breaks.
- Trial name
- NCT01888939
- Testing
- Walking on a Treadmill, Sedendary Activities Only
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
ADHD, Child, Only
A Randomized Controlled Study of Family Based EF Training for Schoolage Children With ADHD
The goal of this study is to provide a new treatment approach for schoolage children with ADHD, which could facilitate the EF developing well to achieve better outcome.
- Trial name
- NCT05025501
- Testing
- Family based Executive Function Training
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Executive Function Disorder, Obesity, Childhood
The Purpose of This Research is to Investigate the Effects of Aerobic Exercise on Executive Function in Obese Children
The goal of this clinical trial is to learn if aerobic exercise improves executive functioning in obese children. It will also understand the effects of aerobic exercise on executive functioning in obese children.
- Trial name
- NCT06510920
- Testing
- Aerobic exercise
- Where
- China
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Jing Xin
Autism Spectrum Disorder
Effects of Systematic Exercise Training on Core Symptoms, Executive Function and Brain Function in Children With ASD
Studies have shown that children with ASD simultaneously have deficits in overall executive function and impairments in basic motor skills, which have a negative impact on cognitive and social all-round development.
- Trial name
- NCT07104708
- Testing
- The Child-Parent- Trainer exercise program, The regular physical training
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Chen Li
22Q11 Deletion Syndrome, tACS
Using Transcranial Alternating Current Stimulation to Improve Executive Function in 22q11.2 Deletion Syndrome
The purpose of this project is to explore the effects of transcranial alternating current stimulation (tACS) in children, adolescents and young adults with a 22q11.2 microdeletion.
- Trial name
- NCT05664412
- Testing
- at-home tACS using Starstim-Home tES
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Stephan Eliez
Executive Functions in Cerebral Palsy
Personalized Innovative Intervention Pathways to Promote EF in Children With CP
Cerebral palsy (CP) is an umbrella term, covering a group of disorders of movement and posture. It is now accepted that CP represents much more than a disorder of movements considering the frequent association with a broad range…
- Trial name
- NCT06288971
- Testing
- Self-adaption web-based software for the rehabilitation of EF and visuo-spatial abilities, Tele-rehabilitation of EF and specific cognitive processes underlying academic skills, Game-based tools for the rehabilitation of EF and motor planning
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- IRCCS Fondazione Stella Maris
Congenital Heart Defect, Executive Function
Improving Neurodevelopmental Outcomes in Children With Congenital Heart Disease: An Intervention Study
Each year, approximately 1 child in every 100 is born with Congenital Heart Disease (CHD), making it the most common birth defect.
- Conditions
- Congenital Heart Defect, Executive Function, Children, Neurodevelopmental Disorders
- Trial name
- NCT03023644
- Testing
- Cogmed Working Memory Training
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Boston Children's Hospital
ADHD, Executive Function
Effectiveness of the Indonesian Computer-based Game
The aim of this study was to develop an Indonesian computer-based game prototype that targets the clinical symptoms of ADHD as well as executive function and to investigate effectiveness through fMRI BOLD examination.
- Trial name
- NCT04329663
- Testing
- Indonesian computer-based game prototype
- Where
- Indonesia
- Volunteers
- 10 people
- Sponsor
- Tjhin Wiguna