Clinical trials: Intensive Care Unit
Development
Childhood Measures of NICU-based Chemical Exposure
This study aims to identify early life exposures to metals and chemicals by measuring the concentration of metals and organic compounds in shed primary teeth.
- Trial name
- NCT02292680
- Volunteers
- healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Critical Illness, Hyperglycemia
Tight Glycemic Control in Critical Care Patients
The purpose of this study is to evaluate the impact of tight control of serum glucose levels with an intensive insulin treatment in patients hospitalized in an intensive care unit with medical and surgical patients.
- Conditions
- Critical Illness, Hyperglycemia, Insulin Resistance
- Trial name
- NCT00096421
- Testing
- Tight control of blood glucose levels, Conventional control of glucose levels
- Where
- Colombia
- Volunteers
- 504 people
- Sponsor
- Hospital Pablo Tobón Uribe
Head Injuries With Non Missile Penetrating Objjects
Non-missile Penetrating Head Trauma,Cases Registry in Sohag University Hospital
A retrospective study was done in Neurosurgery trauma unit, Sohag University. Eighteen patients reported with different mechanisms of trauma. All patients clinically tested involving neurological evaluation.
- Trial name
- trauma (NCT03768778)
- Testing
- Debridement and dural repair
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Sohag University
Acute Kidney Injury
Predictors of Acute Kidney Injury in Critically Ill Children Admitted to PICU.
Predictors of Acute Kidney Injury in critically ill children admitted to PICU during one year.
- Trial name
- NCT06328478
- Testing
- Observational prospective study.
- Volunteers
- 100 people
- Sponsor
- Assiut University
Central Venous Catheter
Skin Decolonization of Children Hospitalized in Intensive Care Unit
The purpose of this study is to evaluate the efficacy and duration of the skin decolonization brought by a daily wash using Chlorhexidine Gluconate 2% pad compared to a standard wash with mild soap in children hospitalized in…
- Trial name
- DCpedrea (NCT04117776)
- Testing
- Skin microbiological sampling (wash with 2% Chlorhexidine Gluconate), Skin microbiological sampling (wash with mild soap)
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Respiratory Failure, Intensive Care Pediatric
The Effect of Music Therapy on Vital Signs and Heart Rate Variability of Pediatric Patients During the Extubation Process.
The extubation process is critical to the future health outcomes of the pediatric patient because it tests the ability of the respiratory system to function without the support of mechanical ventilation.
- Trial name
- NCT06591533
- Testing
- Music therapy + standard care, Standard Care (in control arm)
- Where
- 2 sites in Colombia
- Volunteers
- 82 people
- Sponsor
- Claudia Aristizábal
Multi-Drug Resistant Organisms, Late-Onset Sepsis, Neonatal
Using Antibiotics Wisely - An Antimicrobial Stewardship Program
There are significant variations in antimicrobial consumption across Canadian Neonatal Intensive Care Units (NICUs). Inappropriate and overuse of antibiotics can result in antimicrobial resistance and adverse outcomes among…
- Conditions
- Multi-Drug Resistant Organisms, Late-Onset Sepsis, Neonatal, Antimicrobial Resistance
- Trial name
- NCT04388293
- Testing
- Exposure of interest
- Where
- Canada
- Volunteers
- 2,000 people
- Sponsor
- University of British Columbia
Psychological Distress, COVID-19 Infection
Emotional Changes Between Emergency and Intensive Care Unit and On-site Counter Staffs After COVID-19 Infection
The emotional and work changes of the staffs and the on-site counter staffs will have a certain impact during this pandemic period.
- Conditions
- Psychological Distress, COVID-19 Infection, Anxiety and Fear-Related Disorders
- Trial name
- COVID-19 (NCT05908058)
- Testing
- Emotional Changes Investigation
- Where
- Taiwan
- Volunteers
- 52 people
- Sponsor
- St. Martin De Porress Hospital
Nosocomial Infection, Bacteremia
Skin Cleansing With Chlorhexidine to Decrease Hospital Acquired Infections
Patients in the intensive care unit are at risk for many infections because the severity of illness and the procedures necessary to care for them.
- Conditions
- Nosocomial Infection, Bacteremia, Sepsis, Pneumonia
- Trial name
- NCT00130221
- Testing
- 2% chlorhexidine gluconate impregnated cloth, Daily bathing with Bar soap
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- Cook County Health
Premature Baby 26 to 32 Weeks
Effects of Clustering Care on the Physiological Stability of Preterm Infants.
This crossover design experimental study aims to compare the physiological stability of premature newborns during and after a cluster of care compared to a period when they receive standard non clustered care at the neonatal unit.
- Trial name
- NCT03490721
- Testing
- Clustering care
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Université de Montréal
Pneumonia Childhood, Intensive Care Unit
Effect Of Cough Assist Device On Hemodynamic Status And Oxygen Saturation For Ventilated Children
Statement of the problem: •Is there an effect of the cough assist device on Hemodynamic status and oxygen saturation for ventilated children? Null hypothesis There will be no effect of cough assist device on hemodynamic status…
- Conditions
- Pneumonia Childhood, Intensive Care Unit, Children
- Trial name
- NCT06154876
- Testing
- Cough assist device
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Procedural Pain
Intranasal Fentanyl in Preterm Infants Undergoing Peripherally Inserted Central Catheter Placement
The purpose of this feasibility clinical trial is to explore the role of intranasal fentanyl for pain associated with PICC placement in preterm infants.
- Trial name
- INFENT PICC (NCT06590870)
- Testing
- Fentanyl, Normal saline
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Mount Sinai Hospital, Canada
Death Occurring in Intensive Care Units
Informed Consents for Withholding/Withdrawing Life Support in Intensive Care Units
End-of- life care is a major issue in medical ethics with life support technology progress. Intensive care may prolong the dying process in patients who have been unresponsive to the treatment already provided.
- Trial name
- NCT02020473
- Where
- South Korea
- Volunteers
- 348 people
- Sponsor
- Yonsei University
Weaning From Mechanical Ventilation in Care Unit
Prediction of the Spontaneous Breathing Test Success Using Biosignal and Biomarker in Critical Care Unit by a Machine Learning Approach
Context: Several authors have been interested in applying Artificial Intelligence (AI) to medicine, using various Machine Learning (ML) techniques: managing septic shock, predicting renal failure...
- Trial name
- NCT05886803
- Testing
- Spontaneous ventilation test
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Critical Illness, Pediatric Intensive Care
Continuous vs Bolus Protein (Protein Regimen Outcomes) in Critically Ill Children (Kids In Distress)
The goal of this intervention study is to evaluate the difference in nutrition status markers (weight and muscle mass) when giving dietary protein by continuous or bolus delivery in critically ill children ages 1-11y.
- Conditions
- Critical Illness, Pediatric Intensive Care, Enteral Nutrition Therapy, Dietary Protein
- Trial name
- PRO-KID (NCT06721923)
- Testing
- Dietary protein
- Where
- Canada
- Volunteers
- 96 people
- Sponsor
- University of British Columbia
Coronavirus, Post Intensive Care Unit Syndrome
The Usability, Feasibility, and Tolerability of Virtual Reality for Rehabilitation From COVID-19
Patients who receive intensive care are known to be at high risk for physical, psychological, and cognitive impairments, a constellation known as PICS.
- Trial name
- COVRehab (NCT04505761)
- Testing
- Virtual Reality
- Where
- Netherlands
- Volunteers
- 48 people
- Sponsor
- Radboud University Medical Center
Diabetes Mellitus, Covid19
Clinical Phenotype and Outcomes of Inpatients With COVID-19 and Diabetes
Patients with diabetes have been listed as people at higher risk for severe illness from COVID-19. Moreover, the relationship between diabetes-related phenotypes and the severity of COVID-19 remains unknown.
- Trial name
- NCT04550403
- Where
- Italy
- Volunteers
- 757 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Pneumonia
Anaerobic Antibiotic Usage for Pneumonia in the Medical Intensive Care Unit
Observation of prescription usage of anaerobic antibiotics for patients admitted to the ICU with pneumonia.
- Trial name
- NCT03046082
- Testing
- Antibiotics
- Volunteers
- 192 people
- Sponsor
- Henry Ford Health System
Asthma (Diagnosis)
Pediatric Asthma Trial of Corticosteroid Heterogeneity (PATCH): Trial of Dexamethasone Versus Methylprednisolone for Pediatric Critical Asthma
Acute asthma exacerbation is caused by dysregulated pulmonary inflammatory pathways such that standard treatment includes prompt administration of exogenous systemic corticosteroids (SCs), but there remains an ongoing dialogue…
- Trial name
- PATCH (NCT07455396)
- Testing
- Dexamethasone (0.6mg/kg; Max 16mg) Once Daily, Dexamethasone (0.25 mg/kg/dose, Max dose 16mg) every 6-hours, Methylprednisolone
- Where
- United States
- Volunteers
- 159 people
- Sponsor
- Johns Hopkins All Children's Hospital
Intensive Care
Charge Transparency in Critical Care Practice and Its Effects on Overall Cost of Care
To investigate the effects of the availability of daily patient-related charges on ordering patterns of health care ordering providers and cost containment in the Intensive Care Unit (ICU) setting.
- Trial name
- PRICE (NCT02476591)
- Testing
- Charge Transparency
- Volunteers
- 10,720 people
- Sponsor
- Vanderbilt University