Clinical trials: H-reflex
Epilepsy, Seizure
Epileptiform Potential of Fully Immersive Virtual Reality
The goal of this interventional study is to determine if the use of virtual reality headsets results in an increased risk of seizure in adolescent and adult individuals with epilepsy.
- Trial name
- NCT07451093
- Testing
- Virtual Reality Headset, display off, Virtual Reality Headset, Display only, Virtual Reality Headset, Display and Hand Control
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Trigeminocardiac Reflex, Hemodynamic Changes
Association Between Lingual Retraction and Hemodynamic Changes in Patients Receiving Dental Treatment Under General Anesthesia
This study aims to investigate the association between sudden decreases in heart rate and blood pressure during dental procedures requiring lingual retraction-such as fillings, root canal treatments, tooth extractions, and cyst…
- Conditions
- Trigeminocardiac Reflex, Hemodynamic Changes, Dental Procedures
- Trial name
- NCT07240688
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Kırıkkale University
Gag Reflex, Child
Mucoadhesive Gels in Controlling Gag Reflex Among Children During Dental Radiographic Examination
This randomized clinical trial compares tannic acid-zinc acetate mucoadhesive gel with lidocaine gel for reducing gag reflex in children aged 8-10 years during radiographic dental examination Gag reflex severity and pulse rate…
- Trial name
- NCT07509918
- Testing
- Tannic Acid Mucoadhesive Gel (Topical), Zinc Acetate Mucoadhesive Gel (Topical), Lidocaine Gel (Topical)
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cairo University
Vestibulo-Ocular Reflex, Esports Participation
Comparison of Vestibulo-Ocular Reflex and Cognitive Functions in E-Athletes and Non-Athletes
This study aims to compare cognitive functions and functional vestibulo-ocular reflex (VOR) between e-athletes and non-athletes.
- Conditions
- Vestibulo-Ocular Reflex, Esports Participation, Cognitive Functioning
- Trial name
- NCT07211191
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Yusa Basoglu
Reflex Syncope
Cardioneuroablation: Comparison of Right Versus Left Atrial Approach in Patients With Reflex Syncope
Introduction. Reflex vaso-vagal syncope (VVS) is the most frequent cause of transient loss of consciousness and it's treatment remains a challenge.
- Trial name
- ROMAN2 (NCT05225532)
- Testing
- Radiofrequency ablation
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Centre of Postgraduate Medical Education
Photosensitive Epilepsy
Treatment of Sunflower Syndrome With ZX008 (Fenfluramine Hydrochloride) in Children and Young Adults (Ages 4-25).
Sunflower Syndrome (also referred to as Self-induced Photosensitive Epilepsy) is a rare epileptic disorder characterized by a distinctive seizure that manifests itself in a highly stereotyped physical behavior.
- Trial name
- NCT03790137
- Testing
- Fenfluramine Hydrochloride
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Elizabeth Anne Thiele
Reflex Epilepsy, Photosensitive, Eyeglasses
Efficacy of Lenses in Abolishing Photoparoxysmal Responses
Background. Blue lenses that filter out red light have been proposed as a new therapeutic alternative for patients with PSE, such as the lens Zeiss Clarlet Z1.
- Trial name
- PPRs (NCT04076410)
- Testing
- Z1 lens, Experimental Lens 1, Experimental Lens 2
- Where
- 2 sites in United Kingdom
- Volunteers
- 28 people
- Sponsor
- Aston University
Premature, Development, Child
Study of the Emergence of Sensory Self-awareness in Premature Newborns Using the Rooting Reflex
The main objective is to demonstrate the presence of the rooting reflex in premature and the emergence of sensory self-awareness in premature by showing a difference in the response of the rooting reflex to external tactile…
- Conditions
- Premature, Development, Child, Rooting Reflex
- Trial name
- PREMATACT (NCT06365164)
- Testing
- Tactile stimulation
- Where
- France
- Volunteers
- 19 people
- Sponsor
- University Hospital, Grenoble
Increased Lordosis/Scoliosis, Hyporeflexia
Biomarker for Duchenne Muscular Dystrophy
International, multicenter, observational, longitudinal study to identify biomarker/s for Duchenne Muscular Dystropy (DMD) and to explore the clinical robustness, specificity, and long-term variability of these biomarker/s.
- Conditions
- Increased Lordosis/Scoliosis, Hyporeflexia, Duchenne Muscular Dystrophy, Red-Green Color Blindness
- Trial name
- BioDuchenne (NCT02994030)
- Where
- 12 sites in Albania, Egypt and 6 more
- Volunteers
- 103 people
- Sponsor
- CENTOGENE GmbH Rostock
Brain Concussion, Reflex, Pupillary
Utility of Pupillary Metrics in Diagnosis and Management of Concussion in Children
The purpose of this study is to gather information and compare the potential use of pupillometry to identify concussions and post concussive syndrome with standard age appropriate assessments.
- Conditions
- Brain Concussion, Reflex, Pupillary, Post-Concussion Syndrome, Brain Injuries, Traumatic
- Trial name
- NCT04540445
- Testing
- Pupillary Assessment
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Orange County
Reflex, Oculocardiac
Cervical Vagus Nerve Block Prevents Ocularvagal Reflex
In ophthalmic surgery, surgical operations such as pulling certain eye tissues or compressing the eyeball often leads to bradycardia, arrhythmia even cardiac arrest, bradypnea, nausea and vomiting and elevated blood sugar level.
- Trial name
- NCT04950881
- Testing
- Ultrasound guided vagus nerve block, Bradycardia Treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
RSD (Reflex Sympathetic Dystrophy), CRPS - Complex Regional Pain Syndrome Type I
Adipose Stem/Stromal Cells in RSD, CRPS, Fibromyalgia
Reflex Sympathetic Dystrophy (RSD), Complex Regional Pain Syndrome (CRPS), Causalgia, and Fibromyalgia represent progressive systemic pain conditions which often worsen over time.
- Conditions
- RSD (Reflex Sympathetic Dystrophy), CRPS - Complex Regional Pain Syndrome Type I, Fibromyalgia
- Trial name
- ADcSVF-CRPS (NCT02987855)
- Testing
- Lipoaspiration, ADcSVF isolation, Normal Saline IV
- Where
- 2 sites in United States, Honduras
- Sponsor
- Healeon Medical Inc
Amplified Musculoskeletal Pain Syndrome, Reflex Sympathetic Dystrophy
Audio-Visual Relaxation Technology for Pediatric Amplified Musculoskeletal Pain Syndrome
A pilot randomized controlled trial to assess feasibility, acceptability and generate outcome domains for a future RCT testing the efficacy of immersive virtual reality on pain intensity in pediatric amplified musculoskeletal…
- Conditions
- Amplified Musculoskeletal Pain Syndrome, Reflex Sympathetic Dystrophy, Complex Regional Pain Syndromes
- Trial name
- NCT03762213
- Testing
- Oculus GO VR HMD, application Happy Place (© Mimerse), iPad, application Happy Place (© Mimerse)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Tufts Medical Center
Strabismus, Reflex, Oculocardiac
Hydroxyzine Dihydrochloride Premedication is a Necessity for Strabismus Surgery
Oculocardiac reflex (OCR) is usually happening in pediatric strabismus surgery and observed just when the surgent pulls the ocular muscles.
- Conditions
- Strabismus, Reflex, Oculocardiac, Hydroxyzine, Bradycardia Sinus
- Trial name
- NCT03806270
- Testing
- Midazolam, Hydroxyzine Dihydrochloride
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Yeditepe University
Reflex, Abnormal
Prepulse Inhibition in Youth Contact Sports Players
The study's main research question will be investigating whether or not there is a significant difference in Prepulse Inhibition (PPI) as well as startle response probability and magnitude between contact and noncontact youth…
- Trial name
- NCT04058184
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Photosensitive Epilepsy
Effect of Valproic Acid Concentration on Photic Response
We are trying to learn if small changes in the amount of a valproate in the blood (given through an IV) will change the way the brain reacts to flashing lights.
- Trial name
- NCT00609245
- Testing
- Valproic Acid
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- Vanderbilt University Medical Center
Premedication, Oculocardiac Reflex
Intranasal Dexmedetomidine vs Midazolam-ketamine Combination for Premedication of Pediatric Patients
The aim of this study is using intranasal dexmedetomidine versus intranasal midazolam-ketamine combination for premedication and preventing the oculocardiac reflex of pediatric patients undergoing strabismus surgery.
- Trial name
- NCT02072083
- Testing
- Dexmedetomidine, Ketamine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Healthy, Hyperalgesia
Positron Emission Tomography to Measure Pain and Pain Control
This study will examine how the brain processes pain signals and how the different parts of the brain work with each other in response to painful stimuli.
- Conditions
- Healthy, Hyperalgesia, Pain, Peripheral Nervous System Disease
- Trial name
- NCT00001307
- Testing
- Oxygen-15 Water, Capsaicin
- Where
- United States
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)