Clinical trials: HIV Seronegativity
HIV Infections, Sexually Transmitted Diseases
MEMA Kwa Vijana Trial: Impact of an Adolescent Sexual and Reproductive Health Intervention in Mwanza, Tanzania
The MEMA kwa Vijana Project is a community randomised trial which aims to assess the impact of a targeted intervention on adolescent sexual and reproductive health in Mwanza Region, Tanzania.
- Conditions
- HIV Infections, Sexually Transmitted Diseases, Pregnancy, Sexual Behavior
- Trial name
- NCT00248469
- Testing
- In-school Sexual Health Education, Youth-friendly health services, Youth condom promotion & distribution
- Where
- Tanzania
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Death, HIV Infection
Community-based Evaluation of a Pilot PMTCT Project in Kafue District
In this study, the investigators will assess the population effectiveness of using routine HAART as a PMTCT strategy, through a community-based survey.
- Trial name
- NCT00753428
- Testing
- Community-based Survey
- Where
- Zambia
- Volunteers
- 4,129 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
HIV Infections
HIV Prevention for Youth With Severe Mental Illness
This 4-year competing continuation will extend the follow-up for 750 subjects enrolled in a randomized interventions trial, Project STYLE: "HIV Prevention for Youth with Severe Mental Illness" (R01, MH 63008).
- Trial name
- NCT00496691
- Testing
- Family-based HIV prevention program
- Where
- United States
- Volunteers
- 718 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
HIV Infections, Sexually Transmitted Diseases
Efficacy of an Abstinence-Only HIV Risk-Reduction Intervention for Young African-American Adolescents
This study will develop and evaluate the effectiveness of culturally appropriate HIV/sexually transmitted disease risk-reduction interventions in reducing sexual risk behavior among young African-American adolescents.
- Trial name
- NCT00640653
- Testing
- Abstinence-only HIV/STD risk-reduction intervention, Safer-sex-only HIV/STD risk-reduction intervention, Long comprehensive HIV/STD risk-reduction intervention
- Where
- United States
- Volunteers
- 662 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
HIV Infections, Sexually Transmitted Disease
Effect of HIV/STD Risk Reduction Program on South African Adolescents
This study will evaluate the effect of an HIV/STD risk-reduction program on the sexual behavior of South African adolescents.
- Trial name
- NCT00559403
- Testing
- HIV/STD Risk-Reduction, Health Promotion
- Volunteers
- 1,057 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
HIV Infection, Tuberculosis
Daily Isoniazid to Prevent Tuberculosis in Infants Born to Mothers With HIV
Tuberculosis (TB) is highly endemic in sub-Saharan Africa. The increased burden of TB in settings with high prevalence of the Human Immunodeficiency Virus (HIV) is associated with high rates of transmission of Mycobacterium…
- Conditions
- HIV Infection, Tuberculosis, Pneumocystis Jiroveci Pneumonia
- Trial name
- NCT00080119
- Testing
- Isoniazid (INH), Trimethoprim/Sulfamethoxazole (TMP/SMX)
- Where
- 6 sites in Botswana, South Africa
- Volunteers
- 1,354 people, healthy volunteers welcome
- Sponsor
- International Maternal Pediatric Adolescent AIDS Clinical Trials Group
HIV Infections
Male Partner Involvement in the Prevention of MTCT of HIV
The study aims to invite male sexual partners to attend antenatal clinic with their pregnant partners to either acquire pregnancy information or undergo voluntary counselling and testing for HIV.
- Trial name
- NCT00405990
- Testing
- Voluntary counselling and HIV testing in ANC for PMTCT, VCT
- Where
- South Africa
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Imperial College London
HIV Infections
Hormonal Birth Control and the Risk of Acquiring HIV
The purpose of this study is to find out whether hormonal birth control increases, decreases, or does not change the risk of women becoming infected with HIV.
- Trial name
- NCT00006324
- Testing
- Ethinyl estradiol/levonorgestrel, Medroxyprogesterone acetate
- Where
- United States
- Volunteers
- 6,360 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
HIV Infections
Behavioral, Clinical and Basic Science Studies of Non-occupational Post-exposure Prophylaxis ("PEP-2")
This is a randomized trial to compare the effect of standard versus enhanced risk reduction counseling on risk behavior incidence in individuals receiving PEP medications.
- Trial name
- PEP-2 (NCT00473018)
- Testing
- standard versus enhanced risk reduction counseling
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
HIV Infections
C2P (With Venues): Connect to Protect® Partnerships For Youth Prevention Interventions
During Phase III, Adolescent Trials Network for HIV/AIDS Interventions (ATN)/Connect-to-Protect (C2P) site staff, their official community partners established in Phase I, and newly invited community sector representatives (i.e.…
- Trial name
- NCT00271908
- Testing
- Community Mobilization
- Where
- 8 sites in United States, Puerto Rico
- Volunteers
- 4,472 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
HIV Infections
Community Intervention Trial for Youth (CITY) Study
The purpose of this study is to test whether a multi-component, community-level, HIV-prevention intervention is more effective than existing HIV prevention activities in reducing unprotected anal intercourse (UAI) among men ages…
- Trial name
- NCT00164580
- Testing
- Community-Level Intervention
- Where
- 8 sites in United States
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
HIV Infections, HIV Seronegativity
Safety and Effectiveness of Two Different Formulations of an HIV Vaccine in Infants Born to HIV-Infected Women
The purpose of this study is to test the safety and effectiveness of two different formulations of an HIV vaccine in infants born to HIV-infected women.
- Trial name
- NCT00000809
- Testing
- Aluminum hydroxide, QS-21, MN rsgp120/HIV-1
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Sexually Transmitted Diseases, Pregnancy
All About Youth: Evaluation of Sexual Risk Avoidance and Risk Reduction Programs for Middle School Students
This study will evaluate the efficacy of two curricula relative to standard care. The first is a sexual risk avoidance curriculum for middle school students that included abstinence until marriage and complies with Title V…
- Conditions
- Sexually Transmitted Diseases, Pregnancy, HIV Infections
- Trial name
- NCT00167505
- Testing
- Risk Avoidance Intervention, Risk Reduction Intervention
- Where
- United States
- Volunteers
- 1,742 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Acquired Immunodeficiency Syndrome, HIV Infections
Analysis of Immune Responses to HIV Vaccines
This study will evaluate a test designed to measure immune system responses to HIV and HIV vaccines.
- Trial name
- NCT00068978
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Disease Transmission, Vertical, Vertical Human Immunodeficiency Virus Transmission
Trial of Three Neonatal Antiretroviral Regimens for Prevention of Intrapartum HIV Transmission
Giving anti-HIV medications to babies born of HIV positive mothers right after birth can lower the babies' risk of contracting HIV.
- Conditions
- Disease Transmission, Vertical, Vertical Human Immunodeficiency Virus Transmission, HIV Infections
- Trial name
- NCT00099359
- Testing
- Zidovudine, Nevirapine (NVP), Epivir (3TC)
- Where
- 17 sites in United States, Argentina and 3 more
- Volunteers
- 1,735 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
HIV Infections
HIV Prevention Preparedness Study in Russia, China, and India
The purpose of this study is to set up a system for doing research on HIV prevention in various parts of the world. In order to plan large, long-term studies on the prevention of HIV in different areas of the world, it is…
- Trial name
- NCT00021775
- Where
- 3 sites in China, Russia
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
Effectiveness of AZT and Nevirapine in Preventing HIV Transmission From Ugandan Mothers to Their Newborns
The purpose of this study is to see if nevirapine (NVP) or zidovudine (AZT), given to mothers during labor and delivery and to their babies during the first week of life, can reduce the rate of mothers passing HIV to their…
- Trial name
- NCT00006396
- Testing
- Nevirapine, Zidovudine
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Sexually Transmitted Diseases, HIV Infections
Group Prenatal Care for Reducing the Risk of STDs in Pregnant Young Women
This study will determine the effectiveness of two group prenatal care programs as compared to individual prenatal care in reducing the risk for HIV, STDs and adverse perinatal outcomes in young women during and after pregnancy.
- Trial name
- NCT00271960
- Testing
- CenteringPregnancy, CenteringPregnancyPlus, Usual care
- Where
- 2 sites in United States
- Volunteers
- 1,047 people, healthy volunteers welcome
- Sponsor
- Yale University
HIV Infections, Gender Based Violence
The Intervention With Microfinance for AIDS and Gender Equity (IMAGE) Study
The IMAGE Study is a cluster randomised trial of a structural intervention for the prevention of HIV and gender based violence being conducted in South Africa.
- Trial name
- NCT00242957
- Testing
- Intervention with Microfinance for AIDS and Gender Equity
- Where
- South Africa
- Volunteers
- healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Hiv
Evaluation of the Preventing AIDS Through Live Movement and Sound (PALMS) Intervention for Minority Adolescents
The purpose of this program evaluation is to determine whether the Preventing AIDS Through Live Movement and Sound (PALMS) group-level intervention is effective in reducing HIV sex risk behaviors and increasing HIV testing of…
- Trial name
- NCT00137644
- Testing
- Preventing AIDS Through Live Movement and Sound (PALMS)
- Where
- United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention