Clinical trials: Extremity
Hernia, Inguinal, Flat Foot
The Efficacy and Safety of Chloroprocaine 1% and 2% in Pediatric Population
Randomized, multi-center, double-blind, two-armed, parallel active groups, prospective trial to evaluate the efficacy and safety of local anesthetic Chloroprocaine at two different concentrations ( at 1% and 2%) in a pediatric…
- Trial name
- NCT03918798
- Testing
- Chloroprocaine 1% Injectable Solution, Chloroprocaine 2% Injectable Solution
- Where
- 9 sites in Italy, Spain
- Volunteers
- 164 people
- Sponsor
- Sintetica SA
Child Development, Upper Motor Neurone Lesion
Validity and Reliability of the PROprioception Measurement Tool (PROMT)
This project assesses the feasibility, reliability, and validity of the PROMT in children with a UMN lesion. The study questions are: is the newly developed PROMT a feasible, reliable, and valid tool to assess lower limb…
- Conditions
- Child Development, Upper Motor Neurone Lesion, Cerebral Palsy, Proprioceptive Disorders
- Trial name
- PROMT (NCT05405881)
- Testing
- Proprioception measurement tool
- Where
- Switzerland
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Flat Foot, Lateral Column Lengthening
Evaluation of the Titan 3-D™ Wedge System
Evaluate clinical healing and radiographic maintenance of correction following an LCL procedure or medial cuneiform osteotomy (Cotton) at 6 months following the use of the TITAN 3-D™ Wedge.
- Conditions
- Flat Foot, Lateral Column Lengthening, Medial Cuneiform Osteotomy
- Trial name
- NCT03421665
- Testing
- Titan 3D Wedge System
- Sponsor
- Paragon 28
Sarcoma
Tissue Sample Collection From Patients With Soft Tissue Sarcoma of the Arms, Hands, Legs, or Feet Treated on Clinial Trial CRUK-VORTEX
RATIONALE: Collecting and storing samples of tumor tissue from patients with soft tissue sarcoma to test in the laboratory may help the study of cancer in the future.
- Trial name
- NCT00900211
- Testing
- microarray analysis, molecular diagnostic method, biologic sample preservation procedure
- Where
- 12 sites in United Kingdom
- Volunteers
- 400 people
- Sponsor
- The Christie NHS Foundation Trust
Elastic Band Exercises, Blood Flow Restrictive Exercises, Tennis
Elastic Band Exercises With Blood Flow Restriction Technique in Tennis Players
Considering that therabant (elastic band) training combined with blood flow restriction exercises can be an effective training program for achieving muscle hypertrophy in practical applications, the aim of this study was to…
- Trial name
- NCT07676071
- Testing
- Blood flow restricts exercise, Elastic band exercises without occlusion
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Akdeniz University
Congenital Limb Anomaly Nos
Congenital Hand and Upper Extremity Malformations
Getting the incidence of upper limb anomalies in our department from 2000 to 2020 and classifying them using IFSSH classification and OMT classification
- Trial name
- NCT05182333
- Testing
- Examination
- Volunteers
- 100 people
- Sponsor
- Assiut University
Cerebral Palsy, Pes Planus
The Effect of Kinesio Taping on q Angle and Pes Planus in Children With Cerebral Palsy
The aim of our study is to examine the effect of using kinesiology tape and using it for 8 weeks on Q angle and pes planus on children with cerebral palsy.
- Trial name
- NCT06004271
- Testing
- exercise, exercise and taping
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Uskudar University
Breast Cancer Lymphedema, Post-Mastectomy Secondary Lymphedema
New Therapeutic Approach in Upper Limb Lymphedema Secondary to Breast Cancer: Activity-oriented Proprioceptive Antiedema Therapy (TAPA)
This study evaluates the effectiveness of an experimental proposal therapy for upper limb lymphedema secondary to breast called Activity-oriented proprioceptive antiedema therapy (TAPA) facing the consensual gold standard…
- Trial name
- NCT03762044
- Testing
- Activity-oriented Proprioceptive Antiedema Therapy (TAPA), Complete Decongestive Therapy (CDT)
- Where
- Spain
- Volunteers
- 51 people
- Sponsor
- Hospital Universitario Reina Sofia de Cordoba
Cerebral Palsy Spastic Diplegia
Neck-Trunk Stabilization Exercises and Bobath Therapy Spastic Diplegic Cerebral Palsy
Physiotherapy is widely used in the treatment of children with cerebral palsy. This study is conducted to identify the most appropriate physiotherapy approach.
- Trial name
- NCT05707052
- Testing
- Neck-Trunk Stabilization Exercises and conventional physical therapy, Bobath Therapy and conventional physical therapy
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Wound, Diabetes
Pathology of Skin, Nerve and Vasculature in the Amputated Limb of Diabetes
1. To explore the pathology of nerve, vascular, and skin in the amputated leg 2. To diagnose small-fiber sensory neuropathy of the contralateral leg by investigating the skin intervention 3.
- Conditions
- Wound, Diabetes, Amputation
- Trial name
- NCT00840164
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Pain
Comparison of Acetaminophen With Codeine and Ibuprofen for Children With Injuries
We compared the pain relief of acetaminophen with codeine versus ibuprofen for children ages 5-18 years who came to the Pediatric Emergency Department with injuries to their arms or legs.
- Trial name
- NCT00474721
- Testing
- ibuprofen, acetaminophen with codeine
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of California, San Diego
Spastic Hemiplegic Cerebral Palsy
Progressive Functional Strength Training in Unilateral Spastic Cerebral Palsy
This study is aimed to investigate effectiveness of progressive functional strength training protocol (functional squat system with virtual reality in leg press, plyometric exercises, exercises with Bosu ball \& heel-rise…
- Trial name
- NCT02460406
- Testing
- traditional physiotherapy, progressive functional strength training
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Hacettepe University
Diagnostic Imaging, Tomography, X Ray Computed
Photon Counting Detector CT Image Quality
This study aims to compare subjective image quality and diagnostic accuracy of a photon counting detector computed tomography (PCD-CT) scanner compared with an energy integrating detector (EID)-CT scanner as the reference…
- Trial name
- NCT06281808
- Testing
- Photon Counting Detector CT
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Reto Sutter, MD
Sarcoma of Pelvis
Isolated Pelvic and Limb Perfusion in the Treatment of Locally Advanced Sarcoma of Pelvis and Limbs' Girdle
This study looks at isolated pelvic perfusion and limbs' girdle with 1 mg tumor necrosis factor alpha (TNFa) in the treatment of locally advanced sarcoma of the pelvis and limbs' girdle.
- Trial name
- NCT00181025
- Testing
- Tasonermine (TNFa), Melphalan
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Pareses, Lower Extremity
C-Brace Prospective Registry
To gather prospective safety and effectiveness data for the C-Brace System following the standard of care.
- Trial name
- NCT04640584
- Testing
- C-Brace
- Where
- 76 sites in United States, Australia and 2 more
- Volunteers
- 250 people
- Sponsor
- Otto Bock Healthcare Products GmbH
Muscular Dystrophy, Duchenne, Upper Extremity
The Effects of Trunk Exercises on Upper Extremity and Respiratory Functions in DMD
The aim of this study was to investigate the effects of trunk training on trunk control, upper extremity, and pulmonary function in children with Duchenne muscular dystrophy (DMD).
- Conditions
- Muscular Dystrophy, Duchenne, Upper Extremity, Respiratory Functions
- Trial name
- NCT04669847
- Testing
- Trunk-oriented exercise program, Conventional exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Gokce Yagmur Gunes Gencer
Hypochondroplasia
An Interventional Study of Infigratinib in Children With Hypochondroplasia
ACCEL2/3 is a Phase 2/3 study. The purpose of the Phase 2 portion of the study (ACCEL2/3) is to evaluate the efficacy and safety of infigratinib in children with hypochondroplasia (HCH) receiving infigratinib at one of two doses…
- Trial name
- HCH (NCT06873035)
- Testing
- infigratinib 0.128 mg/kg/day, infigratinib 0.25 mg/kg/day
- Where
- 24 sites in United States, Australia and 8 more
- Volunteers
- 24 people
- Sponsor
- QED Therapeutics, a BridgeBio company
Amelia, Femur Fibula Ulna Syndrome
Methylome Study in Sporadic Limb Malformations
Some limb malformations are known to be sporadic (non hereditary). For these malformations, no molecular cause was identified, even after whole genome sequencing.
- Trial name
- METHYLIMB (NCT05555225)
- Testing
- Methylome
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Cerebral Palsy
A Trial Comparing Two Methods of CIMT in the Hemiplegic Child
Cerebral palsy remains a major cause of lifelong disability affecting approximately 2 per 1,000 children. Of those about 30% have hemiplegic cerebral palsy (HPC),a unilateral impairment, which can often lead to major difficulties…
- Trial name
- HCPCIMT (NCT01770678)
- Testing
- Constraint Induced Movement Therapy
- Volunteers
- 62 people
- Sponsor
- University of Birmingham
Failed Back Surgery Syndrome, Limb Ischemia
Evaluation of Online Tool (E-TOOL SCS) in Spinal Cord Stimulaion
This observational multicenter study aims to evaluate the reliability and validity of the e-tool for selecting patients eligible for SCS for chronic pain caused by one of the four etiologies listed above in the experience of…
- Conditions
- Failed Back Surgery Syndrome, Limb Ischemia, Neuropathic Pain, Complex Regional Pain Syndromes
- Trial name
- E-TOOLSCS (NCT06229015)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
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