Clinical trials: Imaging Evaluation
LAMA2-MD (Merosin Deficient Congenital Muscular Dystrophy, MDC1A)
LAMA2-related Muscular Dystrophy Brain Study
Laminin alpha-2 (LAMA2)-related muscular dystrophy (LAMA2-MD, Merosin Deficient CMD) is a form of congenital muscular dystrophy (CMD).
- Trial name
- NCT01952028
- Where
- United States
- Sponsor
- Cure CMD
Congenital Cytomegalovirus Infection
Prognostic Value of Neonatal Markers for the Development of Neurosensorial Sequelae in Children Infected by Cytomegalovirus in Utero
The main objective of this study is to validate , in the neonatal period, a prognostic score for the development of neurosensorineural sequelae at 1 year and at 2 years in neonates infected in utero by cytomegalovirus.
- Trial name
- CYMEPEDIA (NCT01923636)
- Testing
- detection of CMV
- Where
- France
- Volunteers
- 254 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
To Assess the Feasibility, Visualization Capability, and Optimal Dosing of ICG Fluorescence Imaging for Intraoperative Assessment of Knee Tissue Perfusion
ICG Fluorescence in Knee Arthroscopy Study
The purpose of this study is to first evaluate whether ICG fluorescence angiography can be used to evaluate blood flow of the anterior cruciate ligament (ACL), tendons, and knee structures during an arthroscopic surgery.
- Trial name
- NCT07793266
- Testing
- Intravenous administration of indocyanine green (SPY Agent Green) 2 mL of SPY Agent Green (5.0 mg dose), Intravenous administration of indocyanine green (SPY Agent Green) 3 mL of SPY Agent Green (7.5 mg dose), Intravenous administration of indocyanine green (SPY Agent Green) 4 mL of SPY Agent Green (10 mg dose)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Henry Ford Health System
Brain Injuries, Malaria
An MRI Ancillary Study of a Malaria Fever Investigation
This study will seek consent from parents of children enrolled in the Malaria FEVER study to obtain neuroimaging and 12-month neuropsychiatric outcomes data and kidney function on their child.
- Conditions
- Brain Injuries, Malaria, MRI Imaging, Neurocognitive Deficits
- Trial name
- MRIA (NCT05746819)
- Testing
- Aggressive antipyretics therapy of fever vs usual care in the Malaria RCT study
- Where
- 2 sites in Malawi, Zambia
- Volunteers
- 181 people
- Sponsor
- University of Rochester
Arterial Switch Operation
Multimodal Imaging Evaluation and Prognostic Analysis of Participants After Arterial Switch Operation
The aims of this study are to 1. Identify the early and midterm outcomes in terms of mortality and reoperation of the arterial switch operation (ASO). 2.
- Trial name
- NCT04980339
- Volunteers
- 1,000 people
- Sponsor
- Xie Mingxing
Device:MRI
Magnetic Resonance Imaging (MRI) in Patients With Pacemakers and Implanted Cardioverter Defibrillators
Ferromagnetic Implants such as permanent pacemakers (PPM's) and Implantable Cardioverter Defibrillators (ICD's) have traditionally been accepted as contraindications to Magnetic Resonance Imaging (MRI) due to safety concerns.
- Trial name
- NCT02888353
- Testing
- Device: MRI
- Where
- United States
- Volunteers
- 4,500 people
- Sponsor
- Johns Hopkins University
Posterior Brain Fossa Tumors in Children
Feasibility of 11C-MET PET/MRI Imaging in Pediatric Brain Fossa Tumors
Brain tumors are the most common solid tumors in children and are the second most common cause of cancer-related death among this population. Posterior brain fossa tumors represent about 50% of children brain tumors.
- Trial name
- TI-TFCE (NCT03977896)
- Testing
- 11C-MET PET/MRI
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Hospices Civils de Lyon
Primary Graft Failure
REVEAL Biomarkers of Engraftment After Alternative Donor HSCT
The purpose of this study is to find new tests that could help determine if the newly infused bone marrow cells are growing well after bone marrow transplantation or if new bone marrow cells are needed.
- Trial name
- REVEAL (NCT03541889)
- Testing
- FLT imaging and TK1 blood measurements
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of Oklahoma
Meniscus Lesion
Muskloskeletal Ultrasound Versus Magnetic Resonance Imaging in Meniscal Abnormalities
clinical examination alone is usually insufficient in assessment of knee meniscus and a more reliable diagnosis can be achieved by using the knee ultrasound , magnetic resonance imaging.
- Trial name
- NCT03490799
- Volunteers
- 30 people
- Sponsor
- Assiut University
Cervical Cancer, Endometrial Cancer
Pelvic Fractures and Radiation Therapy for Cervical Cancer
The goal of this study is to estimate how often pelvic fractures occur in women treated with radiation therapy for either newly diagnosed or recurrent cervical, endometrial, or vaginal cancer.
- Conditions
- Cervical Cancer, Endometrial Cancer, Vaginal Cancer
- Trial name
- NCT00800644
- Testing
- CT or MRI + Blood Test
- Where
- United States
- Volunteers
- 239 people
- Sponsor
- M.D. Anderson Cancer Center
Osteoarthritis Knee
Effectivity of Allogenic Umbilical Cord Mesenchymal Stem Cells Conditioned Media for Osteoarthritis of the Knee Joint
Osteoarthritis (OA) is a joint disorder that often occurs and causes disability. This disorder is characterized by an inflammatory reaction in the synovial joints accompanied by a gradual degeneration process in the articular…
- Trial name
- NCT06688318
- Testing
- Intra-articular secretome injection therapy
- Where
- Indonesia
- Volunteers
- 11 people
- Sponsor
- Kementerian Riset dan Teknologi / Badan Riset dan Inovasi Nasional, Indonesia
Chronic Intestinal Pseudo-Obstruction
Pseudo-obstruction Assessment With MRI
This study will explore the potential for a standardized MRI scan after a liquid meal to be used in diagnosis of the rare but debilitating chronic intestinal pseudo-obstruction (CIPO).
- Trial name
- POM (NCT04193735)
- Testing
- MRI scans after a liquid meal
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- University of Nottingham
Epilepsy
Evaluation of Functional MRI and DTI (Imaging Techniques) in Children With Epilepsy and Focal Brain Lesions
This study is being done to look at the relationship between brain structure and brain function in patients with epilepsy or focal brain lesions (abnormal areas) that require surgery.
- Trial name
- NCT00229840
- Testing
- Functional MRI, Diffusion Tensor Imaging
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's Healthcare of Atlanta
Chronic Kidney Disease
Non-Invasive Evaluation of Transplant Kidney Using OCT
Optical coherence tomography (OCT) is a rapidly emerging imaging modality that can function as a type of "optical biopsy", providing non-invasive cross-sectional images of tissue architectural morphology in situ and in real-time.
- Trial name
- NCT02084966
- Testing
- Procedure/Surgery: Transplantation: OCT of Kidney Transplant
- Where
- United States
- Volunteers
- 169 people
- Sponsor
- Georgetown University
Cancer
Development of Computer-aided Detection and Diagnosis From Imaging Techniques
This study will develop and evaluate new techniques for computer-aided detection and diagnosis (CAD) of medical problems using images from diagnostic tests such as computed tomography (CT), ultrasound, nuclear medicine and x-ray…
- Trial name
- NCT00057252
- Where
- United States
- Volunteers
- 139,692 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Magnetic Resonance Imaging
Magnetic Resonance Imaging of the Liver in Children 0-2 Months of Age With an Intravenous Injection of Eovist/Primovist Which is a Contrast Agent
This is an open-label, multi-center study involving babies 0-2 months of age who have liver problems (pathology) and need to have their liver and possibly, the bile ducts imaged using magnetic resonance imaging and injection of a…
- Trial name
- NCT02084628
- Testing
- Gadoxetate disodium (Eovist/Primovist, BAY86-4873)
- Where
- 9 sites in United States
- Volunteers
- 1 people
- Sponsor
- Bayer
Perianal Fistula
Role of MRI in Perianal Fistula
The aim of this study is to assess the diagnostic accuracy of MRI in detecting and assessment the primary fistulous tract, internal openings, secondary extensions, and associated abscesses.
- Trial name
- MRI PA fistula (NCT07510204)
- Testing
- Diagnostic imaging (MRI)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Developmental Dyslexia
Using fMRI to Evaluate Instructional Programs for Children With Developmental Dyslexia
Dyslexia is a common reading disorder. Specialized instructional programs can improve reading ability in children with dyslexia.
- Trial name
- NCT00068835
- Testing
- Lindamood-Bell training for dyslexia
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Kidney Failure
Application and Impact Assessment of Ultrasound Super-Resolution Blood Flow Imaging (URM) in Patients With Renal Failure
The aim of this study is to evaluate the utility of URM technology in imaging renal microcirculatory blood flow in patients with renal failure, and to investigate its clinical feasibility for assessing renal function, disease…
- Trial name
- URM (NCT07484308)
- Testing
- Ultrasound super-resolution blood flow imaging
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Ma Zhe
Chronic Wounds, Obliterating Arteriopathy of the Lower Limbs
Clinical Evaluation of an Innovative Non-contact Optical Device for Skin Oxygenation Imaging
According to international consensus, information on the level of skin oxygenation is necessary for the diagnostic management of chronic wounds.
- Trial name
- IMOXY (NCT05187676)
- Testing
- Oxygen saturation measurement using the IPAM device, Transcutaneous oxygen partial pressure (TcPO2) using the PeriFlux6000 device
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Central Hospital, Nancy, France