Clinical trials: Extremity
Apnea of Prematurity, Hypoxia
Non-invasive Intervention for Apnea of Prematurity
Purpose of Study: Apnea of Prematurity (AOP) is common, affecting the majority of infants born <34 weeks gestational age (GA). Apnea is accompanied by intermittent hypoxia (IH), which contributes to multiple pathologies…
- Conditions
- Apnea of Prematurity, Hypoxia, Bradycardia
- Trial name
- NCT02641249
- Testing
- Vibration
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- University of California, Los Angeles
Cerebral Palsy, Hemiplegia
Functional Benefits of Multisite Upper Limb Surgery in Children With Unilateral Cerebral Palsy (RETRO-CHIRc)
This retrospective study evaluates the functional impact of individualized multisite neuro-orthopedic upper limb surgery in children with unilateral cerebral palsy (hemiplegic CP).
- Trial name
- RETRO-CHIRc (NCT07891078)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française
Cystic Fibrosis
Upper Extremity Exercise Capacity, Muscle Oxygenation, Balance in Patients With Cystic Fibrosis
The primary aim of the study is to evaluate upper extremity exercise capacity, muscle oxygenation, balance and physical activity level in patients with cystic fibrosis..
- Trial name
- NCT04803643
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
Deformity of Limb
Study of Infantile Lower Limb Malformations and Deformities
The skeletal defects of the lower limbs in pediatric age encompass various congenital and acquired conditions that alter bone structure.
- Trial name
- REMEDIA-I (NCT06519175)
- Testing
- Conservative treatment, Single or multi-stage surgery, Amputation
- Where
- 7 sites in Italy
- Volunteers
- 1,000 people
- Sponsor
- Istituto Ortopedico Rizzoli
Dysferlinopathy, LGMD2B Now Classified as LGMDR2
Clinical Outcome Study for Dysferlinopathy
The "Clinical Outcome Study for Dysferlinopathy" is being performed in centres in Europe (UK- Newcastle; Spain- Barcelona, Sevilla; San Sebastian;Denmark, Copenhagen, Italy- Padova; France- Paris,), USA (Charlotte, NC; Columbus…
- Conditions
- Dysferlinopathy, LGMD2B Now Classified as LGMDR2, Miyoshi Myopathy
- Trial name
- Jain COS (NCT01676077)
- Where
- 16 sites in United States, Chile and 7 more
- Volunteers
- 200 people
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
Leg Length Inequality, Foot Deformities
Botox Clinical Trial
The surgery to correct leg \& foot deformities in children is a lengthy, \& sometimes, difficult procedure. Metal frames are attached to the leg and / or foot and over a period of time the frame is manipulated to obtain the…
- Trial name
- NCT00624299
- Testing
- Botox, Saline
- Where
- United Kingdom
- Sponsor
- Sheffield Children's NHS Foundation Trust
Ulnar Longitudinal Deficiency, Ulnar Hand Deformity
Longitudinal Ulnar Deficit (ULNEER)
The management of patients with longitudinal ulnar deficiency is a clinical challenge due to the rarity of this condition and the wide variety of its manifestations.
- Trial name
- ULNEER (NCT07404514)
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Hopitaux de Saint-Maurice
Clubfoot, Telemedicine
MiracleFeet Foot Abduction Brace Sensor Trial
The aim of this study is to determine the effect of a new design of FAB type on compliance and treatment outcomes of idiopathic clubfeet treated by the Ponseti method.
- Conditions
- Clubfoot, Telemedicine, Patient Compliance
- Trial name
- mFAB (NCT03249805)
- Testing
- Steenbeek Foot Abduction Brace (SFAB), MiracleFeet Foot Abduction Brace (mFAB)
- Where
- India
- Volunteers
- 80 people
- Sponsor
- MiracleFeet
Pes Planus, Flatfoot
Medial Arch-Support Wrestling Shoes and Foot Posture Preservation in Adolescent Wrestlers
This three-year randomized controlled trial investigated whether wrestling shoes with built-in medial arch support can preserve foot arch structure in adolescent male wrestlers compared to standard wrestling shoes without arch…
- Conditions
- Pes Planus, Flatfoot, Foot Deformities
- Trial name
- MAWS-RCT (NCT07632924)
- Testing
- Medial Arch-Support Wrestling Shoe, Standard Wrestling Shoe
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Inonu University
Parkinson Disease
Robotic Rehabilitation of Upper Limb in PD
It has been shown that robot-assisted therapy may be considered an effective and reliable method for the delivery of highly repetitive training useful to boost neuroplasticity.
- Trial name
- NCT03893786
- Testing
- Robotic Rehabilitation
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Sport Injury, Osteoarthritis, Knee
Biometric Recognition and Rehabilitation Assessment of Lower Extremity Sports Injury Based on Gait Touch Information
The current common clinical methods cannot truly reflect the biomechanical status of the knee joint. Based on the foot-knee coupling mechanism, the simple and practical dynamic gait touch information provided by the 3D force…
- Trial name
- NCT04462913
- Testing
- no intervention
- Where
- China
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Resistance Training, Inter-limb Asymmetries
Evaluation of Physical Performance and Functional Asymmetries in Female Football
Worldwide, soccer has grown increasingly popular among female players. According to the Women´s Football Survey of the Fédération Internationale de Football Association (FIFA), there were more than 30 million registered women…
- Conditions
- Resistance Training, Inter-limb Asymmetries, Athletic Performance
- Trial name
- NCT03862560
- Testing
- Strength training program
- Where
- Spain
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
COVID, Corona Virus Infection
RIC as an Adjunct Therapy for Severe COVID-19 Disease: a Prospective Randomized Pilot Study
This research aims to assess the use of an experimental and non-invasive procedure, Remote Ischemic Conditioning (RIC), as an adjunct therapy in attenuating severe COVID-19 disease.
- Conditions
- COVID, Corona Virus Infection, Acute Lung Injury, Ischemia Limb
- Trial name
- NCT04659460
- Testing
- Remote Ischemic Conditioning
- Volunteers
- 30 people
- Sponsor
- Unity Health Toronto
Melanoma
A Randomized Phase III Trial of Hyperthermic Isolated Limb Perfusion With Melphalan, Tumor Necrosis Factor, and Interferon-Gamma in Patients With Locally Advanced Extremity Melanoma
Randomized study. Initially, 3 patients will be entered on Arm I as a pilot feasibility study and to standardize the technical aspects of the study. Subsequently, all patients are randomized to Arms I and II.
- Trial name
- NCT00001296
- Testing
- melphalan, tumor necrosis factor, interferon-gamma
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- National Cancer Institute (NCI)
Sports Physical Therapy
Upper Extremity Performance, Balance and Core Endurance in Adolescent Soccer Players
Soccer is one of the most popular sports in the world with a large number of players under the age of 18. High physical demands, frequent changes in exercise intensity and a large number of movement profiles require optimal…
- Trial name
- NCT06671080
- Testing
- Closed Kinetic Chain Upper Extremity Stability Test
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Biruni University
Cerebral Palsy, Upper Extremity Problem
Effects of Action Observation Therapy and Video-Based Play Therapy on Children With Unilateral Cerebral Palsy
Cerebral Palsy (CP) defines a group of permanent disorders in the development of movement and posture, which occur in the developing fetal and newborn brain, due to non-progressive disorders, leading to activity limitations.
- Trial name
- NCT05327179
- Testing
- Action Observation Treatment, Virtual Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Sinem Erturan
Cerebral Palsy
Evaluation the Feasibility and Effects of Kinect-based Computer Games as UE Training Tool in Cerebral Palsy Children
The purpose of this study is to design and evaluation the feasibility, effects of Kinect-based Computer Games as Upper Extremity Training Tool in Children with Cerebral Palsy.
- Trial name
- NCT02364245
- Testing
- Kinect, Traditional OT(30 Mins), Traditional OT(60 Mins)
- Where
- Taiwan
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Spastic Cerebral Palsy
INcobotulinumtoxina in ChIldren Upper and Lower Limb sPasticITy (INCIPIT)
Prospective, open-label, non-randomized, single-arm, dose titration, phase II study. The study will consist of three injection cycles. In each, an injection visit is followed by an observation period of 12 to 20 weeks.
- Trial name
- INCIPIT (NCT05340439)
- Testing
- IncobotulinumtoxinA 100 UNT [Xeomin]
- Volunteers
- 30 people
- Sponsor
- Universita di Verona
Cerebral Palsy
Scapular Alignment and Upper Limb Function in Children With Cerebral Palsy
Purpose: To determine the effect of scapular alignment on upper limb function in hemiparetic children and to find relation between scapular alignment of the affected, less affected limb and the upper limb function in children…
- Trial name
- Hemiparesis (NCT04644588)
- Testing
- Children with hemiparetic cerebral palsy being assessed for scapular alignment and upper limb function.
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Migraine
Safety and Tolerability of Frovatriptan to Prevention of Menstrually Associated Migraine (MAM) Headaches
In this open-label, multi-center study, patients were treated with frovatriptan for a maximum of 12 perimenstrual periods (PMPs).
- Trial name
- MAM (NCT01035983)
- Testing
- Frovatriptan 2.5 mg
- Where
- 5 sites in Germany, Hungary and 3 more
- Volunteers
- 550 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
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