Clinical trials: Frozen Embryo Transfer
Infertility, Female, IVF
RCT to Assess the Impact of Microbiome Status in Infertile IVF Patients at Their First IVF/ICSI Cycle
Although the endometrium has been traditionally considered free of bacteria, recent studies have documented the presence of an endometrial microbiome.
- Trial name
- NCT04686357
- Testing
- EMMA/ALICE
- Volunteers
- 1,018 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Infertility
Frozen Embryo Transfer (FET) in Natural Cycles or in Natural Cycles Controlled by Human Chorionic Gonadotropin (hCG) Administration
The rational of the study is to assess the implantation, pregnancy and live birth rates after the transfer of frozen- thawed embryos in natural cycles with spontaneous Luteinizing Hormone (LH)/Progesterone rise or in natural…
- Trial name
- FRET (NCT00809107)
- Testing
- HCG
- Where
- Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Endometrial Receptivity
Comparison of Blood Flow in the Arteriae Uterinae in Ovarian Stimulation Cycles
This study will measure the blood flow in the aa. uterinae in women, undergoing firstly ovarian stimulation for In-Vitro Fertilization (IVF) / Intracytoplasmic sperm injection (ICSI), in Hormonal Replacement cycles (HRT) and…
- Trial name
- NCT03887728
- Where
- United Arab Emirates
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Infertility
Effect of Endometrial Injury Before Frozen Embryo Transfer on Pregnancy Rate
Research Question: In women undergoing frozen embryo transfer, does routine endometrial injury before frozen embryo transfer increase clinical pregnancy rate? Research Hypothesis: (Null Hypothesis) In women undergoing frozen…
- Trial name
- NCT03220503
- Testing
- endometrial injury
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams Maternity Hospital
IVF
Effect of HCG on Endometrial Preparation in Frozen Embryo Transfer
Intramuscular injection of HCG to prepare endometrium for frozen embryo transfer
- Trial name
- NCT06577181
- Testing
- hCG + estradiol, Observation arm
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
IVF, Frozen Embryo Transfer
Lipiodol Prior to FET (LIFE)
Lipiodol® flushing is an effective fertility treatment for women with unexplained infertility. It is speculated that the treatment effect could work through a direct effect of Lipiodol® on the endometrium.
- Conditions
- IVF, Frozen Embryo Transfer, Hysterosalpingography
- Trial name
- LIFE (NCT06563908)
- Testing
- Lipiodol® uterine treatment prior to IVF/ICSI
- Volunteers
- 784 people
- Sponsor
- Mỹ Đức Hospital
Fertility Issues
Correlation of Urinary and Serum Hormone Levels in Natural Cycle Frozen Embryo Transfer Cycles
To evaluate whether the measurement of urinary estrone glucuronide and luteinizing hormone (LH) concentrations with an at-home device is correlated with serum hormone levels within a natural cycle frozen embryo transfer protocol.
- Trial name
- MIRA (NCT06410170)
- Testing
- MIRA Device
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ottawa Fertility Centre
Endometrium, Laser
Intravenous Laser Irradiation Effect on Treatment Resistant Thin Endometrium
We will recruit 30 poor ovarian responders and thin endometrium patients, aged 35-45 year old, and treat with intravascular laser irradiation of blood (ILIB) via an intravenous catheter for irradiation of the blood under a period…
- Trial name
- NCT03081130
- Testing
- Intravenous laser irradiation treatment
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Veterans General Hospital.
Assisted Reproductive Techniques, Pregnancy
Incidence of Pulmonary and Venous Thromboembolism in IVF Pregnancies After Fresh and Frozen Embryo Transfer
In vitro fertilization (IVF) is associated with an increased risk of venous thromboembolism and in particular pulmonary embolism during the first trimester.
- Conditions
- Assisted Reproductive Techniques, Pregnancy, Pulmonary Embolism, Venous Thromboembolism
- Trial name
- NCT03660007
- Testing
- Fresh or frozen embryo transfer IVF
- Volunteers
- 902,891 people
- Sponsor
- Karolinska Institutet
ART, IVF
Health in Childhood Following Assisted Reproductive Technology
The purpose of this trial is to investigate the metabolic and cardiovascular health in children aged 6-8 years born after in-vitro fertilization with frozen embryo transfer
- Conditions
- ART, IVF, Cardiovascular Risk Factor, Hypertension
- Trial name
- HiCART (NCT03719703)
- Where
- Denmark
- Volunteers
- 606 people, healthy volunteers welcome
- Sponsor
- Anja Bisgaard Pinborg
Child Development, Endometrial Preparation
Development of IVF/ICSI Children Born From Different Endometrial Preparation Protocols
The efficacy and safety of endometrial preparation regimens remain controversial. In the most recent meta-analysis, using natural and modified natural cycle protocol to prepare the endometrium in frozen embryo transfer resulted…
- Trial name
- MONARTBABIES (NCT05502770)
- Testing
- Developmental score according to The Ages & Stages Questionnaires®, Third Edition - ASQ®-3, Physical development and General Health, Developmental Red flags
- Where
- Vietnam
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Mỹ Đức Hospital
Progesterone Supplementation
Optimal Length of Progesterone Supplementation Before the Transfer of Cryopreserved (Frozen)-Thawed Day 3 Embryos in an Artificial Cycle With Exogenous Estrogen and Progesterone
Cryopreserved-thawed embryos are often replaced in an artificial cycle, in which the endometrium is prepared by exogenous estrogen and progesterone with or without the use of GnRH agonist downregulation.
- Trial name
- PROFETA-3 (NCT01940653)
- Testing
- Progesterone
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Singeleton Conceived Fresh and Frozen Embryo Transfer (ICSI/IVF), Naturally Conceived
NEURODEVELOPMENTAL OUTCOMES OF SINGLETON CONCEIVED FROM FRESH AND FROZEN EMBRYO TRANSFER COMPARED WITH NATURALLY CONCEIVED
This study aimed to: detect difference in neurobehavior, maturity, Apgar score and birth weight of singleton conceived from fresh and frozen embryo transfer and naturally conceived.
- Trial name
- NCT04772872
- Testing
- Assessment by Brazelton neonatal behavior for group A,Band C
- Where
- Egypt
- Volunteers
- 186 people
- Sponsor
- Cairo University
Fertility Disorders
ASA 81 mg vs 162 mg During Frozen Embryo Transfer (FET)
The use of low dose aspirin is recommended for high risk patients to reduce the risk of pre-eclampsia, placental abruption and antepartum hemorrhage.
- Trial name
- NCT06128395
- Testing
- Frozen embryo transfer
- Where
- Canada
- Volunteers
- 1,207 people
- Sponsor
- Clinique Ovo
Pregnancy
Vitrification Versus Spontaneous Conception and Slow- Rate Freezing
Great scientific effort has been made to improve practical as well as economical procedures of modern assisted reproduction. In the last years a shift from the well established method of slow-rate freezing to vitrification of 2PN…
- Trial name
- NCT01088425
- Testing
- Observation
- Where
- Germany
- Volunteers
- 850 people
- Sponsor
- University of Luebeck
Infertility, Female, IVF/ICSI
RCT to Assess the Clinical Benefit of the ERA Test in Infertile Women at Their First IVF/ICSI Cycle
Endometrial receptivity takes place in a self-limited period of time during the endometrial mid-secretory stage. This period, named as window of implantation (WOI), is modulated by molecular changes allowing embryo implantation…
- Trial name
- NCT04687670
- Testing
- ERA
- Where
- 3 sites in China
- Volunteers
- 714 people
- Sponsor
- Peking University Third Hospital
Infertility, IVF
Health of Frozen Transferred Versus Fresh Transferred Children
In order to give strong recommendation on the efficacy and safety of fresh versus frozen embryo transfer, we conduct this study in order to investigate the physical and mental development of children from fresh versus frozen…
- Trial name
- NCT04099784
- Testing
- Developmental score according to The Ages & Stages Questionnaires®, Third Edition - ASQ®-3, Physical development and General Health, Developmental Red flags
- Where
- Vietnam
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Mỹ Đức Hospital
Infertility, Embryo Transfer
Mucus Removal Before Embryo Transfer
Despite these revolutionary changes in the laboratory, little has changed with the process of embryo transfer (ET). A study to prospectively evaluate the role of cervical mucus removal prior to embryo transfer on pregnancy rates…
- Trial name
- MUCRET (NCT03292770)
- Testing
- Flushing Catheter
- Where
- Spain
- Volunteers
- 1,118 people, healthy volunteers welcome
- Sponsor
- Fundacion Dexeus
Preimplantation Genetic Testing (PGT), Frozen Embryo Transfer Cycle
Effects of Trophectoderm (TE) Biopsy on the Health and Development of Children Born After Preimplantation Genetic Testing (PGT) Cycles.
This study aims to investigate the effects of trophectoderm (TE) biopsy on the health and development of children born after preimplantation genetic testing (PGT) cycles.
- Conditions
- Preimplantation Genetic Testing (PGT), Frozen Embryo Transfer Cycle, Assisted Reproduction Technologies, Postnatal Health
- Trial name
- NCT07349966
- Testing
- Questionnaire
- Where
- Italy
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Fertility Disorders
Natural Frozen Embryo Transfer (FET) vs Substituted Frozen Embryo Transfer (FET)
In frozen embryo transfer substituted cycles, patients are treated with progesterone and estrogen in an attempt to mimic the natural cycle and a transfer is planned whenever the endometrium is ready.
- Trial name
- NCT06053827
- Testing
- Frozen embryo transfer
- Where
- Canada
- Volunteers
- 1,207 people
- Sponsor
- Clinique Ovo