Clinical trials: Growth & Development
Pregnancy, Malaria
L-ArGinine to pRevent advErse prEgnancy Outcomes (AGREE)
There are few safe, effective, and affordable interventions to improve pregnancy outcomes in low resource settings where the highest rates of poor birth outcomes occur.
- Conditions
- Pregnancy, Malaria, Nutrition, Placental Development
- Trial name
- AGREE (NCT05934318)
- Testing
- L-citrulline
- Where
- Kenya
- Volunteers
- 2,960 people, healthy volunteers welcome
- Sponsor
- Liverpool School of Tropical Medicine
Stunted Growth, Stunting
Child Growth and Development in East London
The overarching objective of this research is to detect poor growth and delayed development early in childhood by developing an automated growth-screening algorithm.
- Conditions
- Stunted Growth, Stunting, Growth Disorders, Child Development
- Trial name
- CGDEL (NCT05419336)
- Where
- United Kingdom
- Volunteers
- 558 people
- Sponsor
- Queen Mary University of London
Grandparents, Growth Disorders
The Effect of Interaction-Based Early Education Program Applied to Grandparents on the Grandchildren's Health
In our study, "Does the early childhood intervention applied to grandparents as caregivers affect the child's growth, development (cognitive and socio-emotional development), and nutrition? Does early childhood intervention apply…
- Conditions
- Grandparents, Growth Disorders, Development, Child, Feeding Behavior
- Trial name
- NCT05916144
- Testing
- Interaction-Based Early Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Very Low Birth Weight Baby, Early Nutrition and the Preterm Infant
Optimizing Nutrition and Milk (Opti-NuM) Project
Early nutrition critically influences growth, neurodevelopment and morbidity among infants born of very low birth weight (VLBW), but current one-size-fits-all feeding regimes do not optimally support these vulnerable infants.
- Conditions
- Very Low Birth Weight Baby, Early Nutrition and the Preterm Infant, Nutritional Requirements, Human Milk Fortification
- Trial name
- Opti-NuM (NCT06870981)
- Testing
- Opti-NuM is an observational secondary use of data/samples study, the investigators will analyze information and specimens from the MaxiMoM platform RCTs. No interventions form part of this study.
- Where
- 6 sites in United States, Canada
- Volunteers
- 1,100 people
- Sponsor
- The Hospital for Sick Children
Human Microbiome, Pediatrics
Human Microbiome Research and Development for Overcoming Pediatric Diseases
Prediction and treatment of pediatric diseases and long-term outcomes through microbiome and multi-omics analysis by life cycle: We aim to demonstrate that a wide range of diseases are associated with gut microbiome dysbiosis and…
- Conditions
- Human Microbiome, Pediatrics, Disease, Growth & Development
- Trial name
- NCT06812091
- Where
- South Korea
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Hanyang University
Inactivity, Physical, Aging
Oral 'Breath Test' to Measure Anabolic Sensitivity to a Protein Meal Across the Age and Physical Activity Spectrum
The purpose of this study is to determine how anabolic sensitivity, in response to the ingestion of a liquid protein meal, differs across the lifespan, between biological sexes, and with varying physical activity levels.
- Conditions
- Inactivity, Physical, Aging, Healthy Aging, Growth & Development
- Trial name
- NFRF (NCT06744491)
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Infant Malnutrition, Nutrition Knowledge
Improving the Nutrition Status of Infants in South-Western Uganda
Undernutrition and growth restriction due to poor diet and inadequate nutrient intake continues to be a global challenge, particularly in the developing countries including Uganda.
- Conditions
- Infant Malnutrition, Nutrition Knowledge, Growth, Cognitive Development
- Trial name
- CHNUDEV (NCT02098031)
- Testing
- Improving nutrition knowledge among mothers
- Where
- Uganda
- Volunteers
- 511 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Growth and Development
Long-term Monitoring of Growth and Development of Pediatric Patients Previously Treated With Everolimus
The primary objective of CRAD001M2305 was to report the long-term effects of everolimus treatment on height, weight and sexual development (using Tanner Stages) in children and adolescents with Tuberous Sclerosis Complex…
- Trial name
- EXIST-LT (NCT02338609)
- Testing
- Everolimus
- Where
- 6 sites in United States, Belgium and 1 more
- Volunteers
- 15 people
- Sponsor
- Novartis Pharmaceuticals
Stunting, Development, Child
Methylation, mIcrobiome, NUtritional sTatus, and dEvelopment of Stunted Children
The investigators will conduct a case-control study among under-two children in Lombok Timur, West Nusa Tenggara, Indonesia. The power required to detect changes in epigenetic markers may not be sufficient in the cohort study.
- Conditions
- Stunting, Development, Child, DNA Methylation, Epigenetics
- Trial name
- MINUTES (NCT05779904)
- Where
- Indonesia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- SEAMEO Regional Centre for Food and Nutrition
Disorders of Sex Development, Growth Disorders
Identifying New Genetic Causes to Development Disorders
Disorders of growth, puberty and sex development can have genetic causes. The exome analysis could detect new mutations responsible for these disorders and the frequency of these mutations in these disorders, their association…
- Conditions
- Disorders of Sex Development, Growth Disorders, Puberty Disorders
- Trial name
- FORDEV (NCT03283852)
- Testing
- blood sample
- Where
- France
- Volunteers
- 1,100 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Infant Premature, Growth and Development
NEOVIDEO : Impact of Monitoring Motor Activity by Video Analysis on the Sleep of Very Preterm Infants
Very premature birth and the necessary hospitalization expose to a risk of morbidity and mortality which impacts the neurodevelopmental prognosis. Sleep and behavior monitoring have not been developed in the neonatal units.
- Conditions
- Infant Premature, Growth and Development, Neurologic Disorder, Sleep Fragmentation
- Trial name
- NCT04624347
- Testing
- Access to video and movement curves
- Where
- 2 sites in France
- Volunteers
- 74 people
- Sponsor
- Rennes University Hospital
Growth Disorders, Dietary Exposure
Evaluating the Effects of an Oral Protein Supplement on Children's Growth Patterns
This single-center, randomized controlled pilot study aims to evaluate the efficacy of TruHeight Growth Protein Shake on improving growth patterns in children aged 4-17 years.
- Conditions
- Growth Disorders, Dietary Exposure, Child Development, Bone Development Abnormal
- Trial name
- NCT06329388
- Testing
- TruHeight Growth Protein Shake
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- TruHeight Vitamins
Obesity, Child Development
CrescNet - Growth Monitoring Network
CrescNet is a network of primary care physicians and pediatricians (n=219) and endocrinological treatment centers (n=33), established in Leipzig in 1998, whose aim is to improve the early detection of growth disorders.
- Conditions
- Obesity, Child Development, Growth Disorders
- Trial name
- CrescNet (NCT03072537)
- Where
- Germany
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Development, Vitamin Deficiency
Vitamin B12, Neurodevelopment and Growth in Nepal
Rationale: Globally, vitamin B12 deficiency is one of the most common micronutrient deficiencies. The only relevant source of Vitamin B12 is animal-source foods.
- Conditions
- Development, Vitamin Deficiency, Malnutrition
- Trial name
- BeLive (NCT02272842)
- Testing
- Vitamin B12
- Where
- Nepal
- Volunteers
- 600 people
- Sponsor
- Centre For International Health
Arrest, Bone
Anabolic Steroid and Propranolol in Paediatric Burn
propranolol and anabolic steroids have a role in pediatric burn patients and their combined effects are to be studied here. They decrease the catabolic response to burn trauma and minimize the duration of growth arrest hence…
- Conditions
- Arrest, Bone, Development, Growth
- Trial name
- NCT05805553
- Testing
- Propranolol, Nandrolone Decanoate
- Where
- Pakistan
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- King Edward Medical University
Growth, Infant Development
The Effect of Baby-Led Weaning and Traditional Complementary Feeding Education on Infant Development
The goal of this [type of study: clinical trial] is to compare compare the nutrition, development, obesity risk and anemia risk of the infant with the BLW method and TCF method given to the mothers of infants who have switched to…
- Conditions
- Growth, Infant Development, Complementary Feeding, Nutrition, Healthy
- Trial name
- NCT05771324
- Testing
- Baby-Led Weaning (BLW), Traditional Complementary Feeding (TCF)
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Growth, Vitamin D Supplementation
Next-generation Effects of Vitamin D Supplementation in Pregnancy
Vitamin D deficiency is common among pregnant women, despite daily vitamin D supplements. This study aims to investigate if maternal vitamin D intake of 90 vs 10 µg affects the overall health, growth, and immune system of the…
- Conditions
- Growth, Vitamin D Supplementation, Immune System Diseases, Child Development
- Trial name
- NCT05616117
- Testing
- Intrauterine 90µg D-vitamin, Intrauterine 10µg D-vitamin
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Nutrition Disorder, Child, Nutrition Disorders in Adolescence
Health and Nutrition Survey on Shenzhen Children
1. Master and analyze the nutritional health, growth and development status of primary and secondary school students in Shenzhen, and discover the main nutritional health, growth and development problems and influencing factors.
- Conditions
- Nutrition Disorder, Child, Nutrition Disorders in Adolescence, Nutritional Deficiency, Nutrition, Healthy
- Trial name
- NCT05244785
- Where
- China
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Shenzhen Center for Chronic Disease Control
Growth & Development
An Integrative Approach to Improve Child Outcomes Through Research-based Parent and Teacher Interventions
The purpose of this study is to learn whether a combination of two research-proven programs, a responsive caregiving parenting program and a teacher training program, will have an effect on infants' and toddlers' language…
- Trial name
- NCT03431545
- Testing
- PALS and, BEECH, Control condition
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Neonatal Necrotizing Enterocolitis, Growth and Development
Effect of Autologous Cord Blood Mononuclear Cells for Digestive System in Preterm Neonates
Pre-clinical animal studies provide robust evidence regarding the beneficial effect of stem cells for intestinal disease. This single-center, randomized, controlled, blinded trial assessed the effect of a single intravenous…
- Conditions
- Neonatal Necrotizing Enterocolitis, Growth and Development, Preterm Infants, Nutrition
- Trial name
- ACBMNC (NCT05138276)
- Testing
- Autologous Umbilical Cord Blood Mononuclear Cells Therapy, 0.9% Sodium Chloride
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Guangdong Women and Children Hospital