Clinical trials: Ileocolic Crohn Disease
Crohn Disease
Comparing Hand-sewn (END-TO-END or Kono-S) to Stapled Anastomosis in Ileocolic Resection for Crohn's Disease
The aim of this multicenter randomised controlled trial is to compare the handsewn (end-to-end and Kono-S) to the stapled side-to-side ileocolic anastomosis after ileocolic resection for Crohn's disease with respect to 6 months…
- Trial name
- END2END (NCT05578235)
- Testing
- stapled side-to-side anastomosis, Handsewn anastomosis
- Where
- Netherlands
- Volunteers
- 165 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Crohn Disease of Ileum
Ileocolic Resection for Complex Crohn's Disease
Laparoscopic ileocolic resection is the preferred surgical approach for patients with ileocecal Crohn's disease (CD). Objective of this study was to evaluate the efficacy of a minimally invasive gas-less ileocolic resection in…
- Trial name
- NCT03950726
- Testing
- ileocolic resection
- Volunteers
- 27 people
- Sponsor
- University of Roma La Sapienza
Crohn's Disease
Mesenteric SParIng Versus Central mesenterectomY in Ileocolic Resection for Terminal Ileitis in Crohn's Disease
The aim of this multicenter randomised controlled trial is to analyse the six month endoscopic recurrence following a mesenteric sparing versus a central mesenterectomy performing an ileocolic resection for CD.
- Trial name
- SPICY (NCT04538638)
- Testing
- Mesenteric sparing ileocolic resection, Central mesenterectomy ileocolic resection
- Where
- Netherlands
- Volunteers
- 139 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Endoscopic Recurrence Rate, After Ileocolic Crohn 's Disease Surgery
Mesenteric Surgical Margin for Crohn's Disease Endoscopic Recurrence
Despite significant advancements in the treatment of Crohn's disease (CD), approximately 50% of patients undergo surgical intervention within ten years of diagnosis.
- Trial name
- NCT06241170
- Testing
- mesentery-guided resection margin, traditional resection margin
- Where
- China
- Volunteers
- 172 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Inflammatory Bowel Disease, Crohn's Disease
The Role of Small Bowel Ultrasound in Initiation of Infliximab in Crohn's Disease Patients
Goal is to prospectively determine if stool calprotectin and change in bowel wall thickness and hyperemia, as seen on small bowel ultrasound, at week 0, 14, and 54 can be used to predict response at week 54 to infliximab in…
- Trial name
- NCT02330458
- Testing
- Small bowel ultrasound
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cedars-Sinai Medical Center
Crohn Disease, Surgery
Minimally Invasive Surgery in Crohn's Disease: Laparoscopic vs Robotic
Retrospective observational cohort study including patients with Crohn's Disease undergoing minimally invasive ileocolic resection.
- Trial name
- NCT05161442
- Volunteers
- 249 people
- Sponsor
- Mayo Clinic
Crohn's Disease, Recurrence
Crohn's Extent of Resection Trial
The trial will investigate if removing an additional length of small bowel will result in lower risk of recurrence at the surgical join (anastomosis), thereby decreasing the need for further surgery in the future.
- Trial name
- CERT (NCT01876264)
- Testing
- Extended resection, Conventional resection
- Where
- United Kingdom
- Sponsor
- Oxford University Hospitals NHS Trust