Clinical trials: Fistula;Rectal
Post-COVID-19 Condition, Ulcerative Colitis
Emerging Indications for Hyperbaric Oxygen Treatment
This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially benefit from HBOT) using the Multicenter Registry for Hyperbaric…
- Conditions
- Post-COVID-19 Condition, Ulcerative Colitis, Crohn Disease, Calciphylaxis
- Trial name
- NCT07240649
- Testing
- Hyperbaric oxygen treatment (HBOT), 100% Oxygen
- Volunteers
- 100 people
- Sponsor
- Jay C. Buckey Jr.
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Colonic Fistula
Endoscopic Management Of Low Output Recurrent Colonic Fistula Or Leak After Anterior Resection For Rectal Cancer
This prospective randomized controlled clinical trial included all patients who developed the manifestations of low output recurrent colonic fistula or leak after colonic anterior resection for rectal cancer at Zagazig University…
- Trial name
- NCT05659446
- Testing
- endoscopy management of low output colonic fistula or leak after anterior resection for rectal cancer
- Where
- Egypt
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Fistula in Ano
Fistulotomy With Marsupialization Versus Fistulectomy With Wound Sutures in Simple Anal Fistula
comparison between fistulectomy wound closure and fistulotomw wound marsupialization in treatment of simple anal fistula
- Trial name
- NCT04215718
- Testing
- fistulotomy and marsupialization, fistulectomy and wound closure
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Zagazig University
Anal Fistula
Randomized Trial on the Effect of Topical Phenytoin on Healing After Fistulotomy
Patients with anal fistula who will undergo anal fistulotomy will be randomized into one of two groups; the first group will receive topical phenytoin therapy postoperatively and the second group will not receive such topical…
- Trial name
- NCT03096522
- Testing
- Phenytoin 2% spray, Anal fistulotomy
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- Mansoura University
Anal Fistula
3D Endoanal Ultrasound and Anal Fistula
The study aims to evaluate the use of 3D endoanal ultrasound in preoperative management of anal fistula disease.
- Trial name
- UFU (NCT03937752)
- Testing
- 3D endodanal ultrasound
- Where
- Sweden
- Volunteers
- 95 people
- Sponsor
- Region Skane
Anal Fistulas, Anal Fistula
Identifying Landmark Factors of Anal Fistulas
The goal of this observational study is to understand the effects of anatomical factors, etiology, and complexity of anal fistula on the prognosis of patients undergoing anal fistula surgery within one year post-operation.The…
- Trial name
- NCT06421129
- Testing
- anal fistula surgery
- Where
- China
- Volunteers
- 326 people
- Sponsor
- Guanlin Liu
Anal Fistula
Long-term Follow-up of Anal Fistula Plug
Aim of the study is to evaluate long-term success rate of Biodesign® anal fistula plug for treatment of complex trans-sphincteric anal fistulas.
- Trial name
- NCT03961984
- Testing
- Biodesign® anal fistula plug
- Where
- Sweden
- Volunteers
- 95 people
- Sponsor
- Region Skane
Fistula in Ano, Crohn Disease
Pediatric MSC-AFP Sub-study for Crohn's Fistula
The purpose of this study is to determine the safety of using an autologous mesenchymal stromal cell (MSC) coated fistula plug in people with fistulizing Crohn's disease.
- Trial name
- NCT03449069
- Testing
- MSC-AFP
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Mayo Clinic
Fistula Vagina, Fistula;Rectal
Rectovaginal Fistula Repair
This study is a prospective evaluation of quality-of-life after rectovaginal fistula repair at our institution
- Trial name
- NCT05006586
- Where
- Sweden
- Volunteers
- 55 people
- Sponsor
- Uppsala University
Anal Fistula
Surgisis Anal Fistula Plug Study: An Experience in Saudi Arabia
The Surgisis Anal Fistula Plug study is a clinical trial conducted in Saudi Arabia to study the safety and effectiveness of the Surgisis AFP Plug in the treatment of chronic anal fistulas.
- Trial name
- SurgiSIS AFP (NCT00703131)
- Testing
- Anal Fistula Plug (SurgiSIS AFP)
- Where
- Saudi Arabia
- Volunteers
- 35 people
- Sponsor
- Cook Group Incorporated
Fistula in Ano
Role of Udumbara Sutra in the Management of Fistula in Ano a Rare Case Study
The anal fistula is a notorious disease due to its recurrence rate. Bhagandara is varyingly defined as a tear, ulcer or boil at Bhaga (Perianal region) within 2 finger circumference of it, causing painful abscess when opened is…
- Trial name
- Bhagandara (NCT01954225)
- Testing
- Udumbara Sutra
- Where
- India
- Volunteers
- 1 people
- Sponsor
- Government Ayurved College and Hospital
Anal Fistula
Re-routing in Treatment High Anal Fistula
The aim of this study is to evaluate the role of rereouting in treatment of high anal fistula and evaluate the success rate, the recurrence and incontinence and see if rerouting of the track is a good choice in treatment of high…
- Trial name
- NCT05476146
- Testing
- Rerouting of the track in high anal fitula
- Volunteers
- 50 people
- Sponsor
- Assiut University
Anal Fistula
INVESTIGATION OF THE EFFICACY OF FISTULA OBLITERATION BY STEAM ABLATION IN PERİANAL FISTULAS
Perianal fistula(PF) is one of the most frequent disease in anorectal disease.The incidence of PF is 8,6 -10 / 100 000 . The first surgical treatment is defined by Hippocrates in PF .This surgical treatment which found by…
- Trial name
- STEAM (NCT04811105)
- Testing
- steam ablation
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Perianal Fistula, Perianal Crohn Disease
Regenerative Therapy With Autologous Stromal Vascular Fraction Derived Mesenchymal Stem Cells and Platelet-rich Plasma to Treat Complex Perianal Diseases
Consecutive patients with complex anal fistula were prospectively followed for 12 months. Routine MRI was performed before and at 4 and 12 months after surgery. Continence was assessed likewise using a validated questionnaire.
- Conditions
- Perianal Fistula, Perianal Crohn Disease, Anal Fissure, Rectovaginal Fistula
- Trial name
- NCT05709717
- Testing
- Regenerative therapy with SVF-PRP to supplement perianal surgery
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Kantonsspital Winterthur KSW
Anal Fistula
LIFT Technique Versus Seton in Management of Anal Fistula
Abscesses and anal fistulas represent about 70% of perianal suppuration, with an estimated incidence of 1/10,000 inhabitants per year and representing 5% of queries in coloproctology.
- Trial name
- NCT03311035
- Testing
- Seton, LIFT technique
- Volunteers
- 60 people
- Sponsor
- Assiut University
Fistula in Ano
Fistula-in-ano in Infants and Children
In this prospective, randomized trail, duration of non-cutting seton placement in patients with fistula-in-ano is evaluated.
- Trial name
- NCT05666609
- Testing
- placement of non-cutting seton (silicone)
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Friedrich-Alexander-Universität Erlangen-Nürnberg
Anal Fistula Surgery, Anal Fistula
The Modified Clipped-LIFT Procedure for High Transsphincteric or Suprasphincteric Fistula
A retrospective analysis was performed on 96 patients who underwent modified LIFT procedures to treat transsphincteric or suprasphincteric fistulas.
- Trial name
- NCT07102134
- Testing
- Suturing-LIFT procedure, Clipped-LIFT procedure
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Rectal Cancer
Fistula-associated Anal Adenocarcinoma
The fistula-associated anal adenocarcinoma is rare in patients suffering from anal fistulas. There is only little data available for this patient collective making characterization and management of this disease difficult.
- Trial name
- NCT05381324
- Volunteers
- 1,004 people
- Sponsor
- Medical University of Vienna
Hemorrhoids, Anal Fissure and Fistula
Pudendal Nerve Block With Bupivacaine Alone and Bupivacaine With Methylene Blue for Postoperative Analgesia
Study Description: The goal of this clinical trial is to compare the duration of postoperative pain relief achieved with two different approaches to pudendal nerve block in patients undergoing elective perianal surgery.
- Conditions
- Hemorrhoids, Anal Fissure and Fistula, Perianal Abscess, Perianal Fistula
- Trial name
- NCT05990569
- Testing
- Ultrasound guided Pudendal nerve block
- Where
- Nepal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nepal Mediciti Hospital