Clinical trials: Interaction
Autism Spectrum Disorder
Effectiveness Trial of Mobile ESI for Toddlers With Autism Identified by Early Screening in Primary Care
The goal of this collaborative R01 is to demonstrate the therapeutic value and community-wide implementability of an early intervention (EI) platform for toddlers with autism spectrum disorder (ASD) that is completely virtual…
- Trial name
- ESI-MC (NCT05456139)
- Testing
- Treatment as Usual, Early Social Interaction Mobile Coaching (ESI-MC)
- Where
- 8 sites in United States
- Volunteers
- 52 people
- Sponsor
- Florida State University
Anxiety, Trauma
Animal Assisted Therapy
This study looks at whether walking with a therapy dog helps adult and pediatric trauma patients move more during their hospital stay.
- Conditions
- Anxiety, Trauma, Hospitalized Adult Patients, Rehabilitation
- Trial name
- NCT07227181
- Testing
- Therapy Dog, Standard mobilization
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Andrew Bernard
Dentofacial Deformities, Sleep Disorder
Interaction Between Body Posture and Nocturnal Sleeping Disorders in Dysgnathic Patients
The role of head posture has been demonstrated in patient with dentofacial deformities. However, the relationship between body posture and jaw disorders is unclear.
- Conditions
- Dentofacial Deformities, Sleep Disorder, Posture
- Trial name
- NCT03532828
- Testing
- polysomnography
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Laboratoire de Biomécanique Georges Charpak
Type 1 Diabetes
Gene-virus Interactions Implicated in Type 1 Diabetes
Type 1 diabetes (T1D) is the most common endocrine disorder in children. In France, T1D prevalence is estimated to 12.2 per 100 000. Worldwide T1D incidence increased rapidly in the last decades, around 3% per year.
- Trial name
- GENEVIR (NCT02804165)
- Testing
- Enterovirus vaccination
- Where
- France
- Sponsor
- Hospices Civils de Lyon
Vaccine Preventable Disease, Measles
Measles and BCG Vaccines for Mother and Child
In Africa, the mortality from infectious diseases remains high. The investigators have discovered that live vaccines such as the BCG vaccine against tuberculosis and the measles vaccine can strengthen resistance to other…
- Conditions
- Vaccine Preventable Disease, Measles, Mother-Infant Interaction, BCG Vaccination Reaction
- Trial name
- MATVAC (NCT04899765)
- Testing
- BCG vaccine, Measles vaccine
- Where
- Guinea-Bissau
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Bandim Health Project
Premature Birth
A Longitudinal Study of Effectiveness of Early Intervention for Preterm Infants
The main purpose of this study is to extend the investigators' previous research to longitudinally examine the effectiveness of three early intervention programs: usual care program, clinic-based intervention program and…
- Trial name
- NCT00946244
- Where
- Taiwan
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Rhinovirus
Impact of Covid-19 on Rhinovirus Epidemic
Rhinovirus (RV) has long been known as the main etiological agent of "common colds" among children and adults. Indeed, RV is involved in more than 50% of upper respiratory tract infections (URTIs), mostly characterized by nasal…
- Trial name
- IPCoRV (NCT05348707)
- Testing
- epidemiology
- Volunteers
- 400 people
- Sponsor
- Hospices Civils de Lyon
Immunization; Infection, SMS
Use of SMS and Interactive Reminders to Improve Timely Immunization Coverage
Pakistan has one of the highest infant mortality rates in the world. One child in eleven dies before their fifth birthday. In part, this is due to the low coverage rate of routine childhood immunizations.
- Trial name
- NCT03379467
- Testing
- SMS Reminder, Interactive Reminder
- Volunteers
- 655 people, healthy volunteers welcome
- Sponsor
- Interactive Research and Development
Spinal Cord Injury, Stroke
Interactive Motor Imagery in Virtual Reality
This project will build and test the first rehabilitation system employing virtual reality (VR)-based observation, motor imagery and execution to treat lower-limb neuropathic pain and motor dysfunction in participants with an…
- Trial name
- NCT02149186
- Testing
- iCTuS-L
- Where
- Switzerland
- Volunteers
- 79 people
- Sponsor
- University of Zurich
PreTerm Birth, Stress Reaction
The Contribution of Parent-infant Interaction While Singing During Kangaroo Care, on Preterm-infants' Autonomic Stability and Parental Anxiety Reduction
The current study will investigate the combination of the two modalities in a mixed-methods design, in order to provide comprehensive knowledge regarding the effects of family-centered MT during KC, on premature-infants'…
- Trial name
- NCT03023267
- Testing
- Music therapy and Kangaroo care, Kangaroo Care alone
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Meir Medical Center
Medical Education, Clinical Communication
Adaptive Real-Time Voice Virtual Patients for Clinical Communication Training
This study evaluated whether an emotionally and interactionally adaptive real-time voice virtual patient can improve clinical communication training for resident physicians.
- Conditions
- Medical Education, Clinical Communication, Breaking Bad News Skills
- Trial name
- RSTM-VP (NCT07615621)
- Testing
- Adaptive Real-Time Voice Virtual Patient Training, Non-Adaptive Real-Time Voice Virtual Patient Training, Standardized Patient Training
- Where
- China
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Wang Shalong
Artificial Intelligence (AI) in Diagnosis, Decision Making
Training Diagnostic Specialists to Use Artificial Intelligence Safely: The DISCORD-Dx Study
This randomized study evaluated whether a structured reasoning strategy called DISCORD-Dx could help specialist doctors use artificial intelligence (AI) recommendations more safely during diagnostic decision-making.
- Trial name
- DISCORD-Dx (NCT07844889)
- Testing
- DISCORD-Dx Training, Conventional AI-Literacy Training
- Where
- Pakistan
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Sara Reza
Preterm, Preterm Infant Development
Nutritional Maturity in Preterm Newborns (Premature Infant Oral Motor Intervention, PIOMI)
Premature Infant Oral Motor Intervention (PIOMI) has been found to improve short-term clinical outcomes in preterm infants and contribute to their feeding skills.
- Trial name
- PIOMI (NCT07894380)
- Testing
- The PIOMI initiative in maternal interaction, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Animal-Human Bonding, Animal-assisted Intervention
Benefits of Judicial Assistance Dogs for Child Victims in Child Advocacy and Pediatric Assessment Units (UAPEDs)
Child maltreatment is common and encompasses various forms, including psychological, physical, and sexual abuse, exposure to domestic violence, neglect, and sexual exploitation.
- Conditions
- Animal-Human Bonding, Animal-assisted Intervention, Behavioural Responses to Contact With Dogs
- Trial name
- AudiCAJ (NCT07811479)
- Testing
- Judicial Assistance Dog
- Where
- France
- Volunteers
- 46 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
HIV Infections, Sexual Behavior
Keeping it LITE: Exploring HIV Risk in Vulnerable Youth With Limited Interaction and Digital Health Intervention
Despite advances in HIV diagnostics, care and prevention strategies, infection rates among adolescent and young adult sexual and gender minorities (SGM) continue to rise in the United States (US).
- Trial name
- LITE-2 (NCT05848570)
- Testing
- Keeping it LITE
- Where
- United States
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Hektoen Institute for Medical Research
Attention-Deficit Hyperactivity Disorder, Unspecified Type, Autism Spectrum Disorder
A Multi-dimensional Prospective Study to Discover Gene-microenvironment Interactions in Neurodevelopmental Disorders
This project is the first involving the two most common neurodevelopmental disorders, ASD and ADHD, as well as TDC to establish a multi-dimensional database (clinic, behavior, neurocognitive function, brain imaging, metabolomics…
- Trial name
- NCT04878575
- Testing
- ASD diagnosis, Psychiatric diagnosis
- Where
- Taiwan
- Volunteers
- 360 people
- Sponsor
- National Taiwan University Hospital
Obesity and Overweight, Leptin Resistance
Reprogramming Energy Homeostasis in Overweight Individuals Via Exercise, Cognitive, and Social Training
The RESILIENT project is a clinical trial investigating leptin sensitivity in both children and adults with overweight or obesity.
- Conditions
- Obesity and Overweight, Leptin Resistance, Childhood Obesity
- Trial name
- Resilient (NCT06931730)
- Testing
- Nutritional Intervention, Physical Activity training, Cognitive training
- Where
- 2 sites in Italy
- Volunteers
- 240 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Dyslexia, Developmental, Language Development Disorders
Language Development Deficits and Early Interactive Music Intervention
Investigators compare effects of 6-month music versus circus group interventions on language development in infants and toddlers with or without familial risk for dyslexia (anticipated total N=200).
- Conditions
- Dyslexia, Developmental, Language Development Disorders, Language Development
- Trial name
- BusyBaby (NCT06261307)
- Testing
- Music intervention, Circus intervention
- Where
- Finland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Anxiety
Interactive Tablet Compared to Oral Midazolam as Premedication in Preoperative Anxiety in Children
preoperative anxiety is an undesirable outcome in pediatric surgical patients.It can lead to behavioral trouble such as enuresis, apathy and sleep disorders.
- Trial name
- NCT04049201
- Testing
- elective surgery, Midazolam, Interactive Tablet
- Where
- Tunisia
- Volunteers
- 112 people
- Sponsor
- Hôpital d'enfants Béchir-Hamza
Healthy
Cranberry Flavan-3-ols Consumption and Gut Microbiota in Healthy Adults
Consumption of (poly)phenols is recognized to have beneficial effects on health. However, heterogeneous results are obtained in clinical trials due to high inter-individual variability.
- Trial name
- NCT05931237
- Testing
- Cranberry extract capsules
- Where
- Canada
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Laval University