Clinical trials: Jaw Relationship
Jaw, Edentulous
Prospective Observational Study of SynCone® Concept
The aim of this prospective observational study will be to evaluate patient-related outcomes, clinical, microbiological and peri-implant immunoinflammatory mediators in completely edentulous patients rehabilitated with delayed…
- Trial name
- NCT03957265
- Testing
- Tapered abutment connection
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Marcio Zaffalon Casati
Apical Periodontitis, Atherosclerotic Cardiovascular Disease
Association Between Apical Periodontitis and Atherosclerotic Cardiovascular Diseases
The aim of the study is to evaluate the association between apical periodontitis (AP) and atherosclerotic cardiovascular disease (ASCVD) by assessing the multiplicative effect of AP on secondary outcomes of ASCVD.
- Trial name
- NCT05792787
- Testing
- Echo-color-doppler
- Where
- Italy
- Volunteers
- 65 people
- Sponsor
- University of Siena
Osteomyelitis of Jaw
Management of Medication Related Osteonecrosis of the Jaws With Double Periosteal Flap Closure
20 patients with MRONJ underwent surgical debridement using piezosurgery then closure using double periosteal flap
- Trial name
- NCT07177378
- Testing
- management of medication related osteonecrosis of the jaw
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tanta University
TMD, TMD/Orofacial Pain
Treatment Outcomes in Patients With Muscular Temporo-mandibular Joint Disorders
The aim of the present study was to assess the treatment outcomes in patients affected by M-TMDs in terms of pain scores assessed with pressure pain threshold (PPT).
- Trial name
- NCT06339736
- Testing
- Questionnaires administered to all study participants
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Temporomandibular Joint Disorders, Oral Habits
Temporomandibular Joint Dysfunction Prevalence and Oral Habits, Food Consumption Frequency and Eating Behaviour
This study was planned to investigate the prevalence of TMD in university students and to determine possible predisposition factors by evaluating oral habits, food consumption frequency and eating behaviors thought to be related…
- Conditions
- Temporomandibular Joint Disorders, Oral Habits, University Students
- Trial name
- NCT06768372
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Temporomandibular Joint Disorders
Nocipoint Therapy Versus Standard Physical Therapy Using Electrical Stimulation in Treating Pain From TMJ Disorder
The purpose of this study is to measure the effect of nocipoint therapy on patients with temporomandibular joint disorders (TMD) and compare it with the effect of standard electrical stimulation therapy.
- Trial name
- NCT01676129
- Testing
- Nocipoint Therapy, Physical Therapy
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Taiwan University Hospital
Edentulous Mouth, Edentulous Jaw
Mandibular Overdentures Retained by Conventional or Mini Implants
This study aims to compare mandibular overdentures retained either by mini or standard size implants as a treatment for edentulous adults, in terms of patient-reported satisfaction and oral health-related quality of life.
- Trial name
- NCT01411683
- Testing
- Implant-retained mandibular overdenture
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- University of Sao Paulo
Pain, Discomfort
Association Among Pain Perception, Severity of Temporomandibular Joint Dysfunction, and Spinal Health in Caregivers of Stroke Individuals
This study aims to examine pain perception, temporomandibular disorder severity and spine health in caregivers of stroke patients.
- Conditions
- Pain, Discomfort, Caregiver, Temporomandibular Disorder
- Trial name
- NCT06052735
- Testing
- Correlation research
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Periapical Periodontitis
Association of Apical Periodontitis With Hs-CRP and Hemogram Indices
There is lack of evidence on resolution of signs of systemic inflammatory markers by successful elimination of periapical inflammation by endodontic treatment.
- Trial name
- NCT04980768
- Testing
- Root canal treatment
- Where
- India
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Osteoporosis, With or Without Treatment, Bisphosphonate Treatment
Biomarker Identification in Orthopaedic & Oral Maxillofacial Surgery Subjects to Identify Risks of Bisphosphonate Use
Bisphosphonates are drugs that prevent bone loss by blocking the activity of cells that normally resorb bone. The most common examples of these drugs are Boniva and Fosamax.
- Conditions
- Osteoporosis, With or Without Treatment, Bisphosphonate Treatment, Atypical Femur Fracture, Bisphosphonate Related Osteonecrosis of the Jaws (BRONJ)
- Trial name
- NCT01875458
- Where
- United States
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Osteonecrosis of the Jaw
Leukocyte- and Platelet-Rich Fibrin in the Surgical Treatment of Medication-related Osteonecrosis of the Jaw
Medication-related osteonecrosis of the jaw (MRONJ) is a rare but serious side-effect of antiresorptive therapies used in the management of bone diseases, such as osteoporosis or bone metastases.
- Trial name
- PeRFOrMand (NCT06419010)
- Testing
- Surgery with the use of L-PRF, Standard surgery
- Where
- 7 sites in France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Toulouse
MEDICATION RELATED OSTEONECROSIS OF THE JAW
Infiltration of Medical Ozone for the Treatment of Medication-Related Osteonecrosis of the Jaws (MRONJ)
Medication-related osteonecrosis of the jaw (MRONJ) is a serious adverse reaction of antiresorptive and antiangiogenic agents; it is also a potentially painful and debilitating condition.
- Trial name
- OZOPROMAF (NCT05036837)
- Testing
- OZOPROMAF_SEQ1
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Stroke
Oropharyngeal and Trunk Muscle Interactions After Stroke
Background:This study aimed to investigate the effects of a short-term tongue-jaw-back isometric exercise program on these muscle groups and their interrelationships in the post-stroke period.
- Trial name
- NCT07261462
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people
- Sponsor
- Necmettin Erbakan University
Apical Periodontitis
Sclerostin Regulation in Apical Periodontitis Lesions in Apical Periodontitis Lesions
Our aim was to examine the relationship between inflammatory bone resorption associated with the severity of AP and gingival crevicular fluid (GCF) and blood sclerostin and PGE2 levels in cases of AP.
- Trial name
- NCT06512103
- Testing
- Apical periodontitis group
- Where
- Turkey (Türkiye)
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Bruxism, Myofascial Pain
Botulinum Toxin Type A Versus Oral Ibuprofen for Bruxism
This randomized controlled trial evaluated the effectiveness of Botulinum Toxin Type A compared with oral ibuprofen in reducing pain and improving oral health-related quality of life in patients with sleep bruxism and jaw muscle…
- Trial name
- NCT07732751
- Testing
- Botulinum Toxin Type A 100U, Ibuprofen
- Where
- Cyprus
- Volunteers
- 40 people
- Sponsor
- Cyprus Health and Social Sciences University
Chronic Kidney Diseases, Periapical Lesions
Association of Apical Periodontitis With Chronic Kidney Disease
This investigation is aimed to assess the prevalence and severity of apical periodontitis (AP) in different stages of CKD patients and its impact on the systemic (nutritional and inflammatory) markers was compared to healthy…
- Trial name
- NCT05818657
- Testing
- levels of CKD markers, Oral health status, apical periodontitis, systemic inflammatory marker, Oral health status, apical periodontitis
- Where
- India
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Medication-related Osteonecrosis of the Jaw
Autologous Platelet Concentrates on the Healing of Extraction Sockets
This study will evaluate the effect of A-PRF, a second-generation APC, on early wound healing in high-risk MRONJ patients following dental extractions, utilising advanced non-invasive methods to assess and associate molecular and…
- Trial name
- NCT07673848
- Testing
- Application of A-PRF into extraction socket
- Volunteers
- 44 people
- Sponsor
- Queen Mary University of London
Edentulous Jaw
Impact of Different Palatal Contour Designs on Patients' Satisfaction and Oral Health Related Quality of Life
The palatal rugae, refer to asymmetrical and irregular elevations of the mucosa located in the anterior third of the palate, on each side of the median palatal raphe and behind the incisive papilla.
- Trial name
- NCT04985747
- Testing
- Polished palatal surface, Roughened palatal surface, Opened palatal surface
- Where
- Jordan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Hamstring Injury, Temporomandibular Joint Disorders
Biomechanical Relationship Between Trunk Flexion and Mouth Opening: Pilot Study
The aim of the present study is to analyze if there is a biomechanical relationship between trunk flexion and buccal opening and to observe if there is an improvement of trunk flexion by performing the "sit and reach" test when…
- Conditions
- Hamstring Injury, Temporomandibular Joint Disorders, Stretch
- Trial name
- REFEM (NCT06188897)
- Testing
- Self-stretching of the masticatory musculature, Control group intervention
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Temporomandibular Disorders (TMD), Temporomandibular Joint Dysfunction Syndrome
Relationship Between Upper Cervical Mobility and Temporomandibular Joint Range of Motion in Patients With Temporomandibular Disorders
Upper cervical spine mobility plays a crucial role in temporomandibular joint (TMJ) function. This observational study investigates the relationship between upper cervical spine mobility and TMJ range of motion in patients…
- Conditions
- Temporomandibular Disorders (TMD), Temporomandibular Joint Dysfunction Syndrome, Cervicogenic Headache
- Trial name
- NCT07371195
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Deraya University