Clinical trials: Intestinal Infection
Uncomplicated Acute Appendicitis
Clinical Pathway With "Fast-Track" In Uncomplicated Acute Appendicitis
The aim of this study is to reduce the postoperative hospital stay, without increasing morbidity and mortality postoperative, expressed in terms of rate of complications and readmissions.
- Trial name
- CLIPUA (NCT02326415)
- Testing
- Clinical Pathway with "Fast-Track", Postoperative Usual Protocol
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Hospital Universitario Virgen de la Arrixaca
Diarrhea, Diarrhea Infectious
A Baseline Study in Support of Clinical Evaluation of an Oral Shigella Vaccine Development in Africa
This study aims to address the paucity of accurate incidence data of diarrheal diseases associated with Shigella in Zambia and Burkina Faso.
- Trial name
- ShigOraVax (NCT04312906)
- Testing
- no intervention
- Where
- 3 sites in Burkina Faso, Zambia
- Volunteers
- 1,334 people, healthy volunteers welcome
- Sponsor
- Centre for Infectious Disease Research in Zambia
Blood Stream Infection, Gut Microbiota
Application of Nanopore Sequencing in Newly Diagnosed Acute Myeloid Leukemia Patients With Bloodstream Infection
Acute myeloid leukemia (AML) patients are prone to blood stream infection (BSI) due to bone marrow suppression, oral and gastrointestinal mucositis, endovascular tubes, and the application of a large number of broad-spectrum…
- Conditions
- Blood Stream Infection, Gut Microbiota, Acute Myeloid Leukemia
- Trial name
- NCT05016752
- Where
- China
- Volunteers
- 20 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Pain, Postoperative, Appendicitis
Choose the Best Concentration of Ropivacaine on TAP Block for Open Appendectomy in Children
Blockage of the transverse abdomen (TAP) promotes excellent analgesia of the abdominal wall and the parietal peritoneum. The TAP block could advange the postoperative pain of Appendectomy in children.
- Trial name
- NCT03005808
- Testing
- Ropivacaine
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital Infantil Albert Sabin
Appendicitis
Nebulized Analgesia for Laparoscopic Appendectomy Trial
The objective of this study is to assess whether the administration of nebulized intra-peritoneal ropivacaine at the onset of surgery, compared with nebulized saline, reduces morphine consumption after laparoscopic appendectomy…
- Trial name
- NALA (NCT02624089)
- Testing
- Ropivacaine, Normal saline
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Acute Myeloid Leukemia/Transient Myeloproliferative Disorder, Acute Undifferentiated Leukemia
Fludarabine Phosphate and Total-Body Radiation Followed by Donor Peripheral Blood Stem Cell Transplant and Immunosuppression in Treating Patients With Hematologic Malignancies
This clinical trial studies fludarabine phosphate and total-body radiation followed by donor peripheral blood stem cell transplant and immunosuppression in treating patients with hematologic malignancies.
- Conditions
- Acute Myeloid Leukemia/Transient Myeloproliferative Disorder, Acute Undifferentiated Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission
- Trial name
- NCT00014235
- Testing
- fludarabine phosphate, total-body irradiation, peripheral blood stem cell transplantation
- Where
- 11 sites in United States, Germany and 1 more
- Volunteers
- 160 people
- Sponsor
- Fred Hutchinson Cancer Center
Acute Bronchitis
The Sublimated Mare Milk Supplement's Effect on Gut Mucosal Lining After Antibiotics
This clinical trial studies the effect of sublimated mare milk supplement on gut microbiome of patients with acute bronchitis.
- Trial name
- NCT03657836
- Testing
- Sublimated mare milk supplement, Standard antibiotic therapy
- Where
- Kazakhstan
- Volunteers
- 12 people
- Sponsor
- Nazarbayev University Medical Center
Appendicitis, Appendicitis; Perforation
Probiotics and Antibiotic Associated Diarrhea in Pediatric Complicated Appendicitis
To determine the effectiveness of the use of probiotics in patients with a diagnosis of complicated appendicitis on antibiotic associated diarrhea (AAD).
- Trial name
- NCT04529980
- Testing
- Lactobacillus rhamnosus GG (LGG) Probiotic
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Children's Health
Gastro-intestinal Infections, Infections With Fever
Effect of Starter Formula on Infection Prevention
The aim of this trial is to test the efficacy of an infant formula containing synbiotics on the prevention of gastro-intestinal infections.
- Trial name
- NCT01880970
- Testing
- starter infant formula with pro and prebiotics
- Where
- 7 sites in France, Germany and 1 more
- Volunteers
- 477 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Schistosomiasis
Evaluation of Strategies for Improved Uptake of Preventive Treatment for Intestinal Schistosomiasis
Previous research undertaken among adults in high endemic districts of Busia, Adjumani, Moyo and Nebbi reported unwillingness to take preventive treatment.
- Trial name
- ESIUPT (NCT01869465)
- Testing
- Pre-treatment snack, Education arm
- Where
- Uganda
- Volunteers
- 1,277 people
- Sponsor
- Makerere University
Appendicitis Acute
Value of Ultrasound and Computed Tomography in the Diagnosis of Acute Appendicitis With Histopathology as Gold Standard.
This study is a retrospective evaluation of all patients treated surgically for appendicitis over a period of 3 years at the Sint- Andries Hospital, Tielt. Belgium.
- Trial name
- NCT05070000
- Testing
- Radiologic examination
- Volunteers
- 304 people
- Sponsor
- KU Leuven
SEPSIS, MALNUTRITION, CHILD
Pancreatic Enzymes and Bile Acids in Acutely Ill Severely Malnourished Children
Children with severe malnutrition who are sick and admitted to hospitals have high mortality, usually because of infection. Malnourished children have more potentially harmful bacteria in their upper intestines than…
- Trial name
- PB-SAM (NCT04542473)
- Testing
- Pancreatic Enzyme, Ursodeoxycholic acid
- Where
- 4 sites in Bangladesh, Kenya and 2 more
- Volunteers
- 400 people
- Sponsor
- University of Oxford
Appendicitis Acute
Contrast-Enhanced Ultrasound Diagnosis of Acute Appendicitis
This study evaluates the ability of contrast-enhanced ultrasound to improve the diagnosis of acute appendicitis in children compared to conventional ultrasound.
- Trial name
- NCT03295656
- Testing
- Sulfur hexafluoride lipid-type A microspheres
- Where
- United States
- Sponsor
- Boston Children's Hospital
Appendicitis
TICAP - Titanium Clips for Appendiceal Stump Closure
Laparoscopic appendectomy is progressively accepted as the treatment of choice for acute appendicitis. Although the surgical technique of laparoscopic appendectomy has been well established, some controversy exists regarding the…
- Trial name
- TICAP (NCT01734837)
- Testing
- DS-Ligature Clip
- Where
- 9 sites in United States, Germany
- Volunteers
- 390 people
- Sponsor
- Aesculap AG
Cervical Cancer, Vulvar Cancer
Education, Immigration and HPV Vaccination: an Informational Randomized Trial
Counteracting misinformation on childhood vaccines remains a priority for public health in industrialized countries. Previous research showed that misinformation-induced vaccine hesitancy particularly concerns very highly or very…
- Conditions
- Cervical Cancer, Vulvar Cancer, Anus Cancer, Penis Cancer
- Trial name
- NCT04905030
- Testing
- Information T1, Information T2, Information C
- Where
- Sweden
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Intraabdominal Abscess, Wound Infection
Appendectomy in Children Performed by Residents in the Era of Laparoscopic Surgery
Introduction: An increasing proportion of childhood appendicitis is treated with laparoscopic appendectomy (LA). The investigators wanted to elucidate the outcome of childhood appendicitis treated primarily by residents in a…
- Trial name
- NCT01657565
- Where
- Denmark
- Volunteers
- 390 people
- Sponsor
- Odense University Hospital
Diarrhea
Effects of Probiotic in Treatment of Persistent Diarrhea in Children
Persistent diarrhea is a common health problem worldwide, particularly in low-income countries. Approximately 3% to 20% of acute diarrhea episodes in children under 5 years of age become persistent diarrhea.
- Trial name
- NCT05812820
- Testing
- LiveSpo DIA30, LiveSpo CLAUSY, RO
- Where
- Vietnam
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- National Children's Hospital, Vietnam
Gastrointestinal Cancer, Colorectal Cancer
GastroIntestinal Cancer in Children and Adolescents
The goal of this observational population-based cohort study is to investigate the clinical characteristics and outcomes of children and adolescents with primary gastrointestinal malignancies registered in the publicly available…
- Conditions
- Gastrointestinal Cancer, Colorectal Cancer, Gastric Cancer, Hepatoblastoma
- Trial name
- GICCA (NCT05693519)
- Where
- 2 sites in Netherlands
- Volunteers
- 2,500 people
- Sponsor
- Paul G. Kemps, MD
Acute Appendicitis
Laparoscopic Versus Open Appendectomy
Appendectomy is the most common surgical procedure performed in emergency surgery. Because of lack of consensus about the most appropriate technique, appendectomy is still being performed by both open (OA) and laparoscopic (LA)…
- Trial name
- NCT02867072
- Testing
- Open appendectomy, Laparoscopic appendectomy
- Volunteers
- 593 people
- Sponsor
- University of Catania
Dysentery, Dysentery, Bacillary
Safety Study of S.Flexneriza-S.Sonnei Bivalent Conjugate Vaccine in Healthy Volunteers Aged Above 3 Months
The purpose of this study is to evaluate safety of S.flexneriza-S.sonnei Bivalent Conjugate Vaccine in healthy volunteers aged above 3 Months.
- Trial name
- NCT03561181
- Testing
- S.Flexneriza-S.Sonnei Bivalent Conjugate Vaccine
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Beijing Zhifei Lvzhu Biopharmaceutical Co., Ltd