Clinical trials: Growth & Development
Craniosynostosis, Sagittal, Scaphocephaly
Examination of Neuromotor Development of Cases Diagnosed with Scaphocephaly
It's an observational study. Purpose of the study: To evaluate the neuromotor development of scaphocephaly cases. 21 infants diagnosed with scaphocephaly aged 2-17 months were included.
- Conditions
- Craniosynostosis, Sagittal, Scaphocephaly, Developmental Delay
- Trial name
- NCT06294626
- Testing
- Group 1
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Acıbadem Atunizade Hospital
Infant Development, Preterm Birth
Auditory Environment by Parents of Preterm Infants
Data on parent-infant physical closeness and infants' auditory environment will be collected among preterm infants when they are at gestational age of 32 to 34 weeks.
- Conditions
- Infant Development, Preterm Birth, Language Development
- Trial name
- APPLE (NCT04826978)
- Testing
- Auditory environment
- Volunteers
- 116 people
- Sponsor
- Turku University Hospital
Inappropriate Prescribing
Using a Mobile Application as a Support at the Prescription of Appropriate Medications for Elderly
Objective: To develop and evaluate the effectiveness of a mobile application to support decision making for prescription drugs to elderly patients.
- Trial name
- NCT02918643
- Testing
- Use of an application to for mobile devices like decision-making support for prescription drugs to elderly patients
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Bahia
Developmental Language Disorder and Language Impairment, Deprivation
Evaluating a Targeted Selective Speech, Language, and Communication Intervention at Scale - Protocol for the 'Happy Talk' Cluster Randomised Controlled Trial.
The overall aim of this clinical trial is to evaluate an at scale version of 'Happy Talk' in a large scale effectiveness study (examining inputs, outputs and outcomes) based on a sample of children from socially disadvantaged…
- Trial name
- HappyTalk (NCT06460090)
- Testing
- Happy Talk
- Where
- 4 sites in Ireland
- Volunteers
- 840 people
- Sponsor
- University College Cork
Mental Health Issue, Adolescent Development
Educators and Young People's Mental Health
The aim of the present study is to assess the current state of mental health of educators and young persons at the education centre for health and care professions in St. Gallen (BZGS) by conducting screening instruments.
- Conditions
- Mental Health Issue, Adolescent Development, Mental Health Wellness 1, Mental Health Wellness 2
- Trial name
- NCT05812313
- Where
- Switzerland
- Volunteers
- 2,950 people
- Sponsor
- Manuel Stadtmann
Schizophrenia, Psychotic Disorders
Medication Adherence in Schizophrenia: Development of a CBT-Based Intervention
This is a randomized pilot study of an intervention based on principles of Cognitive Behavioral Therapy (CBT). This intervention is the Health Dialogue Intervention (HDI) and will be compared to a traditional medical model of…
- Trial name
- NCT00980252
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Illinois Chicago
Metabolic Disease, Neurological and Mental Health Conditions
Singapore PREconception Study of Long-Term Maternal and Child Outcomes
We aim to test the following primary hypothesis that nutrition, lifestyle, and maternal emotional health prior to pregnancy and/or during the first trimester alter the expression of metabolic or neurodevelopmental endophenotypes…
- Conditions
- Metabolic Disease, Neurological and Mental Health Conditions, Genetics Predisposition, Skin Condition
- Trial name
- S-PRESTO (NCT03531658)
- Where
- Singapore
- Volunteers
- 1,054 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Autism Spectrum Disorder
Impact of Early Interventions on Neurocognitive Profile of Children With Autism Spectrum Disorder
The Early start Denver model (Rogers, 2010; Dawson, 2010) is a developmental and behavioral model that aim to enhance socio-comunicative abilities and also global development of children with Autism spectrum disorder (ASD).
- Trial name
- IDEAEYE (NCT03254264)
- Testing
- Early Start Denver Model, 'as-usual' intervention
- Where
- France
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Growth Hormone Deficiency (GHD)
Phase 3 Study of LUM-201 in Children With Growth Hormone Deficiency
The OraGrowtH Phase 3 Trial is a multi-national trial. The goals of the trial are to study LUM-201 as a treatment for Pediatric Growth Hormone Deficiency (PGHD) in naive to treatment children and validate the LUM-201 predictive…
- Trial name
- NCT06948214
- Testing
- LUM-201
- Where
- 55 sites in United States, Argentina and 6 more
- Volunteers
- 150 people
- Sponsor
- Lumos Pharma
Language Development
Impact of Exposure to Television and Electronic Devices on Attention and Language in Children
The objective is to examine association between TV exposure ,mobile device use and other electronic devices on attention and language development in children.
- Trial name
- NCT05659238
- Testing
- the effect on language development & attention
- Volunteers
- 200 people
- Sponsor
- Assiut University
Celiac Disease
Risk of Celiac Disease and Age at Gluten Introduction
The purpose of this study is to determine whether age at introduction of gluten-containing cereals (e.g. wheat) plays a role in influencing the risk of celiac disease (CD) development in infants with a first-degree relative…
- Trial name
- CELIPREV (NCT00639444)
- Testing
- gluten-free, normocaloric diet from 6 to 12 months
- Where
- Italy
- Volunteers
- 703 people
- Sponsor
- Università Politecnica delle Marche
Fractures in Children, Apophysitis
Total Genotype Score, Growth, Maturation and Loading Exposure as Risk Factors for Injury in Elite Male Youth Football
A total genotype risk score was generated based on the findings of previous research for non-contact injury, non-contact muscle injury, tendon injury, ligament injury, fracture injury and apophysitis injury.
- Conditions
- Fractures in Children, Apophysitis, Muscle Strain, Ligament Injury
- Trial name
- NCT05220969
- Testing
- Total Genotype Risk Score
- Where
- 2 sites in United Kingdom
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- St Mary's University College
Child Development
LCPUFA Supplementation: A Multi-Modality Imaging Study
The purpose of this study is to take images of the brain in order to see if long-chain polyunsaturated fatty acid (LCPUFA) exposure during infancy influences brain structure and function in middle childhood.
- Trial name
- NCT02076048
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Kathleen Gustafson, Ph.D.
Autism, Autism Disorders and Maternal Stress
Adapting the Sensory Environment to Reduce Stress in Children With Autism During Dental Visits
This study aims to evaluate the impact of a sensory-adapted dental environment (SADE) on the stress levels and behavioral responses of children with autism spectrum disorder (ASD) during dental visits.
- Conditions
- Autism, Autism Disorders and Maternal Stress, Sensory Integration Disorder, Stress Biomarkers
- Trial name
- SMILED (NCT07887243)
- Testing
- Sensory-Adapted Dental Environment
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Jagiellonian University
Healthy Volunteers
Milk Free From A1-Type β-Casein With Human Milk Oligosaccharides on Gut Health, Immunity, Cognitive Development, and Temperament in Toddlers
The aim of the study is to compare the effects of HMOs in A1-type β-casein-free formula on gut health, immunity, inflammation, gut microflora, cognitive development, and temperament compared with HMOs in conventional formula in…
- Trial name
- NCT07882043
- Testing
- a2 toddler milk with HMOs, Conventional toddler milk with HMOs
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- a2 Milk Company Ltd.
Postoperative Recovery in Children
Development and Validation of the Paediatric Scale for Quality of Recovery in the Post-Anaesthesia Care Unit
This project aims to develop and test a new questionnaire to measure how well children recover in the post-anaesthesia care unit (PACU).
- Trial name
- PedSQoR-PACU (NCT07610915)
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Mahidol University
Cerebral Palsy, Infant Development
Relationship Between Prenatal Maternal Distress and the Quality of General Movements at 3 Months
Depression and anxiety symptoms are common during pregnancy which may disturb the intrauterine environment by affecting the mother's physiological responses to stress, and ultimately impair fetal and postnatal development.
- Conditions
- Cerebral Palsy, Infant Development, Maternal Distress
- Trial name
- NCT05694676
- Testing
- Assessment of the quality of Genaral Movements (GMs), State-Trait Anxiety Inventory-Trait, (STAI-T), Beck Depression Inventory, (BDI)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Karamanoğlu Mehmetbey University
Social Anxiety Disorder (SAD), Autistic Disorder
Autism Traits in Adolescents With Social Anxiety Disorder: Associations With Parental Broader Autism Phenotype
This observational study aims to examine autism-related traits in adolescents diagnosed with social anxiety disorder (SAD) and to evaluate their associations with broader autism phenotype (BAP) features in their parents.
- Trial name
- NCT07106840
- Testing
- No intervention (observational study)
- Where
- Turkey (Türkiye)
- Volunteers
- 109 people
- Sponsor
- Ankara City Hospital Bilkent
Anxiety, Depression
Metacognitive Therapy for Common Mental Health Problems in Autistic CYP: A Case Series
Anxiety and Depression are common in young people (CYP) and especially in CYP with a diagnosis of Autism. Autistic people often say therapy has not been adapted to meet their needs.
- Trial name
- NCT05980143
- Testing
- Metacognitive Therapy
- Where
- 2 sites in United Kingdom
- Volunteers
- 5 people
- Sponsor
- University of Manchester
Solid Tumor, Adult
Development and Application Study of ePRO Software for Managing Cancer Patients Throughout the Treatment Period
After receiving chemotherapy, targeted therapy, immunotherapy and other drug treatments, tumor patients often experience various adverse reactions such as bone marrow suppression, diarrhea, pneumonia, etc.
- Trial name
- NCT06469268
- Testing
- Epro software
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shikai Wu
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