Clinical trials: Facial Pain
Temporomandibular Joint Disorders, Facial Pain
Efficacy of Combining Low-Level Laser Therapy With a Self-Management Program on Myalgia in Temporomandibular Disorders
The purpose of this study is to evaluate the efficacy of combining low-level laser therapy and the self-management program for patients with temporomandibular joint disorders using a randomized controlled design.
- Trial name
- LASER-SM (NCT06419738)
- Testing
- Self-Management Program, Low level laser therapy combined with Self-Management Program, Occlusal Splint combined with Self-Management Program
- Where
- Vietnam
- Volunteers
- 66 people
- Sponsor
- Hanoi Medical University
Healthy Subjects
Evaluate Onset of Action of a Fast Release Aspirin
To compare the safety and efficacy (onset, duration of relief and overall efficacy) of a single dose of a fast release formulation of aspirin 1000 mg compared to acetaminophen 1000 mg and placebo for relief of pain following…
- Trial name
- TAROT compare (NCT01420094)
- Testing
- Acetylsalicyclic acid (Fast release Aspirin, BAY1019036), Acetaminophen (Tylenol extra strength)
- Where
- United States
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Bayer
Post Operative Pain
Pectointercostal Block for Postoperative Pain Management After Sternotomy
This randomized, controlled study is designed to assess the quality of analgesia provided by ultrasound-guided bilateral pectointercostal facial block in children undergoing cardiac surgery via midline sternotomy.
- Trial name
- NCT05552417
- Testing
- Pectointercostal facial plan block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kasr El Aini Hospital
Stellate Ganglion, Facial Palsy
Stellate Ganglion Block in Longstanding Facial Nerve Palsy Patients
The goal of the present study is to verify the efficacy of stellate ganglion block (SGB) in the treatment of facial pain
- Conditions
- Stellate Ganglion, Facial Palsy, Pain Management
- Trial name
- NCT06742255
- Testing
- Stellate Ganglion Block
- Volunteers
- 34 people
- Sponsor
- Assiut University
Dental Pain
Maxi-Analgesic Phase 2 Study to Compare the Analgesic Effects in Different Dosing Groups to Treat Teeth Extraction Pain
The aim of the study is to examine the dose response relationship in the treatment of dental pain (teeth extraction) for the different potential doses of the investigational drug, i.e.
- Trial name
- NCT01104844
- Testing
- Full Dose Strength, Quarter dose strength, Half dose strength
- Where
- United States
- Sponsor
- AFT Pharmaceuticals, Ltd.
Post-operative Pain
Ibuprofen/Acetaminophen Versus Nurofen Plus® and Panadeine® Extra Dental Pain Study
The objective is to assess the efficacy and tolerability of a combination of 400 mg ibuprofen plus 1000 mg acetaminophen, 200 mg ibuprofen plus 500 mg acetaminophen compared with Nurofen Plus® and Panadeine® Extra.
- Trial name
- NCT01229449
- Testing
- Ibuprofen/acetaminophen, Ibuprofen/acetaminophen (higher dose), Nurofen Plus®
- Where
- United States
- Volunteers
- 678 people
- Sponsor
- Reckitt Benckiser LLC
Pulpitis, Post Operative Pain
Post-Operative Pain After Vital Pulpotomy in Molars With Symptomatic Pulpitis
The goal of this clinical trial is to investigate post-operative pain (PEP) in teeth with symptomatic pulpitis following Vital Pulpotomy Treatments (VPT) with Calcium Silicate Cement (CSC).
- Conditions
- Pulpitis, Post Operative Pain, Toothache
- Trial name
- POPAVPT (NCT06216951)
- Testing
- Vital Pulpotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people
- Sponsor
- Uşak University
Dental Pain, Postoperative Pain
Comparative Efficacy of 20% Benzocaine Versus TAC Alternate Gel
The project is a study comparing the effectiveness of two topical anesthetics for control of pain associated with dental needle insertion in the palatal mucosa.
- Trial name
- NCT00846690
- Testing
- benzocaine, TAC alternate gel
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Pain
Validation of Faces Thermometer Scale (FTS)
The aim of this study is to evaluate validity and reliability of a novel digital pain measure tool, the Faces Thermometer Scale (FTS). Pain is commonly reported by children and adolescents undergoing dental treatment.
- Trial name
- NCT05322018
- Testing
- Faces Thermometer Scale (FTS)
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Malmö University
Myofacial Pain Syndrome, Botulinum Toxin
Botulinum Toxin A in Patients With Myofascial Pain Syndrome With and Without Zinc Supplementation
Research question: Dose the use of oral zinc supplement improve the effects of botulinum toxins injection in patients with myofascial pain dysfunction syndrome? Statement of the problem: MPDS Patients treated with botulinum toxin…
- Trial name
- NCT05605886
- Testing
- Solvazinc 50mg
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Pain, Dental Anxiety
Compare the Intensity of Pain Felt by Children During the Local Anesthesia Procedure to That Perceived by the Accompanying Parent.
The goal of this observational study is to compare the intensity of pain experienced by children (aged 6 to 15) during local anaesthesia with that perceived by the parent accompanying them.
- Trial name
- ADDenT (NCT07718477)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Pulp Disease, Dental, Pulpitis
Predicting Vital Pulp Treatment Outcomes in Symptomatic Pulpits Using Metabolic Biomarker
This prospective controlled clinical trial investigates whether metabolic biomarkers measured in pulpal blood at the time of carious pulp exposure can predict the 12-month outcomes of vital pulp treatment in symptomatic permanent…
- Conditions
- Pulp Disease, Dental, Pulpitis, Reversible Pulpitis, Irreversible Pulpitis (Toothache)
- Trial name
- NCT07452614
- Testing
- vital pulp treatment
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Abeer Ghalib Abdul-khaliq
Pain
Study Evaluating the Efficacy of an Ibuprofen Effervescent Tablet in the Treatment of Post-Surgical Dental Pain
Evaluation of the efficacy and safety of a single dose of an ibuprofen effervescent tablet in the treatment of pain following third molar extraction in comparison to single doses of placebo, standard ibuprofen tablets, and…
- Trial name
- NCT00631111
- Testing
- effervescent ibuprofen tablets, effervescent Aspirin plus Vitamin C tablets, ibuprofen tablets
- Where
- United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Dental Pain, Dental Anxiety and Child Behavior Are Assess in Response to Dental Injection
Effect of Computer-controlled vs. Conventional Injection on Pain and Anxiety in Children
This randomized controlled trial aims to compare the effectiveness of Computer-Controlled automatic injection device versus conventional injection techniques in pediatric dental patients.
- Trial name
- NCT07193342
- Testing
- computer controlled automatic injection (Star pen® system), conventional anesthetic syringe
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Future University in Egypt
Impacted Mandibular Third Molar Extraction, Post Operative Complications
A Comparison of Recovery After Impacted Wisdom Tooth Removal
Justification of the Study There is a high prevalence of impacted third molars, often accompanied by a range of postoperative complications.
- Trial name
- CESE-3M (NCT07304882)
- Testing
- serratiopeptidase, Escin, Conventional drugs
- Where
- Yemen
- Volunteers
- 24 people
- Sponsor
- University of Science and Technology, Yemen
Pain, Local Infiltration
Pain Perception With a Comfort-ın Jet Injection and Conventional Dental Injection
The investigators aimed to compare the effectiveness of the Comfort-in system, which is a jet injection type, and infiltrative anesthesia with a traditional injector, and to measure the effect of children's anxiety on the…
- Conditions
- Pain, Local Infiltration, Anesthesia, Fear
- Trial name
- NCT04682080
- Testing
- Needle-free injection
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Dental Anaesthesia, Dental Pain
Photobiomodulation and Tooth Analgesia
The purpose of this study is to test photobiomodulation (PBM) with a non-invasive light device for reducing discomfort during dental treatments in children.
- Conditions
- Dental Anaesthesia, Dental Pain, Dental Analgesia
- Trial name
- NCT06691269
- Testing
- Photobiomodulation, Topical Benzocaine, Local Anesthesia
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Dental Pain
Study of Acetaminophen (ACE) in Post-operative Dental Pain
This is a dental pain study evaluating the efficacy and safety of a single dose of test acetaminophen (ACE) (1000 mg) compared to commercial acetaminophen (1000 mg), ibuprofen (IBU) (400 mg), and placebo over a 6 hour period.
- Trial name
- NCT02320708
- Testing
- Acetaminophen (ACE) (1000 mg), Commercial ACE (1000 mg), Commercial Ibuprofen (IBU) (400 mg)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Johnson & Johnson Healthcare Products Division of McNEIL-PPC, Inc.
Pain
A Study of an Acetaminophen/Naproxen Sodium Fixed Combination, Acetaminophen and Naproxen Sodium in Postoperative Dental Pain
The purpose of this study is to evaluate how well a fixed combination of acetaminophen/naproxen sodium relieves postoperative dental pain compared with acetaminophen, naproxen sodium and placebo.
- Trial name
- NCT05761574
- Testing
- Acetaminophen/Naproxen Sodium Fixed Combination, Naproxen Sodium, Acetaminophen
- Where
- United States
- Volunteers
- 447 people
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Pain, Postoperative, Pain, Chronic
fMRI and IVCM Cornea Microscopy of CXL in Keratoconus
Evaluation of neuroplasticity of pain pathways and corneal afferent nerve regeneration following corneal crosslinking (CXL) in keratoconus patients using fMRI and corneal In Vivo Confocal Microscopy (IVCM).
- Conditions
- Pain, Postoperative, Pain, Chronic, Pain, Acute, Surgical Injury
- Trial name
- NCT04439552
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital