Clinical trials: Jaw Relationship
Medication Related Osteonecrosis of the Jaw
MRONJ and Polynucleotides-Hyaluronic Acid Hydrogel (Regenfast®)
Several circumstances or conditions, such as wound extension or disease, can affect the hard and soft tissue healing after surgical treatment of MRONJ. Supportive therapies are therefore needed to help tissues wound healing.
- Trial name
- REG-MRONJ-1 (NCT06984107)
- Testing
- MRONJ resection plus PN+HA
- Volunteers
- 10 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Stabilization of a Full Lower Denture, Edentulism in Lower Jaw
Clinical Evaluation of the Mandibular Mini-Implant Overdenture
Stabilization of existing full lower dentures by means of mini-dental implants (MDI). To test whether 4 mini-implants placed at the front of the lower jaw can stabilize an immediately-modified existing lower denture.
- Conditions
- Stabilization of a Full Lower Denture, Edentulism in Lower Jaw, Lower Denture Made Within Last Few Years
- Trial name
- NCT01064843
- Testing
- Imtec MDI
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Solventum US LLC
Osteonecrosis Due to Drugs, Jaw
Plasma Rich in Growth Factors for Treatment of Medication Related Osteonecrosis of the Jaw
Medication related Osteonecrosis of the Jaw (MRONJ) consists of progressive destruction of bone in the maxillofacial area. It is an established complication which occurs in patients who take two main classes of antiresorptive…
- Trial name
- NCT03390777
- Testing
- surgery, PRGF after surgery
- Volunteers
- 150 people
- Sponsor
- University of Roma La Sapienza
Temporomandibular Disorder, Adolescent Behavior
Parafunctional Habits and Temporomandibular Disorder in Adolescents
The disorders that affect the temporomandibular joint (TMJ) are responsible for the diverse symptoms. Objective: To evaluate whether or not the relationship between signs or symptoms of TMD and presence of harmful habits.
- Trial name
- NCT01331031
- Where
- Brazil
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Cleft Lip and Palate, Temporomandibular Disorder
Electromyographic Analysis of the Masticatory Muscles in Cleft Lip and Palate Children With Temporomandibular Disorders
The aim of this study was to assess the electrical activity of the temporal and masseter muscles in cleft lip and palate (CLP) children with pain-related temporomandibular disorders (TMD) and in CLP individuals with no TMD by…
- Trial name
- NCT03308266
- Testing
- electromyography
- Where
- Poland
- Volunteers
- 87 people
- Sponsor
- Pomeranian Medical University Szczecin
Temporomandibular Disorders, Orofacial Pain
Genetic Polymorphisms and Their Association With Temporomandibular Disorders
Temporomandibular disorders (TMD) are the most common orofacial pain disorders of non-dental origin with the prevalence of 6.1-10.2%, and incidence of 3.9%.
- Trial name
- GenPolTMD (NCT04694274)
- Testing
- stabilization splint, physical therapy
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Croatian Science Foundation
Text Neck Syndrome, Temporomandibular Joint Disorders
Comparison of Cervical and TMJ Parameters in Young Adults With and Without Text Neck Syndrome
The aim of this cross-sectional study is to compare temporomandibular joint (TMJ) and cervical spine parameters between young university students aged 18-30 years with and without text neck syndrome, a modern overuse condition…
- Conditions
- Text Neck Syndrome, Temporomandibular Joint Disorders, Postural Balance
- Trial name
- NCT07851805
- Volunteers
- 80 people
- Sponsor
- Borna Farhoomand
Scoliosis Idiopathic
Hip Related Functional Limitations in Individuals With Idiopathic Scoliosis
The aim of this study is to examine the functional parameters of hip and jaw in terms of scoliosis degree and scoliosis pattern in individuals with idiopathic scoliosis.
- Trial name
- NCT04677140
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Temporomandibular Joint Disorders
The Relationship of Orthodontic Malocclusions With Temporomandibular Joint Disorders
The patients who applied to the hospital for orthodontic treatment were asked various questions to evaluate their oral health related quality of life, malocclusions and self reported temporomandibular joint problems.
- Trial name
- NCT04123236
- Testing
- Age 0-18, Age 18-26, Girls
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- University of Gaziantep
Malignant Neoplasm, Musculoskeletal Complications
Genetics in Predicting Risk of Bisphosphonate-Related Osteonecrosis of the Jaw in Patients With Cancer Receiving Zoledronic Acid
This randomized clinical trial studies genetics in predicting risk of bisphosphonate-related osteonecrosis of the jaw in patients with cancer receiving zoledronic acid.
- Trial name
- NCT02069340
- Testing
- zoledronic acid, pharmacological study
- Where
- 2 sites in United States
- Sponsor
- University of Southern California
Temporomandibular Disorders (TMD)
Prevalence of Temporomandibular Joint Disorders in Wind Musicians
This study aims to analyze the prevalence of temporomandibular joint disorders (TMD) in wind musicians, differentiating the impact by instrument type (woodwind vs.
- Trial name
- TMD-WIND (NCT06823531)
- Testing
- Not applicable (Observational Study)
- Volunteers
- 50 people
- Sponsor
- University of Oviedo
Osteomyelitis of Jaw
Management of Medication Related Osteonecrosis of the Jaws With Double Periosteal Flap Closure
20 patients with MRONJ underwent surgical debridement using piezosurgery then closure using double periosteal flap
- Trial name
- NCT07177378
- Testing
- management of medication related osteonecrosis of the jaw
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tanta University
Medication-Related Osteonecrosis of Jaw
Assessment of Er:YAG Laser-Assisted Surgical Treatment in Medication-Related Osteonecrosis of the Jaw (MRONJ): A Clinical Trial
The aim of this study is assessing the effectiveness of the Er:YAG laser in relation to the use of conventional surgery in the treatment of drug-induced osteonecrosis of the jaws (MRONJ).
- Trial name
- NCT07029815
- Testing
- irradiation with Er:YAG laser, Tissue preparation
- Where
- Poland
- Volunteers
- 65 people
- Sponsor
- Wroclaw Medical University
Maxillary Hypoplasia
Maxillary Segment Tipping During Transpalatal Distraction
The investigator proposes a multi-centre study to investigate tipping of teeth, bringing into consideration the height of the osteotomy line and the height and placement of the transpalatal distractor as possible factors.
- Trial name
- NCT04041388
- Testing
- Conebeam CT
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Universitair Ziekenhuis Brussel
Temporomandibular Joint Disc Displacement
The Efficiency of Anterior Repositioning Splint for the Management of Temporomandibular Joint Dysunction
Intra-articular temporomandibular disorders are often related to pain in the area of temporomandibular joint, ear and temple. The aim of the study was to investigate the efficiency of anterior repositioning splints for the…
- Trial name
- NCT03057262
- Testing
- Repositioning splint
- Volunteers
- 112 people
- Sponsor
- Jagiellonian University