Clinical trials: Incision Infection
Hydrocephalus, Ventriculoperitoneal Shunt Infection
Efficacy and Cost-Effectiveness of Topical Vancomycin Powder in Preventing Pediatric Ventriculoperitoneal Shunt Infections Across Different Etiologies
Objectives Primary: To measure the reduction in VP shunt infection rates using topical vancomycin powder. Secondary: To compare efficacy across different Etiological Strata (Congenital, Post-hemorrhagic, post-inflammatory).
- Conditions
- Hydrocephalus, Ventriculoperitoneal Shunt Infection, Surgical Site Infection (SSI), Cerebrospinal Fluid Shunt Infection
- Trial name
- NCT07547826
- Testing
- Topical Vancomycin Powder, Standard Perioperative Care
- Where
- Egypt
- Volunteers
- 164 people
- Sponsor
- Assiut University
Surgical Site Infection
Subcutaneous Tissue Irrigation With Povidone Iodine in Decreasing the Rate of Surgical Site Infection Following Cesarean Section
This study aims to assess the efficacy of Povidone Iodine (Betadine®) irrigation of subcutaneous tissue prior to skin closure in reducing the incidence of surgical site infection after elective caesarean section and post…
- Trial name
- NCT03549702
- Testing
- Povidone iodine 1% solution
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Cruciate Ligament Reconstruction Infection, Septic Arthritis
A Metagenomic Next-generation Sequencing (mNGS)-Guided Sequential Culture Strategy for Postoperative Cruciate Ligament Reconstruction Infection (CLRI): a Retrospective Cohort Study
This retrospective cohort study evaluates a sequential diagnostic strategy for patients with postoperative cruciate ligament reconstruction infection (CLRI).
- Conditions
- Cruciate Ligament Reconstruction Infection, Septic Arthritis, Surgical Wound Infection, Joint Infection
- Trial name
- NCT07852598
- Testing
- Metagenomic next-generation sequencing (mNGS), mNGS-guided modified culture, Conventional microbiological culture
- Where
- China
- Volunteers
- 80 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Surgical Site Infection
Effect of Peritoneal Lavage With Clindamycin-gentamicin Solution on Postoperative Colorectal Cancer Infection in Elective Surgery
Intrabdominal antibiotic irrigation will reduce wound and intrabdominal infection.
- Trial name
- lavage (NCT01378832)
- Testing
- Intra-peritoneal antibiotic lavage
- Volunteers
- 102 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Surgical Site Infections
Effect of Cefazolin and Normal Saline Irrigation on Surgical Site Infections (SSIs)
This study conducted to assess the effects of normal saline or cefazolin irrigation on the incidence of SSIs. Hypothesis: Normal saline or cefazolin irrigation decreases the incidence of SSIs.
- Trial name
- NCT01566734
- Testing
- Cefazolin irrigation, Normal Saline Irrigation
- Where
- Iran
- Volunteers
- 200 people
- Sponsor
- Hormozgan University of Medical Sciences
Abscess
Management of Skin and Soft Tissue Abscesses in Pediatric Patients After Incision and Drainage
The purpose of the study is to compare rates of cure of abscesses with and without antibiotic treatment after incision and drainage.
- Trial name
- NCT00691600
- Testing
- oral trimethoprim/sulfamethoxazole
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Baylor College of Medicine
Supracondylar Humerus Fracture, Post Operative Wound Infection
Antibiotics Usage in Pediatric Orthopaedic Percutaneous Surgery (APOPS)
The aim of this study is to determine if antibiotics affect the outcome after percutaneous surgery for pediatric supracondylar humerus fractures.
- Trial name
- NCT03261830
- Testing
- Cefazolin, Clindamycin, Saline
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Sumit Gupta
Abscess Soft Tissue, Methicillin-resistant Staphylococcus Aureus (MRSA) Infection
Randomized Controlled Trial of Antibiotics in the Management of Children With Community-Acquired Abscess
The purpose of this study is to better understand why children develop methicillin-resistant Staphylococcus aureus (MRSA) skin infections that require surgical drainage and whether antibiotics are helpful after the infection is…
- Conditions
- Abscess Soft Tissue, Methicillin-resistant Staphylococcus Aureus (MRSA) Infection, Skin Abscess
- Trial name
- NCT01498744
- Testing
- Oral Clindamycin
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Full-thickness Skin Defects, Degloving Injuries
RECELL® System Combined With Meshed Autograft for Reduction of Donor Skin Harvesting in Soft Tissue Reconstruction
A prospective randomized within-subject controlled study to compare the clinical performance of conventional autografting with and without the RECELL system on acute non-burn full-thickness skin defects.
- Conditions
- Full-thickness Skin Defects, Degloving Injuries, Crush Injuries, Laceration of Skin
- Trial name
- NCT04091672
- Testing
- Control Intervention (Conventional Autograft), Investigational Intervention (RECELL + more widely meshed autograft)
- Where
- 18 sites in United States
- Volunteers
- 65 people
- Sponsor
- Avita Medical
Surgical Site Infection
The Impact of Using Triclosan-antibacterial Sutures on the Incidence of Surgical Site Infection
To compare conventional polyglactin 910 sutures with triclosan-coated polyglactin 910 antimicrobial sutures for the reduction of surgical site infections and any associated health and economic benefits.
- Trial name
- NCT01019447
- Testing
- Vicryl Plus, Vicryl
- Where
- 2 sites in Egypt
- Volunteers
- 701 people
- Sponsor
- Cairo University
Operation Wound; Infection, Endometritis
Use of Antiseptic Solution for Vaginal Wash Before Cesarean Section
To evaluate the rate of infections after cesarean sections in patients with premature rupture of membranes after vaginal wash either with an antiseptic solution (clorhexidine solution) vs. saline solution (placebo).
- Trial name
- NCT03442218
- Testing
- Clorhexidine, Saline solution
- Where
- Panama
- Volunteers
- 203 people
- Sponsor
- Saint Thomas Hospital, Panama
Surgical Site Infections
St. Barbara Specialised Regional Hospital No. 5: Surveillance of Healthcare-Associated Infections
Retrospective laboratory-based data collection study of surgical site infections: Surveillance of Healthcare-Associated Infections in Orthopaedic and Trauma Surgery Unit in Sosnowiec, Poland;
- Trial name
- NCT03686553
- Testing
- laboratory-based data collection
- Volunteers
- 5,239 people
- Sponsor
- Polskie Towarzystwo Zakażeń Szpitalnych
Surgical Wound Infection, Cesarean Section
Preventing Adverse Incisional Outcomes at Cesarean Multicenter Trial
The Prophylactic Negative Pressure Wound Therapy in Obese Women at Cesarean Trial is a large pragmatic multi-center randomized clinical trial designed to evaluate the effectiveness, safety and cost-effectiveness of prophylactic…
- Trial name
- Prevena-C (NCT03009110)
- Testing
- Prophylactic NPWT, Standard Dressing
- Where
- 6 sites in United States
- Volunteers
- 1,624 people, healthy volunteers welcome
- Sponsor
- Indiana University
Surgical Site Infection
The Inselspital Surgical Cohort Study
Personalizing surgical care is of enormous clinical relevance, when considering the number of patients undergoing surgery in Switzerland every year.
- Trial name
- InSurg (NCT04096885)
- Testing
- Blood and urine samples, skin and stool swabs
- Where
- Switzerland
- Volunteers
- 1,226 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Obesity, Infection; Cesarean Section
Skin Incisions and Wound Complication Rates for C-sections in Obese Women
It is the purpose of this study to evaluate the relationship between a low transverse, vertical midline, and supra-panicular high transverse skin incisions and the rate of wound complications in women with a BMI of 40 or greater…
- Conditions
- Obesity, Infection; Cesarean Section, Surgical Wound
- Trial name
- NCT02685761
- Testing
- Midline Vertical, High Transverse
- Where
- 7 sites in United States
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Surgical Wound Infection, Cesarean Section
Effect of Intranasal Mupirocin on Rate of Staphylococcus Aureus Surgical Site Infection Following Cesarean Sections
The investigators believe that irradication of nose colonization of staphyloccocus aureus will reduce the incidence of surgical site infections after cesarean section.
- Conditions
- Surgical Wound Infection, Cesarean Section, Staphylococcus Aureus
- Trial name
- NCT01152593
- Testing
- Mupirocin
- Where
- Israel
- Volunteers
- 400 people
- Sponsor
- Hillel Yaffe Medical Center
Wound Infection, Wound Dehiscence
Honey Dressing - A Preventive Procedure for Post-Surgical Site Infection.
The goal of this clinical trial is to compare the wound healing in the participants who underwent the clean surgical procedure, by applying honey dressing and common Iodine solution dressing, participants will have no other…
- Conditions
- Wound Infection, Wound Dehiscence, Wound Bleeding, Wound Surgical
- Trial name
- NCT06220344
- Testing
- Honey Dressing, Iodine Dressing
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- HITEC-Institute of Medical Sciences
Orthopaedic Surgery (30 Minutes or Longer)
The Effect of Plasma-air-filtration on the Incidence of Surgical Site Infections in Orthopaedic Surgery
The study is a multicenter, double-blind, randomized, controlled trial conducted at six major university and teaching hospitals with a catchment population of approximately 2 million.
- Trial name
- EPOS (NCT02695368)
- Testing
- Novaerus NV800 on, Novaerus NV800 off, Novaerus NV800 on or off
- Where
- Sweden
- Volunteers
- 45,000 people
- Sponsor
- Karolinska Institutet
Abscess, Pain
IN Ketamine Vs IN Midazolam and Fentanyl for Abscess I&D
The general objective of this study is to determine whether intranasal ketamine should be incorporated into formulary as an option to treat pain during minor procedures in the pediatric emergency department.
- Trial name
- NCT02635282
- Testing
- intranasal ketamine, intranasal fentanyl, intranasal midazolam
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Surgical Scrubbing, Surgical Site Infection
Surgical Hand Scrubbing Methods and the Duration of Scrubbing Time
Surgical hand scrubbing is the removal of transient flora and reduction of permanent flora as much as possible before any sterile gloves are worn before any surgical intervention.
- Trial name
- NCT04579705
- Testing
- Using a brush
- Where
- Turkey (Türkiye)
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi