Clinical trials: Extremity
Cervical Dystonia, Blepharospasm
Efficacy and Safety of 10-Week or Shorter vs 12-Week or Longer Injection Intervals of Botulinum Toxin
Our hypothesis is that botulinum toxin injections (with onabotulinum toxin, incobotulinum toxin, and abobotulinum toxin) given at 10-week or shorter intervals for the indication of treatment of muscle spasms associated with…
- Conditions
- Cervical Dystonia, Blepharospasm, Limb Dystonia, Hemifacial Spasm
- Trial name
- NCT05103202
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- University of Texas Southwestern Medical Center
Genu Varum, Genu Valgus
IMU-based Assessment of Motor Control in a Population of Young Subjects With Paramorphisms and Dysmorphisms
While various complex pathologies of the developmental age, such as Infantile Cerebral Palsy or Neuromuscular Diseases, are notoriously considered causes of alteration of locomotor development, it is scarcely known whether…
- Conditions
- Genu Varum, Genu Valgus, Flat Feet, Cavus Foot
- Trial name
- MOTOR-CHILD (NCT05763901)
- Testing
- Clinical tests and motor control evaluation using Inertial Measurement Units
- Where
- Italy
- Volunteers
- 151 people
- Sponsor
- Istituto Ortopedico Rizzoli
Cancer of the Bone, Limb Salvage
Tranexamic Acid Use to Reduce Blood Transfusion in Pediatric Cancer Patients Undergoing Limb Salvage Procedure
This is a randomized double-blind control trial evaluating the use Tranexamic acid (TXA) to decrease blood loss and transfusion requirements in pediatric and young adult cancer patients undergoing a limb salvage procedure that…
- Trial name
- NCT04410042
- Testing
- Tranexamic Acid, 0.9% sodium chloride
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- St. Jude Children's Research Hospital
Cerebral Palsy
Effects of an HABIT-ILE-Based Intervention in Children With Cerebral Palsy
This interventional study will evaluate the effects of an intensive HABIT-ILE-based camp on cardiorespiratory measures and body composition in children with cerebral palsy.
- Trial name
- UEM-HABITILE (NCT07506837)
- Testing
- HABIT-ILE
- Volunteers
- 30 people
- Sponsor
- Universidad Europea de Madrid
Cerebral Palsy, Upper Extremity Dysfunction
The Effect of Upper Extremity Strengthening on Functionality, Muscle Strength and Trunk in Children With Cerebral Palsy
Cerebral Palsy (CP) is an activity limitation, movement and posture deficiencies in early stage of life. In 80% of these children, upper extremity (UE) dysfunctions are observed, which leads to loss of quality of life, resulting…
- Conditions
- Cerebral Palsy, Upper Extremity Dysfunction, Upper Extremity Functions, Muscle Strength
- Trial name
- NCT05115695
- Testing
- traditional physiotherapy approach, muscle strengthening exercise/Proprioceptive Neuromuscular Facilitation (PNF)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Cerebral Palsy, Motor Deficits
Constraint-Based Therapy to Improve Motor Function in Children With Cerebral Palsy
Pediatric Constraint-Induced (CI) Movement therapy is a rehabilitation program designed to improve motor function in children with partial paralysis.
- Trial name
- NCT00061139
- Testing
- Pediatric Constraint-Induced Movement therapy, Conventional pediatric motor rehabilitation therapy
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Neutral Temperature, Bloody Stool
Temperature of Extremities and Necrotizing Enterocolitis
Bloody stool and necrotizing enterocolitis(NEC) is two main focus in non-neonatal intensive care unit ward and usually lead to longed duration of hospitalization.
- Conditions
- Neutral Temperature, Bloody Stool, Necrotizing Enterocolitis
- Trial name
- NCT04801537
- Testing
- normal body temperature and warm extremities, normal body temperature and cold extremities
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Lower Limb Length Discrepancy (LLD) in Children
Analysis of the Biomechanical Impact of Lower Limb Length Inequality in PEDiatrics
Lower limb length discrepancy (LLD) is a frequent condition in pediatric orthopedics. Even moderate discrepancies can induce pelvic obliquity and compensatory scoliosis, modifying the distribution of joint loads at the hips and…
- Trial name
- ABILMI-PED (NCT07254351)
- Testing
- EOS Imaging System, Force Platform (Bertec®, integrated into EOS cabin)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Cerebral Palsy
Whole Body Vibration Effect on Trunk Control, Functional Performance and Selective Control
Permanent neurological disorders such as cerebral palsy lead to problems with motor, sensory, and cognitive functions, which in turn limit one's ability to do certain activities.
- Trial name
- NCT06461845
- Testing
- Whole Body Vibration group, conventional therapy
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Lower Limb Ischemia
Acute Limb Ischaemia (ALI) Management With 'Indigo' Mechanical Aspiration System
International Multi-Centre registry recording comprehensive data on the use of 'Indigo' Mechanical thrombectomy system by Penumbra Inc for the removal of acute clot causing acute or critical limb ischaemia.
- Trial name
- NCT03295539
- Testing
- 'Indigo' Mechanical thrombectomy system
- Where
- United Kingdom
- Volunteers
- 400 people
- Sponsor
- Lancashire Care NHS Foundation Trust
Pes Plano Valgus, Flatfeet
Calcaneal Neck Lengthening Osteotomy in Children With Artificial Bone Graft
In a group of children with severe and painful flatfeet lengthening procedures of calcaneus can be indicated. In this study the investigators use an artificial bone graft technique to avoid removing bone graft from the iliac…
- Trial name
- NCT01618812
- Testing
- Lateral lengthening osteotomy of calcaneus
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- University of Aarhus
Lower Limb Pronation
Exercise Program for Lower Limb Pronation
Introduction: The prevalence of biomechanical alterations in the the lower limbs in school-age children is increasing. The aim of this study is to assess the effectiveness of a therapeutic exercise program in child athletes with…
- Trial name
- NCT03312101
- Testing
- exercise program
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Seville
Cognitive Games, Sports Performance
Development of a Performance Model for Amputee Football Players
This study aims to investigate the effects of a cognitive game-based exercise program on cognitive and physical performance in amputee football players.
- Conditions
- Cognitive Games, Sports Performance, Lower Limb Amputation
- Trial name
- NCT07840781
- Testing
- Gince Intelligence Game-Based Exercise Program, Routine Training Group
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Tarsus University
Hemiplegia, Cerebral Palsy
The Use of Armeo Spring in Upper Extremity Rehabilitation
The purpose of this study is to evaluate the use of the Armeo®Spring Pediatric as therapy for children with hand and arm weakness.
- Conditions
- Hemiplegia, Cerebral Palsy, Upper Extremity Weakness
- Trial name
- NCT02636205
- Testing
- Armeo therapy
- Volunteers
- 15 people
- Sponsor
- St Mary's Hospital for Children
Lower Limb Spasticity
Effectiveness and Safety of Dysport® (abobotulinumtoxinA) in Paediatric Lower Limb Spasticity
The purpose of this study is to assess the longitudinal attainment of subject centred and functional related goals (cumulated Goal Attainment Scale Total (GAS T) score) after abobotulinumtoxinA injection (including following…
- Trial name
- NCT03017729
- Testing
- Botulinum toxin type A
- Where
- 27 sites in United States
- Volunteers
- 242 people
- Sponsor
- Ipsen
Unilateral Cerebral Palsy
Impact of Somatosensory Intensive Intervention on Motor Performance in Children With Unilateral Cerebral Palsy
This study aims to investigate the effectiveness of an intensive somatosensory intervention in the upper limb of children with hemiparesis regarding structure, function, activity and participation Hypothesis: Intensive…
- Trial name
- NCT04235088
- Testing
- Somatosensory intensive intervention
- Where
- Spain
- Volunteers
- 16 people
- Sponsor
- Universidad San Jorge
Hemiparetic Cerebral Palsy
Using Neurotechology to Help Children With Physical Disability Due to Cerebral Palsy
Hemiparetic cerebral palsy is a condition in which one side of a child's body becomes weak due to brain injury occurring around birth, often caused by stroke.
- Trial name
- NCT07269353
- Testing
- Brain Computer Interface - Functional Electrical Stimulations
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- University of Alberta
Conscious Sedation, Distal Radius Fracture
IN Dexmedetomidine for Procedural Sedation in Pediatric Closed Reductions for Distal Forearm Fractures
The primary objective of this study is to evaluate the sedative, and analgesic effects of intranasal (IN) Dexmedetomidine (DEX) in children presenting to a Pediatric Emergency Department (PED) who undergo conscious sedation for…
- Trial name
- NCT03466242
- Testing
- Dexmedetomidine, Ketamine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Phoenix Children's Hospital
Hemiplegic Cerebral Palsy
Action Observation Versus Mirror Therapy in Children With Spastic Hemiplegic Cerebral Palsy
The goal of this clinical trial is to compare the effects of Action Observation therapy and Mirror therapy on hand grip strength and upper extremity function in children with hemiplegic cerebral palsy.
- Trial name
- NCT07739069
- Testing
- Mirror Therapy, Action Observation Therapy
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Cairo University
Charcot-Marie-Tooth Disease, Charcot-Marie-Tooth
Natural History Study for Charcot Marie Tooth Disease
The goal of this Natural History Study for Charcot-Marie-Tooth is to acquire, record, and analyze patient-reported data and associated genetic reports, Electronic Health Records (EHRs) and clinical notes to identify the burden…
- Conditions
- Charcot-Marie-Tooth Disease, Charcot-Marie-Tooth, Charcot-Marie-Tooth Disease, Type IA, Charcot-Marie-Tooth Disease Type 2A
- Trial name
- NCT05902351
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Hereditary Neuropathy Foundation
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