Clinical trials: Funnel Chest
Deformity of Chest Wall
SPAIN Chest Wall Deformity Project (Pectus Repair)
Context: Chest wall deformities in children are relatively common. One such deformity, known as Pectus Excavatum (PE), involves a concavity of the chest and is the most frequent of these abnormalities - present in approximately 1…
- Trial name
- NCT02098681
- Where
- United States
- Volunteers
- 348 people
- Sponsor
- Boston Children's Hospital
Pectus Excavatum
Three-dimensional Optical Surface Imaging as a Diagnostic Tool in Pectus Excavatum
Pectus excavatum (PE) is the most common anterior chest wall deformity. Currently, a chest radiography (CR) or Computed Tomography (CT) scan is acquired to determine and objectify pectus severity using the Haller Index.
- Trial name
- 3D PECTUS (NCT03926078)
- Testing
- 3D optical surface image, Chest radiography, CT scan
- Where
- Netherlands
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Zuyderland Medisch Centrum
Pectus Excavatum
ES Catheter vs Cryoablation After Pectus Surgery
Participants will be randomized to receive ES catheter or cryoablation for pain management after the Nuss procedure. The goal of this study is to compare the following between the two groups: Time to achieve short-term physical…
- Trial name
- NCT06682208
- Testing
- ES catheter, Intercostal nerve cryoablation (INC)
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pectus Excavatum
Lung Ultrasound for the Postoperative Diagnosis of Pneumothorax in Children
This study will be conducted to determine the advantages and limitations of sonography compared with chest radiography, in the detection of post procedure iatrogenic pneumothorax in patients underwent to Pectus Excavatum (PE)…
- Trial name
- ECO_NUSS (NCT03073616)
- Testing
- Lung ultrasound
- Where
- Italy
- Volunteers
- 66 people
- Sponsor
- Nicola Disma, MD
Pectus Excavatum, Funnel Chest
Effectiveness of One-Minute Versus Two-Minute Cryoanalgesia in Nuss Surgery
Intercostal nerve cryoanalgesia has become a popular method for managing postoperative pain after Nuss procedure, showing greater effectiveness compared to epidural anesthesia and patient-controlled analgesia.
- Trial name
- Cryo-One (NCT06935799)
- Testing
- One minute intercostal nerves cryoanalgesia, Two minutes intercostal nerves cryoanalgesia
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Children's Memorial Health Institute, Poland
Postoperative Pain
Prediction of Acute Postoperative Pain and Analgesic Consumption
Pain is an expected part of surgical recovery but effective pain management remains challenging. The high variability in postoperative pain experience and analgesic treatment response between patients is part of the challenge.
- Trial name
- MIRPEX-3 (NCT02230865)
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Kasper Grosen
Pectus Excavatum, Pectus Carinatum
Physiological Assessments During Non Operative Treatment on the Chest Wall Deformities
The physiological assessment in non-operative treatment on chest wall deformities, are still unclear today. These functional benefits outweigh the aesthetic benefits associated with anatomical improvement.
- Trial name
- PECTUS (NCT02528656)
- Testing
- Vacuum Bell, Dynamic Compression System
- Where
- France
- Volunteers
- 52 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Pectus Excavatum, Pectus Carinatum
Chest Wall Deformities Beyond the Chest Wall
Pectus excavatum (PE) and pectus carinatum (PC) are chest wall deformities that may influence respiratory function, physical capacity, posture, and quality of life.
- Trial name
- BEYOND (NCT07844382)
- Where
- Turkey (Türkiye)
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Pain
Preemptive Genotyping and Pain Management
The purpose of this study is to see if testing for genes related to pain and pain management before surgery affects how patients are treated for pain after surgery.
- Trial name
- NCT01813695
- Testing
- Preemptive genotyping in medical record, Genotyping not included in electronic medical record
- Where
- United States
- Volunteers
- 576 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Postoperative Pain
Pain Management for Pectus Excavatum Repair
The objective of this study is to scientifically evaluate two different management strategies for post-operative pain after pectus excavatum repair.
- Trial name
- NCT00413582
- Testing
- Epidural Analgesia, Patient-Controlled IV Analgesia
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Children's Mercy Hospital Kansas City
Pectus Excavatum, Pectus Deformity
Assessing Virtual Reality for Perioperative Anxiolysis in Adolescents Undergoing MIRPE Surgery
In this randomized control trial, investigators would like to assess as primary objective the effectiveness of VR in anxiolysis via using State Trait Anxiety- Inventory test various time during the perioperative period with…
- Trial name
- NCT06446518
- Testing
- Virtual reality exposure
- Where
- Hungary
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Pectus Excavatum, Pain, Postoperative
Pectus ESC Outcomes and Comparative Effectiveness Study
Investigators hypothesize that Erector spinae catheter pain management protocol would allow patients to have earlier and more effective rehabilitation with decreased length of hospital stay.
- Trial name
- PectusESC (NCT05063695)
- Testing
- Multimodal Erector spinae catheter protocol
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pectus Deformity of Chest, Spinal Deformity
The Relationship Between Pectus Deformities and Spinal Pathologies
Pectus deformities are common anterior chest wall pathologies. Pectus excavatum is the most common chest deformity with an incidence of 0.1-0.3%.
- Trial name
- NCT06009601
- Testing
- Pectus Study Form, Adams Test, Scoliosis Graphy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Pectus Excavatum, Pectus Carinatum
Psychological Assessment of Patients With Chest Wall Deformities
The study aims to investigate the most frequent psychological outcomes associated to chest wall deformities and patients' quality of life.
- Trial name
- NCT04362878
- Where
- Italy
- Volunteers
- 209 people
- Sponsor
- University of Florence
Pectus Excavatum
Investigation of the Effectiveness of Telerehabilitation Training in Pectus Excavatum Deformity
The aim of this study is to investigate the effectiveness of telerehabilitation-based exercise training in addition to Vacuum Bell therapy on physical fitness, respiratory functions, posture and psychosocial factors in boys aged…
- Trial name
- NCT06635083
- Testing
- Telerehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Eastern Mediterranean University
Pectus Excavatum
Nuss Procedure: Clinical Options in Pediatric Pain Management?
A retrospective chart review study analyzing the benefits of patient controlled analgesia, thoracic epidural analgesia, and paravertebral nerve block catheters in patients having surgical repair of pectus excavatum using the Nuss…
- Trial name
- NCT02009267
- Testing
- Patient controlled analgesia, Continuous thoracic epidural infusions, Continuous paravertebral blockade
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Ralph Beltran
Pectus Excavatum
The Effect of Patient Position on the External Haller Index Value Among Patients With Pectus Excavatum
Pectus excavatum is the most common anterior chest wall deformity, affecting up to 1:400 of newborns. The current gold standard to quantify the extent of deformity is by calculating the Haller Index based on a Computed Tomography…
- Trial name
- POSITION (NCT04046835)
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Zuyderland Medisch Centrum
Pectus Deformity, Physical Disability
Comparison of Physical and Psychosocial Characteristics of Pectus Excavatum and Carinatum Patients With Healthy Controls
Chest wall deformities are the development of ribs, cartilage and sternum that form the chest wall together with isolated or abnormalities of the musculoskeletal system. Pectus excavatum and carinatum deformities are most common.
- Conditions
- Pectus Deformity, Physical Disability, Psychosocial Impairment
- Trial name
- NCT04172142
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Pectus Excavatum
Prospective Trial: Pain Management After Pectus Excavatum Repair, Epidural Versus PCA
Pectus excavatum, the most common chest wall deformity, occurs in roughly one in 1000 children. Operative repair of the anterior thoracic concavity has transitioned to the minimally invasive approach with substernal bar placement…
- Trial name
- PectusEpiPCA (NCT01863498)
- Testing
- Epidural, PCA
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Children's Mercy Hospital Kansas City