Clinical trials: INTENSIVE CARE
Digital Health, Maternal Health Services
The Effect of Digitally Enabled District (DED 2.0) Ecosystem on the Completeness and Timeliness of Maternal and Neonatal Services in Primary Health Care
DED 2.0 is a stepped-wedge cluster-randomized trial testing whether an integrated digital health ecosystem (KuApps, a service-monitoring dashboard, AI-assisted OCR for handwritten records, two-way WhatsApp-based health…
- Conditions
- Digital Health, Maternal Health Services, Prenatal Care, Intensive Care, Neonatal
- Trial name
- DED (NCT07842224)
- Testing
- Digitally Enabled District (DED)
- Where
- Indonesia
- Volunteers
- 10,800 people, healthy volunteers welcome
- Sponsor
- Summit Institute for Development, Indonesia
Delirium in the Intensive Care Unit, Sleep Quality in Adult ICU Patients
Virtual Reality to Reduce Anxiety, Agitation and Delirium in Critically Ill Patients
This is a pilot feasibility study examining the use of immersive virtual reality (VR) in adult intensive care unit (ICU) patients.
- Conditions
- Delirium in the Intensive Care Unit, Sleep Quality in Adult ICU Patients, Agitation Associated With Critical Illness, Anxiety Acute
- Trial name
- NCT07649876
- Testing
- Virtual reality (VR) therapy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Emotion Journal, Pediatric Intensive Care
Emotion Diary Application
Pediatric patients, hospitalization in a pediatric intensive care unit (PICU) is not merely a situation requiring physical treatment, but also an experience that has significant psychosocial effects.
- Conditions
- Emotion Journal, Pediatric Intensive Care, Emotion Regulation, Emotional Awareness
- Trial name
- NCT07860190
- Testing
- Emotion Diary Administration
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Gazi University
Preterm Birth, Very Preterm Infant
NICU-to-Home Dyadic Support for Very Preterm Infants and Families
This feasibility study will evaluate delivery of the Supporting Play Exploration and Early Development Intervention after neonatal intensive care unit discharge for very preterm infants and their families.
- Conditions
- Preterm Birth, Very Preterm Infant, Infant Development, Neonatal Intensive Care Unit
- Trial name
- MN-SPEEDI (NCT07820462)
- Testing
- Homebased SPEEDI, Telehealth SPEEDI
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Minnesota
Intensive Care (ICU)
An Investigation of The Relationship Between Muscle Mass, Physiological Parameters, and Blood Gas Levels in Adult Patients Hospitalized in The Intensive Care Unit
This study was designed to investigate the relationship between muscle mass and physiological parameters and blood gas values in adult patients admitted to the intensive care unit.
- Trial name
- NCT07866625
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Airway Clearance, Mechanical Insufflation-exsufflation
Mechanical Insufflation-Exsufflation in Critically Ill Patients
Mechanical insufflation-exsufflation (MI-E) is an established airway clearance technique for patients with chronic conditions like neuromuscular diseases.
- Conditions
- Airway Clearance, Mechanical Insufflation-exsufflation, Mechanical Insufflation-exsufflation Session ( With Cough Assist), Delphi Study
- Trial name
- DELMI-E (NCT07420946)
- Testing
- Delphi Questionnaire
- Where
- 4 sites in Italy, Spain and 1 more
- Volunteers
- 30 people
- Sponsor
- Medipol University
Child, Intensive Care Unit Acquired Weakness
Clinical Effectiveness of the "PICU Up!" Multifaceted Early Mobility Intervention for Critically Ill Children
While mortality in U.S. pediatric intensive care units (PICUs) is improving, surviving children frequently develop persistent physical, cognitive, and psychological impairments.
- Conditions
- Child, Intensive Care Unit Acquired Weakness, Critical Illness, Hospital Acquired Pressure Ulcer
- Trial name
- PICU Up! (NCT04989790)
- Testing
- PICU Up!
- Where
- 11 sites in United States
- Volunteers
- 1,470 people
- Sponsor
- Johns Hopkins University
Persistent Pulmonary Hypertension, Mechanical Ventilation Strategies
Pressure Regulated Volume Control Ventilation in Neonates Persistent Pulmonary Hypertension
This study aims to assess the clinical and respiratory outcomes of Pressure-Regulated Volume Control ventilation as compared with patient on pressure-controlled ventilation in neonates with persistent pulmonary hypertension.
- Conditions
- Persistent Pulmonary Hypertension, Mechanical Ventilation Strategies, Neonatal Intensive Care Unit (NICU), Ventilation
- Trial name
- NCT07850908
- Testing
- Pressure-Controlled Ventilation, Group II (Pressure-Regulated Volume Control)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Delirium in the Intensive Care Unit
Impact on Delirium of the Use of DEXmedetomidine as First-line Sedation in PEDIAtric Intensive Care
The goal of this clinical trial is to learn if dexmedetomidine can reduce delirium in critically ill children, needing mechanical ventilation for more than 12 hours.
- Trial name
- PEDIADEX (NCT07542990)
- Testing
- Dexmedetomidine, Midazolam
- Where
- 7 sites in France
- Volunteers
- 266 people
- Sponsor
- University Hospital, Tours
Pediatric Intensive Care Units
A Korean Point Prevalence Study of Acute Rehabilitation for Kids in the PICU (PARK-PICU)
This study investigates the prevalence of acute rehabilitation practices among children in pediatric intensive care units (PICUs).
- Trial name
- NCT07629297
- Testing
- Acute Rehabilitation (Observed Practice)
- Where
- 13 sites in South Korea
- Volunteers
- 396 people
- Sponsor
- Samsung Medical Center
Neonatal Intensive Care Unit (NICU)
Effects of TUMATA and Mozart Music on Sleep and Comfort in NICU Newborns
This study aims to evaluate the effects of two different types of music played in the neonatal intensive care unit on newborns' sleep and comfort levels.
- Trial name
- NeoMusic (NCT07837180)
- Testing
- TUMATA Music, Mozart Classical Music
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Intensive Care Unit, Mortality
Analysis of the Evolution of Mortality in an Intensive Care Unit
The intensive care units is of the main components of modern healthcare systems. Formally, its aim is to offer the critically ill health care fit to their needs; ensuring that this health care is appropriate, sustainable, ethical…
- Conditions
- Intensive Care Unit, Mortality, Epidemiology, Respiration, Artificial
- Trial name
- NCT05261607
- Where
- Spain
- Volunteers
- 27,463 people
- Sponsor
- Hospital Universitario Getafe
Systemic Lupus Erthematosus, Childhood-onset Systemic Lupus Erythematous
Gyrotonic Exercise in Lupus Adolescents Who Survived From Intensive Care
lupus adoelscented who recently survive from intenive care unit usually complain postintenive care unit syndrome in addition to stress, fatigue, low life quality, depression, low physical performance, low grip strenght, insomnia…
- Conditions
- Systemic Lupus Erthematosus, Childhood-onset Systemic Lupus Erythematous, Intensive Care Unit Survivors, Adolescents
- Trial name
- NCT07833020
- Testing
- Gryotonic exercise
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Critical Illness, Post Intensive Care Unit Syndrome
pEEG Monitoring Effect on Delirium, Ventilator Days, and PICS
The goal of this multi-site observational study is to compare delirium rates, days on mechanical ventilation, and Post Intensive Care Syndrome (PICS) rates in adult Intensive Care Unit (ICU) patients.
- Conditions
- Critical Illness, Post Intensive Care Unit Syndrome, Post Intensive Care Syndrome, Mechanical Ventilation Complication
- Trial name
- NCT06019078
- Testing
- SedLine
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Fraser Health
Premature, Neonatal Intensive Care Unit
The Effect of Gentle Human Touch and Stimulus Reduction on Pain and Comfort During Heel Blood Collection in Premature Newborns
Premature infants frequently experience painful procedures during their admission to neonatal intensive care units; this can lead to acute adverse events, imbalances, and long-term neurodevelopmental implications.
- Conditions
- Premature, Neonatal Intensive Care Unit, Touch, Nursing Care
- Trial name
- NCT07715682
- Testing
- Gentle Human Touch, Environmental Modification
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kubra Nur Kabakcı Sarıdağ
Mechanical Ventilation, Pulmonary Rehabilitation
Rehabilitation Practices in Critically Ill Patients Receiving Invasive Mechanical Ventilation in the Intensive Care Unit.
This international, multicenter, observational study aims to describe rehabilitation practices in Intensive Care Units (ICUs) worldwide.
- Conditions
- Mechanical Ventilation, Pulmonary Rehabilitation, Intensive Care Units (ICUs), Quality of Life (QOL)
- Trial name
- REPOrt (NCT07093125)
- Where
- Italy
- Volunteers
- 2,400 people
- Sponsor
- Universita degli Studi di Genova
Ventilator-Associated Pneumonia Prevention and Intensive Care Nursing Care
Theory-Based Educational Program for VAP Prevention and Nursing Care in Intensive Care Units
Ventilator-associated pneumonia (VAP) is an important challenge in intensive care and requires nurses to apply evidence-based preventive practices consistently in mechanically ventilated patients.
- Trial name
- TSEP-VAP-2026 (NCT07820826)
- Testing
- Theory-Based Structured Educational Program, Usual Care
- Where
- Jordan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- JAWAD AHMAD ABU-SHENNAR
Mechanically Ventilated Children Admitted to the Pediatric Intensive Care Unit
Impact of Sedation Practices on Clinical Outcomes Among Mechanically Ventilated Children
evaluate the impact of sedation adequacy on clinical outcomes in mechanically ventilated children admitted to the pediatric intensive care unit (PICU).
- Trial name
- ISPMVC (NCT07821268)
- Testing
- no need
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Yasmine Ahmed Abdelrahman
Premature, Phototherapy
Effectiveness of Aluminum Foil vs White Linen Reflectors in Phototherapy for Neonatal Hyperbilirubinemia
Background: Indirect hyperbilirubinemia (IHB) is a common neonatal condition, affecting over 60% of term and 80% of preterm infants.
- Conditions
- Premature, Phototherapy, Neonatal Intensive Care Unit, Neonatal Hyperbilirubinemia
- Trial name
- NCT07266246
- Testing
- reflective material
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Kubra Nur Kabakcı Sarıdağ
Neonatal Hypoglycemia, Metabolic Complication
Pasteurised Donor Human Milk Supplementation for Term Babies
PRESENT is a multi-center randomised controlled trial that aims to assess whether access to pasteurized donor human milk as supplementary nutrition in the first five days of life for term infants born to women with diabetes in…
- Conditions
- Neonatal Hypoglycemia, Metabolic Complication, Cows Milk Allergy, Hospital Length of Stay
- Trial name
- PRESENT (NCT06993103)
- Testing
- Standard care Cow's milk based formula, Dietary Supplement: PDHM Pasteurised Donor Human Milk
- Where
- 4 sites in Australia
- Volunteers
- 1,444 people
- Sponsor
- The University of Queensland