Clinical trials: Inpatient
Penicillin Allergy, Penicillin Sensitivity
Inpatient Penicillin Allergy Delabeling Study
The study will identify pediatric patients 3-18 years old who have penicillin allergy label in the electronic medical record. Those who are identified will be stratified into no-risk, low-risk and high-risk category using a…
- Conditions
- Penicillin Allergy, Penicillin Sensitivity, Penicillin Reaction, Penicillin Intolerance
- Trial name
- NCT05020327
- Testing
- Graded Oral Amoxicillin Challenge, De-labelling in electronic medical record, Referral to Allergy Immunology/Retention of Allergy Label
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Early Ambulation
Implementing a Hospital-Based Walking Program (STRIDE): Function QUERI 2.0
Implementing a Hospital-Based Walking Program (STRIDE): Function QUERI 2.0 aims to compare implementation strategies for large-scale spread of STRIDE, a supervised walking program for hospitalized older Veterans.
- Trial name
- STRIDE (NCT04868656)
- Testing
- Implementation Strategy: Foundational Support, Implementation Strategy: Enhanced Support
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- VA Office of Research and Development
Pneumonia
Amoxicillin Versus Benzyl Penicillin for Treatment of Children Hospitalised With Severe Pneumonia
This study seeks to determine whether clinical outcome following initial treatment of severe pneumonia with oral amoxicillin is as effective as the current standard benzyl penicillin.
- Trial name
- NCT01399723
- Testing
- Amoxicillin, Benzyl penicillin
- Where
- 6 sites in Kenya
- Volunteers
- 561 people
- Sponsor
- KEMRI-Wellcome Trust Collaborative Research Program
HPV Vaccination
Evaluation of the Implementation and Effectiveness of IPP-HPV
The purpose of the proposed pilot study is to assess the implementation of IPP-HPV immunization at Yale New Haven Hospital (YNHH) and to identify potential barriers to and facilitators of this intervention to optimize its…
- Trial name
- NCT02994290
- Testing
- HPV vaccine, Inpatient Postpartum HPV Immunization Quality Improvement Program
- Where
- United States
- Volunteers
- 817 people
- Sponsor
- Yale University
Firearm Safety
Pediatric Inpatient Firearm Safety Study
There is currently no available data regarding using the inpatient setting as an opportunity to talk to parents/guardians about firearm safety.
- Trial name
- IF (NCT03077646)
- Testing
- Be SMART, Control: TSE, Be SMART + MD review
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Montefiore Medical Center
COVID-19, Diagnostic Test
Inpatient COVID-19 Lollipop Study
This study is being done to see if collecting saliva samples with a "lollipop" collection method works as well as nasopharyngeal samples for COVID-19 polymerase chain reaction (PCR) testing.
- Trial name
- NCT05801341
- Testing
- Lollipop
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Wisconsin, Madison
Gram-Positive Infections
A Pharmacokinetic Study of Tedizolid Phosphate in Pediatric Participants With Gram-Positive Infections (MK-1986-014)
The primary objectives of this study are to describe the single-dose, and multiple dose pharmacokinetics (PK) of intravenous (IV) tedizolid phosphate, or a single dose oral suspension of tedizolid phosphate, when administered to…
- Trial name
- NCT03217565
- Testing
- IV Tedizolid Phosphate, Oral Suspension Tedizolid Phosphate
- Where
- 30 sites in United States, Bulgaria and 3 more
- Volunteers
- 47 people
- Sponsor
- Merck Sharp & Dohme LLC
Suicide, Self Harm
An Adaptive Intervention for Adolescents at Risk for Suicide: A Pilot SMART
To inform the development of a technology-augmented adaptive intervention for adolescents at risk for suicide, the goal of this study is to conduct a Sequential, Multiple Assignment, Randomized Trial (SMART) pilot of a…
- Trial name
- NCT03838198
- Testing
- MI-Enhanced Safety Plan at Hospitalization (1st Component), MI-Enhanced Text Boosters (2nd Component), MI-Enhanced Booster Call (3rd Component)
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of Michigan
Schizophreniform Disorder, Schizoaffective Disorder
Open-label Ziprasidone Study for Psychosis Treatment in Adolescents
This open-label study will assess the medication Geodon® (Ziprasidone) in pediatric patients, aged 13-17, diagnosed with psychotic disorder.
- Conditions
- Schizophreniform Disorder, Schizoaffective Disorder, Psychosis, Depressive Disorder, Major
- Trial name
- NCT00421954
- Testing
- Ziprasidone
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- New York State Psychiatric Institute
Community-acquired Pneumonia, Acute Otitis Media
Using Electronically Derived Automated Reports of Appropriate Antibiotic Use to Inform Stewardship Interventions
The main goal of this study is to use automated electronic reports to assess and improve guideline-concordant antibiotic use for: 1) adult inpatients with community-acquired pneumonia; 2) pediatric inpatients with…
- Conditions
- Community-acquired Pneumonia, Acute Otitis Media, Pharyngitis
- Trial name
- EMPOWER (NCT06027593)
- Testing
- Quasi experimental intervention
- Where
- 2 sites in United States
- Volunteers
- 26,139 people
- Sponsor
- Children's Hospital of Philadelphia
Pain, Fever
Study of the Safety & Efficacy of Intravenous Acetaminophen in Pediatric Inpatients
Intravenous acetaminophen (IVAPAP) is safe in repeated dose, multi-day clinical use when administered at a daily dose of 40 to 75 mg/kg body weight
- Trial name
- NCT00598702
- Testing
- IV Acetaminophen
- Where
- 14 sites in United States
- Volunteers
- 100 people
- Sponsor
- Mallinckrodt
Chronic Respiratory Failure
Implementation of Nasal Non-Invasive Ventilation With a RAM Cannula in the Inpatient /Outpatient Setting
The purpose of this study is to implement a standardized protocol to initiate nasal non-invasive ventilation with RAM nasal cannula (NIV/RAM-NC) with Trilogy mechanical ventilator at Children Memorial Hospital inpatient and…
- Trial name
- NCT03473171
- Testing
- Nasal non-invasive ventilation with RAM cannula
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- The University of Texas Health Science Center, Houston
Anorexia Nervosa
Study of Refeeding to Optimize iNpatient Gains
The purpose of this study is to compare the efficacy, safety, and cost-effectiveness of lower calorie refeeding versus higher calorie refeeding in hospitalized adolescents with anorexia nervosa.
- Trial name
- StRONG (NCT02488109)
- Testing
- Higher Calorie Refeeding, Lower Calorie Refeeding
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of California, San Francisco
Pain, Fever
Safety and Pharmacokinetic (PK) Study of Intravenous (IV) Acetaminophen Administration in Pediatric Inpatients
We are doing this study to find out what happens to acetaminophen in the body after it is given to children through the vein. Children's bodies may handle drugs differently than adults.
- Trial name
- NCT00493246
- Testing
- IV Acetaminophen
- Where
- 5 sites in United States
- Volunteers
- 75 people
- Sponsor
- Mallinckrodt
Atypical Anorexia Nervosa
Individualized Study of Refeeding to Optimize iNpatient Gains
The primary purpose of the trial is to compare the efficacy and safety of Individualized Caloric Refeeding (ICR) to the new standard of care, Higher Calorie Refeeding (HCR), in hospitalized patients with atypical anorexia nervosa…
- Trial name
- i-STRONG (NCT04966858)
- Testing
- Individualized Caloric Refeeding (ICR), Higher Calorie Refeeding (HCR)
- Where
- 2 sites in United States
- Volunteers
- 77 people
- Sponsor
- University of California, San Francisco
Death, Pain
Intervention to Improve Care at Life's End
The BEACON trial (Best Practices for End-of-Life Care for Our Nations' Veterans) was a six-site implementation study to evaluate a multi-component, education-based intervention to improve the quality of end-of-life care provided…
- Conditions
- Death, Pain, Dyspnea
- Trial name
- BEACON (NCT00234286)
- Testing
- Comfort care education intervention
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- US Department of Veterans Affairs
Suicide, Attempted, Suicide and Depression
Ketamine Versus Midazolam for Recurrence of Suicidality in Adolescents
This project aims to examine the signal of efficacy of ketamine, a rapidly acting medication shown to decrease suicidality in adults in as short as hours or days, as opposed to weeks.
- Conditions
- Suicide, Attempted, Suicide and Depression, Suicide Threat
- Trial name
- TASK (NCT04592809)
- Testing
- Ketamine Hydrochloride, Midazolam Hydrochloride
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Texas Southwestern Medical Center
Vaping, Smoking
Adolescent Inpatient Tobacco and ENDS Intervention
The purpose of this study is to develop and evaluate an evidence-based intervention to assist adolescents and young adults with current vaping to quit vaping and smoking.
- Trial name
- NCT05936099
- Testing
- E-cigarette & Tobacco Use Treatment Intervention
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Very Low Birth Weight Infant
Fluid Balance Study in Sick Neonates
The purpose of this study is to determine if routinely recording fluid balance in sick neonates admitted to the pediatric ward is reliable and useful. The investigators' hypothesis is that it is not useful and reliable.
- Trial name
- NCT00962754
- Testing
- physician no insight in the fluid balance chart
- Where
- Netherlands
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Princess Amalia Children's Clinic
Suicidal Ideation, Suicide, Attempted
Establishing Efficacy of an Inpatient Intervention and Phone App to Reduce Suicidal Risk
In this 2-site study, University of Texas Southwestern Medical Center (UTSW) and Western Psychiatric Institute and Clinic (WPIC), the investigators will conduct a randomized clinical trial (RCT) in 240 psychiatrically…
- Trial name
- ASAP+BRITE (NCT03825588)
- Testing
- ASAP (As Safe As Possible), BRITE smart phone app, TAU (treatment as usual)
- Where
- 2 sites in United States
- Volunteers
- 241 people
- Sponsor
- University of Texas Southwestern Medical Center