Clinical trials: Intestinal Infection
Ruptured Appendicitis
Early Versus Interval Appendectomy for Ruptured Appendicitis in Children
The purpose of this randomized trial is to compare two commonly utilized surgical treatments for children with ruptured appendicitis: early appendectomy, versus interval appendectomy.
- Trial name
- RAPTOR (NCT00435032)
- Testing
- early appendectomy, interval appendectomy
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Tennessee
Healthy
Environmental Game After Appendicitis Surgery
This study was conducted to determine the effect of environmental play and mobilization on fear and pain levels of children aged 6-12 years who had acute appendicitis surgery.
- Trial name
- NCT05104021
- Testing
- game
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Okan University
Late Onset Neonatal Sepsis, Necrotizing Enterocolitis
Effects of Oral Probiotic Supplementation on the Clinical Status of Very-low-birth-weight Preterm Neonates.
The purpose of this study was to evaluate the safety of a probiotic foodstuff and its influence on emergence and development of natural intestinal flora and the clinical status of premature very low birth weight neonates.
- Conditions
- Late Onset Neonatal Sepsis, Necrotizing Enterocolitis, Infant, Very Low Birth Weight
- Trial name
- NCT02073214
- Testing
- Probiotic
- Volunteers
- 182 people
- Sponsor
- IBSS Biomed S.A.
Acute Appendicitis
Sensitivity and Specificity of the Alvarado Score for the Timely Differential Diagnosis of Acute Appendicitis in Samoa
Retrospective clinical data review design of all patients admitted to the Tupua Tamasese Meaole Hospital Surgical Unit for AA from January 2015 to December 2016.
- Trial name
- NCT05168410
- Testing
- Alvarado Score
- Volunteers
- 225 people
- Sponsor
- Dr Annette Kaspar
Diarrhoea, Soil-transmitted Helminth Infection
Cluster Randomised Trial of Improved Sanitation in Rural Orissa, India
The study is a cluster-randomized, controlled trial conducted among 100 villages (including approximately 3500 households and 20,000 people) in Puri district, State of Orissa, India.
- Conditions
- Diarrhoea, Soil-transmitted Helminth Infection, Nutritional Status
- Trial name
- NCT01214785
- Testing
- Provision of household latrines
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Helminthiasis, Diarrhea
Spillover Effects of Water, Sanitation, and Hygiene Interventions on Child Health
The purpose of this study is to measure whether a combined water, sanitation, and hygiene intervention leads to improved health of children who did not receive the intervention themselves and who live within a close vicinity of…
- Conditions
- Helminthiasis, Diarrhea, Respiratory Infection
- Trial name
- NCT02396407
- Testing
- Combined water, sanitation, and hygiene
- Where
- Bangladesh
- Volunteers
- 1,789 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Acute Appendicitis
Perioperative Hyperoxygenation and Wound Site Infection Following Surgery for Acute Appendicitis
Patients undergoing open appendectomy for acute appendicitis were enrolled in a randomized prospective study.
- Trial name
- NCT01002365
- Testing
- Oxygen delivery, Oxygen administration
- Where
- Israel
- Sponsor
- Western Galilee Hospital-Nahariya
Acute Pain, Abdominal Pain
Comparison of Ketorolac at Three Doses in Children With Acute Pain
Hospital Scene #1: A 6-year-old arrives in the Emergency Department at McMaster Children's Hospital (MCH) complaining of pain in his lower right side.
- Conditions
- Acute Pain, Abdominal Pain, Migraine, Appendicitis Acute
- Trial name
- KETODOSE (NCT05641363)
- Testing
- Ketorolac Tromethamine
- Where
- 2 sites in Canada
- Volunteers
- 171 people
- Sponsor
- Hamilton Health Sciences Corporation
Perforated Appendicitis
The Effect of Gum Chewing on Postoperative Ileus
The purpose of this study is to see if chewing gum after surgery for perforated appendicitis will shorten the time of intestinal dysfunction.
- Trial name
- NCT00879294
- Testing
- Motion sickness wristband, Chewing Gum
- Where
- United States
- Sponsor
- Wake Forest University
Appendicitis
Antimicrobial Stewardship in Pediatric Surgery
Acute appendicitis is a common surgical emergency in children. Non-perforated appendicitis patients do not require antibiotics after appendectomy.
- Trial name
- AbxPS (NCT02270996)
- Testing
- Antimicrobial Stewardship Program
- Volunteers
- healthy volunteers welcome
- Sponsor
- Alberta Children's Hospital
Perforated Appendicitis
Initial Versus Delayed Operation for Treatment of Complicated Appendicitis In Children
To determine the most cost effective way to treat children with perforated appendicitis we will randomize all children presenting with perforated appendicitis to initial operation, with in 24 hours of admission, or to initial…
- Trial name
- NCT00540189
- Testing
- Initial appendectomy, Interval appendectomy
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Michigan
Appendicitis, Child
CT Scan Using IV Contrast Alone for Pediatric Appendicitis
Computed tomography (CT) scan using intravenous contrast (CT IV) as the sole type of contrast material, was studied as one method of evaluating children with suspected appendicitis.
- Conditions
- Appendicitis, Child, Contrast Media
- Trial name
- NCT00716703
- Testing
- CT Scan using IV contrast alone
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Rochester
Acute Myeloid Leukemia/Transient Myeloproliferative Disorder, Acute Undifferentiated Leukemia
Fludarabine Phosphate and Total-Body Radiation Followed by Donor Peripheral Blood Stem Cell Transplant and Immunosuppression in Treating Patients With Hematologic Malignancies
This clinical trial studies fludarabine phosphate and total-body radiation followed by donor peripheral blood stem cell transplant and immunosuppression in treating patients with hematologic malignancies.
- Conditions
- Acute Myeloid Leukemia/Transient Myeloproliferative Disorder, Acute Undifferentiated Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission
- Trial name
- NCT00014235
- Testing
- fludarabine phosphate, total-body irradiation, peripheral blood stem cell transplantation
- Where
- 11 sites in United States, Germany and 1 more
- Volunteers
- 160 people
- Sponsor
- Fred Hutchinson Cancer Center
Microbial Colonization
Comparing Impacts of Donor Human Milk to Formula Supplementation on the Gut Microbiome of Full-term Infants
The goal of this pilot randomized controlled trial (RCT) is to examine donor human milk (DHM) as a clinical intervention targeted at achieving beneficial microbiome signatures in full-term infants who are exposed to intrapartum…
- Trial name
- PPDHM (NCT05815433)
- Testing
- Donor Human Milk - Nutritional Replacement
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Anemia, Iron Deficiency
Iron and Prebiotics Fortification in Kenyan Infants
Iron deficiency and anemia are health issues affecting mainly infants and women in developing countries. Iron deficiency in infancy can have long-lasting impact on cognitive and motor development of the child.
- Conditions
- Anemia, Iron Deficiency, Diarrhea, Malaria
- Trial name
- Iro'n'Pre (NCT02118402)
- Testing
- Fortified maize porridge
- Where
- Kenya
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Pediatric Hernia, Laparoscopic Surgery
Ciprofol Based on Total Intravenous Anesthesia During Pediatric Laparoscopic Surgery
a prospective, double-blind, fully randomized controlled, non-inferiority clinical trial to investigate the use of total intravenous anesthesia in pediatric laparoscopic surgery.
- Conditions
- Pediatric Hernia, Laparoscopic Surgery, Appendicitis, Surgery
- Trial name
- NCT06735430
- Testing
- Ciprofol, Propofol
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Tongji Hospital
Chronic Hepatitis B Infection, Healthy
Study on Gut Microbiota in Chronic HBV Infected Patients
Hepatitis B Virus(HBV) infection is a common infectious disease affecting up to 2 billion people worldwide. Around 650 thousand people died of liver failure, cirrhosis and primary liver cancer caused by chronic hepatitis B every…
- Trial name
- HBV (NCT03587467)
- Testing
- collect fecal specimens
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zhongshan Hospital Xiamen University
COVID-19 Complicated With Refractory Intestinal Infections
Washed Microbiota Transplantation for Patients With 2019-nCoV Infection
Gut dysbiosis co-exists in patients with coronavirus pneumonia. Some of these patients would develop secondary bacterial infections and antibiotic-associated diarrhea (AAD).
- Trial name
- NCT04251767
- Testing
- washed microbiota transplantation
- Where
- China
- Sponsor
- The Second Hospital of Nanjing Medical University
Diarrhea
Etiology of Diarrhea in Guinea-Bissau and in Finland
Diarrhoea is the leading cause of death in the world with 2.2 million deaths every year. The majority of deaths are among children in developing countries, but the travellers encounter the disease as well.
- Trial name
- NCT01269554
- Where
- 3 sites in Finland, Guinea-Bissau
- Volunteers
- 920 people, healthy volunteers welcome
- Sponsor
- Bandim Health Project
Appendicitis
Transversus Abdominis Plane (TAP) Versus Local Anesthetic for Lap Appendectomies
This study is a prospective, double-blinded, randomized comparison of 2 patient cohorts. One group of patients will receive a transversus abdominis plane (TAP) block.
- Trial name
- NCT01575028
- Testing
- Ropivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Nationwide Children's Hospital