Clinical trials: Functional Ability
Juvenile Arthritis, Cardiorespiratory Fitness
Impact of Pilates Exercise in Children With Juvenile Idiopathic Arthritis
Juvenile idiopathic arthritis (JIA) is one of the most common chronic childhood inflammatory diseases that is characterized by permanent joint inflammation attributable to immune system disturbance.
- Conditions
- Juvenile Arthritis, Cardiorespiratory Fitness, Quality of Life
- Trial name
- Arthritis (NCT05231057)
- Testing
- Pilates exercises, Conventional physical therapy program
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Qassim University
Anxiety Disorder, Head Injury
Neuropsychological Evaluation of Psychiatric and Neurological Patients
This study will allow researchers to use various types of tests to evaluate cognitive and sensory functions. These tests, referred to as "batteries" will evaluate attention, executive functions, general intellectual functioning…
- Conditions
- Anxiety Disorder, Head Injury, Mood Disorder, Schizophrenia
- Trial name
- NCT00001192
- Where
- 7 sites in United States, France and 1 more
- Volunteers
- 4,300 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Childhood Cancer
ADLs at the End of Acute Treatment for Childhood Leukemia and Non-Hodgkin Lymphoma
Reduced activity levels and reduced muscular strength could severely impair the activities of daily living (ADLs) in pediatric leukemia and Non-Hodgkin lymphoma patients.
- Trial name
- NCT05235633
- Testing
- Assessment of the accomplishment regarding Activities of Daily Living at the end of acute treatment
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Technical University of Munich
Sickle Cell Disease, Cognitive Ability, General
Improving Parental Psychosocial Functioning and Early Developmental Outcomes in Children With Sickle Cell Disease
There are all significant risk factors for poor early cognitive development and, as such, neurocognitive deficits have been demonstrated in pre-school children with sickle cell disease (SCD).
- Conditions
- Sickle Cell Disease, Cognitive Ability, General, Psychological Stress, Parenting
- Trial name
- NCT02394899
- Testing
- Play therapy, Problem solving skills
- Where
- Jamaica
- Volunteers
- 64 people
- Sponsor
- The University of The West Indies
Spinal Muscular Atrophy
Motor Function and Activity of Daily Life in Spinal Muscular Atrophy
This study will incorporate patients/ caregivers' perspectives to investigate the performance in daily activities of individuals with SMA and how it relates to their motor function abilities.
- Trial name
- NCT05931211
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Cognitive Deficits, Cognitive Ability, General
Childhood Anesthesia and Cognitive Function
The purpose of this study is to determine whether pediatric anesthesia is associated with long-term hippocampal dysfunction
- Trial name
- UCSF-Anes-01 (NCT01359215)
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level
Multi-functional Neuroprosthetic System for Restoration of Motor Function in Spinal Cord Injury
This study is to evaluate the use of a fully implanted device for providing hand function, reach, and trunk function to individuals with cervical spinal cord injury. Funding Sources: FDA OOPD NIH NINDS
- Conditions
- Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level, Spinal Cord Injury Cervical, Spinal Cord Injury at C5-C7 Level With Complete Lesion
- Trial name
- NNP-UE+T (NCT02329652)
- Testing
- Networked Neuroprosthetic System for Grasp and Trunk
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Anne Bryden
Healthy Volunteer, Muscular Atrophy, Spinal
Ability of Muscle Imaging and Motor Function Measure (MFM) to Detect Changes in Disease Progression in Ambulant Spinal Muscular Atrophy Patients Compared to Healthy Volunteers.
This non-drug, single center, 24-week, longitudinal study in ambulant spinal muscular atrophy (SMA) patients and in age- and gender-matched healthy volunteers will assess the detection of disease progression by magnetic resonance…
- Trial name
- NCT02044029
- Where
- Switzerland
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Achondroplasia
Interventional Study of Infigratinib in Children < 3 Years Old With Achondroplasia (ACH)
This is a Phase 2, multicenter, randomized, placebo-controlled study to evaluate the safety and efficacy of infigratinib in participants < 3 years old with ACH.
- Trial name
- NCT07169279
- Testing
- Infigratinib is provided as a single dose of minitablets for oral administration, Infigratinib is provided as sprinkle capsules for daily oral administration
- Where
- 12 sites in United States, Australia and 5 more
- Volunteers
- 77 people
- Sponsor
- QED Therapeutics, a BridgeBio company
Liver Cirrhosis, Alcoholic
Feasibility of Wearable Biosensors for Monitoring Daily Activity, Heart Rate, and Sleep Among Patients With Decompensated Cirrhosis
In this protocol, the investigators will determine compliance, acceptability, and patient satisfaction regarding the use of remote monitors and summarize changes in activity over time among patients with decompensated cirrhosis.
- Trial name
- NCT06057870
- Testing
- Application on Apple watch
- Volunteers
- 20 people
- Sponsor
- Cedars-Sinai Medical Center
COVID-19
Predicting COVID-19 Patients' Clinical Outcomes Using ICU Mobility Scale and MRC Sum Score
The investigators hypothesize that early mobility condition and muscle power may be the predictive factors for Coronavirus disease 2019(COVID-19) patients' activity prognosis and hospitalization days.
- Trial name
- NCT05195736
- Where
- Taiwan
- Volunteers
- 33 people
- Sponsor
- Taichung Veterans General Hospital
Juvenile Idiopathic Arthritis (JIA)
Reliability and Validity of the Glittre Activities of Daily Living Test in Children and Adolescents With Juvenile Idiopathic Arthritis
Juvenile Idiopathic Arthritis (JIA) is children's most common inflammatory rheumatic disease. The International League of Associations for Rheumatology (ILAR) defines it as a chronic arthritis condition that begins before the age…
- Trial name
- NCT06806774
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Hacettepe University
Cerebral Palsy Spastic Diplegia
Investigation of the Effects of Diaphragm Exercises in Children With Cerebral Palsy
The aim of this study is to examine the effects of diaphragmatic myofascial relaxation exercise and diaphragmatic breathing exercises added to the conventional physiotherapy and rehabilitation program in children with diplegic…
- Trial name
- NCT05559346
- Testing
- Diaphragmatic exercises, conventional physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Uskudar University
Secondary Dystonia, Cerebral Palsy, Mixed
The Effect of Dystonia Severity on Participation in Daily Living Activities and Caregivers in Children of Cerebral Palsy With Secondary Dystonia
Dystonia is the most common movement disorder in the pediatric population after spasticity. It can affect normal motor development and cause significant motor retardation.
- Trial name
- NCT06307561
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Acıbadem Atunizade Hospital
Stroke, Knowledge, Attitudes, Practice
Effects of an Educational Intervention on Rehabilitation Clinicians' Practices for Health-related Outcomes After Stroke
The overall aim of this pilot study is to evaluate the feasibility of a study protocol for a future stepped wedge cluster randomized clinical trial (c-RCT) that will investigate the effects of an innovative KT intervention on 1)…
- Conditions
- Stroke, Knowledge, Attitudes, Practice, Physical Disability, Motor Skills Disorders
- Trial name
- NCT03807115
- Testing
- Implementation of stroke mobility guidelines
- Where
- 6 sites in Canada
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- McGill University
Child Development
The Role of Motion in Infants' Ability to Categorize
This study is concerned with psychological and physiological development in infants. Specifically, researchers are interested in when and how babies are able to group similar objects, like animals or vehicles, into the same…
- Trial name
- NCT00362076
- Where
- United States
- Volunteers
- 941 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Hematopoietic Stem Cell Transplantation
Effectiveness Rehabilitation Hematopoietic Transplantation (ovERsHOT)
The objective of the study is to evaluate the benefits and costs of a comprehensive rehabilitation program (physical, psychological, social and educational) for patients receiving hematopoietic stem cell transplantation (HSCT).
- Trial name
- ovERsHOT (NCT03324620)
- Testing
- Specific program functional and respiratory rehabilitation
- Where
- Spain
- Volunteers
- 190 people
- Sponsor
- Hospital Clinic of Barcelona
Neuromuscular Disease, Neuromuscular Disability
The Effects of a Dynamic Arm Support in Daily Life
The goal of this mixed method study is to learn about how a dynamic arm support device (DAS) helps people with everyday activities. The study focuses on people with neuro(-muscular) conditions, age 16 and older.
- Conditions
- Neuromuscular Disease, Neuromuscular Disability, Assistive Technology, Activities of Daily Living
- Trial name
- NCT07121075
- Testing
- Dynamic arm support
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Hasselt University
Hemophilia, Knee Arthropathy
Hemophilic Knee Arthropathy Virtual Reality
This study intended to examine the effect of a physical rehabilitation program incorporating Kinect-based virtual reality on gait characteristics, functional ability, and physical activity level in adolescents with hemophilic…
- Trial name
- hemophilia (NCT05802368)
- Testing
- virtual reality group, exercise group
- Where
- Saudi Arabia
- Volunteers
- 56 people
- Sponsor
- Maged Basha
Sports Physical Therapy
Comparitive Effects of Reciprocal Inhibtion and Static Stretching Among Female Athletes
The aim of the study is to determine the Comparative effects of Reciprocal Inhibition and Static Stretching on Serratus anterior Muscle on Pain, range of Motion, and Functional ability among Female Amateur Athletes
- Trial name
- NCT06696924
- Testing
- Reciprocal inhibition, Static stretching
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Riphah International University