Clinical trials: Extremity
Cerebral Palsy, Rehabilitation
Video-Based Games for Upper Limb Rehabilitation in Cerebral Palsy
The aim of the present study is to compare the effects of Neurodevelopmental Treatment (NDT)-based upper limb rehabilitation and video-game based therapy (VGBT) with Nintendo® Wii and LMC games on upper extremity functions in…
- Trial name
- NCT03622970
- Testing
- VGBT with Nintendo® Wii and LMC games, NDT-based upper limb rehabilitation
- Volunteers
- 30 people
- Sponsor
- Istanbul University
Cerebral Palsy, Hemiplegia
tDCS and Robotic Training in Adults With Cerebral Palsy
The purpose of this study is to improve arm function in adults with hemiplegic cerebral palsy. Participants will receive transcranial direct current stimulation (or sham) in combination with upper extremity robotic therapy.
- Trial name
- NCT03038269
- Testing
- Upper Extremity Robotics, tDCS
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Burke Medical Research Institute
Diabetes Mellitus
Assessing Diabetic Foot Ulcer Microcirculation With High-frequency Contrast Enhanced Ultrasound
The objective of this observational study is to investigate and validate the utility of high-frame-rate ultrasound imaging technology for dynamic observation of the blood perfusion process at the site of ulcer wounds in…
- Trial name
- NCT06309082
- Testing
- Amputation, Debridement
- Where
- China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
for Upper Limb Soft Tissue Coverage
The Radial Forearm Flap In Reconstruction Of Upper Limb Injuries
The radial forearm flap is a very useful and versatile flap with a long vascular pedicle and a thin, pliable skin. It's used in reconstruction of the mutilated hand as a reverse pedicled flap.
- Trial name
- NCT06319586
- Testing
- Radial Forearm Flap
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sohag University
Diagnostic Imaging, Tomography, X Ray Computed
Photon Counting Detector CT Image Quality
This study aims to compare subjective image quality and diagnostic accuracy of a photon counting detector computed tomography (PCD-CT) scanner compared with an energy integrating detector (EID)-CT scanner as the reference…
- Trial name
- NCT06281808
- Testing
- Photon Counting Detector CT
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Reto Sutter, MD
Spinal Muscular Atrophy, Assessment, Self
Development of a Space Exploration Assessment for Children With Spinal Muscular Atrophy
The aim of this randomized study is to develop a new motor assessment of space exploration in a 2D environment with upper limbs for children with spinal muscular atrophy 1 and 2 from 3 until 16 years old.
- Trial name
- ExplorASI (NCT03223051)
- Testing
- Motor assessment
- Where
- 2 sites in France
- Volunteers
- 30 people
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Cerebral Palsy, Spastic
The Effect of Task-oriented EMG-triggered ES on Upper Limb Motor Function in Hemiplegic Cerebral Palsy
The purpose of our study; to investigate the effects of EMG-induced ES treatment on hand functions, muscle strength, and quality of life in patients with hemiplegic CP.
- Trial name
- NCT04394819
- Testing
- electromyography-triggered electrical stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- nihal tezel
Cerebral Palsy
Cognitive Sensory Motor Training Therapy for Children With Cerebral Palsy
The current study will be randomized controlled trial, data will be collected from Central Park Teaching Hospital. The study will include 32 participants equally divided into two groups and randomly allocated.
- Trial name
- NCT07248566
- Testing
- Cognitive Sensory Motor Training Therapy, conventional occupational therapy
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Pes Plano Valgus, Flatfeet
Calcaneal Neck Lengthening Osteotomy in Children With Artificial Bone Graft
In a group of children with severe and painful flatfeet lengthening procedures of calcaneus can be indicated. In this study the investigators use an artificial bone graft technique to avoid removing bone graft from the iliac…
- Trial name
- NCT01618812
- Testing
- Lateral lengthening osteotomy of calcaneus
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- University of Aarhus
LGMDR9
ATA-100 (Formerly GNT0006) Gene Therapy Trial in Patients With LGMDR9
Phase 1 dose escalation study to assess tolerability and safety of ATA-100 with 5-year follow-up
- Trial name
- NCT05224505
- Testing
- ATA-100 (AAV9 encoding FKRP gene)
- Where
- 3 sites in Denmark, France and 1 more
- Volunteers
- 6 people
- Sponsor
- Atamyo Therapeutics
Hemiplegia
Home Based Adaptive Arm Training for Children
Twenty pediatric patients aged 5-17 years with Acquired Brain Injuries (ABI) will be randomized to receive either a bimanual-to-unimanual device home training program (10 subjects) or a conventional non-device home training…
- Trial name
- NCT02751502
- Testing
- m2 Bimanual Arm Trainer (BAT)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- NYU Langone Health
Chronic Limb-Threatening Ischemia Nos of Native Arteries of Extremities
GLASS Classification and CLTI
Critical limb threatening ischemia "CLTI 'is not a separate local disease but also it is a part of generalized vascular disorder.
- Trial name
- NCT05209672
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Assiut University
Amputation
Effectiveness of Frontal Plane Adaptability in a Novel Foot Prosthesis
People with lower extremity amputation (LEA) have persistent problems with balance, falls, residual limb pain, functional mobility, cognitive attention during gait, and satisfaction with participation in daily activities, despite…
- Trial name
- NCT06214026
- Testing
- META-Arc foot locked, META-Arc foot unlocked
- Where
- 3 sites in United States
- Volunteers
- 96 people
- Sponsor
- University of Washington
Limb-girdle Muscular Dystrophy
A Trial to Learn More About an Experimental Gene Therapy Called Bidridistrogene Xeboparvovec (SRP-9003) as a Possible Treatment for Limb Girdle Muscular Dystrophy 2E/R4
This is a multicenter, global study of the effects of a single systemic dose of SRP-9003 on beta-sarcoglycan (β-SG) gene expression in participants with limb-girdle muscular dystrophy, type 2E/R4 (LGMD2E/R4).
- Trial name
- EMERGENE (NCT06246513)
- Testing
- SRP-9003, Glucocorticoid
- Where
- 10 sites in United States, Belgium and 4 more
- Volunteers
- 17 people
- Sponsor
- Sarepta Therapeutics, Inc.
Amputation
Effectiveness of Supervised Training Program on Mobility and Balance Confidence in Individual With Lower Limb Amputation
It was quasi experimental study where the researchers assess the effectiveness of supervised training program on mobility and balance confidence in individual with lower limb amputation.
- Trial name
- NCT05180682
- Testing
- Gait Training
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- NCS University System
Cerebral Palsy
Effects of UP-CAT With and Without Visual Feedback in Children With CP
Cerebral palsy (CP) is the most common neurological disorder of movement and/or posture and of motor function, which are due to a non-progressive interference or abnormality of the developing brain.
- Trial name
- NCT06198179
- Testing
- upper limb children action-observation training (UPCAT), upper limb children action-observation training (UP-CAT) with visual feedback
- Where
- Pakistan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Cerebral Palsy, Spastic
Individualized Virtual Reality in the Upper Extremity Rehabilitation of Hemiparetic Cerebral Palsy
This study aimed to investigate the effect of individualized virtual reality therapy on upper extremity functions of children with hemiparetic cerebral palsy.
- Trial name
- NCT04630678
- Testing
- Virtual Reality Therapy, Conventional Physiotherapy, Activity Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hacettepe University
Paraspinal Muscle Relaxation in Spine Surgery
Paraspinal Muscle Relaxation in Spine Surgery
During anesthesia, neuromuscular blocking agents (NMBA) are routinely used for relaxation of muscles necessary for the conduction of the surgical procedure.
- Trial name
- TOF (NCT03318718)
- Testing
- Anesthesia with non-depolarizing NMBA Rocuronium, TOF measurement, MEP measurement
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- Balgrist University Hospital
Chronic Obstructive Pulmonary Disease
Effect of Extremity Exercise in COPD
Objective: is to find out the effect of unsupported upper extremity exercise versus lower extremity exercise on dyspnea and lung function Methodology: Sample and design: 60 patients with Randomized study design will be included…
- Trial name
- NCT04076085
- Testing
- exercise
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- King Khalid University
Spastic Cerebral Palsy
Circuit Training in Children With Cerebral Palsy
The aim of our study is to reveal the results of circuit training to be applied to the children with Cerebral Palsy (CP) for improving their muscular strength and trunk control and also to determine their effects in terms of…
- Trial name
- NCT03529682
- Testing
- exercise, control group
- Where
- Cyprus
- Volunteers
- 62 people
- Sponsor
- Eastern Mediterranean University
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