Clinical trials: Information Systems
Sickle Cell Disease
Development and Evaluation of an Information Management System and Communication System for Population-wide Point-of-care Infant Sickle Cell Disease Screening
Although over 75% of children with sickle cell disease (SCD) are born in sub-Sahara where the disease highly contributes to under-5 mortality and causes life-long debilitation, evidence-based strategies to control SCD are not…
- Trial name
- SIMCS SCD (NCT06563440)
- Testing
- Digital app and information system
- Where
- 2 sites in United States, Uganda
- Volunteers
- 24,000 people, healthy volunteers welcome
- Sponsor
- Makerere University
Health Systems, Electronic Community Health Information Systems
Digital Data Linkage and Scheduling to Track Pregnancy With or Without Community Data Use to Increase Antenatal Clinic Uptake in Western Kenya.
The investigators propose to increase ANC uptake through a health systems strengthening approach that links digital data platforms and trains community Work Improvement Teams (WITs) to use these data to identify problems and come…
- Conditions
- Health Systems, Electronic Community Health Information Systems, Antenatal Clinic Uptake, Pregnancy
- Trial name
- C-it-DU-it (NCT05929586)
- Testing
- The combined "C-it DU-it" intervention: community data use for ANC
- Where
- Kenya
- Volunteers
- 1,440 people, healthy volunteers welcome
- Sponsor
- Liverpool School of Tropical Medicine
Cleft Lip and Palate
Methods of Providing Information Prior to an Alveolar Bone Graft
Patients born with a cleft of the lip and/or palate may have a gap in the bone in the roof of their mouth and in the area of bone where the teeth develop.
- Trial name
- NCT04381078
- Testing
- ACE - AudioVisual Guide
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Cerebral Palsy
Optimizing Assisted Communication Devices for Children With Motor Impairments Using a Model of Information Rate and Channel Capacity
For children who depend on devices to communicate, the rate of communication is a primary determinant of success. For children with motor impairments, the rate of communication may be limited by inability to contact buttons or…
- Trial name
- NCT00352326
- Testing
- reprogramming assisted communication device interface
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Polycystic Ovary Syndrome
The PCOS Challenge Study
The primary purpose of The PCOS Challenge Study will be to conduct high-quality research where patients are included in the design, and answering the questions that patients identify as important to their lived experience with…
- Trial name
- PCOSCHALLENGE (NCT05797909)
- Where
- United States
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- PCOS Challenge: The National Polycystic Ovary Syndrome Association
ADHD
Initial Validation of the Vanderbilt ADHD Measure for Adolescent Patients in the ICISS Project
This proposal is to evaluate the reliability and validity of the Vanderbilt ADHD screening tool for use with adolescents and young adults aged 13-21 years.
- Trial name
- NCT01964209
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Behavior
Data-Informed Platform for Health (DIPH)
The overall aim of the Data-Informed Platform for Health (DIPH) is to improve Maternal, Newborn and Child Health (MNCH) programmes and services at the district level.
- Trial name
- NCT05310682
- Testing
- Data informed Platfrom for health
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Infections, Papillomavirus
Cervarix Long-term Safety Surveillance
This study aims to assess whether the use of Cervarix® is associated with a modified risk of central demyelination, type 1 diabetes (DT1), Cutaneous Lupus, inflammatory arthritis, idiopathic thrombocytopenic purpura (ITP), Lupus…
- Trial name
- PGRx (NCT01498627)
- Testing
- Cervarix, Data collection
- Volunteers
- 2,945 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
no Obvious Abnormalities, Diabetic Retinopathy (DR)
Retinal Clinical Assessment With AI-derived Quantitative Information
This randomized controlled trial evaluates whether providing clinicians with AI-derived quantitative retinal information improves the quality and efficiency of retinal clinical assessment.
- Conditions
- no Obvious Abnormalities, Diabetic Retinopathy (DR), AMD, Cup-to-disc Ratio Bigger Than 0.5
- Trial name
- NCT07291960
- Testing
- AI-derived retinal quantitative information-assisted reporting
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Leukemia, Lymphoma
A Novel Health Information Technology System (BMT Roadmap) for Pediatric BMT Patients and Caregivers
Hematopoietic cell transplantation (BMT), or commonly referred to as blood and marrow transplantation (BMT), is a potentially life-saving therapy for many malignant and non-malignant conditions.
- Conditions
- Leukemia, Lymphoma, Brain Tumor
- Trial name
- NCT02409121
- Testing
- Education information system
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Michigan Rogel Cancer Center
Asthma, Adolescent Behavior
The Effectiveness of Peer-education Programs for Adolescents Diagnosed With Asthma
The research was planned in a randomized controlled trial to evaluate the effect of technology-based education provided by peers and adults to children diagnosed with asthma in the 14-17 age group.
- Conditions
- Asthma, Adolescent Behavior, Self Efficacy, Peer Support and Chronic Disease
- Trial name
- NCT06392490
- Testing
- Technology Based Asthma Program
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Language Development Disorders
Memorisation of Phonologic Information Among Children With Oral Language Developement Disorder
The disorder of oral language development is defined by the delay in language acquisition in children who possess efficient auditory acuity and normal non verbal intellect.
- Trial name
- MEMENTO (NCT02609542)
- Testing
- Eye Tracking
- Where
- France
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Lille Catholic University
Digital Health, Maternal Health Services
The Effect of Digitally Enabled District (DED 2.0) Ecosystem on the Completeness and Timeliness of Maternal and Neonatal Services in Primary Health Care
DED 2.0 is a stepped-wedge cluster-randomized trial testing whether an integrated digital health ecosystem (KuApps, a service-monitoring dashboard, AI-assisted OCR for handwritten records, two-way WhatsApp-based health…
- Conditions
- Digital Health, Maternal Health Services, Prenatal Care, Intensive Care, Neonatal
- Trial name
- DED (NCT07842224)
- Testing
- Digitally Enabled District (DED)
- Where
- Indonesia
- Volunteers
- 10,800 people, healthy volunteers welcome
- Sponsor
- Summit Institute for Development, Indonesia
Vaccine, Human Papiloma Virus Vaccine
State Immunization Information Systems to Improve HPV Vaccination Rates
The overarching goal of this study is to evaluate the effectiveness, cost-effectiveness and sustainability of utilizing statewide Immunization Information Systems (IIS) to conduct centralized reminder/recall (R/R) to improve…
- Conditions
- Vaccine, Human Papiloma Virus Vaccine, HPV Vaccine, Immunization
- Trial name
- NCT02993965
- Testing
- Vaccine Reminder/Recall
- Where
- United States
- Volunteers
- 77,716 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Medication Adherence, Cystic Fibrosis
Interactive Mobile Health Information to Enhance Patient Care at a Cystic Fibrosis Center
Real-world adherence to inhaled and oral therapies for cystic fibrosis (CF) patients remains discouragingly low, ranging between 31-53% for inhaled antibiotics and 41-72% for hypertonic saline.
- Trial name
- MOMMI3CFCM (NCT03052231)
- Testing
- caremessage
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Landon Pediatric Foundation
Pancreatic Cancer
Using Digestive Microbial Information to Enhance the Early Detection of Pancreatic Cancer
Pancreatic cancer (PCA) is a leading death-related cancer. There is an urgent need for accurate, noninvasive diagnostic options in the early detection of pancreatic cancer (PCA), since delayed diagnosis increases the risk of…
- Trial name
- NCT05689138
- Testing
- Oral and Fecal Sample Collection
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Leukemia, Acute, Leukemia, Lymphoblastic
The SMART CART Study: Health Information Technology
This study evaluates the feasibility of using two information technology tools in patients undergoing Chimeric Antigen Receptor T-cell (CART) therapy and other Cytokine Release Syndrome (CRS)-eliciting treatments such as CD123…
- Trial name
- NCT04051216
- Testing
- Education information system, Activity monitor, Interview
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- University of Michigan Rogel Cancer Center
Acellular Pertussis, Diphtheria
Post-marketing Surveillance to Assess the Safety of Infanrix-IPV Vaccine Among Infants and Children in Korea
The purpose of this study is to collect safety information following routine vaccination with Infanrix-IPV among infants and children in Korea.
- Conditions
- Acellular Pertussis, Diphtheria, Tetanus, Poliomyelitis
- Trial name
- NCT01568060
- Testing
- Infanrix-IPV data collection
- Where
- South Korea
- Volunteers
- 645 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Disorder of Sex Development, Intersex Conditions
Decision Support for Parents Receiving Information About Child's Rare Disease
The birth of a child with a disorder of sex development (DSD) is stressful for parents and members of the healthcare team. The "right" decisions about gender assignment (is it a boy? a girl?) and the best course of action (e.g.…
- Conditions
- Disorder of Sex Development, Intersex Conditions, Congenital Adrenal Hyperplasia, Hypospadias
- Trial name
- DSD DST (NCT01875640)
- Where
- 4 sites in United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Blindness
Visual Information Restoration and Rehabilitation Via Sensory Substitution Technology in Children
The BrainPort vision device is a visual prosthetic designed for those who are blind. It enables perception of visual information using the tongue and camera system as a paired substitute for the eye.
- Trial name
- NCT03002597
- Testing
- BrainPort V200 Device
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Ellen Mitchell