Clinical trials: Interventional Study
Type 1 Diabetes
EMPoWER Study - Strengths-based Behavioral Intervention for Youth With Type 1 Diabetes
The EMPoWER Study randomized clinical trial is a strengths-based behavioral intervention delivered to youth with type 1 diabetes (age 10 to 13) and their parents.
- Trial name
- EMPoWER (NCT06014879)
- Testing
- Type 1 Doing Well (T1DW) Program, Diabetes-Related Information and Resources Program
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Baylor College of Medicine
Diabetes
Diabetes Management Personal Trainer
This 1-year study will test the feasibility and effectiveness of a diabetes personal trainer in helping youth with diabetes manage their treatment.
- Trial name
- NCT00340093
- Testing
- Managing Diabetes
- Where
- 2 sites in United States
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Postpartum Depression (PPD)
Salutogenesis and Self-efficacy-based Childbirth Education Programme for Preventing Postpartum Depression
Although the transition to motherhood is often a joyful experience, there is evidence that teenage motherhood can present many stressful challenges, potentially leading to the development of postpartum depression.
- Trial name
- NCT06698107
- Testing
- Childbirth education programme, Usual Care
- Where
- 4 sites in Ethiopia
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Celiac Disease
Risk of Celiac Disease and Age at Gluten Introduction
The purpose of this study is to determine whether age at introduction of gluten-containing cereals (e.g. wheat) plays a role in influencing the risk of celiac disease (CD) development in infants with a first-degree relative…
- Trial name
- CELIPREV (NCT00639444)
- Testing
- gluten-free, normocaloric diet from 6 to 12 months
- Where
- Italy
- Volunteers
- 703 people
- Sponsor
- Università Politecnica delle Marche
Asthma
Investigation of the Role of Pictorial Asthma Action Plans to Promote Self-management in Rural Youth With Asthma
The aim of this study is to investigate the potential benefit of Pictorial versus Written Asthma Action Plans (AAPs) to support asthma management among young people with persistent asthma.
- Trial name
- TAAC (NCT03187119)
- Testing
- Pictorial Asthma Action Plan, Written Asthma Action Plan
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- West Virginia University
Fruit and Vegetable Intake
Effects of a Smartphone Application on Fruit and Vegetable Consumption Among Saudi Adolescents
Background: Dietary patterns and nutritional status during adolescence have a direct effect on future health outcomes. Objective: This study aimed to promote fruit and vegetable intake among adolescents using a smartphone…
- Trial name
- F&V intake (NCT05692765)
- Testing
- smartphone application to enhance fruit and vegetables intake among adolescents
- Where
- Saudi Arabia
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Tinea Pedis
Topical Tolnaftate Stick for Tinea Pedis: An Open-Label Interventional Study
This study is designed to evaluate the safety and effectiveness of multiple 1% tolnaftate formulations delivered through novel stick-based vehicles in individuals with tinea pedis (athlete's foot).
- Trial name
- NCT07245667
- Testing
- 1% Tolnaftate Stick Formula A, 1% Tolnaftate Stick Formula B, 1% Tolnaftate Stick Formula C
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Propedix, Inc.
Symptomatic Knee Osteoarthritis
Micro-fragmented Adipose Tissue Injection Associated With Arthroscopic Procedures in Patients With Knee Osteoarthritis
The study aims to evaluate the effects of a single intra-articular injection of micro-fragmented adipose tissue obtained with the Lipogems® system in patients affected by knee chondropathy.
- Trial name
- LOOK (NCT03527693)
- Testing
- Lipogems injection
- Volunteers
- 38 people
- Sponsor
- Spotorno Foundation
Lennox-Gastaut Syndrome
Cannabidiol Oral Solution as an Adjunctive Therapy for Treatment of Participants With Inadequately Controlled Lennox-Gastaut Syndrome
This Phase 3 trial will enroll participants diagnosed with Lennox-Gastaut Syndrome (LGS) who are still experiencing at least 4 motor seizures involving the trunk or extremities per week, despite ongoing treatment with up to 3…
- Trial name
- NCT02318537
- Testing
- Cannabidiol Oral Solution
- Sponsor
- INSYS Therapeutics Inc
Children, Obesity & Overweight
A Multifaceted Intervention to Reduce Obesity Among Preschool Children: Study Protocol for a Randomized Controlled Trial in Suzhou City
This study aimed to develop a comprehensive, multi-faceted intervention program for weight control and systematically evaluated its effectiveness on indicators of adiposity.
- Conditions
- Children, Obesity & Overweight, Intervention
- Trial name
- NCT07361211
- Testing
- Student-focused activities, Activities towards parents (providing a supportive family environment), Activities towards schools (providing a supportive school environment)
- Where
- China
- Volunteers
- 1,486 people, healthy volunteers welcome
- Sponsor
- Soochow University
Work-Related Stress, Coping Behaviour
Qualitative Exploration of a Mobile Stress Management Intervention for Mental Health Workers
The goal of this qualitative intervention study is to explore the experiences of mental healthcare workers using the STAPP@Work app to manage work-related stress.
- Conditions
- Work-Related Stress, Coping Behaviour, User Experience of Mobile Application
- Trial name
- NCT06991439
- Testing
- A self-monitoring mobile application for stress management at work
- Where
- Netherlands
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Sevda Demirel
COPD
Non-interventional Study of Spirometry Use to Diagnose COPD (Chronic Obstructive Pulmonary Disease) and to Prescribe Treatment to COPD Patients in the Outpatient Institutions
This study is an observational multicenter descriptive study. The study will be conducted in primary outpatient medical institutions in different cities of the RF.
- Trial name
- SUPPORT (NCT02248909)
- Where
- 22 sites in Russia
- Volunteers
- 4,232 people
- Sponsor
- AstraZeneca
Domestic Violence
Nurse-family Partnership (NFP) Curriculum Study
The purpose of this study is to determine whether the Intimate Partner Violence (IPV) intervention in the context of Nurse-Family Partnership (NFP) program improves women's quality of life and reduces violence relative to the NFP…
- Trial name
- NCT01372098
- Testing
- NFP + IPV intervention
- Where
- United States
- Volunteers
- 492 people
- Sponsor
- McMaster University
Adolescent Obesity
TRUST Study of Adolescent Weight Self-Management
The purpose of this pilot study is to evaluate the effect of the Trust-building weight Self-management Together (TRUST) intervention on weight self-management behaviors and neural processing in overweight/obese adolescents.
- Trial name
- TRUST (NCT03016247)
- Testing
- TRUST Intervention, Enhanced Usual Care
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
HIV, Adolescent Behavior
Gender-Specific Combination HIV Prevention for Youth in High Burden Settings (MP3-Youth)
MP3 Youth is a pilot study to evaluate the feasibility and acceptability of a gender-specific combination HIV prevention package for youth (aged 15-24) in high burden settings.
- Conditions
- HIV, Adolescent Behavior, Gender
- Trial name
- MP3-Youth (NCT01571128)
- Testing
- Male-Specific Intervention Package, Female-Specific Intervention Package, Pre-Exposure Prophylaxis (Females)
- Where
- 3 sites in United States, Kenya
- Volunteers
- 1,215 people, healthy volunteers welcome
- Sponsor
- New York University
Pain
The Benefit of the Intervention of Clowns in Pediatric Oncology in the Accompaniment of Painful Acts
The diagnosis and treatment of childhood cancer involves frequent and repeated painful acts. The pediatric oncology-hematology service of Nancy's hospital innovates thanks to the involvement of clowns in the hospital.
- Trial name
- ICOD (NCT05206344)
- Testing
- clowns
- Where
- France
- Volunteers
- 74 people
- Sponsor
- Central Hospital, Nancy, France
Health Behavior, Adolescence
THRIVE-Belize: A School-Based Life-Skills Program to Support Teen Health in Toledo District, Belize (Feasibility)
THRIVE-Belize is a school-based program being developed to support the health and well-being of adolescents in the Toledo District of southern Belize.
- Conditions
- Health Behavior, Adolescence, Feasibility Studies
- Trial name
- THRIVE-Belize (NCT07687199)
- Where
- Belize
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Sleep Apnea, Obstructive, Motivational Interviewing
The MotivAir Study to Improve CPAP Adherence in OSAS Patients
This study aims to evaluate the effectiveness of the MotivAir program an intervention based on Motivational Interviewing (MI) principles and techniques - in enhancing adherence to Continuous Positive Airway Pressure (CPAP)…
- Trial name
- MotivAir (NCT05767190)
- Testing
- Motivational interviewing
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Istituto Auxologico Italiano
Anaemia
Triple Outcome Evaluation of Red Teff Intervention for Infant Anemia, Environmental Health, and Economic Feasibility in Ethiopia: A Self-controlled Pre-post Study
Background. Childhood anemia affects more than 40% of under-five children in Ethiopia, where iron supplementation has achieved limited success and locally grounded, sustainable strategies are needed.
- Trial name
- NCT07912697
- Testing
- Red teff (Eragrostis teff) porridge
- Where
- Ethiopia
- Volunteers
- 32 people
- Sponsor
- Debre Markos University
Premature Infants, Very Low Birth Weight Infants
The Video System to Provide a Developmental Training Guide for Preterm Infants
This study aimed to establish a systematic developmental training guide protocol for parent-centered early intervention and verify the concept and feasibility of a video system for parent-centered in-home developmental therapy…
- Trial name
- NCT06965842
- Testing
- Parent-centered developmental training
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Seoul National University Hospital
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